Whole Genome Sequencing Reveals that 12% of Childhood Cancer Survivors Have Mutations in Genes that Increase Cancer RiskApril 19, 2017
Whole genome sequencing of more than 3000 survivors of childhood cancers demonstrates the value of genetic testing for potential second cancers in this population.
Arm anthropometry is a better tool for assessing nutritional status of survivors of childhood cancer.
Cancer deaths within 1 month of diagnosis occur most often in patients younger than 1 years, especially among Blacks and Hispanics.
A significant reduction in use of radiation therapy to treat childhood cancers improved survival, reduced second cancers in survivors.
Three specific genetic alterations may help identify pediatric patients with AMKL at high risk who may benefit from allogeneic stem cell transplants.
Study results indicate that herpetic cytomegalovirus infection prior to birth subjects the child to increased odds of developing pediatric acute lymphoblastic leukemia.
Large cohort study assesses the frequency of, and factors associated with, ototoxicity in childhood cancer survivors who received platinum agents without cranial irradiation.
Research shows only modest improvements in the physical or mental health of childhood cancer survivors in recent decades.
Epidemiologic study reveals the impact of cancer and its treatment on diet quality among adult survivors of childhood cancers.
Internalizing, Externalizing Behavioral Problems a Significant Postdiagnosis Concern in Children With CancerOctober 11, 2016
Children with cancer are at risk for developing behavioral problems after diagnosis.
A twenty percent decrease in cancer death rate among children and adolescents has taken place from 1999 to 2014.
Adult survivors of childhood cancer are at increased risk for late adverse pulmonary events.
Although most adolescent survivors of childhood cancer have no reported psychological symptoms, those who do often have multiple symptoms and distinct symptom profiles.
Chronic conditions commonly affect long-term quality of life for survivors of childhood cancer who are in their young adult years.
The experimental treatment LOXO-101 led to remarkable improvement for a 20-month-old girl whose rare pediatric cancer did not respond to surgery or chemotherapy.
Two new compounds suppress tumor growth in cell culture and mouse xenograft models of Ewing sarcoma, a rare pediatric cancer. These 2 compounds are similar to mithramycin, also known as picamycin, a drug no longer manufactured due to its toxicity.
Anxiety and Depressive Symptoms Are Increased in Pediatric Survivors of Acute Lymphoblastic LeukemiaApril 04, 2016
Emotional distress during and after undergoing chemotherapy for ALL affects a significant percentage of children with the disease.
Study Findings Show Possible Association Between PreLabor Cesarean Delivery and Risk for ALL in Young ChildrenMarch 16, 2016
The finding that prelabor cesarean delivery may have a correlation with acute lymphoblastic leukemia (ALL) may offer new targets for research into preventing cancer.
A group of pediatric oncology psychosocial experts developed evidence-based standards for the care of children with cancer and their families.
[OncoTargets and Therapy] Anaplastic large cell lymphoma (ALCL) frequently involves the bone marrow, but primary or secondary involvement to the bone is rare. This article examines a case of anaplastic lymphoma kinase positive ALCL with prominent bone involvement in a young boy.
Treating medulloblastoma with proton beam therapy results in survival rates in line with other proton therapies, according to recent study data.
Early cardiovascular events are a risk for survivors of childhood cancer, according to researchers who also advocate for a unified definition of pediatric metabolic syndrome.
Phase 2 trial data showed acceptable toxicity and similar survival as conventional radiotherapy for childhood medulloblastoma.
Lifelong screening is recommended for survivors of childhood cancer that affects the vision, in order to detect issues early.
New Studies Reveal Long-Term Vision-related Health Concerns of Survivors of Childhood Retinoblastoma and Brain CancerJanuary 11, 2016
Two new studies investigate the impact of retinoblastoma on long-term health of survivors and the long-term psychological and socio-economic effects of blindness in survivors of brain tumors.
Exposure to anthracycline and heart radiation has been tied to higher odds of cardiac disease.
Association Is Found Between Bone Complications in Young Pediatric Patients With Leukemia and Gene VariationsDecember 22, 2015
Variations in genes involved in normal bone development are associated with an 8- to 15-fold increased risk for osteonecrosis in young patients with acute lymphoblastic leukemia (ALL).
Immunophenotypic expression profiles can provide a tool to discriminate cohorts of young patients with acute myeloid leukemia (AML) that have a high relapse probability.
Although a fourth chemotherapy course may benefit younger patients with poor-risk acute myeloid leukemia, those with good and standard risk demonstrated little survival benefit from the additional course.
Continuous antibiotic treatment can reduce infections in young patients with acute lymphoblastic leukemia (ALL).
- Increased 5-Year Survival Rate Seen in NSCLC Subset Treated With Nivolumab
- Health Care Expansion Tied to Increased Rates of Surgical Treatment of Thyroid Cancer
- JAK1, JAK2 Inhibition Improves Outcomes in Myeloproliferative Neoplasms, But More Is Needed
- Including a PI3-Kinase Inhibitor with an PARP Inhibitor Improves Tumor Shrinkage in Patients with Resistant Ovarian Cancer
- Hormone Refractory Prostate Cancer Responds to Abiraterone Acetate in Some Cases
- Exercise, Psychological Interventions Better for Cancer Fatigue Than Medications
- ASCO Issues Global Guidance for HPV Vaccination for Cervical Cancer Prevention
- Discharge Events Improved With Standardized Inpatient Palliative Care Consultation
- Little Opposition to Early Palliative Care for Symptom Management in Pediatric Oncology
- Physical Activity Improves Outcomes for Patients with Breast Cancer and Survivors
- CQGS Releases Standards for Surgical Care of Older Adults
- Radiation Protocol Deviations Linked to Worse Outcomes in Pediatric Brain Malignancy
- Use of Counseling, Surgery Rates Show Limited Physician Knowledge of Breast Cancer Genetic Testing
- Family History Does Not Exclude Active Surveillance as Treatment Option for Prostate Cancer
- Beans, Whole Grains in Diet Beneficial for Colorectal Cancer Survivors
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