Breast Cancer

Breast Cancer Treatment-Related Financial Burden Greater for Black vs White Women

Breast Cancer Treatment-Related Financial Burden Greater for Black vs White Women

In a study that evaluated outcomes for younger, working age women with breast cancer, researchers identified differences in cancer-related financial adverse events in black women vs white women.

Spotlight on Triptorelin in the Treatment of Premenopausal Women with Early-Stage Breast Cancer

Spotlight on Triptorelin in the Treatment of Premenopausal Women with Early-Stage Breast Cancer

[Breast Cancer: Targets and Therapy] Researchers present a review of the LHRH agonist triptorelin and the use of this agent to induce chemical castration in estrogen-sensitive breast cancer tumors in younger women.

Combination Effective as First-Line Therapy in Advanced ER-Positive HER2-Negative Breast Cancer

Combination Effective as First-Line Therapy in Advanced ER-Positive HER2-Negative Breast Cancer

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In this open label phase 2 BOLERO-4 study, researchers evaluated the effect of everolimus plus endocrine therapy on progression-free survival.

In Older Women With Breast Cancer QoL May Predict 10-Year Mortality

In Older Women With Breast Cancer QoL May Predict 10-Year Mortality

A model that incorporates HRQOL was found to outperform a model that only employs traditional prognostic variables.

Factoring in Breast Density Improves Long-Term Risk Models for Breast Cancer

Factoring in Breast Density Improves Long-Term Risk Models for Breast Cancer

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A study using a cohort of women from Kaiser Permanente Washington evaluated the accuracy of risk assessment models for breast cancer that included classic risk factors with and without breast density as an additional factor during more than 10 years of follow-up.

Heart-Specific Mortality Not Higher Among Breast Cancer Survivors

Heart-Specific Mortality Not Higher Among Breast Cancer Survivors

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A retrospective cohort study of data from the SEER database assessed the potential risk of cardiac-related mortality in patients with breast cancer, treated with chemotherapy or radiotherapy, vs the general population.

Palpable Cancers Detected at Smaller Size in Breasts With Implants

Palpable Cancers Detected at Smaller Size in Breasts With Implants

Researchers reviewed 48 cases of patients with prior breast augmentation undergoing breast cancer treatment to determine detection rate and treatment choices.

Benefit of Lymph Node Biopsies May Be Limited in Microinvasive Breast Cancer

Benefit of Lymph Node Biopsies May Be Limited in Microinvasive Breast Cancer

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Researchers sought to determine the benefit of managing microinvasive breast cancer similarly to invasive tumors in a retrospective study.

Does Better Breast Imaging Lead to Improved Outcomes or Increased Overdiagnosis?

Does Better Breast Imaging Lead to Improved Outcomes or Increased Overdiagnosis?

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Advances in breast imaging such as DBT offer better, clearer images of breast tissue that can identify even low-grade DCIS tumors. But will more sensitive imaging lead to improved outcomes or increased overtreatment?

Spousal, Partner Perception of Coping Affects Adjustments in Breast Cancer

Spousal, Partner Perception of Coping Affects Adjustments in Breast Cancer

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Male spouse or partner perspectives on a female patient's ability to cope was found to have a positive effect on her ability to cope and adjust to her disease. Unfortunately, this effect remains rarely researched and poorly understood among patients with breast cancer in same sex relationships.

Taxane Acute Pain Syndrome in Cancer Therapy: Occurrence, Impact on Quality of Life

Taxane Acute Pain Syndrome in Cancer Therapy: Occurrence, Impact on Quality of Life

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Results of a prospective study of patients with breast or prostate cancer demonstrate the impact of taxane-based chemotherapy on quality of life.

Choosing Wisely After Publication of Level I Evidence in Breast Cancer Radiotherapy

Choosing Wisely After Publication of Level I Evidence in Breast Cancer Radiotherapy

[Breast Cancer: Targets and Therapy] In this retrospective analysis of medical records and estimated costs of treatment, investigators demonstrated that rapid change based on level I evidence is feasible.

Increases in CVD Risk Factors Associated With Worse Survival in Breast Cancer

Increases in CVD Risk Factors Associated With Worse Survival in Breast Cancer

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Researchers assessed outcomes of elderly patients with breast cancer to identify the correlation between cardiovascular disease risk factors and overall survival in survivors older than 66.

Women With Schizophrenia May Be at Greater Risk for Breast Cancer

Women With Schizophrenia May Be at Greater Risk for Breast Cancer

Pooled analysis indicated that schizophrenia was associated with a significantly increased risk of breast cancer incidence in women, but researchers had some reservations with the results.

Direct-to-Consumer Genetic Test for Select <i>BRCA</i> Mutations Gets FDA Nod

Direct-to-Consumer Genetic Test for Select BRCA Mutations Gets FDA Nod

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The US FDA has approved a consumer test that may indicate increased breast and ovarian cancer risk in some individuals.

Intervention Improves Breast Cancer Survivors' Memory Contentment

Intervention Improves Breast Cancer Survivors' Memory Contentment

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Results of a prospective study demonstrated the effectiveness of a 1-hour psychoeducational intervention designed to help survivors of breast cancer manage their chemotherapy-related cognitive dysfunction and improve their memory contentment.

Breast Cancer Screening Recommendations Not Completely Reflective of Race, Age

Breast Cancer Screening Recommendations Not Completely Reflective of Race, Age

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An analysis of SEER data sought to examine the appropriateness of age- and race-specific breast cancer screening recommendations for white vs nonwhite women in the United States.

Cost vs Benefits: The Controversy Over Proton Beam Radiotherapy

Cost vs Benefits: The Controversy Over Proton Beam Radiotherapy

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At $225 million per system, the precision of proton beam radiotherapy is not necessarily overshadowing its high costs. Yet ongoing studies seek to determine how this technology fits into current treatment regimens for prostate, breast, and other cancers.

Patient Expectations at Odds With Actual Outcomes for Radiotherapy in Breast Cancer

Patient Expectations at Odds With Actual Outcomes for Radiotherapy in Breast Cancer

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Researchers present the results of a survey of patients with breast cancer who underwent radiation therapy to assess the difference between their pretreatment expectations and their actual experience.

Calcitriol May Improve Hormone-Therapy Induced Osteoporosis in Breast Cancer Survivors

Calcitriol May Improve Hormone-Therapy Induced Osteoporosis in Breast Cancer Survivors

In this study, researchers determined the efficacy of calcitriol, weight-bearing exercise, both, or daily multivitamins on bone formation and resorption in breast cancer survivors actively maintained on hormone therapy.

Profile of Buparlisib and its Potential in the Treatment of Breast Cancer: Evidence to Date

Profile of Buparlisib and its Potential in the Treatment of Breast Cancer: Evidence to Date

[Breast Cancer: Targets and Therapy] A review of studies investigating the efficacy of buparlisib monotherapy and in combination with various other anticancer agents in the treatment of breast cancer and other solid tumors.

Factors Affecting Employment Participation in Early-stage Breast Cancer

Factors Affecting Employment Participation in Early-stage Breast Cancer

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Researchers conducted a multivariate analysis to determine the factors that contribute to employment participation among women with early-stage breast cancer.

Induced Pluripotent Stem Cell Vaccine May Help Prevent Tumor Growth

Induced Pluripotent Stem Cell Vaccine May Help Prevent Tumor Growth

iPSC vaccine prevented tumor growth in syngeneic murine breast CA, mesothelioma, melanoma models

Chemotherapy-Related Fatigue Linked to Levothyroxine Use in Breast Cancer

Chemotherapy-Related Fatigue Linked to Levothyroxine Use in Breast Cancer

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In a secondary analysis of the BEATE and INVEST study, researchers followed a link between levothyroxine use, exercise, and fatigue in women with breast cancer undergoing chemotherapy.

Self-Predictions for Well-Being Influence Satisfaction After Mastectomy, Breast Reconstruction

Self-Predictions for Well-Being Influence Satisfaction After Mastectomy, Breast Reconstruction

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Observational study assessed the influence of patients' self-predictions for well-being after undergoing mastectomy for breast cancer with or without immediate breast reconstruction.

Anticancer Properties of Omega-3 Fatty Acids: Plant-Based vs Marine-Based

Anticancer Properties of Omega-3 Fatty Acids: Plant-Based vs Marine-Based

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Researchers compared the association between diets high in plant-based omega-3 polyunsaturated fatty acids (PUFAs) vs those high in marine-based PUFAs and the risk for breast cancer.

Breast Cancer Therapies Associated With Increased Risk for Cardiovascular Disease

Breast Cancer Therapies Associated With Increased Risk for Cardiovascular Disease

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Advances in breast cancer treatment are improving outcomes for patients with the disease; however, treatments are increasing these patients' risk for cardiovascular diseases.

Cardiotoxicity Risk Greater in Blacks With Breast Cancer Receiving HER2 Therapies

Cardiotoxicity Risk Greater in Blacks With Breast Cancer Receiving HER2 Therapies

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Retrospective study examines the association between risk of cardiotoxicity and race in women with breast cancer receiving chemotherapy and at least 1 year of HER2-targeted therapy.

Breast Cancer Recurrence and CV Risks Down With Exercise in Survivors

Breast Cancer Recurrence and CV Risks Down With Exercise in Survivors

Exercise intervention was associated with improved z-score and serum biomarkers in obese survivors of breast cancer.

Acupuncture Benefits Aromatase Inhibitor-Related Joint Pain

Acupuncture Benefits Aromatase Inhibitor-Related Joint Pain

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Acupuncture may represent an effective adjuvant therapy in the management of joint pain associated with aromatase inhibitor treatment in postmenopausal women with breast cancer.

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