Cancer 'vaccine' for advanced disease shows early progress

Cancer 'vaccine' for advanced disease shows early progress

Early progress has been made in developing a treatment that might one day help the immune system defend itself against cancer, but research is still in preliminary stages.

Clinician-patient relationship tied to health care outcomes

Clinician-patient relationship tied to health care outcomes

Meta-analysis of 13 randomized controlled trials shows small but significant effect from the patient-clinician relationship.

Patients see sharp increase in price of specialty drugs

Patients see sharp increase in price of specialty drugs

Many Americans paying less for prescription drugs, but some are having to deal with sharp rises in cost of specialty meds.

Interval tumors found in six percent of colorectal cancer cases

Interval tumors found in six percent of colorectal cancer cases

Interval cancers more likely to be earlier stage, proximal, have lower risk of death

Reliance on Windows XP may threaten data security

Reliance on Windows XP may threaten data security

Continued security of patient data is needed following Microsoft's termination of XP support.

Perioperative chemotherapy increases bladder cancer survival

Perioperative chemotherapy increases bladder cancer survival

Study shows low utilization of bladder cancer perioperative chemotherapy is associated with a survival benefit in the general population.

Video-based education increases men's skin awareness

Video-based education increases men's skin awareness

Those receiving intervention increased clinical skin exams in the seven months following their education.

Colorectal cancer resection mortality still high for elderly

Colorectal cancer resection mortality still high for elderly

Despite an overall improved mortality seen during the past 10 years, advancing age is associated with higher morbidity and mortality in colorectal cancer resection.

New Health Secretary to Confront Health Care Reform Hurdles

New Health Secretary to Confront Health Care Reform Hurdles

The new nominee, Sylvia Mathews Burwell, will seek to burnish ACA's image amid the mid-term election fray.

Chronic pancreatitis increases risk of cancer death

Chronic pancreatitis increases risk of cancer death

People with chronic pancreatitis are at higher risk for cancer death and also have higher incidence of other comorbidities.

Fewer Americans overcome by medical bills

Fewer Americans overcome by medical bills

Reduced use of medical care, early health care reforms may be easing financial worries for Americans.

Faster cognitive decline lowers cancer mortality risk

Faster cognitive decline lowers cancer mortality risk

Elderly with faster cognitive decline were found to have lower risk of cancer mortality, according to research.

AACR: Irregular Menstrual Cycles Tied to Ovarian Cancer Risk

AACR: Irregular Menstrual Cycles Tied to Ovarian Cancer Risk

Irregular menstrual cycles may be an early marker of ovarian cancer risk, according to a study presented at the annual meeting of the American Association for Cancer Research.

AACR: Coffee consumption may lower liver cancer risk

AACR: Coffee consumption may lower liver cancer risk

Increased coffee consumption may reduce hepatocellular carcinoma (HCC) risk across ethnicities, according to a study.

Conventional chemotherapy may improve advanced NSCLC survival

Conventional chemotherapy may improve advanced NSCLC survival

For patients with non-small-cell lung cancer and wild-type EGFR mutations, conventional chemotherapy improves progression-free survival better than first-generation EGFR tyrosine kinase inhibitors.

AACR: LY2835219 shows promise for metastatic breast cancer

AACR: LY2835219 shows promise for metastatic breast cancer

The novel cell cycle inhibitor selective for the cyclin-dependent kinases CDK4 and CDK6 (CDK4/6), LY2835219, shows promise for metastatic breast cancer, according to a study.

High adenoma detection rate lowers interval colorectal cancer risk

High adenoma detection rate lowers interval colorectal cancer risk

Adenoma detection rate is inversely associated with risk of interval colorectal cancer.

DNA methylation markers ID bladder cancer recurrence

DNA methylation markers ID bladder cancer recurrence

For patients with noninvasive urothelial carcinoma, three DNA methylation markers are able to accurately predict tumor recurrence, according to a study.

Impact of fertility drugs on breast cancer risk examined

Impact of fertility drugs on breast cancer risk examined

Women with ever use of clomiphene have no increased breast cancer risk, although women undergoing multiple clomiphene cycles have an increased risk of invasive breast cancer.

Full-field digital mammography shows lower recall and biopsy rates

Full-field digital mammography shows lower recall and biopsy rates

Compared with screen-film mammography (SFM), full-field digital mammography is associated with reduced recall and biopsy rates, according to research.

