Breast Cancer

Breast-Conserving Surgery Recommended For Younger Women With Breast Cancer

Breast-Conserving Surgery Recommended For Younger Women With Breast Cancer

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A study finds that report that overall outcomes and prognosis have significantly improved over time for women aged 40 years and younger with breast cancer who undergo breast conserving surgery, and the procedure should be recommended to these patients.

Adjuvant Partial Breast Radiotherapy Noninferior in Preventing Relapse in Local Breast Cancer

Adjuvant Partial Breast Radiotherapy Noninferior in Preventing Relapse in Local Breast Cancer

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Partial-breast and reduced-dose radiotherapy was found to be noninferior in preventing local relapse compared with whole-breast radiation therapy in patients with early stage breast cancer with a lower-than-average risk of relapse.

Emerging Treatments for HER2-positive Early-stage Breast Cancer: Focus on Neratinib

Emerging Treatments for HER2-positive Early-stage Breast Cancer: Focus on Neratinib

[OncoTargets and Therapy] This research reviews available data on the role of the HER2 pathway in breast cancer and on the different targeted agents for the treatment of patients with early-stage HER2-positive disease, with a particular focus on neratinib.

A Systematic Literature Review Exploring the Prevalence of Post-traumatic Stress Disorder and the Role Played by Stress and Traumatic Stress in Breast Cancer Diagnosis and Trajectory

A Systematic Literature Review Exploring the Prevalence of Post-traumatic Stress Disorder and the Role Played by Stress and Traumatic Stress in Breast Cancer Diagnosis and Trajectory

[Breast Cancer: Targets and Therapy] This research examines literature regarding the prevalence of PTSD in breast cancer patients and reviews mechanisms by which stress impacts cancer risk.

Physical Activity Improves Cognitive Function for Breast Cancer Survivors

Physical Activity Improves Cognitive Function for Breast Cancer Survivors

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Moderate-to-vigorous physical activity was found to improve working memory and executive function in survivors of breast cancer.

Deodorant, Antiperspirant Use During Radiation Therapy for Breast Cancer Not Detrimental

Deodorant, Antiperspirant Use During Radiation Therapy for Breast Cancer Not Detrimental

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Use of antiperspirant or deodorant does not adversely affect potential for dermal toxicity or surface concentrations of aluminum in the axilla in women undergoing radiation therapy for breast cancer.

Bilateral Mastectomy Without Proper Genetic Counseling

Bilateral Mastectomy Without Proper Genetic Counseling

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Many women with breast cancer with genetic variants of uncertain significance (VUS) undergo testing and bilateral mastectomy without receiving genetic counseling.

Disease-Free Survival After Breast Cancer Comparable With Exemestane, Sequential Tamoxifen/Exemestane

Disease-Free Survival After Breast Cancer Comparable With Exemestane, Sequential Tamoxifen/Exemestane

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A 10-year follow-up study finds disease-free survival (DFS) comparable with exemestane and sequential tamoxifen/exemestane in patients with HR-positive breast cancer.

Vitamin D3 Supplementation Has No Impact on Breast Density Percentage, Breast Cancer Risk

Vitamin D3 Supplementation Has No Impact on Breast Density Percentage, Breast Cancer Risk

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Supplementation with vitamin D3 in premenopausal women does not have a significant effect on breast density percentage, nor does it reduce breast cancer risk.

A Review of CDK4/6 Toxicities and Interactions Management in Breast Cancer

A Review of CDK4/6 Toxicities and Interactions Management in Breast Cancer

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CDK4/6 inhibitors, which block the activity of regulatory enzymes, are tolerated fairly well in patients with cancer; however, oncology nurses should be aware of some strategies that minimize their adverse effects.

Relationship Between Breast Cancer and Posttraumatic Stress Disorder Inconclusive

Relationship Between Breast Cancer and Posttraumatic Stress Disorder Inconclusive

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Although a strong correlation between breast cancer diagnosis and stress has been noted — particularly in the form of posttraumatic stress disorder (PTSD) — there is no demonstrable evidence to suggest a direct causal relationship between them.

Counseling Regarding Genetic Testing in Breast Cancer Lacking, Yet Many Still Undergo BLM

Counseling Regarding Genetic Testing in Breast Cancer Lacking, Yet Many Still Undergo BLM

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Many women with breast cancer with genetic VUS undergo testing and bilateral mastectomy (BLM) without ever receiving genetic counseling.

Fat Grafting May Lead to Better Outcomes in Postmastectomy Breast Reconstruction

Fat Grafting May Lead to Better Outcomes in Postmastectomy Breast Reconstruction

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Fat grafting provides benefits to women with breast cancer considering their options for postmastectomy breast reconstruction, even though this study shows that patient-reported outcomes are similar among women who did and did not undergo the procedure.

Adherence to NCCN Guidelines for Chest CT in Early Stage Breast Cancer Lacking

Adherence to NCCN Guidelines for Chest CT in Early Stage Breast Cancer Lacking

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A report on adherence to NCCN Guidelines found that, contrary to guideline recommendations, many asymptomatic patients with stage I/II breast cancer undergo chest CT for pulmonary nodules.

Novel 3D Marker Reduces Radiation, Improves Cosmesis in Breast Conserving Surgery

Novel 3D Marker Reduces Radiation, Improves Cosmesis in Breast Conserving Surgery

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Two recent studies examined the benefits of using a 3D bioabsorbable marker to indicate the tumor bed in women with breast cancer who underwent breast conserving surgery (BCS).

Cancer Risks for BRCA1/2 Mutation Carriers Determined by Age, Family History, Mutation Location

Cancer Risks for BRCA1/2 Mutation Carriers Determined by Age, Family History, Mutation Location

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Risk assessment study for carriers of the BRCA1/2 mutation identified the factors that influence their risk of developing breast cancer, ovarian cancer, or contralateral breast cancer.

Breast Cancer Overdiagnosis Also a Result of Screening Mammography Programs

Breast Cancer Overdiagnosis Also a Result of Screening Mammography Programs

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Screening mammography programs increased early detection of tumors, improving outcomes for those women; however, these programs also increased detection of tumors that would never pose a clinical problem.

Aspirin Use May Lower Breast Cancer Risk in Women with Diabetes

Aspirin Use May Lower Breast Cancer Risk in Women with Diabetes

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Regular aspirin use is associated with a lower risk of breast cancer among women with diabetes, a recent study from Taiwan has shown.

Ethnic Differences, Cultural Barriers Negatively Impact Mammography Follow-up Among Asian Ethnic Groups

Ethnic Differences, Cultural Barriers Negatively Impact Mammography Follow-up Among Asian Ethnic Groups

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Follow-up after abnormal results on mammography is more likely to be delayed among Asian American women compared with white women, and varies between different Asian ethnicities.

Changes in Pulmonary Function Tests in Breast Carcinoma Patients Treated With Locoregional Post-mastectomy Radiotherapy: Results of a Pilot Study

Changes in Pulmonary Function Tests in Breast Carcinoma Patients Treated With Locoregional Post-mastectomy Radiotherapy: Results of a Pilot Study

[Breast Cancer: Targets and Therapy] The goal of this research was to evaluate the acute changes in PFTs in breast carcinoma patients who received adjuvant chemotherapy and were treated with PMRT including SC regions.

QOL, Adverse Effects Better With Capecitabine After Adjuvant Epirubicin for Breast Cancer

QOL, Adverse Effects Better With Capecitabine After Adjuvant Epirubicin for Breast Cancer

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Women with breast cancer who received capecitabine after adjuvant epirubicin had better quality of life (QOL) compared with those who received CMF after adjuvant therapy.

Taxane-based Chemotherapy May Diminish Balance, Gait in Breast Cancer Survivors

Taxane-based Chemotherapy May Diminish Balance, Gait in Breast Cancer Survivors

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Breast cancer survivors who received taxane-based chemotherapy for their disease are at increased risk for falls due to CIPN and treatment-associated effects on balance and gait.

Weight-Loss Program Aids African-American Breast Cancer Survivors

Weight-Loss Program Aids African-American Breast Cancer Survivors

Community-based, interventionist-guided weight loss program was efficacious for early-stage survivors.

Adding Pertuzumab to Adjuvant Therapy Is Beneficial for Some Women with Early Breast Cancer

Adding Pertuzumab to Adjuvant Therapy Is Beneficial for Some Women with Early Breast Cancer

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Adding a second HER2-blocker to standard care therapy after surgery for HER2-positive breast cancer may be modestly beneficial for some women.

Breast Cancer Diagnosis and Nurse Navigation Survey

Breast Cancer Diagnosis and Nurse Navigation Survey

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A patient survey was designed to examine patient views of their initial breast cancer diagnosis process and care management.

Nurse-Led Psychological Intervention Beneficial in Breast Cancer

Nurse-Led Psychological Intervention Beneficial in Breast Cancer

Participants with high risk of depression reported lower mood disturbance, anxiety, depression following intervention.

Ovarian Function Recovery May Increase Risk of Breast Cancer Recurrence

Ovarian Function Recovery May Increase Risk of Breast Cancer Recurrence

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Ovarian function recovery (OFR) in women with chemotherapy-induced ovarian function failure decreases residual 5-year disease-free and overall survival.

Novel Approach Increases Breast, Ovarian Cancer Genetic Screening

Novel Approach Increases Breast, Ovarian Cancer Genetic Screening

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A questionnaire added to intake forms at a breast cancer imaging center identified women with BRCA mutations who might otherwise have been missed.

Interactive Tool Improves Breast Cancer Treatment Decision-Making

Interactive Tool Improves Breast Cancer Treatment Decision-Making

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A tool called iCanDecide prepares patients for making decision about treatment better than static online information, study finds.

Treatment for Breast Cancer in Men Differs From Treatment for Women

Treatment for Breast Cancer in Men Differs From Treatment for Women

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Male breast cancer patients are less likely than their female counterparts to receive adjuvant hormone therapy and postlumpectomy radiation.

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