Cancer In The Elderly

Gero-Oncology: Preparing for the Coming Wave of Elderly Cancer Patients

Gero-Oncology: Preparing for the Coming Wave of Elderly Cancer Patients

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A growing proportion of cancer patients are elderly—creating a demographic shift with important implications for cancer care, including radiotherapy. Integrating geriatric care into oncology nursing has never been more important.

Adherence to WCRF/AICR Diet Linked to Lower Cancer Risk Among Older Adults

Adherence to WCRF/AICR Diet Linked to Lower Cancer Risk Among Older Adults

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Adherence to World Cancer Research Fund (WCRF)/American Institute for Cancer Research (AICR) dietary recommendations improves cancer risks. In this study, researchers determined whether adherence to these recommendations provides the same benefits for older persons.

Adherence to Tamoxifen, AIs Among Older Women is Low, Study Shows

Adherence to Tamoxifen, AIs Among Older Women is Low, Study Shows

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A data analysis reveals the likelihood of older women with to ER-positive DCIS to initiate and adhere to adjuvant tamoxifen or aromatase inhibitors.

Cognitive Function Impacts Oral Cancer Therapy Adherence

Cognitive Function Impacts Oral Cancer Therapy Adherence

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Cognitive function is an important factor when considering oral therapy as an option for cancer treatment, particularly for elderly patients with cancer.

Cost of TKI Therapy Leads to Delay in Treatment for Many Patients With Leukemia

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Patients with cancer incur significant out-of-pocket costs before their Medicare drug benefits activate, and due to those costs, many patients with CML delayed starting their treatment.

Nearly One-Third of Older Patients With Cancer Are Exposed to Severe Drug Interactions

Nearly One-Third of Older Patients With Cancer Are Exposed to Severe Drug Interactions

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Nearly one-third of older patients with cancer are exposed to severe drug interactions and potentially inappropriate medications.

Frailty Index May Predict Outcomes in Older Patients

Frailty Index May Predict Outcomes in Older Patients

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A deficit-accumulation frailty index constructed from a comprehensive geriatric assessment may predict outcomes in older patients with cancer.

Cognitive Impairment Common With Adjuvant Therapy in Older Patients With Early Stage Breast Cancer

Cognitive Impairment Common With Adjuvant Therapy in Older Patients With Early Stage Breast Cancer

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Cognitive decline associated with adjuvant chemotherapy was more likely to occur in older patients, particularly those whose treatment included docetaxel.

Increasing Numbers of Older Cancer Survivors Challenge Clinical Trial Participant Criteria

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Improved cancer detection and advances in treatment mean larger numbers of older cancer patients are becoming survivors, combined with demographic trends. But older patients are underrepresented in clinical trials.

Incidence of Oropharyngeal Cancer Increasing Among Older Patients

Incidence of Oropharyngeal Cancer Increasing Among Older Patients

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The incidence of oropharyngeal squamous cell carcinoma is increasing among older patients residing in the United States, likely due to the increase in HPV-associated malignancies.

Elderly Patients Often Not Up-to-Date on Screening for Colorectal Cancer

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Screening for colorectal cancer (CRC) is not widely used by Americans age 75 years and older, even though some patients are healthy and may benefit.

Surgery and Adjuvant Hormonal Therapy Less Effective for Older Patients With Breast Cancer

Surgery and Adjuvant Hormonal Therapy Less Effective for Older Patients With Breast Cancer

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A group of researchers sought to examine the physical functioning of patients with breast cancer, in various age brackets, who were enrolled in the Tamoxifen Exemestane Adjuvant Multinational (TEAM) phase III trial.

More Older Patients With Comorbidities Are Receiving Therapy for mCRC

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The proportion of older patients with comorbidities receiving treatment for metastatic colorectal cancer (mCRC) has increased over the last 2 decades despite the overall percentage of older adults being treated remaining low.

U.S. Cancer Survivors Aging, Battling Other Chronic Conditions

U.S. Cancer Survivors Aging, Battling Other Chronic Conditions

Likelihood of other chronic conditions will stress health care system in next two decades, as more patients with cancer live longer.

Many Older Women With Early Stage Breast Cancer Are Susceptible to Functional Decline After Starting Treatment

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Approximately 20% of older women with stage I-III breast cancer lost the ability to complete some basic tasks of independent living within 1 year of starting treatment. However, an assessment tool can identify those women at greatest risk of posttreatment functional decline.

Animal Models for Cancer Immunotherapy Research Should Reflect Older and Obese Patient Populations

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More accurate modeling of cancer, which affects the elderly more than younger populations, could speed breakthroughs in research. Therefore, research on immunotherapy for cancer should include obese and older mice.

