Combination treatments show promise for metastatic melanoma

Combination treatments show promise for metastatic melanoma

Nivolumab and dabrafenib plus trametinib up survival in melanoma without, with BRAF, respectively.

Variation seen in number of cancer survivors undergoing HIV testing

Variation seen in number of cancer survivors undergoing HIV testing

Proportion undergoing testing varies by demographic and health-related factors, and by state, a study found.

AHA: Even with weight gain, smoking cessation ups survival

AHA: Even with weight gain, smoking cessation ups survival

Research indicates smoking cessation boosts survival, even if there has been a weight gain.

Telephone Support Intervention Beneficial for BRCA Carriers

Telephone Support Intervention Beneficial for BRCA Carriers

Reduction in distress, unmet information needs with telephone-based, peer-support program

Physicians feeling more positive about the Affordable Care Act (ACA)

Physicians feeling more positive about the Affordable Care Act (ACA)

There has been an increase in physicians grading health care reform as "A" and a decrease in those grading it as a failure, according to recent survey data.

Video-based tool informs patients about prostate health

Video-based tool informs patients about prostate health

A video-based educational tool increased comprehension of prostate health terms in patients with a mean literacy level of 7th grade or higher.

Prices soaring for some generic drugs in United States

Prices soaring for some generic drugs in United States

Supply and manufacturing problems, plus fewer companies in the market are among the causes for soaring generic prices.

Ezetimibe not tied to higher cancer risk or mortality

Ezetimibe not tied to higher cancer risk or mortality

Findings based upon 21 months of follow-up from original SEAS lipid therapy trial did not find the lipid-lowering therapy ezetimibe/simvastatin to be associated with an increased risk of developing cancer.

Cancer patients in hospice less likely to receive aggressive treatment

Cancer patients in hospice less likely to receive aggressive treatment

Researchers found that non-hospice patients used significantly more health care resources, mainly for acute conditions not directly related to their cancer.

Urologists key to informing patients of tobacco-bladder cancer link

Urologists key to informing patients of tobacco-bladder cancer link

Active smokers more knowledgeable than former smokers or nonsmokers, and often cite urologist as source of information.

CDC: Skin cancer treatment costs doubled within a decade

CDC: Skin cancer treatment costs doubled within a decade

The rapidly escalating costs of skin cancer treatment outstripped other cancer type treatment costs, increasing five times faster. The findings underscore importance of prevention efforts.

Large percentage of nursing students demonstrate hazardous drinking

Large percentage of nursing students demonstrate hazardous drinking

In nursing students, dangerous drinking is prevalent, and more problem drinking among younger students and smokers.

Lung cancer screening with computed tomography (CT) can be cost-effective

Lung cancer screening with computed tomography (CT) can be cost-effective

Benefit seen in long-term smokers when CT testing is done by skilled experts.

Colorectal cancer rates increasing for U.S. adults under 50

Colorectal cancer rates increasing for U.S. adults under 50

Reasons behind this colorectal cancer trend are unclear, and it's happening even as rates decline among older Americans.

Many women are not screened for cervical cancer despite need

Many women are not screened for cervical cancer despite need

The CDC notes that more than half of cervical cancer cases occur among women never or rarely screened.

Combination therapy for advanced melanoma found to increase survival

Combination therapy for advanced melanoma found to increase survival

Pairing ipilimumab with sargramostim gives patients about five extra months survival time for patients with advanced melanoma, researchers report.

ASCO endorses guideline for adjuvant and salvage radiotherapy after prostatectomy

ASCO endorses guideline for adjuvant and salvage radiotherapy after prostatectomy

The endorsed guideline outlines use of adjuvant and salvage radiotherapy after surgery for prostate cancer.

Repeated annual FITs may be viable alternative to colonoscopy

Repeated annual FITs may be viable alternative to colonoscopy

Annual FIT IDs all colorectal cancer, and may be equivalent to colonoscopy in detecting advanced neoplasia in first-degree relatives of patients with colorectal cancer (CRC).

