Chemotherapy

CDX2 Expression Predictive of Chemotherapy Benefit in Patients With Stage II Colorectal Cancer

By

Lack of CDX2 expression identified a subgroup of patients with high-risk stage II colon cancer who seemed to benefit from adjuvant chemotherapy.

Fosaprepiant May Not Provide Same Benefit as Aprepitant With 5-day Cisplatin

Fosaprepiant May Not Provide Same Benefit as Aprepitant With 5-day Cisplatin

By

Fosaprepitant may have a lower complete response rate than aprepitant when used in combination with a 5HT3 receptor antagonist.

Adjuvant Therapy Increases Survival in Small-Cell Lung Cancer

Adjuvant Therapy Increases Survival in Small-Cell Lung Cancer

Chemotherapy, with or without cranial irradiation, has been associated with improved survival versus surgery alone for patients with early-stage small-cell lung cancer (SCLC) undergoing resection.

Persistent Chemotherapy-induced Peripheral Neuropathy Symptoms Increase Risk of Falls and Altered Gait

Persistent Chemotherapy-induced Peripheral Neuropathy Symptoms Increase Risk of Falls and Altered Gait

By

Among women cancer survivors, 45% still experience symptoms of chemotherapy-induced peripheral neuropathy (CIPN) years after they have completed cancer treatment.

Volasertib Demonstrates Antitumor Activity in Patients With Ovarian Cancer

By

A study compared the effectiveness of volasertib versus chemotherapy for treatment of platinum-resistant or -refractory ovarian cancer.

In mCRPC, Docetaxel Active After Antiandrogen Therapy

By

A total of 40% of patients with mCRPC treated with docetaxel after abiraterone achieved at least a 50% reduction in PSA, according to a study presented at the 2016 Genitourinary Cancers Symposium.

Chemo May Reduce HRQoL, Sexual Function in Patients with Breast Cancer

Researchers observed significant changes in health-related quality of life (HRQoL), depression, and sexual function among patients with breast cancer receiving chemotherapy.

Type of Electromagnetic Field Therapy Improves Survival for Patients With Brain Tumor

By

Progression-free and overall survival were prolonged with electromagnetic field and chemotherapy maintenance therapy in patients with a brain tumor.

HNG Protects the Immune System and Preserves Fertility in Patients Receiving Chemotherapy

HNG Protects the Immune System and Preserves Fertility in Patients Receiving Chemotherapy

By

Humanin analogue protects both male germ cells, essential to fertility, and white blood cells, the soldiers in the body's defense system, during chemotherapy.

Early Chemotherapy Less Beneficial in Black Women With Breast Cancer

By

Black women with breast cancer treated with early chemotherapy fare worse than women of other minority groups.

Anthracycline-based Chemotherapy More Likely to Produce Neurotoxic Effects on Cognition in Breast Cancer Survivors

By

Anthracycline-based chemotherapy may have greater negative effects on some cognitive domains and brain network connections compared with nonanthracycline-based regimens.

Adding Carboplatin to Neoadjuvant Therapy for Triple-negative Early Breast Cancer Improves Disease-free Survival

Adding Carboplatin to Neoadjuvant Therapy for Triple-negative Early Breast Cancer Improves Disease-free Survival

By

Carboplatin added to anthracycline/taxane-based neoadjuvant chemotherapy significantly improved pathological complete response rates in patients with triple-negative breast cancer in two large phase IIb studies: GeparSixto and CALGB 40603. Researchers reported on disease-free survival for GeparSixto after median 35 months of observation at the 2015 San Antonio Breast Cancer Symposium.

Premenopausal Patients With High-risk Luminal A Breast Cancer Get No Benefit From Adjuvant Chemotherapy

Premenopausal Patients With High-risk Luminal A Breast Cancer Get No Benefit From Adjuvant Chemotherapy

By

Premenopausal women with luminal A subtype breast cancer had comparable 10-year disease-free survival rates regardless of whether they received adjuvant chemotherapy, according to data presented at the 2015 San Antonio Breast Cancer Symposium.

No Survival Benefit to Fourth Chemo Course in Younger Patients with AML

No Survival Benefit to Fourth Chemo Course in Younger Patients with AML

By

Although a fourth chemotherapy course may benefit younger patients with poor-risk acute myeloid leukemia, those with good and standard risk demonstrated little survival benefit from the additional course.

