Colorectal Cancer

Prehabilitation Program Improves Preoperative Fitness in Patients With Colorectal Cancer

Prehabilitation Program Improves Preoperative Fitness in Patients With Colorectal Cancer

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Study results demonstrate effectiveness of 4 weeks of prehabilitation on the physical fitness of older patients undergoing surgery for colorectal cancer.

Study Helps to Clarify Navigator Role in Colonoscopy Screening

Study Helps to Clarify Navigator Role in Colonoscopy Screening

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Survey data from patients receiving care at Boston Medical Center who were navigated for colonoscopy screening illustrates how patients value the services of oncology patient navigators.

Prediagnostic Wine Consumption May Improve Survival After CRC

Prediagnostic Wine Consumption May Improve Survival After CRC

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A possible association between moderate to heavy alcohol consumption has been shown in previous studies. In this study, investigators examined the relationship between alcohol consumption and colorectal cancer survival remains unclear.

Side of Origin Affects Colon Cancer Survival

Side of Origin Affects Colon Cancer Survival

Researchers observed a significant disparity in colon cancer mortality related to origin location, independent of confounding variables.

Benefits of FIT As CRC Screening Method Examined

Benefits of FIT As CRC Screening Method Examined

FIT has several advantages over gFOBT, but practical concerns should be considered

Replacing Neoadjuvant CRT with Multiagent Chemo Not Recommended for Rectal Cancer

Replacing Neoadjuvant CRT with Multiagent Chemo Not Recommended for Rectal Cancer

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In this study, the impact of advancements in surgical technique and systemic therapy for stage II and III rectal cancers was assessed via a comparison of outcomes after neoadjuvant chemoradiotherapy followed by definitive resection with those for neoadjuvant multiagent chemotherapy without radiation therapy.

Men With Genetic Risk of CRC May Lower Risk Via Healthy Lifestyle

Men With Genetic Risk of CRC May Lower Risk Via Healthy Lifestyle

Adopting healthy lifestyle can cut 25-year risk for the disease from 29 to 13 percent.

Novel Colonoscopy Prep Is Poised to Improve Screening Rates for Colon Cancer

Novel Colonoscopy Prep Is Poised to Improve Screening Rates for Colon Cancer

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Novel preparation formulation is as effective and safe as current colon prep for colonoscopy. Plus, study participants gave the prep experience a high satisfaction rating.

Health Insurance Expansion Linked to Improved CRC Resection Rates

Health Insurance Expansion Linked to Improved CRC Resection Rates

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The model for the Affordable Care Act, the 2006 Massachusetts health care reform, was associated with increased resection rates and a reduced risk for emergency resection in patients with colorectal cancer.

New CRC Screening Option Opens the Door for New Conversations

New CRC Screening Option Opens the Door for New Conversations

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A new colorectal cancer (CRC) screening test that can be done in the privacy of patients' homes, at their convenience, and with no prep needed may help patients overcome their reticence.

Adding Bevacizumab to Adjuvant Capecitabine Not Effective for mCRC

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The combination of adjuvant bevacizumab and capecitabine failed to improve disease-free survival compared with capecitabine alone in patients with mCRC who had undergone potentially curative surgery.

Rolapitant Improves CINV Prevention in Patients With GI Cancers

Rolapitant Improves CINV Prevention in Patients With GI Cancers

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Adding rolapitant to a 5-HT3 receptor antagonist and dexamethasone significantly improved the prevention of CINV in patients with GI and CRC cancers receiving highly or moderately emetogenic chemotherapy.

Study Identifies Factors Associated With Poor Care Coordination

Study Identifies Factors Associated With Poor Care Coordination

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Patients who have little to no understanding of the health system, multiple comorbid conditions, do not receive a written treatment plan, or do not have contact with a cancer care coordinator or specialist nurse have significantly poorer care coordination.

Increasing Dietary Omega-3 Intake After Colorectal Cancer Diagnosis Improves Survival

Increasing Dietary Omega-3 Intake After Colorectal Cancer Diagnosis Improves Survival

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Lifestyle and dietary measures for preventing colorectal cancer are extensively studied; however, in this study, researchers looked at a dietary measure that improved survival for patients after diagnosis.

Recently Discovered microRNA Controls Response to Oxaliplatin in Colorectal Cancer

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Danish researchers identified a microRNA shown to predict whether a patient with colorectal cancer would be resistant to oxaliplatin treatment, a discovery that holds promise of improving both current treatment options and development of future treatment strategies.

Metformin Use May Improve Survival in Patients With CRC, Diabetes

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Research indicates that metformin can confer improved survival for patients with colorectal cancer that also have diabetes.

Adjuvant Therapy Improves Survival in Stage II Colon Cancer, Study Confirms

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A very large retrospective study of patients with stage II colon cancer found adjuvant therapy improves survival, regardless of treatment regimen, patient age, or high-risk pathologic risk features.

Immunotherapy Combination is Effective in Colorectal Cancer

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Cbimetinib and atezolizumab was well tolerated and demonstrated encouraging clinical activity in microsatellite stable colorectal cancer (CRC).

Advanced Endoscopy Techniques May Be Safe Alternative to Surgery for Most Difficult-to-Remove or Large Polyps

Advanced Endoscopy Techniques May Be Safe Alternative to Surgery for Most Difficult-to-Remove or Large Polyps

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Most patients with large or difficult-to-remove colorectal polyps have a lower incidence of cancer than previously thought; therefore, more advanced endoscopic techniques that spare the colon may be a better and safer alternative to a traditional operation in some cases.

Blood Biomarker Is Predictive of Risk for Colon Cancer Recurrence

Blood Biomarker Is Predictive of Risk for Colon Cancer Recurrence

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Genetic biomarkers from tumor DNA circulating in the bloodstream could indicate the risk for recurrence of colorectal cancer and the efficacy of chemotherapy after surgery.

In Stage II Colon Cancer, Adjuvant Chemo is Associated With Improved OS

In Stage II Colon Cancer, Adjuvant Chemo is Associated With Improved OS

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Adjuvant chemotherapy is associated with improved overall survival in patients with stage II colon cancer regardless of treatment regimen, patient age, or high-risk pathologic risk features.

Rare Mutations in Immune-Related Genes Linked to Multiple Simultaneous Colorectal Cancer Tumors

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Genetic mutations affecting the immune system were identified in patients who develop more than one CRC tumor at the same time, and understanding how these cancers develop could improve therapy targeting.

Elderly Patients Often Not Up-to-Date on Screening for Colorectal Cancer

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Screening for colorectal cancer (CRC) is not widely used by Americans age 75 years and older, even though some patients are healthy and may benefit.

More Older Patients With Comorbidities Are Receiving Therapy for mCRC

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The proportion of older patients with comorbidities receiving treatment for metastatic colorectal cancer (mCRC) has increased over the last 2 decades despite the overall percentage of older adults being treated remaining low.

Genetic Picture of Colorectal Cancer Expanded

Genetic Picture of Colorectal Cancer Expanded

Researchers say it's likely that all the major genetic mutations related to colorectal cancer have been discovered.

Walnut Consumption Changes Gut Microbiome, Decreases Growth of Colon Cancer in Mice

Walnut Consumption Changes Gut Microbiome, Decreases Growth of Colon Cancer in Mice

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Consumption of walnuts reduced the growth of colon cancer. Researchers saw a reduction in tumor growth in mice that ate the equivalent of approximately 1 ounce of walnuts a day.

Patient Navigation Significantly Improves Cancer Screening Rates

Patient Navigation Significantly Improves Cancer Screening Rates

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The addition of a patient navigation component to a population-based IT system boosted screening rates for breast cancer, cervical cancer, and colorectal cancer in patients at high risk for nonadherence.

Free Colonoscopy Screening for Uninsured Patients Effectively Detects CRC Early and Is Cost Neutral

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Offering free screening colonoscopies can identify CRC earlier in uninsured patients who are at high risk for developing the disease. In addition, the program is cost neutral from the perspective of a hospital system.

Rates of Colorectal Cancer Are Increasing in Younger Patients, Despite an Overall Decline

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Reasons for the continuing increase in cases of young-onset colorectal cancer, despite a decline in the overall rate of the disease in recent years, are unclear.

Evidence Mounts That Low-Dose Aspirin Improves Survival in CRC

Evidence Mounts That Low-Dose Aspirin Improves Survival in CRC

Greatest survival benefit observed for those taking the drug before their cancer diagnosis.

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