Chemotherapy and Drug Information

Nivolumab Provides Better Long-Term Efficacy Compared With Docetaxel in NSCLC

Nivolumab Provides Better Long-Term Efficacy Compared With Docetaxel in NSCLC

Two phase 3 studies reveal the clinical benefit, safety profile, and overall survival of nivolumab and docetaxel for patients with squamous and nonsquamous NSCLC.

Pursuing Aggressive Treatment Impacts Breast Cancer Patients' Employment

Pursuing Aggressive Treatment Impacts Breast Cancer Patients' Employment

Investigators surveyed more than 3000 patients with breast cancer and found that disruptions to employment and work stoppage were greater in those who underwent more aggressive treatment options.

Nurse Survey Identifies Adverse Events Related to Handling Chemotherapy

Nurse Survey Identifies Adverse Events Related to Handling Chemotherapy

Using a 4-question survey, investigators determined oncology nurses' perception of their risks in handling and administering cytotoxic chemotherapy to patients.

De-escalated Radiation Therapy Improves Quality of Life in Throat Cancer

De-escalated Radiation Therapy Improves Quality of Life in Throat Cancer

Aggressive de-escalation of chemoradiation after surgery in patients with HPV-associated OPSCC led to similar disease control and improved quality of life and safety profile compared with historical controls, according to data presented at the ASTRO 59th Annual Meeting.

Radiation Prior to Chemotherapy Prolongs Progression-Free Survival in NSCLC

Radiation Prior to Chemotherapy Prolongs Progression-Free Survival in NSCLC

Researchers present findings of a phase 2 study that compared PFS when SBRT is administered prior to maintenance chemotherapy in patients with limited metastatic NSCLC vs chemotherapy alone. Data was presented at ASTRO 59th Annual Meeting.

Lorazepam Plus Haloperidol Improves Agitation in Cancer-Related Delirium

Lorazepam Plus Haloperidol Improves Agitation in Cancer-Related Delirium

A double-blind study compared the effectiveness of lorazepam plus haloperidol with haloperidol alone in reducing agitation in patients with advanced cancer.

Treating Intractable Hiccups in Advanced Cancer, Palliative Care Setting

Treating Intractable Hiccups in Advanced Cancer, Palliative Care Setting

Intractable hiccups can be especially problematic in the advanced cancer and palliative care settings. Dr Thompson, an oncology pharmacist, reviews options for effective medical management of this condition.

FDA Approves Gemtuzumab Ozogamicin for CD-33 Positive Acute Myeloid Leukemia

FDA Approves Gemtuzumab Ozogamicin for CD-33 Positive Acute Myeloid Leukemia

Gemtuzumab ozogamicin (Mylotarg) was granted US FDA approval for the treatment of relapsed or refractory CD-33 positive AML in patients ages 2 years and older and newly diagnosed CD-33 positive AML in adult patients.

Progression-Free Survival in CLL Prolonged With Maintenance Lenalidomide

Progression-Free Survival in CLL Prolonged With Maintenance Lenalidomide

Lenalidomide reduced the relative risk of disease progression in a clinical trial of patients with chronic lymphocytic leukemia who did not achieve MRD negative disease state after first-line chemoimmunotherapy.

Progression-Free, Overall Survival in Liposarcoma Improved With Eribulin vs Dacarbazine

Progression-Free, Overall Survival in Liposarcoma Improved With Eribulin vs Dacarbazine

Comparison study shows significantly improved overall survival and progression-free survival in patients with advanced LPS treated with eribulin vs dacarbazine.

Stat Consult Slideshows

Fluorouracil (5-FU)

This slideshow reviews fluorouracil (5-FU), indicated for palliative treatment of breast cancer, colorectal cancer, gastric cancer, and carcinoma of the pancreas; also adjuvant treatment of colorectal cancer.

Netupitant/Palonosetron (Akynzeo)

This slideshow reviews netupitant/palonosetron (Akynzeo), indicated for prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of cancer chemotherapy.

Bevacizumab (Avastin) - cervical cancer

This slideshow reviews bevacizumab (Avastin), indicated for cervical cancer, in combination with paclitaxel and cisplatin or paclitaxel and topotecan in persistent, recurrent, or metastatic disease.

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