Treatment with the drug crizotinib has been effective for stopping lung tumor growth driven by rearrangements of the ROS1 gene.
Patients taking crizotinib for ALK-positive non-small cell lung cancer may safely and durably use up to three courses of targeted radiation therapy to eradicate pockets of drug-resistant disease.
The current criteria used to match lung cancers with the drug crizotinib may miss some patients who could benefit from the drug. A new study suggests that doctors should look closer at borderline or atypical ALK-negative cases.
Crizotinib is superior to standard chemotherapy for treating advanced ALK-positive non-small cell lung cancer, according to the final results of a global, phase III trial.
Pockets of resistant cancer can be treated with focused, targeted radiation while continuing chemotherapy with the targeted drugs crizotinib or erlotinib.
What specific visual changes are associated with the new drug crizotinib and what causes them?
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