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CORTIFOAM
Colorectal disorders
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Drug Name:

CORTIFOAM Rx

Generic Name and Formulations:
Hydrocortisone acetate 10%; aerosol foam.

Company:
UCB Inc.

Therapeutic Use:

Indications for CORTIFOAM:

Adjunct in ulcerative proctitis in patients who cannot retain steroid enemas.

Adult:

1 applicatorful rectally (80mg hydrocortisone) 1–2 times daily for 2–3 weeks. Then every other day. Discontinue if no improvement within 2–3 weeks.

Children:

Not recommended.

Contraindications:

Rectal obstruction. Abscess. Perforation. Peritonitis. Fresh intestinal anastomoses. Extensive fistulas and sinus tracts. Tuberculosis. Ocular herpes simplex. Psychosis. Peptic ulcer. Glomerulonephritis. Myasthenia gravis. Osteoporosis. Diverticulitis. Thrombophlebitis. Diabetes. Hyperthyroidism. Acute coronary disease. Hypertension. Limited cardiac reserve. Infections.

Warnings/Precautions:

Postileorectostomy: not recommended. Exposure to varicella or vaccinia. Severe ulcerative disease. CHF. Renal or hepatic dysfunction. Monitor adrenal function and serum electrolytes. Avoid abrupt cessation. Vaccinations. Pregnancy (Cat.C). Nursing mothers.

Interactions:

May antagonize insulin or oral hypoglycemics, anticoagulants, aspirin. Hypokalemia with amphotericin B or diuretics. May be potentiated by macrolides, cyclosporine.

Pharmacological Class:

Steroid.

Adverse Reactions:

Hypertension, fluid retention, hypokalemia, adrenal suppression, cataracts, glaucoma, psychosis, dysmenorrhea, myopathy, neuropathy, thrombophlebitis, peptic ulcer, impaired wound healing, convulsions, local irritation (folliculitis, hypertrichosis, acne, hypopigmentation, macerations, dermal and epidermal atrophy, secondary infections, striae, miliaria).

How Supplied:

Aerosol—15g (w. applicator)

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