For patients with schizophrenia and breast cancer, adjuvant radiation therapy may not be preferable

For patients with schizophrenia and breast cancer, adjuvant radiation therapy may not be preferable

For patients with schizophrenia and breast cancer, initial radical surgery without adjuvant radiation therapy may be preferred.

Diabetes and its treatment impact prognosis in patients with breast cancer

Diabetes and its treatment impact prognosis in patients with breast cancer

Pre-existing diabetes increases risk of total mortality among women with breast cancer.

Link found between duration of smoking habit and risk for breast cancer

Link found between duration of smoking habit and risk for breast cancer

A recent study has found a modest association between smoking and breast cancer risk in women.

Patients under 21 with breast or colorectal cancer more likely to have aggressive disease

Patients under 21 with breast or colorectal cancer more likely to have aggressive disease

When breast and colorectal cancers occur in children, the diseases are aggressive.

Generic aromatase inhibitors improve adherence by 50%

Generic aromatase inhibitors improve adherence by 50%

Generic aromatase inhibitors improved treatment adherence by 50% in hormone receptor-positive breast cancer.

New guidelines published for the use of complementary therapies in patients with breast cancer

New guidelines published for the use of complementary therapies in patients with breast cancer

Relaxation and yoga are the best complementary therapies for the treatment of breast cancer.

Yoga practice and frequency improved self-reported cognitive problems among breast cancer survivors

Yoga practice and frequency improved self-reported cognitive problems among breast cancer survivors

Recent trial investigated the impact of a yoga intervention on fatigue and inflammation among breast cancer survivors.

Chest radiation to treat Wilms tumor may increase risk for developing breast cancer

Chest radiation to treat Wilms tumor may increase risk for developing breast cancer

Children who underwent chest radiation for the treatment of Wilms tumor may have an increased risk for developing breast cancer.

Benefit seen for adding trastuzumab to breast cancer chemotherapy

Benefit seen for adding trastuzumab to breast cancer chemotherapy

Herceptin in addition to chemotherapy boosts survival, reduces risk of cancer recurrence

70-Gene signature not likely to be cost-effective for breast cancer

70-Gene signature not likely to be cost-effective for breast cancer

Findings in comparative economic analysis of patients with node-negative breast cancer showed the 70-gene signature is unlikely to be cost-effective for guiding adjuvant chemotherapy decision making.

Breast cancer is more accurately diagnosed after PET/CT imaging in younger patients

A change in diagnosis resulted from PET/CT imaging of patients who were younger than 40 years with an initial diagnosis of stage I-III breast cancer, according to a retrospective analysis.

Medicare subsidy program helps breast cancer patients afford treatment

Medicare subsidy program helps breast cancer patients afford treatment

'Extra Help' program allows more women of varying racial and ethnic backgrounds to continue their hormone therapy.

Pertuzumab adds survival benefit for HER2-positive breast cancer

Pertuzumab adds survival benefit for HER2-positive breast cancer

Patients with HER2-positive breast cancer that has metastasized demonstrate longer survival outcomes if treated with a combination of pertuzumab, trastuzumab, and chemotherapy.

Healthy lifestyle may increase survival for breast cancer survivors

Healthy lifestyle may increase survival for breast cancer survivors

A healthy lifestyle may improve survival of patients with breast cancer.

For women treated for breast cancer, health intervention program improves quality of life

For women treated for breast cancer, health intervention program improves quality of life

Women treated for breast cancer improved their quality of life after participating in post-treatment intervention.

HER2 inhibition shows promise in HER2-positive non-small cell lung cancer

Human epidermal growth factor receptor 2 (HER2) mutations may offer an important treatment target in a subset of patients with non-small cell lung cancer.

Experts plea for continuing research and education in advanced breast cancer

Breast cancer experts world-wide have urged for continued high quality research on advanced breast cancer.

Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization (ALTTO) study confirms use of trastuzumab for HER2-positive breast cancer

The use of trastuzumab (Herceptin) as the standard-of-care treatment for HER2-positive breast cancer has been supported by the Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization (ALTTO) study.

Tool successfully distinguishes between breast cancer and normal tissues

Researchers have successfully tested a new tool that will help surgeons better distinguish cancerous breast tissue from normal tissue, which should lower the mount of repeat procedures needed.

The 'Angelina Effect' for breast cancer was immediate, and long-lasting

Referrals for genetic counseling and testing for breast cancer risk more than doubled across the United Kingdom after Angelina Jolie's May 2013 announcement she tested positive for BRCA1 gene mutation and underwent a double mastectomy.

For patients with breast cancer, oral bisphosphonates may reduce risk for developing bone metastases

For patients with breast cancer, oral bisphosphonates may reduce risk for developing bone metastases

Oral bisphosphonates to treat osteoporosis may also slow skeletal metastases caused by breast cancer.

Breast Positioning during Mammography: Mistakes to be Avoided

Breast Positioning during Mammography: Mistakes to be Avoided

[Breast Cancer (Auckl)] Breast positioning is the key factor affecting a mammogram. Done properly, correct positioning maximizes the amount of breast tissue being imaged, eliminates most of the artifacts, and increases sensitivity of the mammogram.

'Electronic skin' could improve early breast cancer detection

Scientists are now developing an "electronic skin" that will aid in the detection of breast masses.

Nighttime dim light exposure may increase breast cancer resistance to doxorubicin

Nighttime dim light exposure may increase breast cancer resistance to doxorubicin

Exposure to dim light at night may make breast tumors resistant to chemotherapy

Disparities persist in early stage breast cancer treatment

Despite its acceptance as standard of care neary 25 years ago, barriers still exist that preclude patients from receiving breast conserving therapy (BCT), according to research presented at the ASCO 2014 Breast Cancer Symposium.

Adding drugs to standard chemotherapy improves response in triple-negative breast cancer

Adding drugs to standard chemotherapy improves response in triple-negative breast cancer

Adding carboplatin and/or bevacizumab to the standard treatment regimen significantly improved pathologic complete response rates in patients with triple-negative breast cancer, according to a new phase 2 study.

ESMO: Herceptin may be best option for HER2 breast cancer treatment

ESMO: Herceptin may be best option for HER2+ breast cancer treatment

Drug should remain standard of care for HER2-positive tumors, according to new research.

No association found between wearing a bra and breast cancer

No association found between wearing a bra and breast cancer

A recent study found no link between bra wearing and increased breast cancer risk among postmenopausal women.

Once-weekly breast radiation regimen improves on current treatment

An experimental regimen of once-weekly breast irradiation after lumpectomy provides more convenience to patients at less expense, and results in better completion rates of prescribed radiation treatment.

Reconstituting nab-paclitaxel

Reconstituting nab-paclitaxel

Is there a good reason to mix nab-paclitaxel (Abraxane) with warm (not cool) normal saline when reconstituting?

Novel immunotherapy vaccine decreases recurrence of HER2-positive breast cancer

Novel immunotherapy vaccine decreases recurrence of HER2-positive breast cancer

A new immunotherapy vaccine candidate for breast cancer shows promise, having reduced recurrence rate by more than fifty percent.

One skirt size increase every 10 years elevates breast cancer risk

One skirt size increase every 10 years elevates breast cancer risk

Women whose skirt size increases one size every 10 years have a 33% increased risk for developing breast cancer.

Clinical trial results of nintedanib for HER2-negative breast cancer are promising

The experimental drug nintedanib, in combination with standard paclitaxel chemotherapy, caused a total remission of tumors in half of patients with early stage HER2-negative breast cancer.

For patients with breast cancer in one breast, many are satisfied with opting for double mastectomy

For patients with breast cancer in one breast, many are satisfied with opting for double mastectomy

Most women who chose to undergo double mastectomies despite having cancer in only one breast are content with their choice.

Screening elderly women for breast cancer not efficacious

Screening elderly women for breast cancer not efficacious

Mammograms for those aged 69 to 75 could result in over-treatment, researchers caution.

Better classifications improve treatment planning for breast cancer

Scientists have developed a tool to distinguish each breast cancer subtype, research that could improve treatments and targeting of treatments for the disease.

Tumor cells prep lymphatic cells to encourage breast cancer cells to spread

Breast cancer cells can lay the groundwork for their own metastasis throughout the body by coaxing cells within lymphatic vessels to send out tumor-welcoming signals.

Molecular subtyping can improve breast cancer treatment

Molecular subtyping can improve breast cancer treatment

The BluePrint genomic test provides more accurate information about the molecular subtype of a specific breast cancer, compared with the use of conventional IHC-FISH pathology tests, according to a new study.

'Overdiagnosis' in breast cancer screening is still not understood

One-third of women who are given information about the potential for over-diagnosis through the National Health Services (NHS) breast screening program may not completely understand the risks involved.

Screening women over age 70 for breast cancer may lead to overdiagnosis

Screening women over age 70 for breast cancer may lead to overdiagnosis

Screening women for breast cancer up to age 75 may lead to overdiagnosis and overtreatment.

Breast cancer risk may be lower for women with diverse gut bacteria

Breast cancer risk may be lower for women with diverse gut bacteria

Postmenopausal women with a diverse gut microbiome have higher levels of estrogen metabolites.

Double mastectomy rates are up, but survival is not improved

The percentage of women that underwent a double mastectomy increased substantially between 1998 and 2011, even though the procedure was not associated with a lower risk of death than breast-conserving surgery plus radiation.

Women with severe, chronic health issues undergo breast cancer screening less often

Women with severe disabilities and multiple chronic conditions are screened for breast cancer less often than women with no disabilities or no chronic conditions.

In HER2 positive breast cancer, vaccine reduces recurrence

In HER2 positive breast cancer, vaccine reduces recurrence

GP2, a novel immunotherapy, has demonstrated a reduction in recurrence in patients with breast cancer.

Integrated approach to pinpoint genetic drivers of cancer uncovers viable targets for breast cancer therapy

Researchers have developed a new integrated approach to identify the genetic drivers of cancer, uncovering eight genes necessary for cell proliferation in breast cancer.

Soy may be detrimental for women with breast cancer

Soy may be detrimental for women with breast cancer

Study raises questions about the effect of soy's estrogen-like properties.

ASCO: Family doctors can improve mammogram return rates

ASCO: Family doctors can improve mammogram return rates

Women overdue for mammogram respond better to postcard plus reminder letter from family physician.

Biomarker highly promising for predicting breast cancer outcomes

A protein named p66ShcA shows promise as a biomarker to identify breast cancers with poor prognoses, according to new research.

Guidelines issued for HER2-negative breast cancer

Guidelines issued for HER2-negative breast cancer

Evidence-based recommendations have been developed for chemotherapy and targeted therapy for women with HER2-negative advanced breast cancer.

ASCO: Angelina Jolie announcement responsible for BRCA1/2 testing boost

ASCO: Angelina Jolie announcement responsible for BRCA1/2 testing boost

Celebrity story helped double rates of genetic testing in following six months at one cancer center.

ASCO: Risks greater for double mastectomy

ASCO: Risks greater for double mastectomy

Women with breast cancer who have a double mastectomy are at higher risk of certain complications than those who have a single mastectomy, though the overall complication rate associated with breast cancer surgery is small.

Breast cancer not linked to bras

Breast cancer not linked to bras

Wearing bras does not increase a woman's risk for developing breast cancer.

Surgery to Reduce the Risk of Breast Cancer (Fact Sheet)

Surgery to Reduce the Risk of Breast Cancer (Fact Sheet)

This fact sheet examines the potential pros and cons of surgery as a means to reduce breast cancer risk.

Perspectives on breast reconstruction following mastectomy vary among patients

Following a mastectomy, less than 42% of women underwent breast reconstruction, and the factors associated with foregoing reconstruction included being black, being less educated, and being older.

ASCO: Factors that influence contralateral preventive mastectomy

ASCO: Factors that influence contralateral preventive mastectomy

Survey of women with breast cancer explores factors in the decision to remove a healthy breast as a measure to prevent breast cancer.

Bilateral mastectomy rates rise from 1998 to 2011

Bilateral mastectomy rates rise from 1998 to 2011

Bilateral mastectomy-linked mortality rates are up for women diagnosed with stage 0 to III breast cancer.

For patients with breast cancer, double mastectomy does not reduce mortality

For patients with breast cancer, double mastectomy does not reduce mortality

Despite an increase in double mastectomy for early-stage breast cancer, the procedure does not reduce the risk of mortality.

Biomarker for aggressive, basal-like breast cancer identified

A biomarker strongly linked to basal-like breast cancer has been identified.

Black Women's Health Study (BWHS) shows exercise improves breast cancer risk for African American women

This recently published study found strong evidence linking physical exercise to a lower rate of breast cancer in African American women, a group in which previous evidence has been lacking.

Bone drugs may not protect osteoporotic women from breast cancer

Osteoporosis drugs known as bisphosphonates may not protect women from breast cancer as had been thought, according to a new study.

Endogenous hormones improve breast cancer risk prediction

Endogenous hormones improve breast cancer risk prediction

Inclusion of endogenous hormones in prediction models improves prediction of invasive breast cancer risk in postmenopausal women, according to a study.

Postmenopausal breast cancer risk drops off after starting regular physical activity

Postmenopausal women who in the past 4 years had undertaken regular physical activity equivalent to at least 4 hours of walking per week had a lower risk for invasive breast cancer compared with women who exercised less

Mutations in the PALB2 gene increases risk of breast cancer by age 70 years

The PALB2 gene is potentially one of the most important genes associated with breast cancer after the BRCA1/2 genes.

