Checkpoint Inhibitors

Immune Checkpoint Inhibitors: A Review of Side Effects, Their Causes and Incidence

Immune Checkpoint Inhibitors: A Review of Side Effects, Their Causes and Incidence

By

A multicenter research team determined the incidence and type of fatal toxic effects associated with immune checkpoint inhibitors.

Preexisting Rheumatoid Disease Not a Deterrent to Immune Checkpoint Inhibitor Therapy

Preexisting Rheumatoid Disease Not a Deterrent to Immune Checkpoint Inhibitor Therapy

By

Investigators reviewed clinical data from patients with cancer and pre-existing rheumatic disease treated with ipilimumab, nivolumab, or pembrolizumab.

Approach and Management of Checkpoint Inhibitor-related Immune Hepatitis

Approach and Management of Checkpoint Inhibitor-related Immune Hepatitis

[Journal of Gastrointestinal Oncology] A review of diagnostic parameters and management modalities for checkpoint inhibitor-induced hepatic toxicity is presented.

Epigenetic Modulation, Checkpoint Inhibition Showed Potential in HER2 Breast Cancer

Epigenetic Modulation, Checkpoint Inhibition Showed Potential in HER2 Breast Cancer

By

Using a mouse model of HER2+ breast cancer, researchers tested the efficiency of combined epigenetic modulation and checkpoint inhibition using the histone deacetylase inhibitor ENT and antibodies for 2 checkpoint inhibitor proteins. These findings were presented at the 2017 SABCS.

Early Recognition of Checkpoint Inhibitor-Related Pneumonitis Improves Outcomes

Early Recognition of Checkpoint Inhibitor-Related Pneumonitis Improves Outcomes

By

As the use of checkpoint inhibitors increases in many types of cancer, oncology nurses need to learn to recognize the signs and symptoms of pneumonitis, a rare but life-threatening adverse effect of these agents.

Use of Checkpoint Inhibitors in Urothelial Carcinoma

Use of Checkpoint Inhibitors in Urothelial Carcinoma

By

Studies presented in the last year demonstrated a revolutionary role for immune checkpoint inhibitors in the treatment of urothelial carcinoma.

ABX May Impact Efficacy of Checkpoint Inhibitors in RCC

ABX May Impact Efficacy of Checkpoint Inhibitors in RCC

By

Patients with advanced kidney cancer received broad-spectrum antibiotics less than a month before initiating immune checkpoint inhibitor therapy.

Using the Immune System to Improve the Efficacy of Radiation Therapy

Using the Immune System to Improve the Efficacy of Radiation Therapy

By

A healthy immune system may be the key to effective radiation therapy for cancer patients.

Antibody-drug Conjugates Show Potential in Breast Cancer

By

Research in mouse models has identified molecules that can bind to cancer cells and induce apoptosis.

Sign Up for Free e-newsletters



Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs