Adjuvant chemotherapy administered during and after radiotherapy is feasible for the treatment of patients with high-risk endometrial cancer despite an increased risk of toxicities compared with radiotherapy alone.
First results from the phase 3 CRITICS study found no significant difference in overall survival between postoperative chemotherapy and chemoradiotherapy in patients with resectable gastric cancer, according to a study presented at the ASCO 2016 Annual Meeting.
A phase 3 noninferiority study has found that in patients with nonoperable locally advanced squamous cell cancer of the head and neck, concurrent chemoradiotherapy remains the standard treatment, according to results presented at the ASCO 2016 Annual Meeting.
Chemoradiotherapy Showed No Survival Benefit Over Chemotherapy in Locally Advanced Pancreatic CancerMay 24, 2016
Researchers discovered no survival benefit of chemoradiotherapy over chemotherapy in treating locally advanced pancreatic cancer in the LAP01 Randomized Clinical Trial.
Adding radiotherapy to chemotherapy and surgery reduced the number of local disease recurrences but did not affect distant recurrences or survival.
Survival rates are not increased and the likelihood of receiving a full course of radiation is decreased for patients with locally advanced head and neck cancer who receive IC rather than the standard treatment of CRT.
Adding chemotherapy to radiation therapy improves survival among elderly patients—age 71 to 79 years—with head and neck cancers, low comorbidity scores, and advanced-stage disease.
Overall survival was best and resection of residual locally advanced rectal tumors most successful when surgery occurred at precisely 8 weeks, or 56 days, after completion of chemoradiotherapy.
No difference in local efficacy was found between two treatment regimens for colorectal cancer: short-course (5-day) radiation followed by consolidation chemotherapy before surgery and standard 5-week chemoradiation.
Concurrent Chemoradiotherapy Using Paclitaxel Plus Cisplatin in the Treatment of Elderly Patients With Esophageal CancerNovember 27, 2015
The purpose of this research was to examine both efficiency and safety of concurrent chemoradiotherapy (CCRT) using paclitaxel combined with cisplatin in elderly esophageal cancer patients.
Increased survival for chemoradiotherapy versus chemotherapy in limited-stage, small-cell lung cancer was observed in a recent study.
Breast cancer and chemobrain: Stress of diagnosis can impair cognitive function before chemotherapy is startedMay 05, 2015
Milder cognitive defects displayed by breast cancer patient even before the initiation of chemotherapy may be attributable to disease-related posttraumatic stress, new study data indicates.
Capecitabine-induced leukocytoclastic vasculitis under neoadjuvant chemotherapy for locally advanced colorectal cancerApril 29, 2015
[Journal of Gastrointestinal Oncology] The article examines a case of capecitabine-induced leukocytoclastic vasculitis in a patient with locally advanced rectal cancer under curative neoadjuvant concurrent chemoradiation using capecitabine.
Patients treated with definitive concurrent chemotherapy and radiation therapy for stage III non-small cell lung cancer (NSCLC) showed better overall survival when treated at experienced facilities.
Radiation therapy with concurrent paclitaxel chemotherapy after surgery can be effective to treat patients with high-risk endometrial cancer, according to new research.
Results from a clinical trial of a new treatment for glioblastoma suggest that researchers may have found a new approach to treating this aggressive brain tumor.
FOLFIRINOX chemotherapy plus chemoradiation helped make resection possible in locally advanced pancreatic cancer.
How do certain chemotherapy agents make tumors more radiosensitive?
Adding erlotinib did not increase treatment toxicity in squamous cell carcinoma of the head and neck, but it also did not improve survival.
Long-term follow-up results from two clinical trials have confirmed substantially longer survival for certain patients with anaplastic oligodendrogliomas if they are treated with a combination of chemotherapy and radiation therapy instead of radiation alone.
News about pertuzumab injection (Perjeta); ondansetron (Zofran); carfilzomib (Kyprolis); Therascreen KRAS RGQ PCR Kit; Prostate Health Index (phi); and Prepopik
Oncologists at M.D. Anderson Cancer Center found the key to screening for pancreatic cancer lies in the interpretation of preoperative CT scans.
Induction chemotherapy plus conformal radiation therapy improves event-free survival.
Gemcitabine/oxaliplatin induction followed by chemoradiotherapy improves survival, resectability.
Survival improved for elderly patients with non-small cell lung cancer who had combined chemotherapy and radiotherapy rather than radiotherapy alone.
Significantly better overall survival exists for patients with esophageal, esophagogastric-junction cancer.
Six cycles of higher-dose chemotherapy, not the standard eight cycles or a lower-dose variant, should be the treatment of choice for advanced Hodgkin.
An interactive educational event demonstrated the importance of safe-handling technique of chemotherapy drugs in an approach that bridged generational learning differences.
BMI appears to have no bearing on surgical complications or survival after esophagectomy following neoadjuvant chemoradiotherapy for adenocarcinoma.
Locoregional control of muscle-invasive bladder cancer improved without additional toxicity.
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- Combination of Gemcitabine and New CHK1 Inhibitor Is Effective in Soft Tissue Sarcomas
- Alcohol Consumption, Particularly White Wine, Associated With Increased Risk of Melanoma
- LIVESTRONG Exercise Program Improves QoL in Cancer Survivors
- Exercise is as Effective in Treating Metastatic Prostate Cancer as Medication
- Walnut Consumption Changes Gut Microbiome, Decreases Growth of Colon Cancer in Mice
- Vaccine Enters Phase I Study for Safety and Effectiveness in Multiple Myeloma
- Timing Chemotherapy Administration to Circadian Rhythm Improves Drug Effectiveness
- New Therapy Blocks Breast Cancer Cells From Entering and Hiding in Bone Marrow to Form Latent Metastases
- Assessment of Stromal Features in DCIS Requires Robustness
- Profile of Tivantinib and its Potential in the Treatment of Hepatocellular Carcinoma: the evidence to date
- RANKL Inhibition May Represent Promising Breast Cancer Prevention Strategy
- Bi-allelic Inactivation Common in BRCA1 and BRCA Breast Cancers
- In HER2+ Breast Cancer, Higher TIL Levels Associated With Improved OS
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