Chemotherapy

New combination could make cancer more sensitive to chemotherapy

New combination could make cancer more sensitive to chemotherapy

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Combining chemotherapy with new drugs that target a protein that helps cancer cells withstand chemotherapy could improve treatment.

For patients with terminal cancer, chemotherapy does not improve quality of life

For patients with terminal cancer, chemotherapy does not improve quality of life

Chemotherapy administered to patients with cancer who are near death does not improve quality of life.

Chemotherapy-related decline in cognitive function correlated with biomarkers

Chemotherapy-related decline in cognitive function correlated with biomarkers

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Research indicates a connection between chemo-related cognitive function decline and molecular immune biomarkers, genetic aging, and neurotransmitter markers.

The impact of 5-hydroxytryptamine-receptor antagonists on chemotherapy treatment adherence, treatment delay, and nausea and vomiting

The impact of 5-hydroxytryptamine-receptor antagonists on chemotherapy treatment adherence, treatment delay, and nausea and vomiting

[Cancer Management and Research] This research examines the incidence of chemotherapy-induced nausea/vomiting (CINV) and treatment delay among patients receiving palonosetron versus other 5-hydroxytryptamine receptor antagonist (5-HT3 RA) antiemetics.

Chemotherapy dosages in overweight or obese patients with ovarian cancer

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Overweight or obese patients with ovarian cancer are typically given lower per-pound chemotherapy doses to reduce toxic side effects, which could impact their survival chances.

Hydration regimens for cisplatin

Hydration regimens for cisplatin

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Is there evidence to support adding potassium magnesium and mannitol to the hydration regimens for cisplatin?

Stress hormones could undermine breast cancer therapy

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The stress hormones often used to treat the side effects of chemotherapy could have the side effect of making effective cancer drugs fail sooner in some women with breast cancer, according to new research.

Addition of aprepitant may improve vomiting control in patients receiving oxaliplatin

Addition of aprepitant may improve vomiting control in patients receiving oxaliplatin

A three-drug combination antiemetic therapy including aprepitant or fosaprepitant improved the prevention rate of nausea and vomiting.

Chemotherapy may be the preferred option for some patients with advanced prostate cancer

Chemotherapy may be the preferred option for some patients with advanced prostate cancer

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In a small clinical trial, scientists found that men with advanced prostate cancer and detection of androgen receptor splice variant-7 (AR-V7) respond to chemotherapy just as well as men who lack the variant.

Low-quality evidence found to support use of cannabinoids for CINV

Low-quality evidence found to support use of cannabinoids for CINV

Moderate-quality evidence to support the use of cannabinoids for the treatment of chronic pain.

Multimodality treatment for metastatic lung cancer with surgery may improve survival

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Patients with an advanced form of metastatic non-small cell lung cancer (NSCLC) may benefit from surgical resection of all or part of the lung if combined with chemotherapy and radiation therapy.

Optimal nurse:patient ratio for patients on IL-2

Optimal nurse:patient ratio for patients on IL-2

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What is the best practice recommendation for nurse-to-patient ratio for patients receiving IL-2?

Combining targeted drug with chemotherapy prolongs life for patients with B-cell lymphoma

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The combination of ibrutinib and chemotherapy (bendamustine and rituximab [BR]) was found to reduce the risk of death by nearly 80% in patients with previously treated CLL or SLL.

Immunotherapy drug improves survival for common form of lung cancer

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Individuals with squamous non-small cell lung cancer (NSCLC) fared better when receiving nivolumab when compared to those receiving more standard chemotherapy, according to a recent clinical trial.

Intravenous nutrition source could reduce side effects of chemotherapy

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The side effects caused by potent chemotherapy regimens could possibly be considerably lessened by use of an intravenous nutrition source.

Biomarker may boost ovarian cancer response to chemotherapy

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Researchers have identified a molecule that may play a central role in chemotherapy resistance in patients with the most common ovarian cancer.

Chemotherapy before surgery benefits patients with advanced ovarian cancer

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Women with advanced ovarian cancer have fewer side effects and tend to have a better quality of life if given chemotherapy before surgery.

Managing capecitabine-associated mucositis

Managing capecitabine-associated mucositis

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How should severe mucositis from capecitabine (Xeloda) be managed?

Exercise throughout chemotherapy reduces cognitive impairment, inflammation

Exercise throughout chemotherapy reduces cognitive impairment, inflammation

Patients with cancer who exercise throughout chemotherapy had reduced chronic inflammation and cognitive impairment.

Optimal Sequencing for Chemotherapy and Radium 223 for Prostate Cancer Under Debate

Optimal Sequencing for Chemotherapy and Radium 223 for Prostate Cancer Under Debate

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When is chemotherapy or radium 223 the optimal treatment for men with advanced prostate cancer?

Treatment factors examined that are associated with improved survival in oral cavity cancer

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Neck dissection of lymph nodes and treatment at academic or research institutions are both associated with improved survival for patients with stages I and II oral cavity squamous cell cancer, according to recent research.

Efficacy of Cathflo at suggested volume

Efficacy of Cathflo at suggested volume

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Given reservoir volume and catheter length, 2.2 mL of Cathflo does not seem to be enough volume to reach the tip, thus the sheath/clot. Are there any reports of using larger volumes?

Cancer scan could remove need for radiotherapy in cured patients

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PET scan usage for patients with early stage Hodgkin lymphoma could potentially help them avoid unneeded radiotherapy.

Personal protective equipment (PPE) guidelines for handling monoclonal antibodies (MABs)

Personal protective equipment (PPE) guidelines for handling monoclonal antibodies (MABs)

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Is there a new consensus about wearing personal protective equipment (PPE) when handling monoclonal antibodies (MABs) for infusion?

Ad-REIC Gene Therapy: Promising Results in a Patient with Metastatic CRPC Following Chemotherapy

Ad-REIC Gene Therapy: Promising Results in a Patient with Metastatic CRPC Following Chemotherapy

[Clinical Medicine Insights] In this case study, a 63-year-old man with metastatic castration-resistant prostate cancer (CRPC) was successfully treated for two years with in situ gene therapy using an adenovirus vector carrying the human REIC/Dkk‑3 gene.

Chemobrain is a real cognitive effect

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Chemotherapy, which can cause an inability to concentrate, is measurable effect related to cancer treatment.

Changes in cancer epigenome implicated in chemotherapy resistance and lymphoma relapse

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New research indicate that malfunctioning genes are only partly to blame for why treatment that was effective ultimately fails in many patients with the most common form of non-Hodgkin lymphoma.

Purity of herbal supplements

Purity of herbal supplements

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The purity of herbal supplements has been questioned. How should one advise patients interested in using these products?

Transitioning High-Dose AML Chemo to Outpatient Setting Improves Quality of Life

Transitioning High-Dose AML Chemo to Outpatient Setting Improves Quality of Life

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Transitioning a long-standing intensive chemotherapy regimen for acute myeloid leukemia (AML) to the outpatient setting is safe and feasible.

New treatment options discovered for colorectal tumors

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Scientists have discovered that a chemotherapy drug already used to treat leukemia could prevent and control the growth of colorectal tumors.

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