Patients age 65 years or older with recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC) did not have worse clinical outcomes.
Neratinib plus paclitaxel was not superior to trastuzumab plus paclitaxel with respect to progression-free survival as first-line treatment.
Structured Exercise Programs Effectively Lead to Increased Physical Activity Among Trial Participants
A structured exercise program more effectively increased physical activity among patients participating in a clinical trial.
Women who are long-term survivors of high-grade serous carcinoma (HGSC) usually have platinum-sensitive disease.
Dozens of targeted therapies, which are preferred as treatment over chemotherapy and surgery, suppress the activity of T cells that could help to fight tumors.
Cancer survivors use mind-body therapies (MBTs) to manage their cancer-related symptoms, but this use may differ for each cancer survivorship stage.
Ponatinib treatment was compared with imatinib in newly diagnosed patients with chronic myeloid leukemia in chronic phase (CP-CML).
Afatinib significantly improved outcomesin treatment-naïve patients with EGFR-mutant non-small cell lung cancer (NSCLC).
Use of neoadjuvant chemoradiotherapy (NACRT) before surgery among patients with rectal cancer has substantially increased over the past decade.
Women with breast cancer who used acupuncture plus enhanced self-care to manage their hot flashes were better able to manage their symptoms.
Sexual problems appear to be a prominent, and largely unaddressed issue for patients with myeloproliferative neoplasms.
Cancer programs are performing moderately well with regard to communicating the importance of psychosocial care to patients.
Women who received tamoxifen plus ovarian function suppression (OFS) reported worse endocrine symptoms and sexual functioning.
For patients with stage I to III HER2-positive breast cancer, the monoclonal antibody trastuzumab is central to their adjuvant therapy.
Stereotactic body radiotherapy (SBRT) should be offered to all patients with peripheral stage 1 non-small cell lung cancer (NSCLC).
Radiation doses to the bladder and rectum were reduced with intensity-modulated radiotherapy (IMRT) for prostate cancer.
High insulin levels but reduced levels of insulin-like growth factor binding protein (IGFBP)-3 were associated with increased risk for developing lung cancer.
Unmarried patients with a first primary, invasive cancer appear to have worse survival compared with married patients.
The presence of brain metastases in patients with nonmetastatic lung cancer is associated with worse survival for patients with non-small cell lung cancer (NSCLC).
A new guideline from the American Cancer Society provides recommendations on follow-up care for survivors of head and neck cancer.
A tailored high-dose oral vitamin D supplementation safely allows a higher proportion of patients to achieve a normalized vitamin D level.
The HER2 peptide AE37 vaccine did not demonstrate a benefit in patients with breast cancer with any degree of HER2 expression.
A sulindac-erlotinib combination reduced the burden and number of duodenal polyps in persons with familial adenomatous polyposis (FAP).
Nearly 50% of patients with stage II/III rectal cancer achieve a complete clinical response via neoadjuvant chemoradiation.
Gefitinib does not provide a comparable improvement in progression-free survival to erlotinib in the treatment of previously treated lung adenocarcinoma.
The combination of bicalutamide and everolimus may be effective in men with bicalutamide-naïve castration-resistant prostate cancer (CRPC).
Fifteen percent of older adults are at risk for a major drug-drug interaction due to increased use of prescription medications.
Patients with cancer who died at home had similar or longer survival compared with patients who died in a hospital.
Patients with a high risk for developing lung cancer and a negative low-dose computed tomography prevalence screen had a lower incidence.
Early MRI-based screening may reduce breast cancer mortality among women treated with radiation therapy for Hodgkin lymphoma.
Wellness programs offering a variety of supportive tools are needed for caregivers of patients with head and neck cancer.
Adding netupitant to a chemotherapy-induced nausea and vomiting (CINV) regimen can improve outcomes without increased toxicity.
Early changes in patient-reported outcomes during aromatase inhibitor (AI) therapy were associated with treatment discontinuation.
Current use of antihypertensive medication may be associated with a slightly increased risk for ovarian cancer.
Active screening and symptom management in patients with cancer reduces depression, pain, and fatigue.
Patients with head and neck cancer report using medical marijuana, by smoking, eating, or vaporizing.
