Chemotherapy and Drug Information

Addition of aprepitant may improve vomiting control in patients receiving oxaliplatin

Addition of aprepitant may improve vomiting control in patients receiving oxaliplatin

A three-drug combination antiemetic therapy including aprepitant or fosaprepitant improved the prevention rate of nausea and vomiting.

Chemotherapy may be the preferred option for some patients with advanced prostate cancer

In a small clinical trial, scientists found that men with advanced prostate cancer and detection of androgen receptor splice variant-7 (AR-V7) respond to chemotherapy just as well as men who lack the variant.

Low-quality evidence found to support use of cannabinoids for CINV

Low-quality evidence found to support use of cannabinoids for CINV

Moderate-quality evidence to support the use of cannabinoids for the treatment of chronic pain.

Multimodality treatment for metastatic lung cancer with surgery may improve survival

Patients with an advanced form of metastatic non-small cell lung cancer (NSCLC) may benefit from surgical resection of all or part of the lung if combined with chemotherapy and radiation therapy.

Optimal nurse:patient ratio for patients on IL-2

Optimal nurse:patient ratio for patients on IL-2

What is the best practice recommendation for nurse-to-patient ratio for patients receiving IL-2?

Next-generation ALK-inhibitor brigatinib promising against NSCLC

Clinical trial results showed good performance employing the investigational drug brigatinib against ALK-positive non-small cell lung cancer (NSCLC).

Combining targeted drug with chemotherapy prolongs life for patients with B-cell lymphoma

The combination of ibrutinib and chemotherapy (bendamustine and rituximab [BR]) was found to reduce the risk of death by nearly 80% in patients with previously treated CLL or SLL.

Immunotherapy drug improves survival for common form of lung cancer

Individuals with squamous non-small cell lung cancer (NSCLC) fared better when receiving nivolumab when compared to those receiving more standard chemotherapy, according to a recent clinical trial.

Intravenous nutrition source could reduce side effects of chemotherapy

The side effects caused by potent chemotherapy regimens could possibly be considerably lessened by use of an intravenous nutrition source.

Biomarker may boost ovarian cancer response to chemotherapy

Researchers have identified a molecule that may play a central role in chemotherapy resistance in patients with the most common ovarian cancer.

Stat Consult Slideshows

Fluorouracil (5-FU)

This slideshow reviews fluorouracil (5-FU), indicated for palliative treatment of breast cancer, colorectal cancer, gastric cancer, and carcinoma of the pancreas; also adjuvant treatment of colorectal cancer.

Netupitant/Palonosetron (Akynzeo)

This slideshow reviews netupitant/palonosetron (Akynzeo), indicated for prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of cancer chemotherapy.

Bevacizumab (Avastin) - cervical cancer

This slideshow reviews bevacizumab (Avastin), indicated for cervical cancer, in combination with paclitaxel and cisplatin or paclitaxel and topotecan in persistent, recurrent, or metastatic disease.

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