Chemotherapy

Risk of Bladder Recurrence Reduced With Chemotherapy Flush After Tumor Resection

Risk of Bladder Recurrence Reduced With Chemotherapy Flush After Tumor Resection

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Flushing the bladder with a chemotherapeutic agent after tumor resection significantly reduced recurrence rates of bladder cancer.

No Improvement in KRAS-Mutation Lung Cancer With MEK Inhibitor Plus Chemotherapy

No Improvement in KRAS-Mutation Lung Cancer With MEK Inhibitor Plus Chemotherapy

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A combination treatment of mitogen-activated protein kinase MEK inhibitor and chemotherapy did not improve progression-free survival in patients with advanced lung cancer caused by a KRAS gene mutation.

Significant Reductions in CLABSIs Achieved With Daily Chlorhexidine Bathing in Oncology Population

Significant Reductions in CLABSIs Achieved With Daily Chlorhexidine Bathing in Oncology Population

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Daily CHG bathing can safely reduce CLABSIs in oncology patients with central lines, with small variations in efficacy of the practice due to differences in patient population, work processes, and team engagement.

Cisplatin Plus Standard-of-Care Regimen Reduced Tumors in Advanced Pancreatic Cancer

Cisplatin Plus Standard-of-Care Regimen Reduced Tumors in Advanced Pancreatic Cancer

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Cisplatin plus standard-of-care gemcitabine/nab-paclitaxel improved tumor shrinkage in patients with metastatic pancreatic cancer, according to a study by the HonorHealth Research Institute and the Translational Genomics Research Institute.

Research Shows Temozolomide Has Potential to Increase Depression

Research Shows Temozolomide Has Potential to Increase Depression

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Temozolomide, an antimitotic chemotherapy used to treat brain cancer, demonstrated the potential to increase depression in a mouse model.

Standardized Assessment Tool Prevents Chemotherapy-Induced Neurotoxicity

Standardized Assessment Tool Prevents Chemotherapy-Induced Neurotoxicity

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Standardized tool improved efficiency and thoroughness of patient assessment and documentation of neurotoxicity caused by high-dose cytarabine.

Education and Coaching Are Necessary to Treat Oropharyngeal Cancers After Chemoradiotherapy

Education and Coaching Are Necessary to Treat Oropharyngeal Cancers After Chemoradiotherapy

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A literature review noted improvements in quality of life after patients were coached and educated following radiotherapy for HPV-associated oropharyngeal cancers.

New Closed System Drug Transfer Device Can Reduce Nurse Exposure to Antineoplastic Hazardous Drugs

New Closed System Drug Transfer Device Can Reduce Nurse Exposure to Antineoplastic Hazardous Drugs

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A new CSTD significantly reduced surface contamination during a simulated antineoplastic hazardous drug administration when compared to baseline.

Standardized Process for Assessing Chemotherapy Appointments Improves Patient Wait Times

Standardized Process for Assessing Chemotherapy Appointments Improves Patient Wait Times

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Prior assessment of patients and review of infusion orders by an interprofessional ACE team can significantly reduce patient wait times, prevent same-day inefficiencies, and reduce wasted chemotherapy doses.

Rolapitant Eases CINV in Patients Receiving Highly, Moderately Emetogenic Chemotherapy

Rolapitant Eases CINV in Patients Receiving Highly, Moderately Emetogenic Chemotherapy

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Long-acting NK-1 receptor antagonist rolapitant demonstrates significant efficacy in managing CINV in patients receiving HEC or MEC for cancer.

Follow-up Surgery Not Needed When Breast Cancer Responds to Neoadjuvant Chemotherapy

Follow-up Surgery Not Needed When Breast Cancer Responds to Neoadjuvant Chemotherapy

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Women with triple-negative or HER2-positive breast cancer who achieve a pathologic complete response from neoadjuvant chemotherapy may be able to avoid follow-up breast or lymph node surgery.

Online Module Seeks to Educate Nurses on the Identification and Management of Hypersensitivity Reactions to Chemotherapy

Online Module Seeks to Educate Nurses on the Identification and Management of Hypersensitivity Reactions to Chemotherapy

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Hypersensitivity reactions in patients receiving chemotherapy are not common, but their serious nature requires that oncology nurses be able to manage them when they occur.

Short-Term Fasting Alleviates Toxic Effects, High Glucose Levels Associated With Chemotherapy

Short-Term Fasting Alleviates Toxic Effects, High Glucose Levels Associated With Chemotherapy

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Short-term fasting may alleviate toxic effects caused by high blood glucose levels associated with common cancer drugs.

High-Dose Vitamin C Infusions Increase Cancer Cell Sensitivity to Chemotherapy, Radiation

High-Dose Vitamin C Infusions Increase Cancer Cell Sensitivity to Chemotherapy, Radiation

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Regular infusions of high doses of vitamin C safely increased cancer cell sensitivity to treatment in patients with brain and lung cancers.