Adding farletuzumab to carboplatin and a taxane failed to improve progression-free survival in patients with platinum-sensitive ovarian cancer.
A new study indicates that patient travel distance to an appropriate treatment facility can impact whether radiation therapy is received.
N3 nodal staging among patients with non-small cell lung cancer (NSCLC) was associated with a significantly higher risk for developing VTE.
Survival benefits were strongest for pemetrexed maintenance therapy followed by maintenance therapy with EGFR kinase inhibitors.
A popular mobile health (mHealth) app for a smartphone that measures blood pressure (BP) was found highly inaccurate.
Metabolic disorders contribute more to the incidence of hepatocellular carcinoma (HCC) incidence than any other risk factor.
Lymphocytosis is associated with higher response rates, significantly longer response durations, and improved overall survival.
Costs of care for elderly patients with myelodysplastic syndromes (MDS) enrolled in Medicare are not associated with survival.
Single-agent trametinib has therapeutic potential for RAS-mutated myeloid malignancies.
Hair and nail abnormalities are commonly associated with the Bruton tyrosine kinase inhibitor ibrutinib.
Both patient and nurse characteristics may be associated with discussions about complementary and alternative medicine (CAM).
Concurrent Chemoradiotherapy Improves Survival in Elderly Patients Head and Neck Squamous Cell Carcinoma
Age alone should not be a deterrant to concurrent chemoradiotherapy (CRT) for the treatment of head and neck squamous cell carcinoma (HNSCC).
Ramucirumab administered at a dose of 10 mg/kg every 21 days for 3 cycles did not produce significant prolongation of corrected QT (QTc).
Latino patients with advanced cancer who discussed their end-of-life (EOL) care with their clinicians were more likely to complete a do-not-resuscitate (DNR) order.
Bevacizumab plus irinotecan significantly improved the 6-month progression-free survival (PFS) rate and median progression-free survival.
Adding 6 months of adjuvant androgen suppression to radiotherapy improves biochemical and clinical disease-free survival (DFS).
RECIST v1.1 may underestimate the treatment response in patients with advanced melanoma treated with pembrolizumab.
The use of proton therapy to treat patients with prostate cancer increased more than 2-fold from 2004 to 2012.
Bevacizumab combined with docetaxel, oxaliplatin, and capecitabine (B-DOC) plus maintenance therapy was feasible and active.
Modest weight loss can reduce the likelihood of comorbid conditions in breast cancer survivors.
Patients with cancer seem to prefer to receive information regarding incidental germline variants found during the process of tumor profiling.
Cancer-related financial burden was linked to lower health-related quality of life (HRQoL).
Overall survival (OS) is worse for men with castration-resistant prostate cancer (CRPC) metastases to the lung and liver.
Paclitaxel and pemetrexed with bevacizumab (PPB) produced a high response rate as initial therapy in advanced lung adenocarcinomas.
Adjuvant treatment with sorafenib or sunitinib demonstrated no survival benefit in patients with resected local renal cell carcinoma at high risk for disease recurrence.
Gains in surgical proficiency in esophagectomy for cancer are associated with measurable improvements in short-term and long-term mortality results.
A higher proportion of cancer survivors in the United States report use of vitamins/minerals and complementary and alternative medicine (CAM).
Atezolizumab significantly improved overall survival compared with docetaxel and was well tolerated in non-small cell lung cancer (NSCLC).
The analgesia-first sedation approach is crucial to adequate pain management in critically ill oncology patients on mechanical ventilation.
Consuming a diet with a high glycemic index was independently associated with an increased risk for developing lung cancer.
Reduced intensity allogeneic hematopoietic cell transplantation (HCT) is an effective salvage treatment strategy in patients with follicular lymphoma.
Video-based patient education tool is an effective adjunct to printed materials and one-on-one counseling on post HSCT.
A recent study examined the risk of cardiovascular disease for the survivors of adolescent and young adult cancer.
Clinician communication with patients may help improve knowledge and reduce distress in some patients with incidental pulmonary nodules.
Induction therapy with nab-paclitaxel/carboplatin improved or maintained quality of life (QoL) for patients undergoing radiotherapy.
