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Should Increased Breast Density Dictate More Breast Cancer Screenings?

Should Increased Breast Density Dictate More Breast Cancer Screenings?

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Pros and cons of increased breast cancer screening in women with dense breasts are presented by experts.

Eighth AJCC TNM Staging Equalizes Distribution, Improves Prognostics of Pancreatic Cancer Stages

Eighth AJCC TNM Staging Equalizes Distribution, Improves Prognostics of Pancreatic Cancer Stages

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In a comparison study with the seventh edition, updates in the eighth edition of the American Joint Committee on Cancer TNM staging resulted in a more equalized distribution across stages and modestly increased prognostic accuracy for nonmetastatic pancreatic ductal adenocarcinoma.

Smoking Ups Risk of Myeloproliferative Neoplasms Overall and by Subtype

Smoking Ups Risk of Myeloproliferative Neoplasms Overall and by Subtype

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In a review of data from DANHES study, researchers determined the hazard ratio for developing myeloproliferative neoplasm — any or by subtype — among smokers, occasional smokers, and ex-smokers, compared with never smokers.

Use of Corticosteroids With PD-1 or PD-L1 Inhibitors Associated With Poorer Outcomes in NSCLC

Use of Corticosteroids With PD-1 or PD-L1 Inhibitors Associated With Poorer Outcomes in NSCLC

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A retrospective study of patients with NSCLC from 2 cancer centers demonstrates that concurrent use of corticosteroids with PD-1 or PD-L1 inhibitors at baseline decreases progression-free and overall survival for these patients.

NHS, HPFS Show Regular Aspirin Use Reduced Hepatocellular Carcinoma Risk

NHS, HPFS Show Regular Aspirin Use Reduced Hepatocellular Carcinoma Risk

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An analysis of results from the NHS and the HPFS showed that regular use of aspirin — standard-dose 325-mg tablets — reduced hepacellular carcinoma in a dose-dependent manner.

HPV Vaccination and Anti-programmed Cell Death 1 Inhibition Improve Survival in Patients With Invasive HPV-16

HPV Vaccination and Anti-programmed Cell Death 1 Inhibition Improve Survival in Patients With Invasive HPV-16

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In this study, researchers sought to determine if use of a tumor specific vaccine would improve the efficacy of PD-1 immune checkpoint inhibition in patients with incurable HPV-16 cancer.

FDA Approves HPV Vaccine for People Through Age 45

FDA Approves HPV Vaccine for People Through Age 45

Updated vaccine designed to prevent cancers and disease caused by nine HPV types

Weight Loss May Cut Breast Cancer Risk in Postmenopausal Women

Weight Loss May Cut Breast Cancer Risk in Postmenopausal Women

Researchers have linked weight loss with a lower risk of breast cancer in postmenopausal women.

LDR-BT Boost Plus EBRT, ADT Improves Survival in High-Risk Prostate Cancer

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Low-dose-rate brachytherapy, as an addition to radiation therapy and ADT, helps improve survival in high-risk prostate cancer, according to new study data.

Early Checkpoint Inhibition With Cytotoxic Chemotherapy Improves OS, PFS in Extensive-Stage SCLC

Early Checkpoint Inhibition With Cytotoxic Chemotherapy Improves OS, PFS in Extensive-Stage SCLC

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In this randomized, double-blind, placebo-controlled study, researchers sought to determine the effect of including a checkpoint inhibitor in induction therapy for patients with extensive-stage small cell lung cancer.

Aggressive EOL Care Negatively Impacts Care Quality, Health Costs in Metastatic Lung Cancer

Aggressive EOL Care Negatively Impacts Care Quality, Health Costs in Metastatic Lung Cancer

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Researchers determined that aggressive care at the end of life (EOL) leads to diminished quality of life, poor quality of care, and increased costs for patients with advanced lung cancer.

Frequency of Reclassifications of Genetic Testing Results Is Low

Frequency of Reclassifications of Genetic Testing Results Is Low

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A retrospective analysis of genetic testing results at one laboratory reports that reclassifications occurs in approximately one-quarter of tests, resulting in both downgrades and upgrades of variant classifications.

Delphi Panel Presents Recommendations for Expanding Role of Patients in Research

Delphi Panel Presents Recommendations for Expanding Role of Patients in Research

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A Delphi panel developed recommendations for integrating patients, as well as caregivers and advocate, a greater role in medical research while maintaining scientific integrity of studies.

Second Opinions from Multidisciplinary Breast Tumor Board Are Beneficial

Second Opinions from Multidisciplinary Breast Tumor Board Are Beneficial

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A retrospective, observational study investigated the impact of obtaining a second opinion of a breast cancer diagnosis from a multidisciplinary tumor board.