Cutaneous melanoma outcomes worse for men living alone

Cutaneous melanoma outcomes worse for men living alone

Men living alone have more advanced cutaneous malignant melanoma (CMM) at diagnosis and have reduced CMM-specific survival, according to a study.

Financial burden of breast cancer greater for minorities

Financial burden of breast cancer greater for minorities

There is a increased likelihood of financial decline and privations in minorities compared with whites dealing with breast cancer.

Long-term outcomes following esophagectomy favorable

Long-term outcomes following esophagectomy favorable

Good nutritional status, quality of life, and satisfaction with eating seen at 10 years post-esophagectomy.

Next-gen sequencing to impact breast cancer care

Next-gen sequencing to impact breast cancer care

By utilizing NGS, breast cancer clinicians will know whether their patients carry high-risk mutations in genes, such as BRCA1 or BRCA2, before the start of treatment.

CDC: Fewer invasive cancer diagnoses in 2010

CDC: Fewer invasive cancer diagnoses in 2010

Although cancer incidence declined from 2009 to 2010, the majority of states still have not reached 2020 targets for reduced cancer incidence.

'White coat effect' proves less for nurses

'White coat effect' proves less for nurses

Mean blood pressures lower for nurses compared to readings made by doctors at same visit, according to research.

Home colon cancer test approval recommended by FDA

Home colon cancer test approval recommended by FDA

DNA analysis of stool boosts accuracy rate of Cologuard to more than 90 percent, researchers say.

NIH releases new online resource for end-of-life issues

NIH releases new online resource for end-of-life issues

The new NIH website offers insights into emotional, physical, and financial aspects of terminal care.

White House extends deadline for ACA enrollment

White House extends deadline for ACA enrollment

Applicants who cannot complete the process by the March 31 enrollment deadline will be given an extension.

Interactive phone messages aid cancer screening

Interactive phone messages aid cancer screening

Underserved Latina patients view interactive voice response (IVR) messages as an acceptable strategy to promote cancer screening, according to a study.

ASCO guideline update for sentinel node biopsy in breast cancer

ASCO guideline update for sentinel node biopsy in breast cancer

The American Society of Clinical Oncology (ASCO) has updated its 2005 guideline for use of sentinel node biopsy in early breast cancer.

Physicians mixed on genetic testing usage

Physicians mixed on genetic testing usage

Plans to use multiplex tumor genetic testing and attitudes about results disclosure vary, with no clear consensus among clinicians.

E-cigarette use does not accelerate smoking cessation

E-cigarette use does not accelerate smoking cessation

Baseline e-cigarette use does not significantly predict quitting smoking one year later or reduce cigarette consumption after one year, according to a study.

AAD: Skin cancer self-treatment detrimental

AAD: Skin cancer self-treatment detrimental

Most self-treatments for skin cancer result in poor cosmoses, and extensive tissue damage is observed in more than one-third of such cases.

Elevated morbidity long-lasting for childhood cancer survivors

Elevated morbidity long-lasting for childhood cancer survivors

The increased risk of a severe, disabling, life-threatening, or fatal health condition persists to age 50 years for many childhood cancer survivors.

Liquid nicotine for e-cigarettes can pose serious health threat

Liquid nicotine for e-cigarettes can pose serious health threat

A potent, liquid form of nicotine poses a serious and potentially deadly threat, but is sold legally in stores across the United States and online.

SGO: Bariatric surgery may lower uterine cancer risk

SGO: Bariatric surgery may lower uterine cancer risk

A history of bariatric surgery is associated with a reduction in the risk of uterine malignancy, whereas BRCA1 carriers have an increased risk of high-risk uterine cancer, according to two studies.

Patient requests affect clinician prescribing behavior

Patient requests affect clinician prescribing behavior

Patients requesting specific medications are more likely to be prescribed those medications, according to research.

Valproic acid use may reduce head and neck cancer incidence

Valproic acid use may reduce head and neck cancer incidence

Long-term use of valproic acid (VPA) is associated with a reduced risk of smoking-related cancers of the head and neck, according to a study.

Recent diabetes diagnoses linked to pancreatic cancer

Recent diabetes diagnoses linked to pancreatic cancer

There is a strong association between pancreatic ductal adenocarcinoma (PDAC) and recently diagnosed diabetes mellitus (DM), according to a systematic review and meta-analysis.

EBCC: Routine mammograms for most women 70 not beneficial

EBCC: Routine mammograms for most women 70+ not beneficial

More harm than good can result from mammogram breast cancer screenings for women aged 70 and older, and decision should be made case by case.

PADT does not lower mortality for localized prostate cancer

PADT does not lower mortality for localized prostate cancer

For localized prostate cancer, primary androgen-deprivation therapy does not prolong survival for the majority of men who have not received treatment with curative intent.

Oropharyngeal cancer symptoms vary by HPV status

Oropharyngeal cancer symptoms vary by HPV status

Initial symptom presentation seems to differ for human papillomavirus (HPV)-positive versus HPV-negative patients with oropharyngeal squamous cell carcinoma, according to a study.

Colorectal cancer rates for older adults continue to decline

Colorectal cancer rates for older adults continue to decline

Incidence rates for colorectal cancer have decreased by about 3 percent per year during the past decade.

BRCAPRO model may underestimate BRCA1/2 mutation risk

BRCAPRO model may underestimate BRCA1/2 mutation risk

Use of the BRCAPRO model for assessment of the likelihood of having a germline BRCA1/BRCA2 mutation may underestimate the risk of mutations, according to a study

Post-mastectomy radiation beneficial after mastectomy

Post-mastectomy radiation beneficial after mastectomy

Reductions seen in locoregional recurrence, overall recurrence, and breast cancer mortality when radiotherapy is employed after mastectomy and axillary dissection.

CT scans pinpoint gemcitabine response in pancreatic cancer

CT scans pinpoint gemcitabine response in pancreatic cancer

Transport properties identified on routine CT scans correlate with clinically relevant end points for patients with pancreatic ductal adenocarcinoma (PDAC) who receive preoperative gemcitabine chemoradiotherapy.

Multitarget DNA test sensitive for colorectal cancer

Multitarget DNA test sensitive for colorectal cancer

For patients at average risk of colorectal cancer, a multitarget DNA assay has better sensitivity, but worse specificity than fecal immunochemical test for those at average CRC risk.

Cancer patients with diabetes have higher mortality rates

Cancer patients with diabetes have higher mortality rates

The comorbid condition of diabetes may contribute to increased mortality in patients with cancer, according to research. Patients with diabetes treated with insulin have the highest mortality rate ratios after cancer diagnosis.

FDA panel unanimous on HPV test as Pap replacement

FDA panel unanimous on HPV test as Pap replacement

Experts voted 13-0 that a HPV test was safe and effective as first step in cervical cancer screening.

APS: Mindfulness Meditation Beneficial for Teens With Cancer

APS: Mindfulness Meditation Beneficial for Teens With Cancer

Mindfulness-based meditation is associated with a reduction in depressive symptoms in adolescents with cancer, with increased sleep quality for girls, according to a study.

Inhibitor idelalisib active in non-Hodgkin lymphoma

Inhibitor idelalisib active in non-Hodgkin lymphoma

The phosphatidylinositol-3-kinase delta inhibitor idelalisib shows antitumor activity in patients with indolent non-Hodgkin lymphoma and chronic lymphocytic leukemia.

Majority of U.S. oncologists dissatisfied with work-life balance

Majority of U.S. oncologists dissatisfied with work-life balance

About one-third of U.S. oncologists report being satisfied with work-life balance (WLB), which is lower than for other medical specialties. Women oncologists and those who devote greater time to patient care less likely to be satisfied.

FDA experts debate Pap test timing

FDA experts debate Pap test timing

Panel could recommend HPV test as a woman's new first option for cervical cancer screening.

ACA enrollment exceeds four million

ACA enrollment exceeds four million

More than four million Americans have signed up for health coverage through state and federal insurance marketplaces established by the Affordable Care Act. Enrollment period for coverage in 2014 ends March 31 for most Americans

ASCO: Demand for quality care increasing but millions lack access

ASCO: Demand for quality care increasing but millions lack access

Millions lack access to quality cancer care; one-quarter of uninsured forgo care because of costs.

Patients desire specific prostate cancer information

Patients desire specific prostate cancer information

Although patients with prostate cancer endorse multiple sources of information, they report greatest satisfaction with information from the treating physician about patient outcomes.

Erlotinib plus cisplatin-based chemoradiation promising for cervical cancer

Erlotinib plus cisplatin-based chemoradiation promising for cervical cancer

Treatment with epidermal growth factor receptor inhibitor erlotinib combined with cisplatin-based chemoradiation seems safe and effective for locally advanced cervical cancer, according to a study.

Nonmelanoma ups subsequent primary cancer risk

Nonmelanoma ups subsequent primary cancer risk

Record-linkage study shows increased risks for 26 cancer types, especially for younger people, for those with a history of nonmelanoma skin cancer.

AMA issues grants to address health disparities

AMA issues grants to address health disparities

The new initiatives focus on underserved populations, workforce diversity, and population health.

Prostatectomy lowers early prostate cancer mortality

Prostatectomy lowers early prostate cancer mortality

Risk of long-term mortality for those that undergo surgical treatment is lower, compared with men who choose watchful waiting.

Robot-assisted prostatectomy yields improved surgical margins

Robot-assisted prostatectomy yields improved surgical margins

Robot-assisted radical prostatectomy (RARP) is associated with improved surgical margin status compared with open radical prostatectomy (ORP) for intermediate- and high-risk disease.

Yoga increases QoL for breast cancer patients receiving radiotherapy

Yoga increases QoL for breast cancer patients receiving radiotherapy

For women with breast cancer, incorporating yoga into radiotherapy is associated with a lasting improvement in quality of life.

Cancer screening rates below Healthy People targets

Cancer screening rates below Healthy People targets

Rates of cancer screening and provider counseling are currently below the Healthy People (HP) 2020 targets, according to a study.

Nivolumab may extend advanced melanoma survival

Nivolumab may extend advanced melanoma survival

Acceptable long-term safety, positive therapy responses persist after drug discontinuation

Nurses able to perform colonoscopies equally well

Nurses able to perform colonoscopies equally well

Colonoscopy quality and safety are comparable for nurse and physician endoscopy trainees, according to a study.

Women-specific medical research still lacking

Women-specific medical research still lacking

Women are still underrepresented in research, and many current studies fail to report sex-specific outcomes.

Smoking and smoke exposure increase adverse pregnancy outcomes

Smoking and smoke exposure increase adverse pregnancy outcomes

Increased odds for spontaneous abortions, stillbirths, and ectopic pregnancies were seen for smokers, compared to never-smoking women.

Nurse education and workload affect patient mortality

Nurse education and workload affect patient mortality

An increase in workload increases odds of death, whereas an increase in percentage of nurses with degrees cuts death rates, research found.

Smoking impacts renal cell carcinoma survival

Smoking impacts renal cell carcinoma survival

For patients with clear cell renal cell carcinoma, smoking exposure adversely impacts cancer-specific survival and increases the risk of death from another cause.

More than 7 Million patient record breaches occurred in 2013

More than 7 Million patient record breaches occurred in 2013

Breaches of protected health information up 137.7 percent; most breaches due to theft.

Earlier ovary removal increases BRCA-associated survival

Earlier ovary removal increases BRCA-associated survival

Among women with mutations in BRCA1 or BRCA2, oophorectomy reduces the risk of developing ovarian, fallopian tube, or peritoneal cancer by 80 percent.

Multiple biopsies increase infection risk for prostate cancer patients

Multiple biopsies increase infection risk for prostate cancer patients

Men with prostate cancer on active surveillance should be informed of the risk of complications linked to repeated biopsies.

Educational video motivates older men to have skin exams

Educational video motivates older men to have skin exams

Older men are more likely to have a whole-body skin exam done by their physician if they watch a video on skin self-examination and skin awareness.

Rise in breast reconstructions in U.S.

Rise in breast reconstructions in U.S.

Use of breast reconstruction in women undergoing mastectomy for breast cancer increased significantly, from 46% in 1998 to 63% in 2007.

Health reform linked to fewer behavioral admissions

Health reform linked to fewer behavioral admissions

Emergency department visits for young people with behavioral health disorders increased less than other states after Massachusetts reform.

Adjuvant bevacizumab increases cervical cancer survival

Adjuvant bevacizumab increases cervical cancer survival

Adjuvant bevacizumab increases overall survival in cervical cancer, and two studies show benefits of bevacizumab on PFS in newly diagnosed glioblastoma as well.