The prevalence of survivors of oropharyngeal cancer is rising in the United States.
Adding fosaprepitant to palonosetron and dexamethasone reduced the risk for nausea and emesis in patients undergoing radiotherapy.
Very few older man receive the intensity of active surveillance testing recommended by major prospective active surveillance (AS) programs.
Significant improvement was achieved in obtaining written informed consent and providing patient education.
Oral morphine, oxycodone, transdermal fentanyl, and buprenorphine provided similar pain control, response rates, in patients with cancer pain.
Approximately 1 in 4 survivors of breast cancer suffers from severe fatigue.
Among younger patients, thick melanomas may be commonly found in those with fewer total nevi but more atypical nevi.
Possible correlation between symptom burden for patients with lung or colorectal cancer and their financial issues.
Early weight loss in patients with non-small cell lung cancer (NSCLC) is associated with worse prognosis.
Type 1 diabetes was associated with differences in the risk for developing several common cancers.
A staffing template based on daily patient volume and hours of operation with defined nurse roles and responsibilities.
A substantial proportion of patients struggle to adhere to oral antineoplastic medications.
Chemosensory and food-related changes significantly impacted food preferences and had practical and social consequences.
The risk for developing colorectal cancer is increased after a diagnosis of prostate cancer.
FOLFOXIRI plus panitumumab is a feasible treatment strategy for patients with metastatic KRAS wild-type colorectal cancer with liver-only metastases.
Maintenance bevacizumab plus exemestane did not achieve longer progression-free survival.
Radium-223 dichloride (radium-223) improves overall survival in patients with castration-resistant prostate cancer (CRPC).
The severity of peripheral neuropathy is associated with lower vitamin D levels among patients with multiple myeloma.
Cytomegalovirus viremia is associated with an increased risk of death in the first year following hematopoietic cell transplantation (HCT).
Significant bone loss in children receiving chemotherapy for acute lymphoblastic leukemia (ALL) occurs during the first month of treatment.
Almost half of patients with metastatic HR-positive breast cancer treated with everolimus and exemestane required a dose reduction.
An in-depth look at the issues associated with the care reveals a need to improve how clinicians can help these women sort through their options.
Listening to guided meditation significantly reduced biopsy pain during imaging-guided breast biopsy.
Dasatinib, nilotinib, and ponatinib, used in the treatment of patients with chronic myeloid leukemia (CML) increase vascular occlusive events.
Identifying and reducing barriers to recommended treatment and surveillance in those at higher risk of mortality is essential.
Medication adherence rates are significantly improved when a mobile phone text message intervention is used to support adherence.
Minimally invasive hysterectomy does not appear to compromise long-term survival compared with abdominal hysterectomy.
Higher dietary fiber intake during adolescence and early adulthood may reduce the risk for developing breast cancer.
Risk for cardiovascular disease (CVD) in survivors of adult-onset cancer varies according to cancer type.
- Transforming the Care of Patients With Thyroid Cancer
- Immunotherapy Combination is Effective in Colorectal Cancer
- Blood Biomarker Is Predictive of Risk for Colon Cancer Recurrence
- Comprehensive Mental Health Screening Recommended for Some Childhood Cancer Survivors
- Trastuzumab Biosimilar Comparable the Monoclonal Antibody for Advanced HER2+ Breast Cancer
- Overall Benefits of Vaporized Nicotine Products Outweigh Harms, Says International Panel of Experts
- Implementing a Distress Screening Process for Cancer Patients
- Initiating Palliative Care in the Emergency Department
- Exercise is as Effective in Treating Metastatic Prostate Cancer as Medication
- Cancer-related Neuropathy May Respond to Gene Therapy
- Clinician Communication, Adherence to Protocols, and Presence of Pharmacists Improve Outcomes in ICUs
- Identifying Smaller ctDNA Fragments Improves Sensitivity of Liquid Biopsy
- Dual Antigen Targeting by CAR T Cells Improves Immunotherapeutic Technique
- Using Cognitive-Behavioral Therapy Principles in Daily Patient Interactions
- Decision Support and Shared Decision Making Help Patients Choose Plan for Low-Risk Prostate Cancer
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