Colorectal Cancer

Skin Toxicity Evaluation in Patients Treated With Cetuximab for Metastatic Colorectal Cancer: A New Tool for More Accurate Comprehension of Quality of Life Impacts

Skin Toxicity Evaluation in Patients Treated With Cetuximab for Metastatic Colorectal Cancer: A New Tool for More Accurate Comprehension of Quality of Life Impacts

This research aims to assess the correlation between quality of life (QoL) and severity of dermatological toxicity in patients with metastatic colorectal cancer.

MSTF Releases Updated Recommendations for Colorectal Cancer Screening

MSTF Releases Updated Recommendations for Colorectal Cancer Screening

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The United States Multi-Society Task Force (MSTF) on Colorectal Cancer Screening updated its recommendations, confirming that screening in people at average risk should begin at age 50 years. The update also includes a ranking of current screening modalities.

Use of Aspirin, NSAIDs Correlates with Improved Overall Survival in Colorectal Cancer

Use of Aspirin, NSAIDs Correlates with Improved Overall Survival in Colorectal Cancer

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Regular use of NSAIDs after diagnosis of colorectal cancer correlated with improved survival in survivors with KRAS wild-type tumors.

Doxorubicin Efficacy Improved, Cardiotoxicity Reduced With Adjuvant Fidarest for Colon Cancer

Doxorubicin Efficacy Improved, Cardiotoxicity Reduced With Adjuvant Fidarest for Colon Cancer

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The AR inhibitor fidarestat is effective as adjuvant therapy to enhance doxorubicin sensitivity of colorectal cancer cells and to reduce cardiotoxicity associated with the drug.

Navigating Colorectal and Pancreatic Cancer Patients in a Multidisciplinary Cancer Center

Navigating Colorectal and Pancreatic Cancer Patients in a Multidisciplinary Cancer Center

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By identifying incidence, prevalence, and risk factors for colorectal and pancreatic cancer in our communities, nurse navigators can develop screening and prevention programs to better serve these populations.

Patient and Physician Preferences for Anticancer Drugs for the Treatment of Metastatic Colorectal Cancer: A Discrete-choice Experiment

Patient and Physician Preferences for Anticancer Drugs for the Treatment of Metastatic Colorectal Cancer: A Discrete-choice Experiment

[Cancer Management and Research] This research examines preferences and risk tolerance among patients and oncologists in the USA for anticancer drugs to treat metastatic colorectal cancer (mCRC).

No Serious HRQOL Decline With FOLFOXIRI/Bevacizumab

No Serious HRQOL Decline With FOLFOXIRI/Bevacizumab

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Study compared FOLFOXIRI/bevacizumab and FOLFOX/bevacizumab in patients with metastatic colorectal cancer.

Cancer Recurrence Fear Reduced by Novel Psychological Intervention

Cancer Recurrence Fear Reduced by Novel Psychological Intervention

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'Conquer Fear' decreased fear among survivors of breast and colorectal cancer and melanoma compared with relaxation techniques.

Tumor Mutation Load Higher in Younger Patients With Colon Cancer

Tumor Mutation Load Higher in Younger Patients With Colon Cancer

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Tumor mutation load (TML) may be a factor in higher rates of colorectal cancer among younger persons as TML is 3 times higher in younger patients with colorectal cancer.

Comprehensive After Surgery Recovery Program Reduces Complication Rates and Improves Surgical Outcomes

Comprehensive After Surgery Recovery Program Reduces Complication Rates and Improves Surgical Outcomes

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Postoperative program improves complication rates, opioid prescribing, and hospital mortality and increases home discharge rates after colorectal or hip fracture surgery.

Prunes and Colon Cancer Prevention

Prunes and Colon Cancer Prevention

Scientists at Texas A&M University traced how eating a daily dose of prunes affects colon biochemistry, and the role this diet may play in cancer prevention.

Risk for Disease, Advanced Stage at Diagnosis Higher With Delayed Colonoscopy After Positive FIT Results

Risk for Disease, Advanced Stage at Diagnosis Higher With Delayed Colonoscopy After Positive FIT Results

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Waiting 10 months or longer before follow-up colonoscopy after a positive FIT result is associated with higher risk of disease as well as advanced stage at diagnosis.

Prebiotic Qualities of Dried Plums Identified as a Colon Cancer Preventative

Prebiotic Qualities of Dried Plums Identified as a Colon Cancer Preventative

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Consuming the equivalent of 5 prunes per day may provide a unique combination of biologically active compounds that can reduce the risk of colon cancer.

Beans, Whole Grains in Diet Beneficial for Colorectal Cancer Survivors

Beans, Whole Grains in Diet Beneficial for Colorectal Cancer Survivors

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Including beans and whole grains such as rice in the diet is associated with a reduced burden of CRC in survivors.

Self-efficacy Level Predictive of Likelihood to Follow Through With Colorectal Cancer Screening

Self-efficacy Level Predictive of Likelihood to Follow Through With Colorectal Cancer Screening

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Patients' confidence with colorectal cancer screening procedures is predictive of their likelihood to schedule and follow through with screening.

Survival Better for Hispanics, Blacks With Colorectal Cancer but HR-QoL Is Better for Whites

Survival Better for Hispanics, Blacks With Colorectal Cancer but HR-QoL Is Better for Whites

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Although median survival is longer for Hispanic and black patients compared with white patients, health-related QoL is poor for minority patients.

Rates of Colorectal Cancer Screening Lower for Adults With Disabilities

Rates of Colorectal Cancer Screening Lower for Adults With Disabilities

Transportation issues, lack of awareness, other barriers may be to blame for diminished colorectal screening rates.

Lifestyle Choices Have Greater Influence on Colon and Rectal Cancer Risk

Lifestyle Choices Have Greater Influence on Colon and Rectal Cancer Risk

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Predictive risk model shows that lifestyle choices have a greater influence on risk for colorectal cancer than does genetic factors.

Colorectal Cancer Rates Increased Sharply Among Generation X and Millennials

Colorectal Cancer Rates Increased Sharply Among Generation X and Millennials

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Incidence of colon and rectal cancers are increasing sharply in people younger than 50 years, the recommended age for initiating screening.

Colorectal Cancer in 2017: Incidence Rates Going Up in Younger Patients, Down in Older Patients

Colorectal Cancer in 2017: Incidence Rates Going Up in Younger Patients, Down in Older Patients

ACS colorectal cancer statistics show an overall decrease in incidence due to increases in screening rates; however, age-related incidence is trending up in younger persons, down in older persons.

Short-Course Radiation With Delay to Surgery Improves Outcomes in Rectal Cancer

Short-Course Radiation With Delay to Surgery Improves Outcomes in Rectal Cancer

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Outcomes improved with short-course radiation and delay to surgery of 4 to 8 weeks.

Colorectal Cancer Risk Higher With Poor Metabolic Health vs Increased Weight

Colorectal Cancer Risk Higher With Poor Metabolic Health vs Increased Weight

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Women with poor metabolic health have a greater risk of colorectal cancer than those with increased weight.

Geographic Location Affects Stage at Diagnosis of Colon Cancer in Segregated Communities

Geographic Location Affects Stage at Diagnosis of Colon Cancer in Segregated Communities

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Geographic location was seen to affect disease stage at diagnosis among people with colorectal cancer who live in ethnically or racially segregated communities.

MABp1 Improves Symptoms vs Placebo in Colorectal Cancer

MABp1 Improves Symptoms vs Placebo in Colorectal Cancer

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MABp1 (Xilonix) is an interleukin 1α-targeting antibody associated with antitumor activity and relief of debilitating symptoms in patients with advanced colorectal cancer. In this ongoing phase 3 clinical trial, its impact on other debilitating symptoms in this population was evaluated.

ASCO: Moderate Activity Linked to Longer Survival in Advanced CRC

ASCO: Moderate Activity Linked to Longer Survival in Advanced CRC

Moderate but not vigorous activity proved beneficial for patients with metastatic colorectal cancer.

Omega-3 Polyunsaturated Fatty Acids in the Prevention of Postoperative Complications in Colorectal Cancer: A Meta-analysis

Omega-3 Polyunsaturated Fatty Acids in the Prevention of Postoperative Complications in Colorectal Cancer: A Meta-analysis

[OncoTargets and Therapy] This research evaluates the clinical efficacy of omega-3 PUFAs in the prevention of postoperative complications in colorectal cancer patients.

NSAIDs, Low-Dose Aspirin Best Options for Preventing Recurrent Adenomatous Colon Polyps

NSAIDs, Low-Dose Aspirin Best Options for Preventing Recurrent Adenomatous Colon Polyps

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Researchers compared the effectiveness of NSAIDs, aspirin, and several nutritional supplements for the prevention of recurrent adenomatous neoplasia after colon polyp removal.

Drug-Drug Interaction Between Capecitabine and PPIs Reduces Survival in GI Cancers

Drug-Drug Interaction Between Capecitabine and PPIs Reduces Survival in GI Cancers

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Drug-drug interaction between capecitabine and common heartburn medications has a negative effect on progression-free survival and overall survival in patients with GI cancer.

Multigene Panel Testing For Patients With Early-onset Colorectal Cancer

Multigene Panel Testing For Patients With Early-onset Colorectal Cancer

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Given the frequency of gene mutations in patients with early-onset CRC, genetic counseling and testing could be considered for this population.

Prehabilitation Program Improves Preoperative Fitness in Patients With Colorectal Cancer

Prehabilitation Program Improves Preoperative Fitness in Patients With Colorectal Cancer

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Study results demonstrate effectiveness of 4 weeks of prehabilitation on the physical fitness of older patients undergoing surgery for colorectal cancer.

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