Exercise Improves Coping While Undergoing Chemotherapy for Advanced GI Cancer

Exercise Improves Coping While Undergoing Chemotherapy for Advanced GI Cancer

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Exercise helps patients with gastrointestinal cancer undergoing chemotherapy cope with their disease and treatment.

Everolimus Found to Improve Chemotherapy-Induced Infertility in Preclinical Research

Everolimus Found to Improve Chemotherapy-Induced Infertility in Preclinical Research

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A study using a mouse model to investigate the effect of adding everolimus to cyclophosphamide to slow tumor growth found the drug also preserves fertility.

Regorafenib Improves Quality-adjusted Survival in Sarcoma

Regorafenib Improves Quality-adjusted Survival in Sarcoma

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In patients with soft tissue sarcoma pretreated with doxorubicin, treatment with regorafenib significantly reduced the risk of progression symptoms or toxicity.

Chemotherapy or VBT Improve Survival in Uterine Papillary Serous Carcinoma

Chemotherapy or VBT Improve Survival in Uterine Papillary Serous Carcinoma

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Use of chemotherapy or vaginal brachytherapy (VBT) may improve survival among patients with early-stage uterine papillary serous carcinoma.

Research Shows Vitamin B3 Reduces Pain From Chemotherapy-Induced Peripheral Neuropathy

Research Shows Vitamin B3 Reduces Pain From Chemotherapy-Induced Peripheral Neuropathy

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Nicotinamide riboside, a type of B3 vitamin, was shown to prevent chemotherapy-induced peripheral neuropathy in an animal-model study.

Skeletal Muscle Mass, Composition Is Predictive of Treatment-Related Toxicity in Breast Cancer

Skeletal Muscle Mass, Composition Is Predictive of Treatment-Related Toxicity in Breast Cancer

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Quantity and quality of skeletal muscle is a more accurate measure for determining dose and of potential treatment-related toxicity in patients receiving chemotherapy for early-stage breast cancer.

Ginger Extract Raises Antioxidant Levels in Patients Undergoing Chemotherapy

Ginger Extract Raises Antioxidant Levels in Patients Undergoing Chemotherapy

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Supplemental ginger before and during treatment raises antioxidant levels in patients undergoing chemotherapy.

Regional Chemotherapy Technique May Help Prevent Amputations

Regional Chemotherapy Technique May Help Prevent Amputations

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Researchers indicate that it may be possible lower amputation rates by nearly 80% in patients with extremity sarcomas.

SCLC: No Benefit from Pravastatin When Added to First-line Chemo

SCLC: No Benefit from Pravastatin When Added to First-line Chemo

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The addition of pravastatin to first-line chemotherapy did not improve overall survival or progression-free survival in patients with small-cell lung cancer.

Patients With a Recurrence Score of 11 to 25 May Not Benefit from Chemo

Patients With a Recurrence Score of 11 to 25 May Not Benefit from Chemo

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Patients with hormone receptor-positive, HER2-negative, axillary lymph node-negative breast cancer who have a recurrence score of 11 to 25 may not benefit from chemotherapy.

Single Chemotherapy Dose Informs Treatment Strategy for Advanced Laryngeal Cancer

Single Chemotherapy Dose Informs Treatment Strategy for Advanced Laryngeal Cancer

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A new approach in which patients receive a single dose of chemotherapy may greatly improve the laryngeal cancer survival rate.

Metronomic Chemotherapy: Improved Tumor Blood Supply Leads to Better Treatment

Metronomic Chemotherapy: Improved Tumor Blood Supply Leads to Better Treatment

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The mechanism of metronomic chemotherapy: Improved tumor blood supply leads to better treatment .

Metabolic Syndrome More Likely After Platinum-Based Chemotherapy for Testicular Cancer

Metabolic Syndrome More Likely After Platinum-Based Chemotherapy for Testicular Cancer

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Survivors of testicular cancer are more likely to develop metabolic syndrome after platinum-based chemotherapy.

Timing of Chemotherapy Infusion Affects Inflammatory Response to Chemotherapy

Timing of Chemotherapy Infusion Affects Inflammatory Response to Chemotherapy

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Light/dark cycle of the day influences inflammatory processes in various tissues in the body, potentially affecting risk factors in patients with cancer.

Neoadjuvant Chemotherapy May Benefit African-American Women with Breast Cancer

Neoadjuvant Chemotherapy May Benefit African-American Women with Breast Cancer

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Administering chemotherapy to African-American women with breast cancer prior to surgery may help improve their survival.

Chemo May Be Overused Among Young, Middle-aged Adults With Colon Cancer

Chemo May Be Overused Among Young, Middle-aged Adults With Colon Cancer

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Chemotherapy may be overused among young and middle-aged adults with colon cancer, with the addition of adjuvant chemotherapy not resulting in a matched survival benefit.

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