AACR: Metformin benefit not seen in pancreatic ductal cancer

AACR: Metformin Benefit Lacking in Pancreatic Ductal CA
AACR: Metformin Benefit Lacking in Pancreatic Ductal CA

(HealthDay News) -- Despite evidence that has suggested metformin might have potential in cancer, a new study finds the medication doesn't help patients with pancreatic ductal adenocarcinoma (PDAC). The study was to be presented Tuesday at the annual meeting of the American Association for Cancer Research, held from April 18 to 22 in Philadelphia.

In the retrospective study, researchers examined the medical records of 1,360 patients with PDAC, some of whom took metformin.

Patients with PDAC who took the drug didn't gain any survival benefit from the medication, the researchers said. The median number of survival days for those who didn't take the drug was 308 days, compared to 292 days for those who did.

"Studies of medication exposure and cancer survival warrant very careful and detailed data collection, which is not always possible in a retrospective study design," study author Roongruedee Chaiteerakij, M.D., Ph.D., of the Division of Gastroenterology and Hepatology at the Mayo Clinic Cancer Center in Rochester, Minn., said in a news release from the American Association for Cancer Research. "Researchers should exercise caution when initiating clinical trials based on retrospective epidemiologic studies."

Press Release
More Information

Loading links....
You must be a registered member of ONA to post a comment.

Sign Up for Free e-newsletters

Regimen and Drug Listings


Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs