ADD THIS DRUG TO MY LIST

Select the drug indication to add to your list

CORLOPAM
Hypertension
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:

CORLOPAM Rx

Generic Name and Formulations:
Fenoldopam mesylate 10mg/mL; soln for IV infusion after dilution; contains sodium metabisulfite.

Company:
Pfizer Inc.

Therapeutic Use:

Indications for CORLOPAM:

Adults: for the in-hospital, short-term (up to 48 hours) management of severe hypertension when rapid, but quickly reversible, emergency reduction of blood pressure is clinically indicated, including malignant hypertension with deteriorating end-organ function. Children: for the in-hospital, short-term (up to 4 hours) reduction in blood pressure.

Adult:

Give by continuous IV infusion. Doses from 0.01–1.6mcg/kg/min have been studied. Initial dose should be titrated upward or downward, no more frequently than every 15 minutes (and less frequently as goal pressure is approached) to achieve desired therapeutic effect. The recommended increments for titration are 0.05–0.1mcg/kg/min.

Children:

Give by continuous infusion pump appropriate for delivery of low infusion rates. Usual starting dose: 0.2mcg/kg/min; increased dosages of up to 0.3–0.5mcg/kg/min every 20–30 minutes were generally well tolerated.

Warnings/Precautions:

Sulfite sensitivity. Glaucoma. Intraocular hypertension. Increased intracranial pressure. Acute cerebral infarction. Hemorrhage. Monitor BP, electrolytes. Pregnancy (Cat.B). Nursing mothers.

Interactions:

Avoid concomitant β-blockers.

Pharmacological Class:

Dopamine D1-like receptor agonist.

Adverse Reactions:

Headache, flushing, nausea, hypotension, tachycardia, hypokalemia.

How Supplied:

Single-dose ampule (1mL, 2mL)—1

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs