T-cell Lymphoma Survival Varies by Racial, Ethnic Group

A recent study examined the varying survival rates among US racial/ethnic patient groups with peripheral T-cell lymphoma subtypes.
A recent study examined the varying survival rates among US racial/ethnic patient groups with peripheral T-cell lymphoma subtypes.

A recent study examined the varying survival rates among US racial/ethnic patient groups with peripheral T-cell lymphoma subtypes.1

Researchers, based at the University of Washington School of Medicine, selected patients age 15 years or older. Approximately 13 107 patients with peripheral T-cell lymphoma (PTCL) were identified in the Surveillance, Epidemiology, and End Results (SEER) registries and were categorized by race/ethnicity.

The researchers categorized the patients as non-Hispanic white, black, Hispanic white, Asian/Pacific Islander, or American Indian/Alaskan native. SEER follow-up data (Cox regression) was used to estimate survival rate.

The annual incidence of PTCL was found to be greatest in the black group. Whites showed a lower incidence of PTCL not otherwise specified (PTCL-NOS), adult T-cell leukemia/lymphoma (ATLL), and anaplastic large-cell lymphoma, but a higher rate of angioimmunoblastic T-cell lymphoma (AITL) compared with blacks.

Both Asians/Pacific Islanders and Hispanics displayed higher incidence of AITL and NK-cell leukemia (ENKCL) compared to whites. Native Americans displayed the lowest annual PTCL incidence of all groups.

Survival rates varied by racial/ethnic group, and blacks showed a lower survival for most peripheral T-cell lymphoma subtypes.

Data from this study appeared in the Journal of Clinical Oncology.

REFERENCE

1. Adams SV, Newcomb PA, Shustov A. Racial patterns of peripheral T-cell lymphoma incidence and survival in the United States [published online ahead of print January 25, 2016]. J Clin Oncol. doi:10.1200/JCO.2015.635540.
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