ASTRO: Reducing biopsy could slash diagnosis costs for lung cancer

ASTRO: Reducing biopsy could slash diagnosis costs for lung cancer

For patients not diagnosed with cancer, the median diagnostic cost per patient was about 28 times higher for those with versus without biopsy.

Link between obesity and breast cancer confirmed for blacks and Hispanics

Link between obesity and breast cancer confirmed for blacks and Hispanics

For black women and Hispanic women, obesity increases postmenopausal risk of estrogen receptor (ER)-negative and progesterone receptor-positive breast cancer.

MicroRNAs can accurately identify pancreatic cancer

MicroRNAs can accurately identify pancreatic cancer

Increased expression of a microRNA (miRNA) panel seems highly accurate for diagnosis of pancreatic ductal adenocarcinoma (PDAC), according to a study published online.

AMA: Health insurer competition lacking in many regions

AMA: Health insurer competition lacking in many regions

A significant absence of health insurer competition was seen in 72 percent of the metropolitan areas examined.

Generic aromatase inhibitors may help breast cancer patients stick to therapy

Generic aromatase inhibitors may help breast cancer patients stick to therapy

Cost is a key factor for women to maintain their hormone treatment regimen, researchers report.

Digital mammography plus tomosynthesis cost-effective for dense breasts

Digital mammography plus tomosynthesis cost-effective for dense breasts

The combined breast screening cost-effective over a range of incremental improvements in test performance.

Radiologist performance improved on own recalled mammogram screens

Radiologist performance improved on own recalled mammogram screens

The researchers found that the sensitivity, false-positive rate, and cancer detection rate of screening mammography increased with increasing numbers of radiologist work-ups for their own recalled mammograms.

Knowledge of genetic colorectal cancer risk doesn't affect behavior

Knowledge of genetic colorectal cancer risk doesn't affect behavior

Those who know they have greater risk of colorectal cancer were found no more likely to be screened than others at lower risk, according to research.

Challenges exist in treating HPV oropharyngeal cancer patients

Challenges exist in treating HPV oropharyngeal cancer patients

Mixed views have been expressed in relation to explaining the causal role of HPV in oropharyngeal cancer.

ASCO: Burnout prevalent among palliative care clinicians

ASCO: Burnout prevalent among palliative care clinicians

A majority of of palliative care clinicians report burnout, according to a study, with the greatest risk of burnout for younger clinicians and those working more than 50 hours per week

Views on Affordable Care Act split by political affiliation

Views on Affordable Care Act split by political affiliation

Health care is third most important issue to Americans in fall elections, according to polls

Poor staging linked to mortality in bladder cancer

Poor staging linked to mortality in bladder cancer

In cases of bladder cancer, omission of muscle in specimen or its mention in pathology report is linked to increased mortality.

Daily aspirin may lower mortality in nonmetastatic prostate cancer

Daily aspirin may lower mortality in nonmetastatic prostate cancer

Even a small daily dose of aspirin may help lower mortality among men with nonmetastatic prostate cancer, according to research.

Irinotecan plus bevacizumab ups outcome for metastatic colorectal cancer (CRC)

Irinotecan plus bevacizumab ups outcome for metastatic colorectal cancer (CRC)

Findings show benefits compared with FOLFIRI for patients with untreated metastatic disease.

ASCO: Coping strategies typically employed for cancer-related financial distress

ASCO: Coping strategies typically employed for cancer-related financial distress

Most patients use lifestyle-altering strategies and about 40 percent adopt a care-altering strategy to manage financial distress associated with their cancer care.

Hospice increase doesn't offset end-of-life care for ovarian cancer

Hospice increase doesn't offset end-of-life care for ovarian cancer

Findings among older patients with terminal ovarian cancer showed that an increase in hospice care did not offset intensive end-of-life care in older women.

