Chemotherapy and Drug Information

Everolimus Found to Improve Chemotherapy-Induced Infertility in Preclinical Research

Everolimus Found to Improve Chemotherapy-Induced Infertility in Preclinical Research

A study using a mouse model to investigate the effect of adding everolimus to cyclophosphamide to slow tumor growth found the drug also preserves fertility.

Regorafenib Improves Quality-adjusted Survival in Sarcoma

Regorafenib Improves Quality-adjusted Survival in Sarcoma

In patients with soft tissue sarcoma pretreated with doxorubicin, treatment with regorafenib significantly reduced the risk of progression symptoms or toxicity.

Chemotherapy or VBT Improve Survival in Uterine Papillary Serous Carcinoma

Chemotherapy or VBT Improve Survival in Uterine Papillary Serous Carcinoma

Use of chemotherapy or vaginal brachytherapy (VBT) may improve survival among patients with early-stage uterine papillary serous carcinoma.

Immunosuppressor Inhibits Metabolic Pathway in Breast Cancer, Kills Cancer Cells

Immunosuppressor Inhibits Metabolic Pathway in Breast Cancer, Kills Cancer Cells

Leflunomide, an immunosuppressor FDA-approved for rheumatoid arthritis, is effective against breast cancer in mouse study.

Research Shows Vitamin B3 Reduces Pain From Chemotherapy-Induced Peripheral Neuropathy

Research Shows Vitamin B3 Reduces Pain From Chemotherapy-Induced Peripheral Neuropathy

Nicotinamide riboside, a type of B3 vitamin, was shown to prevent chemotherapy-induced peripheral neuropathy in an animal-model study.

ASCO Issues Adjuvant Bisphosphonate in Breast Cancer Guideline

ASCO Issues Adjuvant Bisphosphonate in Breast Cancer Guideline

Zoledronic acid and clodranate are the recommended bisphosphonates for the adjuvant treatment of postmenopausal patients with breast cancer.

Skeletal Muscle Mass, Composition Is Predictive of Treatment-Related Toxicity in Breast Cancer

Skeletal Muscle Mass, Composition Is Predictive of Treatment-Related Toxicity in Breast Cancer

Quantity and quality of skeletal muscle is a more accurate measure for determining dose and of potential treatment-related toxicity in patients receiving chemotherapy for early-stage breast cancer.

Letermovir Reduces CMV Infection, Improves Survival After Stem Cell Transplantation

Letermovir Reduces CMV Infection, Improves Survival After Stem Cell Transplantation

A novel agent, letermovir, reduced incidence of CMV in patients undergoing stem cell transplantation for hematologic malignancies.

Patients with Lung Cancer Do Not Benefit from Statins

Patients with Lung Cancer Do Not Benefit from Statins

Statins provide no benefits, or adverse effects, in patients with lung cancer, according to a phase 3 trial.

Kinase Inhibitors: Managing Adverse Effects in the Treatment of Metastatic Melanoma

Kinase Inhibitors: Managing Adverse Effects in the Treatment of Metastatic Melanoma

Despite their efficacy in metastatic melanoma, KIs include risk of serious side effects in patients. This overview explains the effects and management recommendations for 4 agents used to treat metastatic melanoma.

Stat Consult Slideshows

Fluorouracil (5-FU)

This slideshow reviews fluorouracil (5-FU), indicated for palliative treatment of breast cancer, colorectal cancer, gastric cancer, and carcinoma of the pancreas; also adjuvant treatment of colorectal cancer.

Netupitant/Palonosetron (Akynzeo)

This slideshow reviews netupitant/palonosetron (Akynzeo), indicated for prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of cancer chemotherapy.

Bevacizumab (Avastin) - cervical cancer

This slideshow reviews bevacizumab (Avastin), indicated for cervical cancer, in combination with paclitaxel and cisplatin or paclitaxel and topotecan in persistent, recurrent, or metastatic disease.

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