Clofarabine Inferior to Standard of Care in Older Patients Newly Diagnosed with AML

Clofarabine Inferior to Standard of Care in Older Patients Newly Diagnosed with AML

By

Single-agent clofarabine is was effective for older patients with newly diagnosed acute myeloid leukemia than standard therapy combined with daunorubicin and cytarabine.

Inotuzumab Ozogamicin + Low-Intensity Chemo Effective in Older Patients with ALL

Inotuzumab Ozogamicin + Low-Intensity Chemo Effective in Older Patients with ALL

By

Inotuzumab ozogamicin combined with low-intensity mini-hyper-CVD chemotherapy has demonstrated encouraging results in older patients with acute lymphoblastic leukemia, according to data from an ongoing study.

Peptide Reverses Temozolomide Resistance in Glioblastoma Cells

By

Scientists have discovered how to sensitize drug-resistant human glioblastoma cells to chemotherapy.

Investigational Immunotherapeutic Approach Increased Survival in Patients With Bladder Cancer

By

A novel immunotherapeutic approach improved outcomes for patients with advanced bladder cancer, according to a recent study.

Personalized Antinausea Regimens More Effective in Cancer Patients Receiving Emetogenic Chemotherapy

By

A personalized approach to treating nausea and vomiting, the most expected side effects of chemotherapy, is far more effective than the existing one-size-fits-all guidelines.

TESARO Announces Launch of Rolapitant for CINV

TESARO Announces Launch of Rolapitant for CINV

By

TESARO Inc has announced that rolapitant (Varubi), a neurokinin-1 (NK-1) receptor antagonist, is now available in the United States.

Study Findings Explain Why Chemotherapy May be Compromised in Patients With Pancreatic Cancer

By

Study findings may explain why chemotherapy drugs such as gemcitabine are not effective for many patients with pancreatic cancer, and perhaps point to new approaches to treatment including enhancing gemcitabine's ability to stop tumor growth.

Breast Cancer Marker CK5 Also Marks Cisplatin-Resistant Ovarian Cancer

By

The protein cytokeratin 5 (CK5), known to be a marker of poor prognosis in patients with breast cancer, also marks ovarian cancers likely to be resistant to the common chemotherapy cisplatin.

Gene Expression Test Can Lead to More Effective Treatment Decisions In Patients With Invasive Lobular Carcinoma (ILC) Breast Cancer

By

Most patients with invasive lobular carcinoma (ILC) breast cancer could be treated with hormones alone and not with chemotherapy.

Ramosetron vs. Ondansetron for Prevention of CINV Assessed

Ramosetron vs. Ondansetron for Prevention of CINV Assessed

By

Ramosetron plus dexamethasone and aprepitant is as effective and tolerable as ondansetron.

Intensity-Modulated Radiation Lessens Side Effects for Lung Cancer Patients

Intensity-Modulated Radiation Lessens Side Effects for Lung Cancer Patients

By

An analysis of an international, cooperative-led trial of patients with locally advanced NSCLC has shown that those who received IMRT had less severe lung toxicity and were able to better tolerate their chemotherapy, compared with patients who received 3-D CRT.

High-Dose Chemo and Stem Cell Transplantation Results in Long-Term Survival for Patients With Amyloidosis

By

Patients with light-chain amyloidosis who are treated with high-dose chemotherapy and autologous stem cell transplantation have the greatest success for long-term survival.

Targeted Chemotherapy Shows Early Signs of Slowing Tumor Growth With Less Toxicity

By

Surviving neuroblastoma as a child can come with just as many challenges as the cancer itself. But a team of surgeons is in the nascent stages of developing a more targeted method for delivering chemotherapy, with lower toxicity.

First Targeted Treatment for Small Cell Lung Cancer Shows Promise

First Targeted Treatment for Small Cell Lung Cancer Shows Promise

By

Remarkable early results were reported from a phase 1 trial of a novel agent, rovalpituzumab tesirine (Rova-T, or S16LD6.5), in 79 patients with SCLC who had progressed after first- or second-line therapy.

Hormonal Therapy May Prevent Ovarian Failure and Preserve Fertility in Patients With Breast Cancer

By

Young women undergoing chemotherapy for breast cancer may be more likely to remain fertile if they also receive hormonal treatment, according to new research presented at ECC2015.

Handling Closed System Device-Incompatible Chemotherapy Agents

Handling Closed System Device-Incompatible Chemotherapy Agents

By

How can accidental exposure/leaks when handling chemotherapy drugs that incompatible with the closed system device (CSD) be prevented?

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs