ADD THIS DRUG TO MY LIST

Select the drug indication to add to your list

DESFERAL
Poisoning/overdose
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:

DESFERAL Rx

Generic Name and Formulations:
Deferoxamine mesylate 250mg/mL; for inj after reconstitution.

Company:
Novartis Pharmaceuticals Corp

Therapeutic Use:

Indications for DESFERAL:

Acute iron intoxication. Chronic iron overload due to multiple transfusions.

Adults and Children:

Routes other than IM: see literature. <3yrs: not recommended. ≥3yrs: acute iron toxicity: 1g IM initially followed by 500mg every 4 hours for 2 doses; repeat every 4–12 hours if needed; max 6g/day. Chronic iron overload: see literature.

Contraindications:

Severe renal disease. Anuria.

Warnings/Precautions:

Ocular or auditory disturbances. Perform visual acuity tests, slit-lamp exams, funduscopy and audiometry with prolonged therapy. High doses in patients with low ferritin levels may retard growth. Acute respiratory distress syndrome with high IV doses. Flushing, urticaria, hypotension, and shock if given rapid IV. Monitor changes in renal function. Discoloration of urine. Elderly. Pregnancy (Cat.C). Nursing mothers.

Interactions:

Possible impairment of cardiac function with concomitant high dose Vit. C; give max adult dose: 200mg in divided doses. May cause temporary impairment of consciousness with prochlorperazine.

Pharmacological Class:

Iron chelating agent.

Adverse Reactions:

Localized skin reactions, hypersensitivity, tachycardia, hypotension, shock, dysuria, leg cramps, fever, GI upset; increased serum creatinine, acute renal failure, renal tubular disorder; rare: Yersinia infections, mucormycosis.

How Supplied:

Vials 500mg—4

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs