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Redefining Prognosis for Hematologic Cancers in Older Adults by Age

Redefining Prognosis for Hematologic Cancers in Older Adults by Age

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A report on how variations in the effects of geriatric syndromes and aging can affect treatment modality choices and outcomes for the eldest older adults with hematologic cancers.

Outcomes for Elderly With Hematologic Cancers Effected by Cognitive Impairments

Outcomes for Elderly With Hematologic Cancers Effected by Cognitive Impairments

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Study data suggest that cognitive impairments may be associate with worse survival among patients with hematologic cancer.

FDA Approves Fostamatinib for ITP After Insufficient Response to Previous Treatment

FDA Approves Fostamatinib for ITP After Insufficient Response to Previous Treatment

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The US FDA granted approval to fostamatinib (Tavalisse), a kinase inhibitor, for the treatment of thrombocytopenia in patients with chronic IPT who have had an insufficient response to a previous treatment.

Elderly Patients Are Underrepresented in Trials For Soft Tissue Sarcoma

Elderly Patients Are Underrepresented in Trials For Soft Tissue Sarcoma

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With median age of participants in clinical trials for soft-tissue sarcoma younger than most patients who develop the disease, these researchers sought to determine the prevalence of including persons older than 65 in clinical trials and the efficacy of first-line chemotherapy for STS in older patients.

Combination Effective as First-Line Therapy in Advanced ER-Positive HER2-Negative Breast Cancer

Combination Effective as First-Line Therapy in Advanced ER-Positive HER2-Negative Breast Cancer

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In this open label phase 2 BOLERO-4 study, researchers evaluated the effect of everolimus plus endocrine therapy on progression-free survival.

In Older Women With Breast Cancer QoL May Predict 10-Year Mortality

In Older Women With Breast Cancer QoL May Predict 10-Year Mortality

A model that incorporates HRQOL was found to outperform a model that only employs traditional prognostic variables.

Progression-Free Survival Extended With PANEX Protocol in R/R Multiple Myeloma

Progression-Free Survival Extended With PANEX Protocol in R/R Multiple Myeloma

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This treatment-expansion study evaluated the tolerability and safety of the PANEX (panobinostat plus bortezomib with dexamethasone) protocol in heavily treated patients with R/R multiple myeloma.

Screening Colonoscopy Improves CRC-Related Mortality in Veterans

Screening Colonoscopy Improves CRC-Related Mortality in Veterans

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Researchers conducted a case-control study to determine whether colonoscopy is associated with decreased CRC mortality in veterans and whether its effect differs by anatomical location of CRC.

National Cancer Drug Shortages Unknown to Many Patients

National Cancer Drug Shortages Unknown to Many Patients

A majority of study respondents reported wanting to be informed about the differences in a drug substitution's efficacy or side effects.

Physical Inactivity Linked With Increased Risk of Hodgkin, Non-Hodgkin Lymphoma

Physical Inactivity Linked With Increased Risk of Hodgkin, Non-Hodgkin Lymphoma

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In a case-control study using PEDS data, researchers determined the impact of inactivity on risk for Hodgkin lymphoma and non-Hodgkin lymphoma.

Following ACS Guidelines Shown to Improve Outcomes for Colon Cancer Survivors

Following ACS Guidelines Shown to Improve Outcomes for Colon Cancer Survivors

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A prospective study assessing the outcomes of a cohort of participants in the CALGB 89803 study determined the effect of following the American Cancer Society guidelines on survival for persons with colon cancer.

Intratumor Rotavirus Therapy Has Potential to Overcome Immunotherapy Resistance

Intratumor Rotavirus Therapy Has Potential to Overcome Immunotherapy Resistance

In immunocompetent murine models of lymphoma and neuroblastoma, IT rotavirus therapy demonstrated that it can overcome immune checkpoint inhibitor resistance.

Pivot Nurse Improves Patients' Navigation Through Lung Cancer Care

Pivot Nurse Improves Patients' Navigation Through Lung Cancer Care

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Researchers in Montreal presented results of a study on the effects of using a pivot nurse in oncology (PNO) on continuity of care, outcomes, and quality of life for patients with lung cancer at the 2018 European Lung Cancer Congress.

Tobacco Use Data Supports Efforts to Reduce Burden of Smoking-Associated Cancers

Tobacco Use Data Supports Efforts to Reduce Burden of Smoking-Associated Cancers

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Analysis of data from more than 1 million people demonstrates the value of tobacco-use data in tailoring public health programs to prevalence of smokers in local populations.

Factoring in Breast Density Improves Long-Term Risk Models for Breast Cancer

Factoring in Breast Density Improves Long-Term Risk Models for Breast Cancer

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A study using a cohort of women from Kaiser Permanente Washington evaluated the accuracy of risk assessment models for breast cancer that included classic risk factors with and without breast density as an additional factor during more than 10 years of follow-up.

