Chemotherapy

QOL, Adverse Effects Better With Capecitabine After Adjuvant Epirubicin for Breast Cancer

QOL, Adverse Effects Better With Capecitabine After Adjuvant Epirubicin for Breast Cancer

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Women with breast cancer who received capecitabine after adjuvant epirubicin had better quality of life (QOL) compared with those who received CMF after adjuvant therapy.

Taxane-based Chemotherapy May Diminish Balance, Gait in Breast Cancer Survivors

Taxane-based Chemotherapy May Diminish Balance, Gait in Breast Cancer Survivors

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Breast cancer survivors who received taxane-based chemotherapy for their disease are at increased risk for falls due to CIPN and treatment-associated effects on balance and gait.

Wait Times From Cancer Diagnosis to First Treatment Longer, Negative Impact on Survival

Wait Times From Cancer Diagnosis to First Treatment Longer, Negative Impact on Survival

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Data from the National Cancer Database are indicating that wait times from cancer diagnosis to initial treatment were substantially longer over a 5-year period.

Pembrolizumab Use With CRT Safe in Locally Advanced HNSCC

Pembrolizumab Use With CRT Safe in Locally Advanced HNSCC

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Small study also showed that pembrolizumab does not significant impair radiation or chemotherapy dosing.

Ovarian Function Recovery May Increase Risk of Breast Cancer Recurrence

Ovarian Function Recovery May Increase Risk of Breast Cancer Recurrence

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Ovarian function recovery (OFR) in women with chemotherapy-induced ovarian function failure decreases residual 5-year disease-free and overall survival.

Adjuvant Bevacizumab Does Not Increase Survival in High-Risk Melanoma

Adjuvant Bevacizumab Does Not Increase Survival in High-Risk Melanoma

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Five-year survival rate found similar to observation despite a significant improvement in disease-free interval.

Lanreotide Eases Carcinoid Syndrome Symptoms in All Patients

Lanreotide Eases Carcinoid Syndrome Symptoms in All Patients

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Lanreotide decreased the proportion of days patients had flushing and diarrhea compared with placebo, even in patients previously responsive to rescue therapy with octreotide.

Mobile App May Improve Oral Chemotherapy Adherence

Mobile App May Improve Oral Chemotherapy Adherence

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Patients with adherence problems were more likely to take their pills compared with those who received standard care.

ESW Technique Improves Nanoparticle Drug Delivery to Solid Tumors with Restricted Blood Flow

ESW Technique Improves Nanoparticle Drug Delivery to Solid Tumors with Restricted Blood Flow

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Combining extracorporeal shock wave (ESW) technique with nanoparticle delivery improves treatment of difficult-to-treat solid tumors, such as anaplastic thyroid cancer.

Risk of Bladder Recurrence Reduced With Chemotherapy Flush After Tumor Resection

Risk of Bladder Recurrence Reduced With Chemotherapy Flush After Tumor Resection

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Flushing the bladder with a chemotherapeutic agent after tumor resection significantly reduced recurrence rates of bladder cancer.

No Improvement in KRAS-Mutation Lung Cancer With MEK Inhibitor Plus Chemotherapy

No Improvement in KRAS-Mutation Lung Cancer With MEK Inhibitor Plus Chemotherapy

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A combination treatment of mitogen-activated protein kinase MEK inhibitor and chemotherapy did not improve progression-free survival in patients with advanced lung cancer caused by a KRAS gene mutation.

Significant Reductions in CLABSIs Achieved With Daily Chlorhexidine Bathing in Oncology Population

Significant Reductions in CLABSIs Achieved With Daily Chlorhexidine Bathing in Oncology Population

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Daily CHG bathing can safely reduce CLABSIs in oncology patients with central lines, with small variations in efficacy of the practice due to differences in patient population, work processes, and team engagement.

Cisplatin Plus Standard-of-Care Regimen Reduced Tumors in Advanced Pancreatic Cancer

Cisplatin Plus Standard-of-Care Regimen Reduced Tumors in Advanced Pancreatic Cancer

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Cisplatin plus standard-of-care gemcitabine/nab-paclitaxel improved tumor shrinkage in patients with metastatic pancreatic cancer, according to a study by the HonorHealth Research Institute and the Translational Genomics Research Institute.

Research Shows Temozolomide Has Potential to Increase Depression

Research Shows Temozolomide Has Potential to Increase Depression

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Temozolomide, an antimitotic chemotherapy used to treat brain cancer, demonstrated the potential to increase depression in a mouse model.

Standardized Assessment Tool Prevents Chemotherapy-Induced Neurotoxicity

Standardized Assessment Tool Prevents Chemotherapy-Induced Neurotoxicity

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Standardized tool improved efficiency and thoroughness of patient assessment and documentation of neurotoxicity caused by high-dose cytarabine.

