Researchers compared tiny variations in the genetic make-up of more than 120,000 women of European ancestry, with and without breast cancer, and identified 15 new genetic variations linked to a higher risk of the disease.
Patients with larger malignant tumors of the breast who undergo chemotherapy before breast cancer surgery are more likely to opt for a breast-preserving procedure, according to a new study.
A regional anesthetic technique in combination with standard care could potentially spare a third of women undergoing a mastectomy chronic post-operative pain, according to study data.
Breast screening via ultrasound is unaffected by breast density, is not associated with ionizing radiation, and does not require IV contrast material, but acceptance of this modality has lagged.
Breast cancer in women with diabetes is more likely to be advanced stage at diagnosis.
Black and Hispanic women with breast cancer are less likely to select a surgeon or determine hospital based on reputation.
An association of high rates of inappropriate imaging for prostate cancer and breast cancer found in a study of Medicare beneficiaries suggests that regional culture could contribute to inappropriate imaging.
Disparities exist regarding the level of awareness and knowledge of breast density among US women, according to a study.
Household net worth can be linked to adherence to hormonal therapy among breast cancer patients and partially explains racial disparities in quality of care.
A newly developed surface for silicone breast implants could greatly increase the chance that they are properly assimilated by the body without rejection.
They found that women who received a reminder were 20% more likely to attend their breast cancer screening appointment.
Scientists believe that targeting blood vessel cells known as pericytes may offer a potential new therapeutic approach for breast and other cancers.
A family history of prostate cancer among first-degree relatives may increase a woman's risk of developing breast cancer, according to a new study.
A new program developed by UCLA researchers may ease post-treatment "chemo brain" in patients with breast cancer.
Magnetic resonance spectroscopy (MRS) shows precancerous breast changes in women with BRCA gene mutation
MRS that incorporates monitoring of biochemical changes in tissue could improve the management of women at risk of breast cancer, according to a new study.
Regional infrastructure could contribute to inappropriate imaging in patients at risk for prostate and breast cancer.
Researchers continue to examine the effects of massage therapy and how it may help to reduce fatigue in patients with breast cancer.
Laws mandating notification of dense breasts may pose a risk of unnecessary procedures and false positives for women at low- and moderate-risk of breast cancer.
This case study examines a case of sex-related headaches in a breast cancer survivor after treatment for ductal carcinoma in situ (DCIS).
Use of the gonadotropin-releasing hormone agonist, goserelin, protects against ovarian failure, according to a study.
A new patient-centered mobile app entitled Share the Journey: Mind, Body and Wellness after Breast Cancer has launched.
Women with a family history of prostate cancer in first-degree relatives may have a higher risk of developing breast cancer.
Lipid and metabolite deregulation were seen in breast tissue of women carrying BRCA1/2 mutations.
Knowledge of the risk of over-detection and over-diagnosis associated with mammography screening can lower intentions to undergo breast screening, according to a new Lancet study.
Breast cancer during pregnancy presents additional psychosocial challenges as patients cope with a devastating diagnosis during a time of hope and promise for the future.
Female breast cancer survivors may be at an increased risk for developing thyroid cancer.
Many physicians who tested their breast-examination skills on a new type of pressure-sensing breast model failed to detect masses deep in the breast because they were administering adequate pressure, a study has found.
Women undergoing radiotherapy for breast cancer can use deodorant without increasing risk of underarm skin reactions, pain, itching, or burning.
A worldwide study of the DNA of 100,000 women has discovered two new genetic variants associated with an increased risk of breast cancer.
Researchers have discovered that ERBB4 (also known as HER4) is a driver protein in ERBB2-positive tumors that have developed resistance to first- or second-line treatments.
Cells that contain lower levels of protein profilin 1 in breast tumors have an increased capacity to metastasize and invade other tissues, according to research.
Risks and benefits of routine mammography continue to be debated, but educating women about the possibility of overdiagnosis from mammography screening may make some of them less likely to get the test.
Newly discovered segments of DNA shared by African American family members who have breast cancer indicate there may still be undiscovered breast cancer genes that may be unique to African Americans.
More than a third of women who should receive radiation subsequent to mastectomy are actually undergoing the recommended postmastectomy radiation therapy (PMRT), according to a new study.
Household net worth is a major factor in adherence to hormonal therapy among patients with breast cancer.
Specific methylation patterns revealed in the primary biopsy breast cancer cells of breast cancer DNA methylome can indicate a better or worse prognosis.
