Should hydration be administered before all doses of cyclophosphamide (Cytoxan, Neosar) or just for high-dose Cytoxan?
Time to tumor growth proved to be the best metric for predicting overall survival in persons with metastatic colorectal cancer on bevacizumab.
A new study shows a significant correlation between poorer performance on neuropsychological tests and memory complaints in posttreatment, early-stage breast cancer patients—particularly those who have undergone combined chemotherapy and radiation.
Genetech announced results from CLL11, a Phase 3 study of obinutuzumab (GA101), comparing the combination of either obinutuzumab or Rituxan and chlorambucil to chlorambucil alone in chronic lymphocytic leukemia (CLL).
Gilead announced Phase 2 results for idelalisib, an oral inhibitor of PI3K delta in combination with rituximab for older patients with treatment-naïve chronic lymphocytic leukemia.
The FDA has approved Xofigo (radium Ra 223 dichloride; Bayer) for the treatment of symptomatic late-stage castration-resistant prostate cancer with bone metastases.
Although chemotherapy drugs can be lifesaving for patients with cancer, they can be toxic to nurses and other health care personnel who handle them. Nurses should protect themselves through the use of proper handling techniques. A regular review of safe chemotherapy drug handling practices and evaluation of the effectiveness of housekeeping...
The stem cell transplant regimen that was commonly used in the United States to treat advanced neuroblastoma in children appears to be more toxic than the equally effective regimen employed in Europe and Egypt, according to a new study.
Chemotherapy-induced nerve injury in the bone marrow is what impairs the regeneration of hematopoietic stem cells, leading to anemia.
Intraventricular chemotherapy to the brain improved symptoms and survival in persons with leptomeningeal carcinomatosis following lung cancer.
What is chemo brain, and what can be done for it?
High-fidelity simulation as a teaching modality for a chemotherapy administration practicum is safe and effective, readily accepted, and helps bridge the transition to the clinical environment, found research presented at the 38th ONS Annual Congress.
A program that educates non-chemotherapy provider nurses about how to administer and safely handle chemotherapy drugs improved their knowledge and skills, found research presented at the 38th ONS Annual Congress,
Combining a Wee1 protein inhibitor with the chemotherapy agent gemcitabine reduced sarcoma tumor volume more than did either drug alone.
Among patients with painful chemotherapy-induced peripheral neuropathy, use of the antidepressant drug duloxetine for 5 weeks resulted in a greater reduction in pain compared with placebo, according to a new study.
Packaging crystalline arsenic particles in a bubble of fat helps deliver the drug into lymphoma cells without damaging the ovaries.
How do certain chemotherapy agents make tumors more radiosensitive?
Cancer drug shortages led to treatment delays and changes, research complications, more medication errors and adverse outcomes, and higher costs.
A study has found that duloxetine effectively decreases pain for patients with chemotherapy-related peripheral neuropathy, especially for those who received the drug as initial treatment.
For elderly patients with metastatic colorectal cancer, certain geriatric scores were predictive of severe toxicity or unexpected hospitalization after fluorouracil-based chemotherapy with or without irinotecan.
A prospective clinical trial conducted in France found that children with low-risk retinoblastoma do not need adjuvant chemotherapy to prevent disease recurrence or metastasis.
IP chemo improves long-term survival in advanced disease versus intravenous therapy
Patients being treated with chemotherapy often complain about not being able to think clearly, connect thoughts, or concentrate on daily tasks. The complaint, often referred to as chemo-brain, is common, but its scientific cause has been difficult to pinpoint.
Persons who have undergone cytotoxic chemotherapy for certain cancers, notably non-Hodgkin lymphoma, may develop acute myeloid leukemia.
Scientists have developed a way to personalize chemotherapy drug selection for cancer patients by using cell lines created from their own tumors.
Is there an evidence-based booklet on cancer and diet available for patients undergoing chemotherapy? Is there any evidence that sugar causes cancer?
Intramuscular injections offer improved treatment adherence, ease in monitoring of adverse effects, and multiple administration sites.
Patients undergoing chemotherapy for hematologic cancers are at risk for this complication. The review can help you learn how to assess their risk.
What is the determining factor for preservation of fertility? Why can some women get pregnant after treatment and others cannot or do not? Is fertility preservation based on what chemotherapy one is receiving?
Scientists may be better able to predict which patients with colorectal cancer will respond to chemotherapy using a new mathematical model that measures the amount of stress required for a cancer cell to die without harming healthy tissue.
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