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Cyproheptadine
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Drug Name:

Cyproheptadine Rx

Generic Name and Formulations:
Cyproheptadine HCl 4mg; scored tabs.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Cyproheptadine:

Allergic and vasomotor rhinitis, conjunctivitis, urticaria, angioedema, reactions to blood. Adjunct in anaphylaxis. Cold urticaria. Dermatographism.

Adult:

≥14yrs: initially 4mg 3 times daily; usual range 12–16mg/day; max 0.5mg/kg per day.

Children:

<2yrs: not recommended. 2–6yrs: 2mg 2–3 times per day; max 12mg daily. 7–14yrs: 4mg 2–3 times per day; max 16mg daily.

Contraindications:

MAOIs. Glaucoma. GI or urinary obstruction. Elderly. Debilitated. Neonates. Premature infants. Nursing mothers.

Warnings/Precautions:

Hyperthyroidism. Cardiovascular disease. Hypertension. Increased intraocular pressure. History of asthma. Pregnancy (Cat.B).

Interactions:

See Contraindications. Anticholinergic effects potentiated by MAOIs. Potentiates CNS depression with alcohol, other CNS depressants.

Pharmacological Class:

Antihistamine.

Adverse Reactions:

Drowsiness, dizziness, paradoxical excitement, anticholinergic effects, gastritis, hypotension, blood dyscrasias.

Note:

Formerly known under the brand name Periactin.

How Supplied:

Contact supplier.

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