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For older men with nonmetastatic prostate cancer, comorbidities increase risk of other-cause death mortality.
Increased polyp and adenoma detection rates are associated with use of full-spectrum endoscopy colonoscope.
High fitness has been linked to reductions in risk of developing and dying from lung, colorectal cancer.
Findings from a phase I study of concurrent ipilimumab and nivolumab for advanced melanoma
Older individuals with nonmelanoma skin cancer seem to have a significantly reduced risk of developing Alzheimer's disease, according to a Neurology study.
Genetech announced results from CLL11, a Phase 3 study of obinutuzumab (GA101), comparing the combination of either obinutuzumab or Rituxan and chlorambucil to chlorambucil alone in chronic lymphocytic leukemia (CLL).
Gilead announced Phase 2 results for idelalisib, an oral inhibitor of PI3K delta in combination with rituximab for older patients with treatment-naïve chronic lymphocytic leukemia.
Findings show younger cancer patients are increasingly vulnerable to bankruptcy.
Research shows discrepancies in the way the role of nurse practitioners is viewed.
The FDA has approved Xofigo (radium Ra 223 dichloride; Bayer) for the treatment of symptomatic late-stage castration-resistant prostate cancer with bone metastases.
The cobas EGFR Mutation Test, a companion diagnostic for Tarceva, has been approved by the FDA to detect lung-cancer-related gene mutation.
Significant associations seen in men's urinary and sexual function based on surgeon performing radical prostatectomy.
Review shows significant reductions in anxiety, depression, pain; improved QoL during treatment
The FDA has accepted Seattle Genetics' sBLA for filing of Adcetris for retreatment and extended duration beyond 16 cycles of therapy in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma.
Leukemia experts call for examination of the 'right' way to price life-saving drugs
Patients with metastatic prostate cancer who visit ER over the weekend have increased odds of death, compared with weekday visits.
For patients with chronic neutrophilic leukemia and atypical chronic myeloid leukemia, activating mutations in the gene encoding the colony stimulating factor 3 receptor are common.
MnDCT has similar radiation to X-ray but greater sensitivity for detecting new and recurrent cancer.
Phase 3 trial evaluating Vectibix vs. Erbitux for the treatment of chemo-refractory metastatic colorectal cancer meets its primary endpoint for overall survival.
The incidence of testicular germ cell tumors (TGCT) increased from 1992 to 2009, especially among Hispanic men.
The FDA is alerting health care professionals of possible medication errors resulting from confusing generic names for Kadcyla (ado-trastuzumab emtansine) and Herceptin (trastuzumab).
The FDA has designated Merck's lambrolizumab (MK-3475) as Breakthrough Therapy for the treatment of patients with advanced melanoma. Lambrolizumab is an investigational antibody therapy targeting Programmed Death receptor.
Having more comprehensive discussions about colorectal cancer screening with primary care providers (PCPs) is associated with increased odds of screening.
The U.S. Food and Drug Administration has announced the launch of a new interactive tool for educating patients, their advocates, and consumers about the processes involved in medication development.
Female smokers have a significantly increased risk of colon cancer, particularly for proximal colon cancer, compared to male smokers.
Women who have received cosmetic breast implants may have an increased risk of diagnosis at a non-localized stage of breast cancer, and seem to have worse breast cancer survival.
A novel structural and payment-reform system is proposed to foster accountable cancer care, according to a viewpoint piece published online April 29 in JAMA Internal Medicine.
There has been no change in mammography screening rates among women aged 40 years or older following publication of the 2009 U.S. Preventive Services Task Force (USPSTF) recommendations.
Overall, disease-specific survival is up for patients who undergo tonsil resection rather than biopsy.
The U.S. Preventive Services Task Force recommends that women who are at increased risk of primary breast cancer consider taking preventive medications such as tamoxifen.
The use of computer-aided detection (CAD) for screening mammography has increased in prevalence and is associated with increased diagnosis of ductal carcinoma in situ.
The incidence of pediatric melanoma has increased by about 2% per year, and this incidence trend is influenced by gender, age, and stage at diagnosis, primary site, and UV-B exposure.
A review suggests that optimal breast cancer screening should be personalized for each woman and may go beyond mammography.
Task force says more work is needed to see if tests can accurately detect oral cancer and improve outcomes.
For patients with papillary thyroid cancer (PTC), the presence of the BRAF V600E mutation is associated with increased cancer-related mortality.
A two-step immunotherapy approach and the experimental antibody-drug conjugate DMUC5754A show promise for advanced ovarian cancer, according to research presented at AACR 2013.
Preceptor and unit-base clinical specialists can guide paths to specialties and aid retention.
Intermittent androgen deprivation is linked to worse survival versus continuous; however, the results were statistically inconclusive.
Researchers have found that euthanasia legalization has led to fewer life-ending acts without the patient's request.
A study has found that duloxetine effectively decreases pain for patients with chemotherapy-related peripheral neuropathy, especially for those who received the drug as initial treatment.
Women whose family history not linked to BRCA mutations should not undergo genetic testing, according to a U.S. Preventive Services Task Force recommendation.
Breast cancer risk highest risk among women who initiate hormone treatment closer to menopause.
The best HPV screening programs maximize high-grade lesion detection without excessive testing.
Regardless of overall body weight, patients with high weight loss, low muscle index, and low muscle attenuation share a poor prognosis.
A JCO study has found that Lynch syndrome carriers have an almost two-fold cumulative chance of prostate cancer at ages 60 and 80 years.
A false-positive test result from screening mammography is not harmless and can result in negative long-term psychosocial consequences, according to research published in Annals of Family Medicine.
At no age is there an overall survival benefit associated with bilateral oophorectomy compared with ovarian conservation at the time of hysterectomy for benign disease.
Treatment with autologous engineered T cells is effective bridge to potentially curative therapy
For elderly patients with metastatic colorectal cancer, certain geriatric scores were predictive of severe toxicity or unexpected hospitalization after fluorouracil-based chemotherapy with or without irinotecan.
For women with a breast cancer diagnosis, high-fat dairy consumption is associated with a higher mortality risk, according to a Journal of the National Cancer Institute study.
Shift work may be associated with an increased risk of ovarian cancer, according to a study published in the April issue of Occupational & Environmental Medicine.
Immediate health risks supersede lifetime radiation-induced cancer risk in patients undergoing computed tomography surveillance for testicular cancer.
Oral melatonin does not improve appetite, weight, or quality of life for patients with cachexia due to advanced cancer.
Revisions to cervical cancer protocols may hinder clinicians diagnosing younger women with AIS
Relaxation, individual and group psychotherapy, and psychoeducation are linked to significant, small-to-medium effects on adult cancer patients' emotional distress and quality of life.
IP chemo improves long-term survival in advanced disease versus intravenous therapy
For postmenopausal Caucasian women, aspirin use is associated with a significantly reduced risk of melanoma.
Following a diagnosis of breast cancer, nearly one-quarter of women report symptoms of posttraumatic stress disorder, with an increased risk among blacks and Asians.
Many older adults consider cancer screening to be morally obligatory, but screening colonoscopy is often given inappropriately in the elderly.
Levels of three serum proteins are much higher in kidney cancer patients, lending a highly accurate diagnosis.
Prescribers of extended-release/long-acting opioid analgesics are encouraged to participate in continuing medical education provided by manufacturers of these analgesics.
To deal with the increasing demand for palliative care services, a coordinated palliative care model is proposed.
A study has found that serum levels of follicle-stimulating hormone and inhibin B are not good predictors of sperm levels in male survivors of childhood cancer.
Funding source, number of participants, and journal impact factor all affect time to publication.
Reduction of visceral fat through surgery or diet reduces intestinal tumors in mice, with clear differences between males and females.
Although low-risk bladder cancer rarely escalates to muscle invasion, it is associated with an increased risk of disease-specific mortality compared with the general population.
Using a classification strategy, all patients were event-free at a median 71 months of follow-up.
Second study shows use of electronic health records increases uptake of CRC screening.
Four cancers (prostate, breast, colorectal, lung) account for more than 50 percent of new cases.
Increase in breast cancer with distant involvement seen for young U.S. women of all races/ethnicities.
Obesity, physical activity are significantly linked to risk of CTNNB1-negative colorectal cancer.
Regorafenib approved for inoperable or metastatic gastrointestinal stromal tumors.
Adoption of National Lung Screening Trial regimens could prevent 12,250 deaths/year in U.S.
In contemporary practice, medical oncologists use novel anticancer agents on-label more often than off-label.
Fourth drug approved targeting HER2 protein; slows disease progression, prolongs survival.
Case vignette highlights issues relating to smoking marijuana when conventional treatment has failed.
The risk of developing therapy-related acute myeloid leukemia after chemotherapy varies depending on initial cancer and treatment practices.
Anticoagulant use is associated with improved survival in men receiving docetaxel chemotherapy for treatment of metastatic castration-resistant prostate cancer, according to research presented at the 2013 Genitourinary Cancers Symposium.
Use of finasteride reduces the risk of a prostate cancer diagnosis, but does not significantly affect mortality rates after following men for 18 years, found research presented at the 2013 Genitourinary Cancers Symposium.
A two-step irradiance protocol minimizes pain while maintaining positive clinical outcomes in patients with non-melanoma skin cancer lesions.
Falsified and substandard medications pose public health problems around the world, and international action should be taken to combat the phenomenon.
Survivors of some cancers receive different quality of care on acute and chronic indicators.
Net survival from TNM stage I and IV disease, 16 and 10 percent lower in UK versus Sweden.
Use of biennial strategy with longer interval for low PSA levels reduces tests, false-positive results.
Current recommendations for the assessment and management of female reproductive complications following treatment of cancers in childhood, adolescence, and young adulthood have been updated.
Despite progress, five-year survival still lower for African-Americans at each stage of diagnosis.
Fewer Medicare beneficiaries are dying in the setting of acute care hospitals, but health care transitions and intensive care unit utilization are increasing in the last month of life.
The first generic version of the cancer drug Doxil (doxorubicin hydrochloride liposome injection) has been approved by the U.S. Food and Drug Administration, which says the action should help relieve shortages of the brand-name medication.
Interpretative errors more common in radiologist malpractice suits versus communicative/procedural.
Bright IDEAS problem-solving skills training improves mood, anxiety, and posttraumatic stress in mothers of children recently diagnosed with cancer.
During critical time points or progression, palliative care emphasizes psychosocial aspects.
Over two-year follow-up, more cancers detected in men in dutasteride arm versus placebo arm.
Both overall and disease-specific survival improved with breast conserving therapy versus mastectomy.
The anti-cancer drug Gleevec (imatinib) has received new U.S. Food and Drug Administration approval to treat children newly diagnosed with Philadelphia chromosome positive acute lymphoblastic leukemia.
Patients diagnosed with type 2 diabetes have a greater prevalence of cancer with longer diabetes duration and with insulin use.
Three-dimensional stereoscopic digital mammography (DM) significantly improves the specificity and accuracy of breast cancer detection, with a lower patient recall rate and a sensitivity comparable to that of standard DM in a high-risk population.
In metastatic lung cancer patients, bone and chest radiotherapy doses are higher than recommended.
In synovial sarcoma, metastasis development is linked to chromosome complexity.
Physicians' practice styles related to informed decision-making for prostate-specific antigen (PSA) screening are linked to their personal beliefs about screening.
Improvement in reader performance is seen with an interactive computer-aided decision support tool.
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