Benefit seen for adding trastuzumab to breast cancer chemotherapy

Benefit seen for adding trastuzumab to breast cancer chemotherapy

Herceptin in addition to chemotherapy boosts survival, reduces risk of cancer recurrence

Unplanned hospitalizations among gastrointestinal cancer patients common

Unplanned hospitalizations among gastrointestinal cancer patients common

Among elderly patients with gastrointestinal cancer, unplanned hospitalizations are common, according to online research.

70-Gene signature not likely to be cost-effective for breast cancer

70-Gene signature not likely to be cost-effective for breast cancer

Findings in comparative economic analysis of patients with node-negative breast cancer showed the 70-gene signature is unlikely to be cost-effective for guiding adjuvant chemotherapy decision making.

Many clinicians feel mobile apps can improve patient outcomes

Many clinicians feel mobile apps can improve patient outcomes

Many physicians believe digital communication technologies, including mobile apps, can be of benefit to their patients.

Overdetection of PSA recurrence after radical prostatectomy more likely in older patients

Overdetection of PSA recurrence after radical prostatectomy more likely in older patients

For some men, prostate cancer recurrence may be overdetected, especially in those aged over 70.

Medicare subsidy program helps breast cancer patients afford treatment

Medicare subsidy program helps breast cancer patients afford treatment

'Extra Help' program allows more women of varying racial and ethnic backgrounds to continue their hormone therapy.

Nearly 5 percent of cancer patients die a month after surgery

Nearly 5 percent of cancer patients die a month after surgery

In a study of more than 1.1 million cancer patients who had surgery, almost 5 percent died within one month of their operation. Lack of access to quality care a major factor in these deaths, researchers say.

Elevated cholesterol associated with prostate cancer recurrence

Elevated cholesterol associated with prostate cancer recurrence

Findings suggest that elevated levels of cholesterol and triglycerides may be linked with greater risk of the prostate cancer recurrence, but normalization of blood fats may reduce risk.

Laxative type might alter colorectal cancer risk

Laxative type might alter colorectal cancer risk

Fiber-based formulations seem to lower the odds for developing colorectal cancer, non-fiber products seem to raise them.

Ovarian cancer mutations may be detected in vaginal fluid

Ovarian cancer mutations may be detected in vaginal fluid

Preliminary finding may bring doctors one step closer to and ovarian cancer screening test.

Cancer diagnosis often adversely affects mental health

Cancer diagnosis often adversely affects mental health

Patients diagnosed with breast cancer, head and neck cancer, and malignant melanoma are particularly at risk for disorders such as anxiety or depression.

Study reviews LMWH treatment for cancer-related deep vein thrombosis

Study reviews LMWH treatment for cancer-related deep vein thrombosis

Presence of residual vein thrombosis may help determine the optimal duration of anticoagulant therapy in cancer patients with deep vein thrombosis (DVT) of the lower limbs.

Use of bone morphogenetic protein (BMP) in spinal arthrodesis doesn't increase cancer risk

Use of bone morphogenetic protein (BMP) in spinal arthrodesis doesn't increase cancer risk

No increased invasive cancer risk from bone morphogenetic protein exposure in men or women has been observed.

Low-dose computed tomography an effective lung cancer screening technique

Low-dose computed tomography an effective lung cancer screening technique

Low-dose computed tomography has been determined to be both an effective and low cost means of detecting lung cancer in Medicare beneficiaries.

HPV vaccine could prevent most cervical cancers

HPV vaccine could prevent most cervical cancers

Research suggests the human papillomavirus (HPV) vaccine could prevent 90 percent of cervical malignancies.

Providers received billions from drug and device companies

Providers received billions from drug and device companies

Doctors, hospitals received billions of dollars from drug and device makers in second half of 2013, according to the new Open Payments program (created under the Affordable Care Act).