Adding Temozolomide to Radiotherapy Improves Survival in Elderly Patients With Newly Diagnosed Glioblastoma

Adding Temozolomide to Radiotherapy Improves Survival in Elderly Patients With Newly Diagnosed Glioblastoma

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The addition of temozolomide to standard short-course radiation therapy significantly improved both overall and progression-free survival in elderly patients with newly diagnosed glioblastoma, results from the first study to test this combination in this age group concluded in a plenary presentation at the ASCO 2016 Annual Meeting.

Alemtuzumab + CHOP for Peripheral T Cell Lymphoma: Higher Remission, But Not Survival

Alemtuzumab + CHOP for Peripheral T Cell Lymphoma: Higher Remission, But Not Survival

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When added to the CHOP regimen, alemtuzumab increases remission rates in elderly patients with peripheral T cell lymphoma, final analysis of the international ACT-2 phase 3 trial presented at the ASCO 2016 Annual Meeting has shown.

Older Patients With Lung Cancer Experience High Survival After Surgery

Older Patients With Lung Cancer Experience High Survival After Surgery

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Results from this study showed that 5-year survival for older patients after surgery for lung cancer is favorable. Based on these results, surgeons might be better equipped to individualize care for this older population.

Cancer Might Drive Physical and Mental Health Issues in Aging Patients

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Cancer increases the risk for some health issues beyond the normal risks that accompany aging. This increased risk could be due to decreased physical activity and increased stress associated with cancer diagnosis and treatment.

SES, Physical Health Features Linked to Depression Among CRC Survivors

SES, Physical Health Features Linked to Depression Among CRC Survivors

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Socioeconomic status and features of physical health rather than tumor characteristics were associated with symptoms of depression among long-term survivors of colorectal cancer.

Noncancer-related Hospitalizations Increase After Prostate Cancer Diagnoses in Elderly Men

Noncancer-related Hospitalizations Increase After Prostate Cancer Diagnoses in Elderly Men

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Men age 67 years or older with prostate cancer were 37% more likely to be hospitalized for noncancer reasons after their cancer diagnosis than before their diagnosis.

Navigating the Older Patient Through Cancer Care

Navigating the Older Patient Through Cancer Care

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A working knowledge of frailty, multimorbidity, and geriatric syndromes, as well as self-awareness of and sensitivity to ageism are key skills for oncology navigators caring for older patients.

Certain Cancer Surgeries Increase Risks for Injuries and Other Health Concerns in Older Patients

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Older patients who undergo surgery to treat cancer are more likely to experience injuries and other health issues such as falling down, breaking bones, dehydration, bed sores, failure to thrive, and delirium. The risks are particularly notable in patients who undergo major abdominal surgery.

Survivorship Information Is Scarce for Longer-term Survivors of Cancer

Survivorship Information Is Scarce for Longer-term Survivors of Cancer

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Unmet health information needs, even nearly a decade after a cancer diagnosis, were a key finding of a study of the needs of cancer survivors who are at least 9 years beyond an initial diagnosis.

Elderly Patients With Head and Neck Cancer Benefit From Chemoradiation

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Adding chemotherapy to radiation therapy improves survival among elderly patients—age 71 to 79 years—with head and neck cancers, low comorbidity scores, and advanced-stage disease.

Outcomes Are Comparable With Treatment Allocation Based on CGA or Performance Status and Age in Elderly Patients with NSCLC

Outcomes Are Comparable With Treatment Allocation Based on CGA or Performance Status and Age in Elderly Patients with NSCLC

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Treatment allocation based on comprehensive geriatric assessment (CGA) did not improve treatment failure free survival or overall survival, but treatment toxicity was slightly reduced, in elderly patients with NSCLC.

Many Seniors Receiving Unneeded Mammography and Prostate Cancer Screening

Many Seniors Receiving Unneeded Mammography and Prostate Cancer Screening

The rate of non-recommended screening is 15.7 percent in those 65 years and older.

Older Patients Can Safely Undergo Thyroid Surgery

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Elderly patients can safely undergo thyroid surgery with careful preoperative screening. The procedure was found to be no more dangerous in patients older than 65 years than in those ages 21 to 35 years.

Surgery and Chemo Combo Optimal for Elderly With Advanced Ovarian Cancer

Surgery and Chemo Combo Optimal for Elderly With Advanced Ovarian Cancer

The longest survival time was observed for primary debulking surgery coupled with chemotherapy in an optimal timeframe.

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