Selenium, Vitamins C, E May Lower Pancreatic Cancer Risk

This article originally appeared here.
Selenium, Vitamins C, E May Lower Pancreatic Cancer Risk
Selenium, Vitamins C, E May Lower Pancreatic Cancer Risk

THURSDAY, July 26 (HealthDay News) -- Higher intakes of the antioxidants selenium and vitamins C and E reduce the risk of pancreatic cancer by two-thirds, according to a study published online July 23 in Gut.

Paul J.R. Banim, M.B.B.S., from the University of East Anglia in Norwich, U.K., and colleagues analyzed data from 23,658 participants aged 40 to74 years who participated in the EPIC-Norfolk Study and completed seven-day food diaries. A computer program calculated nutrient intakes in those later diagnosed with pancreatic cancer and in 3,970 controls.

The researchers found that, during a 10-year period, 49 participants (55 percent men) developed pancreatic cancer. There was a significantly decreased risk of pancreatic cancer among those eating a combination of the highest three quartiles of all of vitamins C and E and selenium (hazard ratio [HR], 0.33). For selenium and vitamin E there were threshold effects (quartile 2 to 4 versus quartile 1; HR, 0.49 and 0.57, respectively). For quartiles of antioxidants, excluding zinc, the HRs were less than 1.0, but were not statistically significant. There was a significant inverse association between serum measurements of vitamin C and risk (HR trend, 0.67), but the threshold effect from food diaries was not significant.

"The results support measuring antioxidants in studies investigating the etiology of pancreatic cancer," the authors write. "If the association is causal, one in 12 cancers might be prevented by avoiding the lowest intakes."

Abstract
Full Text (subscription or payment may be required)

Loading links....
You must be a registered member of ONA to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs