Androgens

ANDROGENS
Generic Brand Strength Dose
Capsules
methyl-
testosterone
Android 10mg Adults and Children: Usually 10−50mg daily. Delayed puberty: use low dose and limit duration to 4−6mos.
Testred 10mg
INTRAMUSCULAR INJECTION
testosterone cypionate Depo-Testos-
terone
100mg/mL, 200mg/mL Adults: Give by deep IM inj into gluteal muscle once every 2−4wks. 50−400mg; max 400mg/month.
Children: Not recommended.
testosterone enanthate Delatestryl 200mg/mL Adults: Give by deep IM inj into gluteal muscle once every 2−4wks. Male hypogonadism: 50−400mg. Delayed puberty: 50−200mg. Max 400mg/month.
Children: Not recommended.
testosterone undecanoate AVEED 250mg/mL ≥18yrs: Give by deep IM inj into gluteal muscle. 3mL (750mg) once at initiation, followed by 3mL (750mg) at 4wks, then 3mL (750mg) every 10wks thereafter.
<18yrs: Not established.
MUCOADHESIVE BUCCAL TABLET
testosterone Striant 30mg ≥18yrs: 30mg applied to the gum (above incisors) every 12hrs (AM & PM); hold in place for 30secs; rotate appl. sites. Do not chew or swallow tab.
<18yrs: Not established.
Tablets
fluoxy-
mesterone
10mg Adults: Male hypogonadism: 5−20mg/day.
Children: Delayed puberty: Use low dose, with appropriate skeletal monitoring. Duration of therapy: 4−6mos.
methyl-
testosterone
Methitest 10mg Adults and Children: Usually 10−50mg daily. Delayed puberty: use low dose and limit duration to 4−6mos
oxandrolone Oxandrin 2.5mg, 10mg
TRANSDERMAL GEL
testosterone Androgel 1%* 12.5mg/
 
1.25g per pump actuation
≥18yrs: Apply to clean, intact, dry skin of the shoulders, upper arms, and/or abdomen; do not apply to genitals, chest, axillae, knees, or back. 5g (50mg of testosterone) once daily in AM; check serum testosterone level at intervals until normal range; may increase to 7.5g/day (75mg of testosterone), then to 10g/day (100mg of testosterone) if needed.
<18yrs: Not established.
25mg/2.5g, 50mg/5g pkt
Androgel 1.62%* 20.25mg/
 
1.25g per pump actuation
≥18yrs: Apply to clean, intact, dry skin of the shoulders and upper arms; do not apply to abdomen, genitals, chest, axillae, or knees. 2.5g (40.5mg of testosterone [2 pump actuations]) once daily in AM. May adjust dose between min of 20.25mg (1 pump actuation) and a max of 81mg (4 pump actuations) based on the pre‑dose morning serum testosterone concentration at approx. 14 days and 28 days after starting treatment or following dose adjustment.
<18yrs: Not established.
20.25mg/
 
1.25g, 40.5mg/
 
2.5g pkt
Fortesta* 10mg/0.5g per pump actuation ≥18yrs: Apply to clean, dry, intact skin on front and inner thighs only. Initially 40mg (4 pump actuations) once daily in the AM. Adjust based on serum testosterone levels (see full labeling); min: 10mg/day, max: 70mg/day.
<18yrs: Not established.
Testim* 50mg/5g ≥18yrs: Apply to clean, dry intact skin of the shoulders and/or upper arms; do not apply to genitals or abdomen. Initially apply 5g (1 tube) once daily in the AM; measure serum testosterone level to ensure response; may increase to 10g after 2wks.
<18yrs: Not recommended.
Vogelxo* 50mg/5g per tube or pkt ≥18yrs: Apply to clean, dry intact skin of the shoulders and/or upper arms at the same time each day; do not apply to scrotum or abdomen. 50mg (1 tube or pkt or 4 pump actuations) once daily; check morning, pre‑dose serum testosterone levels approx. 14 days after initiation; may increase to 100mg (2 tubes or pkts or 8 pump actuations) once daily if needed; max 100mg once daily.
<18yrs: Not established.
12.5mg/
 
1.25g per pump actuation
TRANSDERMAL PATCH
testosterone Androderm 2mg/day, 4mg/day ≥18yrs: Initially apply one 4mg/day system nightly for 24hrs to intact clean, dry skin of the back, abdomen, thighs, or upper arms. Avoid bony prominences and areas subject to pressure during sleep or sitting. Rotate appl. sites at intervals of 7 days. Increase to 6mg (one 4mg/day + one 2mg/day system) or decrease to 2mg (one 2mg/day system) based on confirmed AM serum testosterone concentrations.
<18yrs: Not recommended.
TRANSDERMAL SOLUTION
testosterone Axiron* 30mg/
 
1.5mL
per pump actuation
≥18yrs: Apply to clean, dry intact skin of the axilla; do not apply to the scrotum, penis, abdomen, shoulders or upper arms. Initially apply 60mg (30mg per axilla) once daily in the AM; measure serum testosterone levels to ensure response. May adjust dose based on serum testosterone concentration 2−8hrs after applying and at least 14 days after starting therapy or following dose adjustment. May increase dose in 30mg increments if serum testosterone <300ng/dL up to 120mg; reduce dose to 30mg if levels >1050ng/dL, discontinue if serum testosterone remains >1050ng/dL.
<18yrs: Not established.
NOTES

*Wash hands after application. Do not wash site for at least 2hrs after application. Allow gel or solution to dry before covering with clothing. Advise patients to strictly adhere to recommended instructions.

Not an inclusive list of medications and/or official indications. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling.

(Rev. 2/2015)

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