Chemotherapy

Management of chemotherapy-induced nausea and vomiting (CINV)

Management of chemotherapy-induced nausea and vomiting (CINV)

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Could a medication indicated for nausea and vomiting in pregnancy resolve the same symptoms in patients undergoing chemotherapy?

Herpes zoster vaccine effective with chemotherapy

Herpes zoster vaccine effective with chemotherapy

Vaccine is effective even among older adults who subsequently undergo chemotherapy.

Shingles vaccine found to be safe and effective after chemotherapy

Shingles vaccine found to be safe and effective after chemotherapy

The herpes zoster vaccine continues to be effective in protecting older adults against shingles, even after they undergo chemotherapy, according to a recent study.

Overall survival in advanced NSCLC increased with less toxic chemotherapy

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A 10-year study shows that increased availability of better systemic chemotherapies and targeted therapies for patients with advanced non-small cell lung cancer coincides with increased usage of these therapies.

Managing follicular lymphoma

Managing follicular lymphoma

Changes in how follicular lymphoma is managed have led to substantial improvement in prognosis and over all survival for patients with the disease.

DNA origami can deliver targeted cancer drugs

DNA origami can deliver targeted cancer drugs

Scientists have shown that DNA origami can be used for the targeted delivery of cancer drugs to tumor cells in mice.

Everolimus does not affect survival rate for advanced liver cancer

Everolimus does not affect survival rate for advanced liver cancer

No considerable survival difference found between patients receiving everolimus and those receiving a placebo.

Combination treatment improves recurrence and survival in ovarian cancer

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A new combination of medications for treatment of recurrent ovarian cancer showed improved response rates, increased the rate of tumor shrinkage, and prolonged the time until cancers recurred

Benefits of trastuzumab outweigh the risk of harm in advanced breast cancer

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A new systematic review shows that treatment with the breast cancer drug trastuzumab is associated with prolonged survival in women with advanced breast cancer, but the risk of developing heart problems also increases.

Neuroendocrine cancer halted by chemo-radionuclide therapy

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Advanced cancer of the neuroendocrine system can lead to dismal prognoses, but a novel therapy is packing a punch by uniting powerful radionuclide treatment and chemotherapy drugs.

Study Compares Outcomes for Treatments of Uncommon Eye Cancer

Study Compares Outcomes for Treatments of Uncommon Eye Cancer

Treatment with selumetinib resulted in improved progression-free survival time and tumor response rate compared with chemotherapy, but no improvement was seen in overall survival. Furthermore, the modest improvement in clinical outcomes was accompanied by a high rate of adverse effects.

Orientation class eases patient anxiety at first chemotherapy visit

Orientation class eases patient anxiety at first chemotherapy visit

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Oncology nurses reduce a patient's anxious response to chemo visits through supportive, relationship-based education that provides an overview of chemotherapy.

Fasting may protect against immune-related effects of chemotherapy

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Periodic fasting may combat both chemotherapy-induced changes in immune cell function by replenishing stem cells in the blood; these findings suggest that fasting may provide benefits for cancer patients.

Small-molecule drugs cross the blood-brain barrier

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A synthetic peptide carrier is a potential delivery vehicle for chemotherapy drugs for brain cancer and for other neurologic medications, according to new research.

Promising results from new therapy for pancreatic cancer

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A clinical trial showed that the new drug MM-398, given in combination with 5-flourouracil (5-FU) and leucovorin, produced a significant overall survival rate in patients with advanced pancreatic cancer.

Treating breast cancer drug resistance via a malaria drug

Treating breast cancer drug resistance via a malaria drug

An inexpensive malaria drug could be the answer for some women who are not responding to their cancer treatment, according to a promising but preliminary animal study.

Prostate cancer treatment can delay chemotherapy

Prostate cancer treatment can delay chemotherapy

Researchers have developed a new technique to combat metastatic prostate cancer (which is called castration-resistant), which could delay the start of chemotherapy.

Post-chemo cognitive depreciation linked to brain activity changes

Post-chemo cognitive depreciation linked to brain activity changes

For patients undergoing chemotherapy for breast cancer, cognitive complaints after treatment may be associated with changes in brain activity, according to a study.

New drug for non-Hodgkin lymphoma and chronic leukemia succeeds in phase I

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A new chemotherapy drug being investigated for its potency against two types of cancer was found to be effective in about one-third of the participants in a phase I study.

Optimal dosing for TMZ: 1 hour prior to RT versus bedtime

Optimal dosing for TMZ: 1 hour prior to RT versus bedtime

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Is there a difference in dosing (1 hour prior to radiotherapy vs bedtime) with temozolomide plus radiotherapy for glioblastoma multiforme?

ASCO: Olaparib and cediranib combo promising for recurrent ovarian cancer

ASCO: Olaparib and cediranib combo promising for recurrent ovarian cancer

For women with recurrent platinum-sensitive ovarian cancer, the combination of the PARP inhibitor olaparib and the anti-angiogenesis drug cediranib is more effective than olaparib alone.

ASCO: Ramucirumab extends survival for NSC lung cancer

ASCO: Ramucirumab extends survival for NSC lung cancer

For patients with non-small-cell lung cancer who have relapsed after initial treatment, the addition of the anti-angiogenesis drug ramucirumab to standard docetaxel chemotherapy extends survival.

Trial uncovers potential dangers of chemotherapy regimen for bladder cancer

Trial uncovers potential dangers of chemotherapy regimen for bladder cancer

Patients with muscle-invasive bladder cancer often benefit from chemotherapy before surgery to remove the tumor, but a test of one regimen by researchers at Fox Chase Cancer Center was halted when too many people experienced serious side effects such as heart attacks and blood clots in the legs and lungs.

Chemotherapy first may be helpful in rectal cancer

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A new phase II study finds that if chemotherapy is offered before radiation and surgery, more patients will be able to tolerate it and receive a full regimen of treatment.

Docetaxel + ADT ups survival in metastatic prostate cancer

Docetaxel + ADT ups survival in metastatic prostate cancer

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Upfront standard androgen deprivation therapy plus six cycles of docetaxel significantly improves overall survival compared with ADT alone in men with metastatic hormone-sensitive prostate cancer.

New way to predict response to chemotherapy in triple-negative breast cancer

New way to predict response to chemotherapy in triple-negative breast cancer

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The presence of tumor-infiltrating lymphocytes ahead of treatment may help predict response to platinum-based chemotherapy in women with triple-negative breast cancer, according to a new study.

Ginger extract improves chemotherapy-induced nausea, vomiting

Ginger extract improves chemotherapy-induced nausea, vomiting

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A ginger extract, 6-gingerol, improves chemotherapy-induced nausea and vomiting (CINV), according to findings from a phase 2 randomized trial presented at the 2014 Annual ASCO Meeting.

Combination treatment shows early promise for metastatic pancreatic ductal cancer

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A combination of several small doses of an investigational radioimmunotherapy and the chemotherapy gemcitabine had superior outcomes compared with radioimmunotherapy alone in patients with metastatic pancreatic ductal cancer.

Novel target identified for chemotherapy-resistant leukemia cells

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By targeting a particular receptor, chemotherapy-resistant cancer cells can be killed in an acute form of childhood leukemia, according to new research.

Gene expression profiling weighs heavily in decisions for breast cancer patients yet poorly understood

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Gene expression profiling tests play a critical role when women with early-stage breast cancer decide whether to receive chemotherapy, but many patients don't understand what the test results mean.

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