Chemotherapy-induced Nausea And Vomiting (CINV)
This study compared the effectiveness of olazapine, palonosetron, and ondansetron in the treatment of CINV in patients receiving HSCT who are refractory to prophylactic antiemetic agents.
Antiemetic overuse is prevalent among patients with cancer receiving emetogenic chemotherapy and leads to unnecessary spending.
Adding rolapitant to a 5-HT3 receptor antagonist and dexamethasone significantly improved the prevention of CINV in patients with GI and CRC cancers receiving highly or moderately emetogenic chemotherapy.
The Multinational Association of Supportive Care in Cancer and the European Society for Medical Oncology updated their 2009 consensus recommendations for the prevention of acute CINV in pediatric patients with cancer.
Some of our patients receive olanzapine (Zyprexa) as an antiemetic. Is this a typical use of this drug?
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