NSAIDs may lower breast cancer recurrence in overweight and obese women

Recurrence of hormone-related breast cancer was reduced by 50% in overweight and obese women who regularly used aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs), according to newly published data.

Dasatinib may be effective against several cancers

Dasatinib may be effective against several cancers

Dasatinib shows promise for treating skin, breast and several other cancers.

MRI more effective at detecting recurrent breast cancer

MRI more effective at detecting recurrent breast cancer

MRI detects 18.1 additional cancers after negative findings with mammography and ultrasonography per 1,000 women.

Bisphosphonate use may not prevent breast cancer

Bisphosphonate use may not prevent breast cancer

Data from two randomized controlled trials suggest that bisphosphonate use does not protect against postmenopausal breast cancer, according to research.

NSAIDs linked to decreased breast cancer recurrence among obese women

NSAIDs linked to decreased breast cancer recurrence among obese women

In overweight women, aspirin or other drugs might make certain breast cancers more treatable.

Expressive writing improves health outcomes for breast cancer survivors

Writing down fears, emotions, and the benefits of a cancer diagnosis may improve health outcomes for Asian American survivors of breast cancer, according to a new study. The research investigated methods of reducing the psychological burden among minority patients, particularly among breast cancer survivors.

Cancer categories recast in largest-ever genomic study

New research suggests that cancer would be more accurately diagnosed in 1 of every 10 patients if their tumors were defined by cellular and molecular criteria rather than by the tissues in which they originated, and that this information, in turn, could lead to more appropriate treatments.

Mammography benefits women older than 75 years

Mammography-detected breast cancer is associated with a shift to earlier stage diagnosis in older women, subsequently reducing the rate of more advanced, difficult-to-treat cases. Researchers said the findings lend support to regular mammography screening in women age 75 years and older.

New mutations may increase breast cancer risk

New mutations may increase breast cancer risk

Mutations in PALB2 and germline mutations in the multiple endocrine neoplasia type 1 (MEN1) tumor-suppressor gene causing MEN1 correlate with increased breast cancer risk, according to two studies.

Acupuncture improves quality of life for breast cancer patients taking aromatase inhibitors (AIs)

Electroacupuncture (EA) produces significant improvements in fatigue, anxiety, and depression in as little as 8 weeks for patients with early stage breast cancer experiencing joint pain related to the use of aromatase inhibitors to treat breast cancer.

Exercise reduces the risk of breast cancer in older women

Exercise reduces the risk of breast cancer in older women

Older women intent on keeping breast cancer at bay may want to start and maintain a regular exercise regimen.

Women 75+ may still benefit from routine mammograms

Women 75+ may still benefit from routine mammograms

Breast cancer survival has been found to be better in women whose cancer was detected by mammography.

Acupuncture reduces comorbid symptoms of cancer pain

Acupuncture reduces comorbid symptoms of cancer pain

Electroacupuncture may reduce comorbid symptoms of pain in women with breast cancer who have aromatase inhibitor-related arthralgia, according to research.

Ginger as a treatment for breast cancer

Ginger as a treatment for breast cancer

Research published in the Journal of Biomedicine and Biotechnology suggests that ginger may be a promising breast cancer treatment.

Recent use of some birth control pills may increase breast cancer risk

Recent use of some birth control pills may increase breast cancer risk

Women who recently used birth control pills containing high-dose estrogen and a few other formulations had an increased risk for breast cancer, whereas women using some other formulations did not, according to recent data.

Gel formulation of tamoxifen significantly reduces side effects related to the oral formulation

A gel form of tamoxifen applied to the breasts of women with noninvasive breast cancer reduced the growth of cancer cells to the same degree as the drug taken in oral form but with fewer side effects.

Mammograms may be beneficial for women over 75

Mammograms may be beneficial for women over 75

According to a study published in Radiology, women over 75, a population not typically included in mammography screening effectiveness studies, may benefit from mammograms.

Possible target for immunotherapy in early stage breast cancer identified

A new molecular analysis tool accurately detected the level of an important target for immunotherapy in early stage breast cancers.

Breast cancer survivors benefit from writing about their experiences

Breast cancer survivors benefit from writing about their experiences

A new study demonstrated that writing about emotionally difficult events, such as a cancer diagnosis, might improve outcomes for some breast cancer survivors.

