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Gender Bias in Medicine Has Far-Reaching Consequences

Gender Bias in Medicine Has Far-Reaching Consequences

Exclusion of women from upper echelons of medicine may have real implications for patient care.

Carfilzomib Benefits May Outweigh Cardiovascular Risk in Multiple Myeloma

Carfilzomib Benefits May Outweigh Cardiovascular Risk in Multiple Myeloma

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In an analysis of 11 studies, researchers investigated whether the benefits of carfilzomib for multiple myeloma outweigh the cardiovascular risks. However, the researchers recommend careful monitoring and management of blood pressure and volume status as good clinical practice, regardless.

Patient Interest in Melanoma Genetic Risk Testing is Fairly High

Patient Interest in Melanoma Genetic Risk Testing is Fairly High

Researchers examined interest in MC1R testing in the general population and assessed patterns across demographic and skin cancer risk factors.

Genetic Link Between Depression and Breast Cancer Remains Unclear

Genetic Link Between Depression and Breast Cancer Remains Unclear

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In this study, researchers sought to determine if a genetic predisposition to depression exists in some patients with breast cancer and how to identify it.

Bariatric Surgery Reduced Risk of Some Cancers in Obese Patients

Bariatric Surgery Reduced Risk of Some Cancers in Obese Patients

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Weight loss associated with bariatric surgery could reduce risk of hormone-related cancers, but an increased risk for colorectal cancer was seen in patients who underwent gastric bypass.

Informational Studies About Medical Marijuana Are Lacking

Informational Studies About Medical Marijuana Are Lacking

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Researchers surveyed random sample of 400 oncologists to asses their views and practices with medical marijuana.

Guideline Recommendations Offer No OS Benefit for Younger Patients With Rectal Cancer

Guideline Recommendations Offer No OS Benefit for Younger Patients With Rectal Cancer

A retrospective review of data from the National Cancer Data Base demonstrated that trends in rectal cancer may follow a pattern similar to that of colon cancer.

Study Finds Association Between Folate Intake and Risk of Cutaneous Melanoma

Study Finds Association Between Folate Intake and Risk of Cutaneous Melanoma

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Researchers assessed the effect intake levels of folate and other nutrients involved in one-carbon metabolism have on risk of melanoma.

Certain Risk Factors May Decrease Overall Survival in Pediatric B-NHL

Certain Risk Factors May Decrease Overall Survival in Pediatric B-NHL

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A new analysis of FAB/LMB 96 looked into factors associated with shortened OS among children and adolescents with B-NHL.

Encorafenib, Binimetinib Combination Receives FDA Approval for Mutation-Positive Melanoma

Encorafenib, Binimetinib Combination Receives FDA Approval for Mutation-Positive Melanoma

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Approval was granted for the treatment of patients with unresectable or metastatic BRAF V600E or V600K mutation-positive melanoma.

Radiation, Immunotherapy Improved Median Overall Survival in Melanoma Brain Metastases

Radiation, Immunotherapy Improved Median Overall Survival in Melanoma Brain Metastases

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Study data indicate that checkpoint inhibitors combined with radiation could improve survival for patients with melanoma-related brain metastases.

Involved-Field Radiotherapy Plus Chemotherapy Prolonged PFS in Follicular Lymphoma

Involved-Field Radiotherapy Plus Chemotherapy Prolonged PFS in Follicular Lymphoma

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Although involved-field radiotherapy (IFRT) has a high level of disease control in patients with follicular lymphoma, relapse frequently occurs; therefore, researchers sought to determine if adding chemotherapy would improve progression-free survival.

New Guidelines Increase Melanoma Staging Reproducibility and Concordance

New Guidelines Increase Melanoma Staging Reproducibility and Concordance

Greater reproducibility and higher concordance for melanoma staging observed with implementation of AJCC 8.

Qualitative Analysis of Myeloma Patients' Experience Following Hematopoietic Stem Cell Transplant

Qualitative Analysis of Myeloma Patients' Experience Following Hematopoietic Stem Cell Transplant

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In this study, researchers investigated the effects of exercise on physical and psychological recovery after autoHSCT for multiple myeloma.

Effective NP-Physician Comanagement Found to Depend on 3 Vital Attributes

Effective NP-Physician Comanagement Found to Depend on 3 Vital Attributes

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Researchers employed a literature search and in-person qualitative interviews to determine the key elements to successful NP-physician comanagement.

Data on Corticosteroid-Related Adverse Events in Advanced Cancer Are Lacking, Needed

Data on Corticosteroid-Related Adverse Events in Advanced Cancer Are Lacking, Needed

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Although corticosteroids are frequently used to manage adverse effects (AEs), data on AEs related to these agents are lacking. Therefore, these researchers sought to determine if better reporting of corticosteroid-related AEs would be of benefit.

Chinese Traditional Medicine Showed Effectiveness on Pain, Quality of Life in Advanced Cancer

Chinese Traditional Medicine Showed Effectiveness on Pain, Quality of Life in Advanced Cancer

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In a randomized study, researchers sought to determine the effect of IV injections of coix seed oil, a Chinese CAM, on pain and quality of life measures for patients with advanced cancer.

Handgrip Force May Provide Objective Evaluation of Cancer-Related Fatigue

Handgrip Force May Provide Objective Evaluation of Cancer-Related Fatigue

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Researchers sought to determine if handgrip force could provide objective measures of CRF in patients with cancer.

CALM: A Depression Intervention for Cancer Patients at the End of Life

CALM: A Depression Intervention for Cancer Patients at the End of Life

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The effectiveness of a novel intervention intended to reduce and/or prevent depression in patients with advanced cancer at the end of life was investigated in a randomized study with more than 300 patients.

Higher Cancer Rates Confirmed in Women With Dense Breasts

Higher Cancer Rates Confirmed in Women With Dense Breasts

Higher rate of recall, lower sensitivity, larger tumor diameter, and more lymph node-positive disease observed in women with dense breasts.

Does a Diagnosis of Solid Tumor Prohibit Postsurgical ICU Admissions?

Does a Diagnosis of Solid Tumor Prohibit Postsurgical ICU Admissions?

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Using a comparator group, researchers sought to determine the impact of a diagnosis of solid tumor on outcomes among postsurgical ICU admissions in patients with cancer vs those without cancer.

Live or Online Mindfulness-Based Cognitive Therapy Reduced Cancer-Related Psychological Distress

Live or Online Mindfulness-Based Cognitive Therapy Reduced Cancer-Related Psychological Distress

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Mindfulness-based interventions are proven effective in helping patients with cancer manage distress and other psychological symptoms. In this study, researchers sought to determine if Internet-based MBCT can be as effective as face-to-face interventions.

PTSD May Increase Symptom Burden in Patients With Cancer

PTSD May Increase Symptom Burden in Patients With Cancer

Post-traumatic stress symptoms are linked to a greater symptom burden in hospitalized cancer patients.

Managing Dyspnea With Fentanyl in Patients With Cancer at End of Life

Managing Dyspnea With Fentanyl in Patients With Cancer at End of Life

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In this retrospective study, researchers sought to determine the effectiveness of fentanyl for dyspnea in dying patients with advanced cancer.

Remission Duration Predicts Long-Term Outcomes in Chronic Lymphocytic Leukemia

Remission Duration Predicts Long-Term Outcomes in Chronic Lymphocytic Leukemia

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A retrospective study sought to evaluate outcomes for patients with CLL who were treated with FCR, a highly effective treatment, and initially had refractory disease, experienced relapse early, or were unable to complete therapy due to toxicity.

Nonresearch Physician Compensation Linked to Opioid Prescription Rates

Nonresearch Physician Compensation Linked to Opioid Prescription Rates

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Researchers examine the possible impact that opioid products marketed by the pharmaceutical industry may have on clinician prescribing rates.

Malnutrition, Decreased QOL Possible After Radiation Therapy for Head and Neck Cancer

Malnutrition, Decreased QOL Possible After Radiation Therapy for Head and Neck Cancer

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In a retrospective study, researchers used established tools to measure the nutritional status of patients with head and neck cancer before, immediately after, and at 2 follow-up points after radiotherapy.

High BMI Among Premenopausal Women May Improve Risk for Breast Cancer

High BMI Among Premenopausal Women May Improve Risk for Breast Cancer

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Researchers report on a study to determine the relationship between BMI and risk for breast cancer among younger women, particularly those 18 to 24 years old.

Ixazomib, Lenalidomide, Dexamethasone Effective But Increases Toxicity in Multiple Myeloma

Ixazomib, Lenalidomide, Dexamethasone Effective But Increases Toxicity in Multiple Myeloma

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Three-drug regimen twice a week achieved good response and long-term outcomes in patients with newly diagnosed multiple myeloma; however, regimen has higher toxicity than once weekly dose.

Interim Data Shows Romiplostim May Lead to Positive Long-Term Response in Pediatric ITP

Interim Data Shows Romiplostim May Lead to Positive Long-Term Response in Pediatric ITP

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In a poster presentation at the 23rd Congress of EHA, researchers described a study of the efficacy of romiplastim in achieving a platelet response in pediatric patients with immune thrombocytopenia.

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