Direct-to-consumer genomic testing concerns raised

Direct-to-consumer genomic testing concerns raised

Concerns related to direct-to-consumer genomic testing include lack of evidence for association studies being appropriate as screening tests.

Low recurrence breast cancer rates with negative margins

Low recurrence breast cancer rates with negative margins

Positive margins linked to two-fold increased risk of ipsilateral breast tumor recurrence, according to consensus guidelines.

Bilateral mastectomy reduces BRCA-related cancer mortality

Bilateral mastectomy reduces BRCA-related cancer mortality

Observational study supports removal of contralateral breast in women with hereditary breast cancer.

Sun protection to avoid skin cancer needed by all

Sun protection to avoid skin cancer needed by all

Photoprotection is necessary, and is also important for reducing photoaging and other UV-related skin disorders.

Annual mammography doesn't impact breast cancer mortality

Annual mammography doesn't impact breast cancer mortality

Annual mammography does not reduce mortality from breast cancer among 40- to 59-year-old women, according to recent research.

Affordable Care Act enrollment reaches 3.3 million

Affordable Care Act enrollment reaches 3.3 million

About one-quarter of those signed up through the state and federal marketplaces are now young adults, report shows.

Mid-sized companies granted extra year for ACA compliance

Mid-sized companies granted extra year for ACA compliance

In granting more time for compliance, the federal government set up new deadlines for three sizes of companies.

Metformin use doesn't reduce bladder cancer incidence

Metformin use doesn't reduce bladder cancer incidence

For patients with type 2 diabetes, metformin use is not associated with a significantly reduced risk of bladder cancer, according to a study.

Smoking increases ER-positive breast cancer risk for women

Smoking increases ER-positive breast cancer risk for women

Younger women who smoke appear to be at increased risk for developing ER-positive breast cancer, according to research, but no association found for risk of triple-negative breast cancer.

Patients now allowed to access lab test results

Patients now allowed to access lab test results

Final rule relating to HIPAA allows patient or personal representative to access results directly from the laboratory.

President's panel calls for increased HPV vaccine administration

President's panel calls for increased HPV vaccine administration

The HPV vaccine protects against cancers of the cervix, throat, rectum, and penis, but too few are receiving it.

Colon polyps more prevalent in obese men

Colon polyps more prevalent in obese men

Obese individuals have increased odds of having three or more polyps, as well as tubular adenomas.

Daily aspirin may lower ovarian cancer risk

Daily aspirin may lower ovarian cancer risk

A study of almost 20,000 women found the drug lowered ovarian cancer risk by 20 percent.

Maternal coffee consumption tied to childhood leukemia

Maternal coffee consumption tied to childhood leukemia

Linear dose-response relationship for acute lymphoblastic leukemia and acute myeloid leukemia has been observed.

OPSCC incidence up from 1973 to 2009

OPSCC incidence up from 1973 to 2009

Increased incidence of of oropharyngeal squamous cell carcinoma (OPSCC) among patients younger than 45 years seen, and steady increase in proportion of grade III/IV tumors.

Running tops walking for breast cancer survival

Running tops walking for breast cancer survival

Researchers found a significantly reduced mortality risk for breast cancer survivors who run.

High career satisfaction reported by oncologists

High career satisfaction reported by oncologists

Overall oncologists reported being very satisfied with their careers, but burnout is still a factor.

CVS phasing out all tobacco products

CVS phasing out all tobacco products

The company says sale of cigarettes is inconsistent with a pharmacy's mission.

Many Americans uninformed on cancer risks

Many Americans uninformed on cancer risks

Researchers surveyed 1,233 U.S. adults online regarding their risk of getting cancer and found many misperceptions.

First- and second-generation family cancer history essential

First- and second-generation family cancer history essential

Researchers note that a minimum adequate family history should include a history of cancer in first- and second-degree relatives.

Biomarker may help predict melanoma survival

Biomarker may help predict melanoma survival

High pretreatment VEGF levels have been linked to lower survival after ipilimumab treatment.

Expressive writing may assist renal cancer patients

Expressive writing may assist renal cancer patients

For patients with renal cell carcinoma, expressive writing may improve cancer-related symptoms and physical functioning, according to a study.

IBD associated with increased melanoma risk

IBD associated with increased melanoma risk

Meta-analysis based on cohort studies has found a link between IBD and increased risk of melanoma.

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