Heart-Specific Mortality Not Higher Among Breast Cancer Survivors

Heart-Specific Mortality Not Higher Among Breast Cancer Survivors

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A retrospective cohort study of data from the SEER database assessed the potential risk of cardiac-related mortality in patients with breast cancer, treated with chemotherapy or radiotherapy, vs the general population.

Nursing Students Not Always Correctly Identifying Some Patient Care Needs

Nursing Students Not Always Correctly Identifying Some Patient Care Needs

Students better at identifying physical care needs, less so psychosocial, relational needs

Palpable Cancers Detected at Smaller Size in Breasts With Implants

Palpable Cancers Detected at Smaller Size in Breasts With Implants

Researchers reviewed 48 cases of patients with prior breast augmentation undergoing breast cancer treatment to determine detection rate and treatment choices.

Individuals With Alcohol-Related Hepatocellular Carcinoma Have Reduced OS

Individuals With Alcohol-Related Hepatocellular Carcinoma Have Reduced OS

Patients with alcohol-related HCC displayed reduced OS when compared to patients with non-alcohol-related HCC.

Vaping May Induce Severe, Negative Effects on Lung Health

Vaping May Induce Severe, Negative Effects on Lung Health

Researchers presented the preliminary results from an ongoing randomized, crossover study evaluating the cardiorespiratory effects of e-cigarettes.

1-year Imatinib or Nilotinib Therapy Not Associated with Cardiotoxity in CML

1-year Imatinib or Nilotinib Therapy Not Associated with Cardiotoxity in CML

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Although many TKIs have well-documented cardiotoxic effects, results of a single-center prospective study that assessed effects of 1 year of therapy with imatinib or nilotinib in patients with CML demonstrated safety and efficacy of the 2 agents in this population.

Risk of Secondary Cancers With CML Linked to Disease, Not Treatment

Risk of Secondary Cancers With CML Linked to Disease, Not Treatment

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This study examined the risk of secondary cancers among patients with CML who were treated with TKIs.

Long-term Carfilzomib May Be Safe, Effective In Relapsed Multiple Myeloma

Long-term Carfilzomib May Be Safe, Effective In Relapsed Multiple Myeloma

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In a post-hoc analysis of the ASPIRE trial results, in which carfilzomib was discontinued due to a lack of long-term safety data, researchers present the safety and efficacy findings of KRd vs Rd for relapsed multiple myeloma at 18 months from randomization.

Include Visual Emphysema, COPD Exacerbations When Assessing for Lung Cancer 

Include Visual Emphysema, COPD Exacerbations When Assessing for Lung Cancer 

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Researchers conducted a case-control study that examined independent predictive factors of lung cancer in patients with chronic obstructive pulmonary disease.

Benefit of Lymph Node Biopsies May Be Limited in Microinvasive Breast Cancer

Benefit of Lymph Node Biopsies May Be Limited in Microinvasive Breast Cancer

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Researchers sought to determine the benefit of managing microinvasive breast cancer similarly to invasive tumors in a retrospective study.

CHEST Panel Updates Criteria for Low-Dose CT Screening for Lung Cancer

CHEST Panel Updates Criteria for Low-Dose CT Screening for Lung Cancer

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The panel assembled and updated the above guidelines and recommendations regarding lung cancer screening and low-dose CT screening programs.

Relative Visceral Fat Area an Indicator of Mortality Risk for Women With RCC

Relative Visceral Fat Area an Indicator of Mortality Risk for Women With RCC

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An evaluation of patients with clear cell renal cell carcinoma revealed greater risk of death for female patients with high relative visceral fat area (rVFA), highlighting the significance of metabolic differences between men and women.

Prognostic Indicator for Cutaneous Melanoma: SNLB vs Breslow Thickness

Prognostic Indicator for Cutaneous Melanoma: SNLB vs Breslow Thickness

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Investigators sought to compare the prognostic value of sentinel lymph node status vs Breslow thickness in patients with cutaneous melanoma.

SEE-ACBT Method Improves Postsurgical Outcomes in Lung Cancer Resection

SEE-ACBT Method Improves Postsurgical Outcomes in Lung Cancer Resection

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In a quasi-experimental pre-post study, researchers demonstrate the efficacy of the SEE-ACBT rehabilitation method on health-related and cost outcomes in patients with NSCLC who underwent curative lung resection.

Improved Access to Care Reported by Cancer Survivors

Improved Access to Care Reported by Cancer Survivors

In the 2010 to 2016 period, the proportion of survivors reporting delayed medical care decreased yearly.

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