Delayed Administration Device for Pegfilgratim Safe, Effective in Preventing Grade 4 Neutropenia

Delayed Administration Device for Pegfilgratim Safe, Effective in Preventing Grade 4 Neutropenia

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In a comparison study, the Onpro® device was found to be a safe and effective alternative to manual injection of pegfilgrastim in patients receiving chemotherapy.

Self-Care Toolkits Ease Negative PostSurgery Experiences for Patients With Breast Cancer

Self-Care Toolkits Ease Negative PostSurgery Experiences for Patients With Breast Cancer

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Self-care toolkits were found to reduce pain and other negative postsurgical experiences for women undergoing surgical procedures for breast cancer.

Influence of Surgical Options for Early-Stage Lung Cancer on Opioid Use

Influence of Surgical Options for Early-Stage Lung Cancer on Opioid Use

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A research letter presents results of a study on opioid use among patients in the SEER database who underwent open resection vs VATS for non-small cell lung cancer.

Number of Health-Related Data Breaches on the Increase

Number of Health-Related Data Breaches on the Increase

The researchers found that individual breaches affected a range of 500 to 78.8 million records.

Risk of Relapse Up for Young Adults With Leukemia

Risk of Relapse Up for Young Adults With Leukemia

Increased risk of on-therapy relapse, relapse after completing therapy versus children with ALL

Discussing Treatment Costs Reduces Risk of Financial Harm for Patients With Breast Cancer

Discussing Treatment Costs Reduces Risk of Financial Harm for Patients With Breast Cancer

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Results of an electronic survey of women with a history of stage 0-III breast cancer revealed patients' preferences for including costs when discussing treatment options with their cancer care team.

Maintaining High Level of Activity Has Inverse Relationship With Prostate Cancer Risk

Maintaining High Level of Activity Has Inverse Relationship With Prostate Cancer Risk

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Men who have physically demanding jobs may have a lower risk of prostate cancer than those who do not, according to study data.

Implementing OCM Practices to Improve ED Visits, Hospitalizations, Inpatient Costs

Implementing OCM Practices to Improve ED Visits, Hospitalizations, Inpatient Costs

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A team from Oncology Hematology Care, in Cincinnati, Ohio, presented an outcomes report on their Oncology Care Model project at the 2018 ASCO Quality Care Symposium.

Belly Fat Is a Better Risk Calculator for Blood Cancers Than BMI

Belly Fat Is a Better Risk Calculator for Blood Cancers Than BMI

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BMI often relies on self-reported weight and height values, and therefore may be a less accurate predictor of cancer risk than alternative body composition measurements.

Opioid Overdose Statistics Among Cancer Population Is Different From General Population

Opioid Overdose Statistics Among Cancer Population Is Different From General Population

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Researchers sought to determine the incidence and demographic factors of patients with cancer whose deaths were attributed to opioid overdose over a 10-year period.

Nonopioid Pain Medications Found to Control Postop Pain, Reduce Anxiety Effectively

Nonopioid Pain Medications Found to Control Postop Pain, Reduce Anxiety Effectively

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Researchers presented results of a project designed to reduce opioid use while effectively managing pain and anxiety in patients who had undergone surgery for urologic cancer at the 2018 ASCO Quality Care Symposium.

Lack of Choice Perceived Among Those Treated With RAI for Differentiated Thyroid Cancer

Lack of Choice Perceived Among Those Treated With RAI for Differentiated Thyroid Cancer

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Results of a population-based survey, presented at the 2018 ASCO Quality Care Symposium, revealed patients' perceptions regarding choice of treatment of differentiated thyroid cancer (DTC).

Promising New Way to Identify Breast Cancer Tumors

Promising New Way to Identify Breast Cancer Tumors

An examination of the parameters of a cell's nucleus can help identify the molecular markers of breast cancer tumors.

Novel Immunotherapy May Increase Survival in Melanoma Brain Metastases

Novel Immunotherapy May Increase Survival in Melanoma Brain Metastases

Researchers used data from the National Cancer Database to evaluate the overall survival of patients who presented with cutaneous MBM from 2010 to 2015.

Integrating Mental Health Into Multidisciplinary Oncology Care Improves Inpatient Care

Integrating Mental Health Into Multidisciplinary Oncology Care Improves Inpatient Care

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In a study presented at the 2018 ASCO Quality Care Symposium, researchers presented study findings that showed adding mental health professionals to the multidisciplinary cancer care team improves identification and treatment of delirium in hospitalized patients.

CNS Tumors in Childhood: Predicting Successful Independence in Adult Life

CNS Tumors in Childhood: Predicting Successful Independence in Adult Life

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Researchers at St Jude Children's Research Hospital sought to determine what indicators in survivors of CNS tumors can predict the survivor's ability to live independently as an adult.

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