Sleeping in darkness boosts breast cancer drug effectiveness

Sleeping in darkness boosts breast cancer drug effectiveness

Keeping a light on at night can suppress the body's production of a hormone called melatonin, possibly reducing the effectiveness of the breast-cancer drug tamoxifen, a study suggests.

Exposure to dim light at night may lead to tamoxifen resistance in breast cancer

For rats bearing human breast tumors, exposure to dim light at night made the tumors resistant to the breast cancer drug tamoxifen, according to recently published data.

Navigators can help guide patients with breast cancer through care

Navigators can help guide patients with breast cancer through care

A team of researchers from Boston University School of Medicine sought to determine the impact of patient navigators on the care of low-income and African-American women with breast cancer.

Electroacupuncture improves quality of life for breast cancer patients using AIs

Electroacupuncture improves quality of life for breast cancer patients using AIs

Use of electroacupuncture produces significant improvements in fatigue, anxiety, and depression in as little as 8 weeks for patients with early stage breast cancer patients experiencing joint pain related to the use of AIs to treat breast cancer.

Genes linked to breast cancer in East Asian women identified

A new study has identified three genetic changes in East Asian women linked to an increased risk of breast cancer.

Rethinking Breast Cancer Screening: Ultra FAST Breast MRI [EDITORIALS]

Rethinking Breast Cancer Screening: Ultra FAST Breast MRI [EDITORIALS]

Breast cancer screening is once again controversial. In this editorial, the author discusses new research demonstrating the effectiveness of an MRI imaging technique called first postcontrast subtracted T1-weighted image (FAST).

Standard of care for delivering bisphophonates

Standard of care for delivering bisphophonates

What is the preferred delivery protocol for breast cancer adjuvant bisphosphonates?

Genetics is the dominant risk factor for familial breast, prostate, and colorectal cancers

Genetics is the dominant risk factor for familial breast, prostate, and colorectal cancers

A study of people who were adopted identified genetics as the dominant risk factor in familial breast, prostate, and colorectal cancers.

No change seen in breast cancer detection despite increased Medicare costs for screening

Breast cancer screening costs for Medicare patients skyrocketed between 2001 and 2009, but the increase did not lead to earlier detection of new breast cancer cases, according to a study.

Hormones after breast cancer: natural steroid hormones may be safe, effective

Hormones after breast cancer: natural steroid hormones may be safe, effective

A new study suggests a safe and effective role for natural steroid hormones in treating postmenopausal breast cancer, with fewer detrimental side effects and improved health profile than with standard antihormone therapies.

New blood test predicts risk of nonhereditary breast cancer

New blood test predicts risk of nonhereditary breast cancer

A simple blood test is currently in development that could help predict the likelihood of a woman developing breast cancer, even in the absence of a high-risk BRCA1 gene mutation, according to new research.

Gene marker may help predict breast cancer response to tamoxifen

Gene marker may help predict breast cancer response to tamoxifen

Researchers have identified genes that may help predict whether a patient with estrogen receptor (ER)-positive breast cancer is likely to benefit from tamoxifen therapy.

Genetic profile and potential drug susceptibility of breast cancer cells revealed by CTCs

Circulating tumor cells captured with a microchip-based device can be cultured to establish cell lines for genetic analysis and drug testing.

Parabens in Cosmetics: What Is the Connection to Cancer?

Parabens in Cosmetics: What Is the Connection to Cancer?

Current studies indicate that the levels of parabens used in cosmetics are safe (typical levels are 0.1% to 0.3%); however, many believe a relationship to cancer exists, particularly breast cancer. The furor came about after a 2004 study reported finding parabens in the breast tissue of 20 women.

Update of staging criteria for breast cancer diagnosis recommended

New findings paint a relatively optimistic picture of women's chances of surviving a subset of breast cancers that have spread to the chest wall or skin, but not beyond.

Scientists bring personalized medicine for breast cancer one step closer

Scientists bring personalized medicine for breast cancer one step closer

The era of personalized medicine for breast cancer may be just around the corner, thanks to recent advances by USC Stem Cell researcher Min Yu and scientists at Massachusetts General Hospital and Harvard Medical School.

Cultured circulating tumor cells reveal genetic profile of breast cancer cells

Cultured circulating tumor cells reveal genetic profile of breast cancer cells

Researchers have created a microchip device that can capture circulating tumor cells, in order to track ongoing genetic mutation within a tumor.

Protein pushes breast cancer cells to metastasize

Using an innovative tool that captures heretofore hidden ways that cells are regulated, scientists have identified a protein that makes breast cancer cells more likely to metastasize.

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