Increased toxicity seen in many newly approved anticancer drugs

Increased toxicity seen in many newly approved anticancer drugs

Managing toxicity costs are higher for treatment with less-specific targeted agents and chemotherapies.

Professional liability for not performing esophageal cancer screening low

Professional liability for not performing esophageal cancer screening low

Risks of claims alleging failure to screen for esophageal cancer arising from acts of commission, omission are similarly low.

AACR: Dim light at night may increase breast cancer tumor resistance

AACR: Dim light at night may increase breast cancer tumor resistance

Tumors in rodents exposed to dim light seemed to develop resistance to a common cancer drug.

Obesity linked to greater secondary cancer risk for colorectal cancer survivors

Obesity linked to greater secondary cancer risk for colorectal cancer survivors

A higher obesity-driven risk of secondary cancer has been identified for kidney, pancreatic, esophageal, endometrial cancers.

ESMO: Herceptin may be best option for HER2 breast cancer treatment

ESMO: Herceptin may be best option for HER2+ breast cancer treatment

Drug should remain standard of care for HER2-positive tumors, according to new research.

ESMO: Combination treatments increase metastatic melanoma survival

ESMO: Combination treatments increase metastatic melanoma survival

Studies show improved progression-free melanoma survival for both cobimetinib combined with vemurafenib, and dabrafenib combined with trametinib.

Lung infections may lessen chance of detecting lung cancer

Lung infections may lessen chance of detecting lung cancer

Certain conditions make it harder to reliably detect tumors, and regions with locally-endemic infectious lung diseases pose an added hurdle for lung cancer detection.

Report identifies new directions for U.S. health care

Report identifies new directions for U.S. health care

A report from the IMS Institute for Healthcare Informatics notes 10 "harbingers of change" expected to alter the delivery of health care and medicine use over the next decade.

E-cigarettes don't help cancer patients stop smoking

E-cigarettes don't help cancer patients stop smoking

Smokers with cancer who used e-cigarettes along with traditional cigarettes were more dependent on nicotine, and the long-term safety of the devices still unclear, researchers caution.

Pancreatic cancer risk not increased with dipeptidyl-peptidase-4 inhibitors (DPP-4i)

Pancreatic cancer risk not increased with dipeptidyl-peptidase-4 inhibitors (DPP-4i)

Findings based on comparison to sulfonylureas and thiazolidinediones

Wild berry may up chemotherapy effectiveness for pancreatic cancer

Wild berry may up chemotherapy effectiveness for pancreatic cancer

Chokeberry extract enhances cytotoxicity of gemcitabine on a single cancer cell line, according to research.

ASTRO: Sexual function not compromised in prostate cancer combo treatment

ASTRO: Sexual function not compromised in prostate cancer combo treatment

High rates of preserved sexual function seen with combination beam plus brachytherapy for prostate cancer.

Screening elderly women for breast cancer not efficacious

Screening elderly women for breast cancer not efficacious

Mammograms for those aged 69 to 75 could result in over-treatment, researchers caution.

AACR: Targeted drugs and prevention reduce cancer mortality

AACR: Targeted drugs and prevention reduce cancer mortality

About 14.5 million U.S. cancer survivors are alive today, but aging population and increasing obesity threaten progress.

ASTRO: Radiotherapy helps remedy dysphagia in esophageal cancer

ASTRO: Radiotherapy helps remedy dysphagia in esophageal cancer

For patients with advanced esophageal cancer, dysphagia is improved with radiotherapy alone, according to a study.

ASTRO: Prostate cancer recovery faster with less androgen deprivation therapy

ASTRO: Prostate cancer recovery faster with less androgen deprivation therapy

Shorter time to testosterone recovery with 18 versus 36 months androgen deprivation therapy.

Over a quarter of hospital orders were classified as defensive

Over a quarter of hospital orders were classified as defensive

More than 25% of hospital medicine services were rated by ordering physicians as at least a partially defensive order, according to recent data.

Chest radiation may be useful for combating advanced lung cancers

Chest radiation may be useful for combating advanced lung cancers

The addition of chest radiation reduces recurrence rate and, improves survival when added to chemo in extensive stage small-cell lung cancer.

Market changes needed as patients take on greater care costs

Market changes needed as patients take on greater care costs

As consumers take on more costs of care, access to data for informed decisions is deemed crucial.

For black men with prostate cancer, watchful waiting may be unwise

For black men with prostate cancer, watchful waiting may be unwise

For men with early-stage prostate cancer, watching waiting is not always the best course of action, especially for black patients.

Half of staff feel dignified death is a possibility in cancer centers

Half of staff feel dignified death is a possibility in cancer centers

Compared with staff from other wards, palliative care staff reported much better conditions for the dying, with 95 percent indicating that patients die with dignity in palliative care wards.

ACCR: Oral olaparib with chemotherapy beneficial for ovarian cancer

ACCR: Oral olaparib with chemotherapy beneficial for ovarian cancer

Olaparib has been deemed safe in combination with carboplatin/paclitaxel in advanced ovarian cancer.

Meta-Analysis: Prediabetes tied to increased risk of cancer

Meta-Analysis: Prediabetes tied to increased risk of cancer

Prediabetes has been linked to an increased risk of cancer overall and with increased risks of site-specific cancers, including liver, endometrial, and stomach/colorectal cancer.

Joint ASCO/CCO guidelines for advanced prostate cancer issued

Joint ASCO/CCO guidelines for advanced prostate cancer issued

Recommendations are for men whose tumors have grown resistant to hormonal therapies were issued jointly by the American Society of Clinical Oncology (ASCO) and Cancer Care Ontario (CCO) in Canada.

Health care spending rise expected over next decade

Health care spending rise expected over next decade

Insurance coverage under ACA, population aging, and economic growth will likely drive future spending increases.

Soy may be detrimental for women with breast cancer

Soy may be detrimental for women with breast cancer

Study raises questions about the effect of soy's estrogen-like properties.

New myeloma treatment options promising

New myeloma treatment options promising

New multiple myeloma treatment options have shown promise for patients aged 65 years and younger and for newly diagnosed individuals ineligible for stem-cell transplantation, according to two studies.

Melanoma incidence higher in airline pilots and crew

Melanoma incidence higher in airline pilots and crew

Airline pilots and cabin crew have an increased incidence of melanoma, nearly twice that of the general population, according to a meta-analysis published online.

ASCO: Family doctors can improve mammogram return rates

ASCO: Family doctors can improve mammogram return rates

Women overdue for mammogram respond better to postcard plus reminder letter from family physician.

Guidelines issued for HER2-negative breast cancer

Guidelines issued for HER2-negative breast cancer

Evidence-based recommendations have been developed for chemotherapy and targeted therapy for women with HER2-negative advanced breast cancer.

ASCO: Angelina Jolie announcement responsible for BRCA1/2 testing boost

ASCO: Angelina Jolie announcement responsible for BRCA1/2 testing boost

Celebrity story helped double rates of genetic testing in following six months at one cancer center.

ASCO: Risks greater for double mastectomy

ASCO: Risks greater for double mastectomy

Women with breast cancer who have a double mastectomy are at higher risk of certain complications than those who have a single mastectomy, though the overall complication rate associated with breast cancer surgery is small.

ASCO: Factors that influence contralateral preventive mastectomy

ASCO: Factors that influence contralateral preventive mastectomy

Survey of women with breast cancer explores factors in the decision to remove a healthy breast as a measure to prevent breast cancer.

Bilateral mastectomy rates rise from 1998 to 2011

Bilateral mastectomy rates rise from 1998 to 2011

Bilateral mastectomy-linked mortality rates are up for women diagnosed with stage 0 to III breast cancer.

Factors associated with late hospice admission for cancer patients identified

Factors associated with late hospice admission for cancer patients identified

For patients with cancer, late admission more likely for younger patients, married men, hematologic malignancies.

Risk of diabetes elevated in Hodgkin lymphoma survivors

Risk of diabetes elevated in Hodgkin lymphoma survivors

Para-aortic radiation correlates with increased diabetes mellitus (DM) risk for Hodgkin's lymphoma (HL) survivors, according to a study.

United Nations' World Health Organization (WHO) recommends indoor e-cigarettes ban

United Nations' World Health Organization (WHO) recommends indoor e-cigarettes ban

WHO recommendation came a day after similar calls for e-cigarette regulation by American Heart Association.

American Heart Association (AHA) issues guidelines for electronic cigarette use

American Heart Association (AHA) issues guidelines for electronic cigarette use

AHA supports inclusion of e-cigarettes in state and federal laws prohibiting sale and marketing to minors.

Colonic diverticular disease not linked to subsequent colorectal cancer

Colonic diverticular disease not linked to subsequent colorectal cancer

Increased risk of subsequent colorectal cancer (CRC) in first year of diagnosis may be a screening effect, according to research.

United States to tighten controls on narcotic painkillers

United States to tighten controls on narcotic painkillers

The U.S. Drug Enforcement Administration (DEA) to enact tough new controls on painkillers containing hydrocodone, which has been tied to a surge in addictions across the United States.

Surgery for advanced laryngeal cancer provides survival benefit

Surgery for advanced laryngeal cancer provides survival benefit

A small but significant advantage in disease-specific, overall survival, is seen for patients with advanced laryngeal cancer, even after adjustment.

Endogenous hormones improve breast cancer risk prediction

Endogenous hormones improve breast cancer risk prediction

Inclusion of endogenous hormones in prediction models improves prediction of invasive breast cancer risk in postmenopausal women, according to a study.

Bisphosphonate use may not prevent breast cancer

Bisphosphonate use may not prevent breast cancer

Data from two randomized controlled trials suggest that bisphosphonate use does not protect against postmenopausal breast cancer, according to research.

Patients with Medicaid or no coverage show higher cancer mortality

Patients with Medicaid or no coverage show higher cancer mortality

Patients with Medicaid insurance or no insurance coverage are less likely to receive cancer-related surgery and/or radiation and are more likely to die from cancer than those with insurance, according to an online study.

Once-only flexible sigmoidoscopy screening lowers colorectal cancer incidence

Once-only flexible sigmoidoscopy screening lowers colorectal cancer incidence

Once-only flexible sigmoidoscopy screening, with or without fecal occult blood testing (FOBT), is associated with reduced colorectal cancer incidence and mortality, according to a study.

CDC breast and cervical cancer screening program benefits millions

CDC breast and cervical cancer screening program benefits millions

Millions of American women have benefited from a breast and cervical cancer screening program offered by the U.S. Centers for Disease Control and Prevention (CDC), according to a new report.

Unrecognized lung cancer trends identified

Unrecognized lung cancer trends identified

An updated and expanded analysis has revealed some new observations about patterns in lung cancer incidence in the United States, according to research.

New mutations may increase breast cancer risk

New mutations may increase breast cancer risk

Mutations in PALB2 and germline mutations in the multiple endocrine neoplasia type 1 (MEN1) tumor-suppressor gene causing MEN1 correlate with increased breast cancer risk, according to two studies.

Herpes zoster vaccine effective with chemotherapy

Herpes zoster vaccine effective with chemotherapy

Vaccine is effective even among older adults who subsequently undergo chemotherapy.

Lasting drop in prostate cancer mortality with prostate-specific antigen (PSA)

Lasting drop in prostate cancer mortality with prostate-specific antigen (PSA)

Prostate-specific antigen (PSA) screening is associated with a lasting reduction in prostate cancer mortality, according to a study published online.

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