Cancer In The Elderly
A data analysis reveals the likelihood of older women with to ER-positive DCIS to initiate and adhere to adjuvant tamoxifen or aromatase inhibitors.
Cognitive function is an important factor when considering oral therapy as an option for cancer treatment, particularly for elderly patients with cancer.
Patients with cancer incur significant out-of-pocket costs before their Medicare drug benefits activate, and due to those costs, many patients with CML delayed starting their treatment.
Nearly one-third of older patients with cancer are exposed to severe drug interactions and potentially inappropriate medications.
A deficit-accumulation frailty index constructed from a comprehensive geriatric assessment may predict outcomes in older patients with cancer.
Cognitive decline associated with adjuvant chemotherapy was more likely to occur in older patients, particularly those whose treatment included docetaxel.
Improved cancer detection and advances in treatment mean larger numbers of older cancer patients are becoming survivors, combined with demographic trends. But older patients are underrepresented in clinical trials.
The incidence of oropharyngeal squamous cell carcinoma is increasing among older patients residing in the United States, likely due to the increase in HPV-associated malignancies.
Screening for colorectal cancer (CRC) is not widely used by Americans age 75 years and older, even though some patients are healthy and may benefit.
A group of researchers sought to examine the physical functioning of patients with breast cancer, in various age brackets, who were enrolled in the Tamoxifen Exemestane Adjuvant Multinational (TEAM) phase III trial.
The proportion of older patients with comorbidities receiving treatment for metastatic colorectal cancer (mCRC) has increased over the last 2 decades despite the overall percentage of older adults being treated remaining low.
Likelihood of other chronic conditions will stress health care system in next two decades, as more patients with cancer live longer.
Many Older Women With Early Stage Breast Cancer Are Susceptible to Functional Decline After Starting TreatmentJuly 05, 2016
Approximately 20% of older women with stage I-III breast cancer lost the ability to complete some basic tasks of independent living within 1 year of starting treatment. However, an assessment tool can identify those women at greatest risk of posttreatment functional decline.
More accurate modeling of cancer, which affects the elderly more than younger populations, could speed breakthroughs in research. Therefore, research on immunotherapy for cancer should include obese and older mice.
Adding Temozolomide to Radiotherapy Improves Survival in Elderly Patients With Newly Diagnosed GlioblastomaJune 06, 2016
The addition of temozolomide to standard short-course radiation therapy significantly improved both overall and progression-free survival in elderly patients with newly diagnosed glioblastoma, results from the first study to test this combination in this age group concluded in a plenary presentation at the ASCO 2016 Annual Meeting.
When added to the CHOP regimen, alemtuzumab increases remission rates in elderly patients with peripheral T cell lymphoma, final analysis of the international ACT-2 phase 3 trial presented at the ASCO 2016 Annual Meeting has shown.
Results from this study showed that 5-year survival for older patients after surgery for lung cancer is favorable. Based on these results, surgeons might be better equipped to individualize care for this older population.
Cancer increases the risk for some health issues beyond the normal risks that accompany aging. This increased risk could be due to decreased physical activity and increased stress associated with cancer diagnosis and treatment.
Socioeconomic status and features of physical health rather than tumor characteristics were associated with symptoms of depression among long-term survivors of colorectal cancer.
Men age 67 years or older with prostate cancer were 37% more likely to be hospitalized for noncancer reasons after their cancer diagnosis than before their diagnosis.
A working knowledge of frailty, multimorbidity, and geriatric syndromes, as well as self-awareness of and sensitivity to ageism are key skills for oncology navigators caring for older patients.
Older patients who undergo surgery to treat cancer are more likely to experience injuries and other health issues such as falling down, breaking bones, dehydration, bed sores, failure to thrive, and delirium. The risks are particularly notable in patients who undergo major abdominal surgery.
Unmet health information needs, even nearly a decade after a cancer diagnosis, were a key finding of a study of the needs of cancer survivors who are at least 9 years beyond an initial diagnosis.
Adding chemotherapy to radiation therapy improves survival among elderly patients—age 71 to 79 years—with head and neck cancers, low comorbidity scores, and advanced-stage disease.
Outcomes Are Comparable With Treatment Allocation Based on CGA or Performance Status and Age in Elderly Patients with NSCLCFebruary 18, 2016
Treatment allocation based on comprehensive geriatric assessment (CGA) did not improve treatment failure free survival or overall survival, but treatment toxicity was slightly reduced, in elderly patients with NSCLC.
The rate of non-recommended screening is 15.7 percent in those 65 years and older.
Elderly patients can safely undergo thyroid surgery with careful preoperative screening. The procedure was found to be no more dangerous in patients older than 65 years than in those ages 21 to 35 years.
The longest survival time was observed for primary debulking surgery coupled with chemotherapy in an optimal timeframe.
Single-agent clofarabine is was effective for older patients with newly diagnosed acute myeloid leukemia than standard therapy combined with daunorubicin and cytarabine.
Inotuzumab ozogamicin combined with low-intensity mini-hyper-CVD chemotherapy has demonstrated encouraging results in older patients with acute lymphoblastic leukemia, according to data from an ongoing study.
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- Olaratumab in Combo With Doxorubicin Approved for Soft Tissue Sarcoma
- Overall Benefits of Vaporized Nicotine Products Outweigh Harms, Says International Panel of Experts
- Nurse Residency Programs Can Impact Oncology Nursing Practice, Outcomes
- Implementing a Distress Screening Process for Cancer Patients
- Initiating Palliative Care in the Emergency Department
- Exercise is as Effective in Treating Metastatic Prostate Cancer as Medication
- Adherence to Tamoxifen, AIs Among Older Women is Low, Study Shows
- Replacing Neoadjuvant CRT with Multiagent Chemo Not Recommended for Rectal Cancer
- Study Identifies Factors Associated With Infection-related Complications in ALL
- Immune Checkpoint-Related Neurotoxicity May Be More Common During Combination Treatment
- New Recommendations for Secondary Prevention of Cervical Cancer
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