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Daily Aspirin Reduced Risk of HBV-Related Hepatocellular Carcinoma

Daily Aspirin Reduced Risk of HBV-Related Hepatocellular Carcinoma

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Study presented at the AASLD The Liver Meeting 2017 demonstrated the effect of regular aspirin use on risk of hepatocellular carcinoma in patients with chronic HBV.

Lanreotide Effectively Controls Diarrhea, Flushing in Neuroendocrine Tumors

Lanreotide Effectively Controls Diarrhea, Flushing in Neuroendocrine Tumors

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Results of the double-blinded and initial open-label phases of the ELECT Study demonstrate the effectiveness of lanreotide in controlling diarrhea and flushing in patients with NETs presenting with carcinoid syndrome.

Novel Predictive Model More Effectively Identifies Risk for Lung Cancer

Novel Predictive Model More Effectively Identifies Risk for Lung Cancer

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PanCan study results demonstrate the effectiveness of a novel predictive model in identifying risk of lung cancer in patients who do not meet the screening criteria of other models, including those used in the NLST.

Long-Term Eltrombopag Increases Platelet Counts, Decreases Bleeding in ITP

Long-Term Eltrombopag Increases Platelet Counts, Decreases Bleeding in ITP

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Previous studies determined the effectiveness of 6 months of therapy with eltrombopag in patients with ITP. In this analysis, researchers extended 4 clinical trials to assess efficacy and safety of eltrombopag therapy for more than 6 months in patients with ITP.

Overall Survival Increase for Melanoma Brain Metastases

Overall Survival Increase for Melanoma Brain Metastases

Median overall survival from time of diagnosis has increased from 7.5 to 22.7 months

Prophylactic Prochloperazine Ineffective for Opioid-induced Nausea/Vomiting in Cancer

Prophylactic Prochloperazine Ineffective for Opioid-induced Nausea/Vomiting in Cancer

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A randomized study was conducted to determine the efficacy of prophylactic prochlorperazine in reducing opioid-induced nausea and vomiting in patients with cancer receiving opioids for pain management.

Increase in Rate of Breast Reconstruction for Mastectomy

Increase in Rate of Breast Reconstruction for Mastectomy

From 2009 to 2014, increases for all age groups, especially for women aged 65 years and older

Neurotoxicity After CAR T-cell Therapy May Be Associated With Endothelial Activation

Neurotoxicity After CAR T-cell Therapy May Be Associated With Endothelial Activation

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Despite its high response rate, researchers are finding that patients with endothelial activation prior to lymphodepletion chemotherapy are at greater risk of neurologic adverse events after undergoing CAR T-cell therapy for relapsed/refractory B-ALL, CLL, or NHL.

Prosthetic Nipple Crowns Survivor's Quest for Improved Breast Reconstruction

Prosthetic Nipple Crowns Survivor's Quest for Improved Breast Reconstruction

When her search for a realistic nipple to complete her breast reconstruction alluded Michelle Kolath-Arbel, a breast cancer survivor, she decided to make one herself.

Navigation Programs Most Effective in Increasing Follow-up Colonoscopy

Navigation Programs Most Effective in Increasing Follow-up Colonoscopy

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An analysis of 23 studies focused on interventions with the potential to improve follow-up colonoscopy completion rates found that navigation programs are more effective than other interventions studied.

Nivolumab Provides Better Long-Term Efficacy Compared With Docetaxel in NSCLC

Nivolumab Provides Better Long-Term Efficacy Compared With Docetaxel in NSCLC

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Two phase 3 studies reveal the clinical benefit, safety profile, and overall survival of nivolumab and docetaxel for patients with squamous and nonsquamous NSCLC.

Specialized Interventions Reduce Aberrant Opioid Behaviors in Cancer Patients

Specialized Interventions Reduce Aberrant Opioid Behaviors in Cancer Patients

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Investigators the effectiveness of an intervention to reduce aberrant opioid-related behavior and use of opioids in patients with cancer receiving chronic opioid therapy.

All-Cause Mortality Improved by Advances in Radiotherapy for Hodgkin Lymphoma

All-Cause Mortality Improved by Advances in Radiotherapy for Hodgkin Lymphoma

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Investigators assessed the impact of advances over time in the treatment of Hodgkin lymphoma on all-cause mortality in patients with Hodgkin lymphoma who received radiotherapy alone or with chemotherapy.

Defibrotide an Effective Option for SOS/VOD in Patients Undergoing HSCT

Defibrotide an Effective Option for SOS/VOD in Patients Undergoing HSCT

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Sinusoidal obstruction syndrome (or hepatic veno-occlusive disease), a complication observed in patients who undergo HSCT, is managed with defibrotide. In this study, investigators assessed its efficacy and patient response to therapy.

New Tool Identifies Mortality Risk After Bladder Cancer Surgery

New Tool Identifies Mortality Risk After Bladder Cancer Surgery

Tool incorporates the relative contribution of tumor stage and lymph node involvement.

Nurse Survey Identifies Adverse Events Related to Handling Chemotherapy

Nurse Survey Identifies Adverse Events Related to Handling Chemotherapy

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Using a 4-question survey, investigators determined oncology nurses' perception of their risks in handling and administering cytotoxic chemotherapy to patients.

Negative Margins, Lymph Node Yields Predict Survival

Negative Margins, Lymph Node Yields Predict Survival

Patients with head and neck cancer treated at hospitals attaining the combined metric of a 90 percent or higher negative margin rate and 80% percent of cases achieving a LNY of 18 or more experienced a significant reduction in mortality.

Disruptions to Circadian Rhythm Linked to Prostate Cancer Surgery Regret

Disruptions to Circadian Rhythm Linked to Prostate Cancer Surgery Regret

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A survey followed up with an assessment via validated tools determined that patients with prostate cancer who experienced regret after radical prostatectomy were more susceptible to depression-associated sleep disorders.

High Rates of Adverse Events Lead to Earlier Dropouts in Phase 1 Cancer Trials

High Rates of Adverse Events Lead to Earlier Dropouts in Phase 1 Cancer Trials

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Phase 1 trials are used to determine the safety profiles of treatment regimens. In this retrospective review, investigators sought to understand the reasons participants in these studies drop out.

Rate of Obesity-Related Cancers High in the United States

Rate of Obesity-Related Cancers High in the United States

Approximately 40 percent of cancer diagnoses in the U.S. are tied to extra weight; rate higher in older individuals, females.

Symptoms, Economic Burden Reduce QoL in Gastrointestinal Cancer Survivors

Symptoms, Economic Burden Reduce QoL in Gastrointestinal Cancer Survivors

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A cross-sectional survey revealed the impact of symptoms and economic burden on quality of life for survivors of gastrointestinal cancer.

Study Examines Role of MicroRNA in Tumor Growth

Study Examines Role of MicroRNA in Tumor Growth

A study examines the role of two hypoxia-responsive microRNAs, miR-25 and miR-93, in establishing an immunosuppressive tumour microenvironment.

Surveillance Plus FIT for CRC Screening: Additional Costs Not Justified by Benefits

Surveillance Plus FIT for CRC Screening: Additional Costs Not Justified by Benefits

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Investigators sought to determine clinical and cost effectiveness of additional colonoscopy screening in patients undergoing FIT screening for colorectal cancer.

Naldemedine Effective for Opioid-Induced Constipation in Cancer Pain

Naldemedine Effective for Opioid-Induced Constipation in Cancer Pain

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Opioids are an effective option for managing cancer pain; however, opioid-induced constipation (OIC) detracts from their effectiveness. In this study, investigators sought to determine if naldemedine use improved OIC without reducing pain relief.

DVD Motivated Patients to Exercise for Managing Fatigue in Breast Cancer

DVD Motivated Patients to Exercise for Managing Fatigue in Breast Cancer

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Patients with breast cancer experiencing fatigue need to be encouraged to exercise. In this study, investigators measured the impact of enhancing oncologist recommendations with a yoga-based DVD.

A Case of Newly Diagnosed PCV After Relapse TTP Complicated by Undiagnosed RA

A Case of Newly Diagnosed PCV After Relapse TTP Complicated by Undiagnosed RA

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This case of a 63-year-old African American male with a complicated history illustrates the need for a comprehensive risk assessment of thrombosis in patients with primary polycythemia vera, especially those with concomitant conditions that predispose to thrombosis.

Anticancer Properties of The Probiotic Kefir: A Review

Anticancer Properties of The Probiotic Kefir: A Review

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A review of data on kefir has shown that the probiotic milk drink has potential anticancer properties affecting apoptosis, proliferation, and the anti-oxidative process in several cancers, including breast or gastric cancer, leukemia, and sarcoma.

A Rare Case of Simultaneous Second Malignancies in Relapsed Multiple Myeloma

A Rare Case of Simultaneous Second Malignancies in Relapsed Multiple Myeloma

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A first-reported case of simultaneous intracranial plasmacytoma and malignant pericardial effusion in a woman with relapsed multiple myeloma previously treated with chemotherapy and allogenic HSCT is described.

Lenalidomide Maintenance Therapy Reduced Risk of Progression in CLL

Lenalidomide Maintenance Therapy Reduced Risk of Progression in CLL

Results of this double-blind, phase 3 study reports on impact of lenalidomide maintenance therapy on risk of disease progression in patients with CLL who did not achieve minimal residual disease state after first-line chemoimmunotherapy.

De-escalated Radiation Therapy Improves Quality of Life in Throat Cancer

De-escalated Radiation Therapy Improves Quality of Life in Throat Cancer

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Aggressive de-escalation of chemoradiation after surgery in patients with HPV-associated OPSCC led to similar disease control and improved quality of life and safety profile compared with historical controls, according to data presented at the ASTRO 59th Annual Meeting.

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