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Cyclobenzaprine HCl Tablets
Muscle spasms
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Drug Name:

Cyclobenzaprine HCl Tablets Rx

Generic Name and Formulations:
Cyclobenzaprine HCl 5mg, 7.5mg, 10mg; tabs.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Cyclobenzaprine HCl Tablets:

Relief of acute muscle spasm, as adjunct to rest and physical therapy.

Adult:

≥15yrs: initially 5mg 3 times daily, may increase to 10mg 3 times daily; max 2–3 weeks. Elderly or mild hepatic impairment: initially 5mg and then titrate slowly upward.

Children:

<15yrs: not established.

Contraindications:

Acute post-MI. Arrhythmias, heart block, other conduction disturbances. CHF. Hyperthyroidism. During or within 14 days of MAOIs.

Warnings/Precautions:

Moderate-to-severe hepatic impairment: not recommended. Urinary retention. Glaucoma. Increased intraocular pressure. Elderly. Pregnancy (Cat.B). Nursing mothers.

Interactions:

See Contraindications. Hypertensive crisis with MAOIs. Increased risk of serotonin syndrome with other serotonergic drugs (eg, SSRIs, SNRIs, tricyclic antidepressants, tramadol, bupropion, meperidine, verapamil, or MAOIs); monitor closely. Potentiates anticholinergics, alcohol, other CNS depressants. May antagonize guanethidine, clonidine. Tramadol increases seizure risk.

Pharmacological Class:

Muscle relaxant (central).

Adverse Reactions:

Drowsiness, dry mouth, dizziness, fatigue, headache, GI upset, asthenia, irritability, nervousness, blurred vision, confusion, arrhythmias, tachycardia, hypotension.

Note:

Formerly known under the brand names Flexeril, Fexmid.

How Supplied:

Contact supplier.

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