Education and Coaching Are Necessary to Treat Oropharyngeal Cancers After Chemoradiotherapy

Education and Coaching Are Necessary to Treat Oropharyngeal Cancers After Chemoradiotherapy

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A literature review noted improvements in quality of life after patients were coached and educated following radiotherapy for HPV-associated oropharyngeal cancers.

New Closed System Drug Transfer Device Can Reduce Nurse Exposure to Antineoplastic Hazardous Drugs

New Closed System Drug Transfer Device Can Reduce Nurse Exposure to Antineoplastic Hazardous Drugs

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A new CSTD significantly reduced surface contamination during a simulated antineoplastic hazardous drug administration when compared to baseline.

Standardized Process for Assessing Chemotherapy Appointments Improves Patient Wait Times

Standardized Process for Assessing Chemotherapy Appointments Improves Patient Wait Times

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Prior assessment of patients and review of infusion orders by an interprofessional ACE team can significantly reduce patient wait times, prevent same-day inefficiencies, and reduce wasted chemotherapy doses.

Rolapitant Eases CINV in Patients Receiving Highly, Moderately Emetogenic Chemotherapy

Rolapitant Eases CINV in Patients Receiving Highly, Moderately Emetogenic Chemotherapy

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Long-acting NK-1 receptor antagonist rolapitant demonstrates significant efficacy in managing CINV in patients receiving HEC or MEC for cancer.

Follow-up Surgery Not Needed When Breast Cancer Responds to Neoadjuvant Chemotherapy

Follow-up Surgery Not Needed When Breast Cancer Responds to Neoadjuvant Chemotherapy

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Women with triple-negative or HER2-positive breast cancer who achieve a pathologic complete response from neoadjuvant chemotherapy may be able to avoid follow-up breast or lymph node surgery.

Online Module Seeks to Educate Nurses on the Identification and Management of Hypersensitivity Reactions to Chemotherapy

Online Module Seeks to Educate Nurses on the Identification and Management of Hypersensitivity Reactions to Chemotherapy

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Hypersensitivity reactions in patients receiving chemotherapy are not common, but their serious nature requires that oncology nurses be able to manage them when they occur.

Short-Term Fasting Alleviates Toxic Effects, High Glucose Levels Associated With Chemotherapy

Short-Term Fasting Alleviates Toxic Effects, High Glucose Levels Associated With Chemotherapy

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Short-term fasting may alleviate toxic effects caused by high blood glucose levels associated with common cancer drugs.

High-Dose Vitamin C Infusions Increase Cancer Cell Sensitivity to Chemotherapy, Radiation

High-Dose Vitamin C Infusions Increase Cancer Cell Sensitivity to Chemotherapy, Radiation

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Regular infusions of high doses of vitamin C safely increased cancer cell sensitivity to treatment in patients with brain and lung cancers.

Exercise Improves Coping While Undergoing Chemotherapy for Advanced GI Cancer

Exercise Improves Coping While Undergoing Chemotherapy for Advanced GI Cancer

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Exercise helps patients with gastrointestinal cancer undergoing chemotherapy cope with their disease and treatment.

Everolimus Found to Improve Chemotherapy-Induced Infertility in Preclinical Research

Everolimus Found to Improve Chemotherapy-Induced Infertility in Preclinical Research

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A study using a mouse model to investigate the effect of adding everolimus to cyclophosphamide to slow tumor growth found the drug also preserves fertility.

Regorafenib Improves Quality-adjusted Survival in Sarcoma

Regorafenib Improves Quality-adjusted Survival in Sarcoma

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In patients with soft tissue sarcoma pretreated with doxorubicin, treatment with regorafenib significantly reduced the risk of progression symptoms or toxicity.

Chemotherapy or VBT Improve Survival in Uterine Papillary Serous Carcinoma

Chemotherapy or VBT Improve Survival in Uterine Papillary Serous Carcinoma

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Use of chemotherapy or vaginal brachytherapy (VBT) may improve survival among patients with early-stage uterine papillary serous carcinoma.

Research Shows Vitamin B3 Reduces Pain From Chemotherapy-Induced Peripheral Neuropathy

Research Shows Vitamin B3 Reduces Pain From Chemotherapy-Induced Peripheral Neuropathy

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Nicotinamide riboside, a type of B3 vitamin, was shown to prevent chemotherapy-induced peripheral neuropathy in an animal-model study.

Skeletal Muscle Mass, Composition Is Predictive of Treatment-Related Toxicity in Breast Cancer

Skeletal Muscle Mass, Composition Is Predictive of Treatment-Related Toxicity in Breast Cancer

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Quantity and quality of skeletal muscle is a more accurate measure for determining dose and of potential treatment-related toxicity in patients receiving chemotherapy for early-stage breast cancer.

Ginger Extract Raises Antioxidant Levels in Patients Undergoing Chemotherapy

Ginger Extract Raises Antioxidant Levels in Patients Undergoing Chemotherapy

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Supplemental ginger before and during treatment raises antioxidant levels in patients undergoing chemotherapy.

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