Chemotherapy and Drug Information

Vulnerability to Infection Increases for Breast Cancer Survivors Treated With Chemotherapy

Chemotherapy for breast cancer can affect the body's ability to ward off common illnesses.

First-line Afatinib Benefits Lung Cancer Patients With Brain Metastases

For patients with non-small cell lung cancer who have EGFR mutations and brain metastases, progression-free survival was improved with afatinib compared to chemotherapy.

Nab-paclitaxel Increases Complete Response Rate in Invasive Breast Cancer

Replacing paclitaxel with nab-paclitaxel, followed by neoadjuvant epirubicin and cyclophosphamide, proved beneficial for patients with invasive breast cancer.

Data Analysis Shows 8-week Chemoradiotherapy-to-Surgery Timeline Achieves Optimal Tumor Response

Overall survival was best and resection of residual locally advanced rectal tumors most successful when surgery occurred at precisely 8 weeks, or 56 days, after completion of chemoradiotherapy.

CDX2 Expression Predictive of Chemotherapy Benefit in Patients With Stage II Colorectal Cancer

Lack of CDX2 expression identified a subgroup of patients with high-risk stage II colon cancer who seemed to benefit from adjuvant chemotherapy.

Development of Microtubulin Inhibitor Is a Potential Lead to Novel Biologic Therapy

Gatastatin, an inhibitor specific for γ-tubulin, known to be overexpressed in some cancer cells, has been identified and holds potential for the development of anticancer agents.

Fosaprepiant May Not Provide Same Benefit as Aprepitant With 5-day Cisplatin

Fosaprepiant May Not Provide Same Benefit as Aprepitant With 5-day Cisplatin

Fosaprepitant may have a lower complete response rate than aprepitant when used in combination with a 5HT3 receptor antagonist.

Reduced Toxicity, Similar Efficacy Achieved With Novel Regimen for Advanced Rectal Cancer

No difference in local efficacy was found between two treatment regimens for colorectal cancer: short-course (5-day) radiation followed by consolidation chemotherapy before surgery and standard 5-week chemoradiation.

Understanding Drug Naming Nomenclature

Understanding Drug Naming Nomenclature

Why do the antibody drugs have such long names?

Adjuvant Therapy Increases Survival in Small-Cell Lung Cancer

Adjuvant Therapy Increases Survival in Small-Cell Lung Cancer

Chemotherapy, with or without cranial irradiation, has been associated with improved survival versus surgery alone for patients with early-stage small-cell lung cancer (SCLC) undergoing resection.

Stat Consult Slideshows

Fluorouracil (5-FU)

This slideshow reviews fluorouracil (5-FU), indicated for palliative treatment of breast cancer, colorectal cancer, gastric cancer, and carcinoma of the pancreas; also adjuvant treatment of colorectal cancer.

Netupitant/Palonosetron (Akynzeo)

This slideshow reviews netupitant/palonosetron (Akynzeo), indicated for prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of cancer chemotherapy.

Bevacizumab (Avastin) - cervical cancer

This slideshow reviews bevacizumab (Avastin), indicated for cervical cancer, in combination with paclitaxel and cisplatin or paclitaxel and topotecan in persistent, recurrent, or metastatic disease.

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