Cancer Screening

Gut microbiome analysis improved noninvasive colorectal cancer screening

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Analysis of the gut microbiome more successfully distinguished healthy persons from those with precancerous adenomatous polyps and those with invasive colorectal cancer compared with assessment of clinical risk factors and fecal occult blood testing, according to recently published data.

Mammography benefits women older than 75 years

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Mammography-detected breast cancer is associated with a shift to earlier stage diagnosis in older women, subsequently reducing the rate of more advanced, difficult-to-treat cases. Researchers said the findings lend support to regular mammography screening in women age 75 years and older.

Computer tomography (CT) lung screening benefits far outweigh patient anxiety

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Anxiety regarding inconclusive cancer screening test results among some patients is real and is only natural. However, as evidenced by a recent study, the incidence and effects of anxiety associated with false positive or other results of CT lung cancer screening exams are far less than claimed by some in the medical community.

Full Explanation Reduces Seniors' Anxiety about Lung Cancer Screening

Full Explanation Reduces Seniors' Anxiety about Lung Cancer Screening

A new study of participants in the NLST found evidence that men and women age 55 to 74 who had an abnormal finding on a lung cancer screening test did not experience more anxiety or reduced quality of life than did those who were screened and found to be cancer-free.

Interactive phone messages aid cancer screening

Interactive phone messages aid cancer screening

Underserved Latina patients view interactive voice response (IVR) messages as an acceptable strategy to promote cancer screening, according to a study.

Colonoscopy withdrawal times linked to polyp detection rates

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Longer withdrawal times during a colonoscopy correlate with a higher rate of polyp detection, according to new research.

Cervical cancer protection greater with HPV screening than with cytology-based screening

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Primary screening for HPV provides 60% to 70% greater protection against invasive cervical cancer than the cytology-based (smear test) screening currently used.

Screening guidelines may miss 10% of colon cancers

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For people with a family history of adenomas, up to 10% of colorectal cancers could be missed when current national screening guidelines are followed.

Risk of overdiagnosis in cancer screenings is not being explained

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A survey finds that most patients are not being told about the possibility of overdiagnosis and overtreatment as a result of cancer screenings.

Caregivers may want to nix cancer screening for patients with dementia

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Many people caring for a family member with dementia want to put an end to screening the person for cancer as the dementia progresses, and are relieved when health care providers bring up the topic, according to the findings of a small focus-group study.

New screening approach quickly identifies small proteins unique to melanoma cells

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A new streamlined method rapidly identifies genetic changes in small protein fragments unique to melanoma cancer cells.

Twice as many lung cancers detected by CT as by X-ray at initial screening

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Centers in the United States can achieve a 20% reduction in lung cancer mortality with low-dose computed tomography (LDCT) versus chest X-ray (CXR) screening that was previously reported by the National Lung Screening Trial (NLST).

Screening reveals potential alternative drug therapies for neuroblastoma

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A new genomic approach for screening compounds has identified a compound that causes neuroblastoma cells to differentiate. This new strategy screens for compounds that could inhibit tumor growth by causing cancer cells to differentiate.

Agent Orange exposure linked to life-threatening prostate cancer

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Exposure to Agent Orange has been linked to lethal forms of prostate cancer among US veterans by a new analysis.

Screening for ovarian cancer uses neighboring cells

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Pioneering biophotonics technology is the first screening method to detect the early presence of ovarian cancer in humans

Radiation can be reduced while maintaining high quality in CT colonoscopy

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High-quality CT colonoscopy diagnostic images can be maintained while reducing the radiation dose, according to a new study.

Digital rectal examinations remain important in screening for prostate cancer

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The digital rectal examination is an important screening test that can discover prostate cancer that a PSA test may not, despite the higher sensitivity of the PSA test.

Trio of biomarkers may help to identify kidney cancer in early stages

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A new immunoassay that tests for the presence of three biomarkers appears to be a valid screening method for the early detection of malignant kidney cancer. The immunoassay measured the levels of three potential biomarkers for kidney cancer.

Screening colonoscopy significantly reduces the risk of advanced colorectal cancer

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A new study adds support to current medical recommendations stating that screening colonoscopy substantially reduced the likelihood of advanced CRC in either the right or left side of the colon being diagnosed in an average-risk adult.

Colon cancer screening doubles with use of electronic health records

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Researchers used electronic EHRs to identify patients in a health care cooperative who were not screened regularly for cancer of the colon and rectum, and to encourage them to be screened.

New test uses Pap test fluid to detect ovarian and endometrial cancers

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A pilot study of the PapGene test, which relies on genomic sequencing of cancer-specific mutations, accurately detected all 24 (100%) endometrial cancers and nine of 22 (41%) ovarian cancers.

Cancer screening goals not being met by general population

Cancer screening goals not being met by general population

Cancer survivors meet U.S. Healthy People 2010 goals for all screening except cervical cancer.

Decision aids sway more patients to undergo colon cancer screening

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Providing information tools to help people decide whether to undergo colorectal cancer screening leads to them being more likely to request the procedure.

Annual report highlights 2012 cancer advances

The American Society of Clinical Oncology has released a nearly 100-page report detailing the year's most significant developments in cancer.

Scatter radiation from mammography does not increase risk of cancer

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The radiation dose to areas of the body near the breast during mammography is negligible, or very low, and does not result in an increased risk of cancer, according to a new study.

Tomosynthesis sharpens digital mammography results

Adding three-dimensional breast imaging to standard digital mammography increases diagnostic accuracy and reduces false-positive recall rates.

Other tests may be effective for rescreening after initial colonoscopy is negative

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A new modeling study has found that people who undergo colonoscopy at age 50 years in which no precancerous polyps are found can be rescreened at age 60 years with one of three alternative methods, rather than undergoing colonoscopy every 10 years.

Novel breast screening technology increases diagnostic accuracy

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Adding three-dimensional imaging to standard digital mammography significantly increases the diagnostic accuracy of radiologists while reducing the rate of false positive recalls.

High mortality persists for black women with breast cancer

Black women have the highest death rate from breast cancer of all racial and ethnic groups, and are 40% more likely to die of the disease than are white women, according to a new report from the CDC.

Study suggests 10-year colonoscopy rescreen not needed after first negative result

It may be reasonable to use methods other than colonoscopy to rescreen people who had negative results on their first screening colonoscopy.

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