Not all women with lymph node-positive breast cancer treated with chemotherapy before surgery need to have all underarm nodes removed, new research indicates.
Half of primary care physicians are still unfamiliar with the California law mandating that clinicians notify women with dense breast tissue, and many do not feel comfortable answering breast density-related questions.
A new risk prediction model will allow for greater accuracy in predicting risk for breast cancer in African American women.
Women who are better informed about the risk of over-detection are less likely to have a breast cancer screening.
Radiotherapy can be avoided by older women with breast cancer without a compromise to their safety, according to a recent study.
Smoking is associated with an increased risk of breast cancer, prostate cancer, and routine infections.
In treatment for metastatic breast cancer, eribulin is effective as a first-, second-, or third-line chemotherapy regimen.
Researchers examined the benefits and risks associated with taking drug tamoxifen for breast cancer prevention.
Average long-term weight gain among breast cancer survivors is small, but certain subgroups experience greater gain associated with adverse health.
Many patients with locally advanced breast cancer do not undergo recommended postmastectomy radiotherapy
Only 65% of patients with advanced breast cancer are receiving the postsurgical radiation therapy.
Ibrance (palbociclib) has been approved by the U.S. Food and Drug Administration (FDA) for postmenopausal women with ER, HER2-negative metastatic breast cancer.
A new breast cancer risk model that combines histologic features of biopsied breast tissue from women with benign breast disease and individual patient demographic information more accurately classified breast cancer risk.
New imaging technique significantly improves detection of invasive breast cancers in dense breast tissue
A new breast imaging technique greatly increases the ability to detect invasive breast cancer in women with dense breast tissue, a number in which half of women of screening age are counted.
Current research has identified a signaling pathway responsible for the generation of slowly proliferating cancer cells that are hard to eradicate via current treatments.
Postmenopausal women who were metabolically unhealthy are at increased risk for breast cancer compared with their metabolically healthy counterparts, according to a recent study.
A recent study provides a comprehensive analysis of the molecular alterations at work in phyllodes tumors, a rare type of breast tumor.
The FDA granted accelerated approved for palbociclib (Ibrance) for the treatment of advanced breast cancer.
Many women with breast cancer lack important knowledge about their illness, with minority patients less likely than white patients to know and report accurate information about their tumors' characteristics.
Researchers continue to be fascinated and challenged by the multifactorial nature of breast cancer.
How much more toxicity and myelosuppression has been associated with gemcitabine (Gemzar) when it is infused over periods longer than 30 minutes?
New research seeks to better understand why breast cancer spreads to the brain, with the goal of developing a way to reduce the risk of this phenomenon.
Biopsy frequency went up after diagnostic, but not screening, mammographies.
Many women with breast cancer lack basic knowledge about their disease, and the problem is more pronounced among minority women.
Effectiveness of nanoparticle drugs was hindered by tumor microenvironment in triple-negative breast cancer
Nanoparticle drugs were considered to be a potential silver bullet against cancer, but they have not produced the anticipated improvement in overall survival rates.
A study of approximately 375,000 U.S. women with invasive breast cancer showed differences in likelihood of diagnosis occurring at an early stage, and survival after stage I diagnosis, based on by race and ethnicity.
Histologic features of biopsied breast tissue from benign findings along with demographic data to more accurately determine risk.
An intervention aimed at an under-represented group of Latina breast cancer survivors helped encourage better eating habits and nutrition.
Providing nutrition education to patients with breast cancer could be beneficial for patients and may help to prevent recurrence of their cancer, according to new research.
Mind body techniques added to aerobic exercise improve rehabilitation outcomes in breast cancer survivors
Researchers sought to determine the impact of aerobic exercise training and yoga on survivorship measures in breast cancer survivors.
Eribulin is active and well tolerated as first-, second-, or third-line therapy in patients with metastatic breast cancer.
Study of postmenopausal women suggests hormone levels matter more than excess weight, with regard to predicting breast cancer risk.
Women with stage 1 HER2-positive breast tumors who received a combination of lower-intensity chemotherapy and a targeted drug following surgery were unlikely to suffer cancer recurrence within 3 years of treatment.
The researchers have mapped the steps used by cells of melanoma, breast cancer, and the blood cancer myelofibrosis to become resistant to drugs, allowing for better success in blocking these pathways and further enabling therapies.
Findings in a quasi-experimental study of Taiwanese women with early-stage breast cancer showed the potential for exercise to reduce fatigue in women undergoing radiotherapy.
Younger women with early stage breast cancer who had completed cancer treatment to a 6-week Mindful Awareness Practices (MAPS).
Febrile neutropenia-related hospitalizations still account for morbidity, and mortality among patients with breast cancer.
The odds of being early breast cancer development and survival chances vary greatly depending on race and ethnicity, according to a new study.
A new study has better established the future risk of developing breast cancer for those with atypical hyperplasia of the breast.
Race and ethnicity may play a role in the timing of breast cancer diagnosis and the prognosis of the woman's disease.
According to results of a new, retrospective study, the risk of developing leukemia after radiation therapy or chemotherapy for early stage breast cancer is double that previously reported.
Research indicates that women who undergone mastectomy have greater satisfaction when breast reconstruction is performed using the patient's own tissues, rather than implants.
Trastuzumab significantly improves the long-term survival of HER-2 positive breast cancer patients, according to a large national study.
For women undergoing breast reconstruction, autologous reconstruction leads to higher satisfaction than alloplastic reconstruction, but secondary correction is often required.
Researchers believe they may have found a molecule-based approach to halting the destructive quality of the 3q26.2 amplicon, a frequent chromosomal aberrations seen in many cancers, including ovarian and breast cancers.
Women over 70 years with early stage breast cancer are very likely to receive radiation therapy, despite evidence of that it might not be the best form of treatment.
New intra-operative technology aids lumpectomy procedures by detecting microscopic amounts of cancer cells on tumor tissue.
Considerations for women with atypical hyperplasia include screening and chemoprevention, and more patient education is often needed.
Discussions on basic disease information between patients with metastatic breast cancer, caregivers, and oncologists.
Supplemental breast cancer screening with ultrasound may increase costs more than overall health in women with dense breasts
Supplemental ultrasound screening for all US women with dense breasts would substantially increase health care costs with little improvement in overall health.
The most commonly used medications for osteoporosis worldwide, bisphosphonates, may also prevent certain kinds of lung, breast, and colon cancers, according to two recent studies.
A study of breast cancers detected with screening mammography found that strong family history and dense breast tissue were commonly absent in women ages 40 to 49 years at diagnosis of breast cancer.
Researchers conducted a study to determine whether there is a differential effect of race on outcomes for women with breast cancer.
Although the use of a radiation treatment that is shorter in duration and less costly has increased among women with early stage breast cancer who underwent breast conserving surgery, most patients who meet guidelines to receive this treatment do not.
Three studies presented at the 2014 San Antonio Breast Cancer Symposium (SABCS): Cancer risk test detected 105% more mutations in cancer-causing genes than conventional BRCA testing alone; researchers at leading cancer research institutions validate use of companion diagnostic test to detect a DNA scar in tumor that is indicative of a dysfunctional DNA repair pathway; UK researchers evaluated the use of companion diagnostic assays to identify which patients would respond to carboplatin or docetaxel.
Researchers have found that subcutaneous trastuzumab has a similar safety profile and similar event-free survival rate with intravenous trastuzumab.
Two subgroups of breast tumors have been identified, based on epigenetic alterations.
Among early-stage breast cancer patients who undergo chemotherapy and/or radiation treatment, the risk for developing treatment-related leukemia, though low, is still double what experts had previously thought.
Researchers have developed a new device that may help make mammography more comfortable for women.
Digital breast tomosynthesis has the potential to significantly increase the cancer detection rate of mammography screening in women that have dense breasts.
A new digital program using a Web site and social media aims to meet the unique support needs of women younger than 40 years with breast cancer.
The addition of bevacizumab to standard presurgery chemotherapy showed greater benefit in those whose cancers were classified as basal-like by gene expression assay, compared with those whose cancers were nonbasal-like.
Fulvestrant did more to improve survival than anastrozole for patients with advanced, hormone receptor-positive breast cancer, according to data.
A breast cancer vaccine is safe in patients with metastatic breast cancer, as indicated by the results of an early clinical trial.
- Angelina Jolie has ovaries, fallopian tubes removed over cancer concerns
- Drug sequence with gemcitabine
- Counseling cancer patients on effective nutritional practices
- Radiation plus immunotherapy revs up immune system to better attack melanoma
- Online education tool helps bridge gaps in therapeutic decision-making for NSCLC
- Fifteen new breast cancer genetic risk 'hot-spots' revealed
- High fitness level may decrease risk of colorectal, lung cancers
- Discontinuing statin therapy safe, beneficial for patients with terminal illness
- Affect of chemotherapy on saliva test results
- Childhood leukemia study reveals disease subtypes and new treatment options
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