Chemotherapy

Patient beliefs about chemotherapy, cancer influence care choices at the end of life

Patient beliefs about chemotherapy, cancer influence care choices at the end of life

Patients with advanced cancer who believed chemotherapy might cure their cancer were more likely to receive chemotherapy.

Hair dye use during chemotherapy

Hair dye use during chemotherapy

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Is it safe to use hair dyes concurrently with chemotherapy?

Assessing patency of an implanted port

Assessing patency of an implanted port

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How should a fibrin overgrowth on an internal catheter be managed when there is no blood return from the implanted port?

Rare gene variants associated with side effects from paclitaxel

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Researchers have identified the first genetic marker associated with severe neurologic toxicity from paclitaxel.

Immunosuppressives and anticancer drugs may reactivate Hepatitis B virus (HBV)

Immunosuppressives and anticancer drugs may reactivate Hepatitis B virus (HBV)

Chemotherapy or immunosuppressive treatment may reactive hepatitis B virus in patients previously infected with the virus.

Potentially targetable signaling pathway generates chemotherapy-resistant cancer cells

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Current research has identified a signaling pathway responsible for the generation of slowly proliferating cancer cells that are hard to eradicate via current treatments.

Maximum tolerated doses of gemcitabine

Maximum tolerated doses of gemcitabine

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How much more toxicity and myelosuppression has been associated with gemcitabine (Gemzar) when it is infused over periods longer than 30 minutes?

Combination therapy can reduce chance of recurrence from small HER2+ breast tumors

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Women with stage 1 HER2-positive breast tumors who received a combination of lower-intensity chemotherapy and a targeted drug following surgery were unlikely to suffer cancer recurrence within 3 years of treatment.

Stereotactic body radiation therapy (SBRT) plus chemotherapy improves survival among patients with stage 4 lung cancer

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Combining stereotactic body radiation therapy (SBRT) with a specific chemotherapy regimen more than doubled survival rates for certain patients with stage 4 lung cancer, according to recent research data.

Second-line ramucirumab delays disease progression in advanced colorectal cancer

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A combination treatment with of the drug ramucirumab and FOLFIRI chemotherapy provides a survival advantage over standard treatment with FOLFIRI alone for patients with advanced colorectal cancer, according to study data.

Long-term outcomes improved by combining bevacizumab with newer chemotherapy regimen for advanced colorectal cancer

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A phase III study of patients with metastatic colorectal cancer has indicated that FOLFOXIRI chemotherapy, in combination with bevacizumab, is superior to the standard FOLFIRI chemotherapy with bevacizumab.

Therapy dogs benefit adult patients with cancer receiving chemo, radiation

Therapy dogs benefit adult patients with cancer receiving chemo, radiation

Therapy dogs improve the emotional well-being of some patients with cancer who are undergoing concomitant chemotherapy and radiotherapy.

Effectiveness of drugs to prevent hepatitis among patients receiving chemotherapy

Use of the antiviral drug entecavir resulted in a lower incidence of hepatitis B virus (HBV)-related hepatitis and HBV reactivation among patients with lymphoma undergoing a certain type of chemotherapy.

Targeting mitochondrial enzyme may reduce cardiac effects from chemotherapy drug

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Investigators have identified two compounds that appear to block the cardiac damage caused by doxorubicin. Their report indicates that inhibiting the action of an enzyme key to the generation of cellular energy in mitochondria could prevent doxorubicin-induced damage to cardiac cells without reducing the drug's antitumor effects.

Importance of sequence in administering premeds with paclitaxel

Importance of sequence in administering premeds with paclitaxel

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In what sequence should you administer premedications prior to paclitaxel: Should the antihistamine be given first or the steroid?

SABCS: Novel breast cancer drugs show promise in early trials

SABCS: Novel breast cancer drugs show promise in early trials

Pictilisib and pembrolizumab may prolong survival for women with advanced breast cancer, according to data from preliminary studies.

Resistance exercise improves fatigue in patients with breast cancer receiving chemotherapy

Resistance exercise improves fatigue in patients with breast cancer receiving chemotherapy

Per a new study, resistant exercise decreased physical fatigue and maintained quality of life among patients with breast cancer receiving adjuvant chemotherapy.

New approach pioneered for treating HPV-related cervical cancer

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A drug typically used to treat infection of the retina in people with AIDS has been shown, for the first time, to sensitize cervical cancer to both chemotherapy and radiotherapy.

10 most popular complementary medicines may interact with cancer therapy

10 most popular complementary medicines may interact with cancer therapy

10 most asked about complementary medicines all may result in drug interactions with administered with chemotherapy, radiation, or prior to surgery.

Chemo- and immunotherapy combination is a promising treatment for pancreatic cancer

Chemo- and immunotherapy combination is a promising treatment for pancreatic cancer

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Pancreatic cancer may potentially be safely and effectively treated with immunochemotherapy, according to recent research from a preclinical study.

Chemotherapy after radiation slows progression of low-grade gliomas

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A chemotherapy regimen of procarbazine, lomustine (CCNU), and vincristine (PCV) administered after radiation therapy improved both progression-free survival and overall survival in adults with low-grade gliomas.

New research with scalp coolers may prevent chemotherapy-induced hair loss in more patients

New research with scalp coolers may prevent chemotherapy-induced hair loss in more patients

A new project is working on improving scalp cooling technology that prevents hair loss in cancer patients.

Irinotecan plus bevacizumab ups outcome for metastatic colorectal cancer (CRC)

Irinotecan plus bevacizumab ups outcome for metastatic colorectal cancer (CRC)

Findings show benefits compared with FOLFIRI for patients with untreated metastatic disease.

New treatment for retinoblastoma expected to save more eyes from cancer

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A new technique to treat retinoblastoma may help prevent eye loss, blindness, or death in children with advanced forms of the disease.

Benefit seen for adding trastuzumab to breast cancer chemotherapy

Benefit seen for adding trastuzumab to breast cancer chemotherapy

Herceptin in addition to chemotherapy boosts survival, reduces risk of cancer recurrence

Better adherence to guidelines for safe handling of antineoplastic drugs is needed

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Recommended safe handling practices for workers who administer antineoplastic drugs in health care settings are not always followed, according to a new study.

Landmark Medicare law had little impact on reducing chemotherapy cost

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Legislation passed in 2003 intended to slow the spiraling costs of drugs paid for by the federal government to treat Medicare patients has not proved to be a success.

Outcomes in nonsquamous lung cancer comparable with docetaxel or pemetrexed

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The first direct comparison of treating nonsquamous lung cancer with either pemetrexed or docetaxel in addition to cisplatin has shown that the two combinations achieve similar progression-free survival.

Importance of sequence in chemotherapy administration

Importance of sequence in chemotherapy administration

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Is sequencing important when administering chemotherapy on the same day?

High-dose radiotherapy doesn't offer survival benefit in mesothelioma

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Treatnent with high-dose radiotherapy after chemotherapy and surgery for malignant pleural mesothelioma does not achieve improvements in local relapse and overall survival, according to phase II trial data.

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