Trastuzumab improves survival for HER2-positive breast cancer

Trastuzumab improves survival for HER2-positive breast cancer

Trastuzumab improved overall survival in early-stage human epidermal growth factor receptor 2 (HER2)-positive breast cancer.

Vaccine targeting breast cancers produced robust immune response

A DNA vaccine targeting the breast cancer-associated antigen mammaglobin-A was proven safe and found to effectively elicit immune responses in women with metastatic breast cancer, according to a new study.

Patients with BRCA 1/2 mutations not at increased risk for anthracycline-induced cardiotoxicity

Patients with BRCA 1/2 mutations not at increased risk for anthracycline-induced cardiotoxicity

Breast cancer patients with BRCA 1/2 gene mutations do not have an increased risk of anthracycline-induced cardiac toxicity.

No association between migraine and breast cancer risk

No association between migraine and breast cancer risk

There is no associated between migraines and risk of breast cancer.

Dietary interventions can improve clinical outcomes for some women with breast cancer

Dietary interventions can improve clinical outcomes for some women with breast cancer

Reducing dietary intake of fat reduces death rates in some women with early stage breast cancer.

National trends in mastectomy for early stage breast cancer examined

An increasing number of of women eligible for breast conservation surgery (BCS) are opting instead for mastectomy, breast reconstruction, and bilateral mastectomy.

Many breast cancer patients overtreated with radiation therapy

Many breast cancer patients overtreated with radiation therapy

Two-thirds of breast-conserving surgical patients undergo six to seven weeks of radiation, but three weeks of higher-dose radiation could be more beneficial.

Inherited mutations typical in triple-negative breast cancer

Inherited mutations typical in triple-negative breast cancer

Deleterious mutations were identified in 14.6 percent of patients in a cohort unselected for family history.

Researchers suggest new follow-up model for breast cancer patients

The surveillance and follow-up of breast cancer survivors has the potential to improve, from the perspective of both patients and the health system.

Study confirms recommendations for genetic screening in patients with triple-negative breast cancer

Study confirms recommendations for genetic screening in patients with triple-negative breast cancer

A recent study recommends that patients with triple-negative breast cancer should undergo genetic testing for mutations in known breast cancer predisposition genes, including BRCA1 and BRCA2.

Smoking cessation prior to first child decreases risk of breast cancer

Smoking cessation prior to first child decreases risk of breast cancer

Many breast cancer cases in mothers can be averted if women do not smoke cigarettes prior to the birth of their first child.

Breast cancer vaccine shows promise in early testing

Breast cancer vaccine shows promise in early testing

An experimental breast cancer vaccine boosts immune response and appears to slow spread in those with advanced disease.

Counseling over the phone provides access to genetic testing for women in rural areas

Telephone counseling after genetic testing was found just as effective as in-person counseling in many respects, according to new study.

Bisphosphonates may reduce risk of certain breast, colon, and lung cancers

Bisphosphonates may reduce risk of certain breast, colon, and lung cancers

Bisposphonates may also prevent certain types of breast, colon, and lung cancers.

Combining genetic information with risk factors could improve breast cancer prediction

Combining genetic data with information on other risk factors could significantly improve the ability to identify women at highest risk of developing breast cancer, according to a new study.

Current breast cancer treatments measure better than past therapies

Current breast cancer treatments measure better than past therapies

Significant improvements in breast cancer outcomes found despite similar patterns of relapse, research shows.

Can consensus guidelines defining adequate margins decrease unnecessary breast cancer surgeries?

Nearly one quarter of all women who underwent initial breast conservation surgery (BCS) for breast cancer had a subsequent surgical intervention.

Exercise therapy benefits breast cancer survivors

Exercise offers several benefits for breast cancer survivors, including reduced symptoms of lymphedema, according to a new study.

BRCA-related tumors respond to olaparib

Olaparib, an experimental oral cancer drug, has shown an overall tumor response rate of 26% in advanced cancers associated with BRCA1 and BRCA2 mutations, according to recent research.

Prosocial Internet support group not proving beneficial for breast cancer survivors

Prosocial Internet support group not proving beneficial for breast cancer survivors

Participants in prosocial versus standard group have higher level of depression, anxiety after intervention.

Mastectomy numbers on the rise in women eligible for lumpectomy

Mastectomy numbers on the rise in women eligible for lumpectomy

Better breast reconstruction outcomes may be one reason behind the trend of increasing mastectomy rates for early-stage breast cancer patients eligible for lumpectomy.

Helper therapy principle may not be helpful for breast cancer

Helper therapy principle may not be helpful for breast cancer

Distressed survivors or breast cancer may not benefit from helping others, as the helper therapy principle would suggest.

Inadequately management of hot flushes leave women vulnerable

More than 70% of women who have had breast cancer experience menopausal problems, hot flushes in particular, and some cancer survivors consider giving up their post cancer medication to mitigate these conditions.

Complementary, alternative medicine may have higher risk for excessive bleeding during breast cancer surgery

Complementary, alternative medicine may have higher risk for excessive bleeding during breast cancer surgery

Breast cancer patients using herbal supplements had increased risk for adverse bleeding-related outcomes.

More patients opt for mastectomy despite limited, early-stage breast cancer

More patients opt for mastectomy despite limited, early-stage breast cancer

More women with breast cancer are opting for mastectomy rather than undergoing breast conservation surgery.

Calcium channel blockers not found to increase risk of breast cancer

Calcium channel blockers not found to increase risk of breast cancer

Women who take calcium channel blockers to treat their hypertension are not at increased risk for developing breast cancer.

Proton therapy less costly than some alternative radiotherapy techniques

Partial breast irradiation (APBI) with proton therapy, as opposed to whole breast irradiation (WBI), may prove more affordable and have a more beneficial length of treatment for patients with early stage breast cancer.

Preventative therapies for healthy women at high risk of breast cancer

Preventative therapies for healthy women at high risk of breast cancer

SERMs and aromatase inhibitors have been proven to be excellent agents in the preventive setting for ER-positive breast cancer, but newer agents must be found specifically for ER-negative breast cancers, which mostly occur in premenopausal women.

Telephone Support Intervention Beneficial for BRCA Carriers

Telephone Support Intervention Beneficial for BRCA Carriers

Reduction in distress, unmet information needs with telephone-based, peer-support program

Cellular evidence for mind-body connection in breast cancer survivors

Researchers have demonstrated that employing mindfulness meditation or being a member of a support group has a positive physical impact at the cellular level in breast cancer survivors.

New software determines aggressiveness of breast cancer

New software determines aggressiveness of breast cancer

Newly developed software enables genetic mutation analysis of breast cancer tumors, allowing for greater accuracy.

Adding tomosynthesis to mammography is cost effective for dense breasts

The addition of tomosynthesis to biennial digital mammography screening for women with dense breasts should improve breast cancer detection at a reasonable cost.

Treatment options for HER2-positive breast cancer

Treatment options for HER2-positive breast cancer

What are the treatment options for recurrent metastatic HER2-positive breast cancer after trastuzumab therapy?

The Society for Integrative Oncology (SIO) and co-researchers issue a report card on complementary therapies for breast cancer

The Society for Integrative Oncology (SIO) and co-researchers issue a report card on complementary therapies for breast cancer

A majority of breast cancer patients in the U.S. use complementary therapies after a breast cancer diagnosis, but there has been little science-based guidance about their safety and effectiveness.

Mexican women with family history more likely to have triple-negative breast cancer vs. other types

Mexican women with family history more likely to have triple-negative breast cancer vs. other types

Patients of Mexican descent with breast cancer and family history of breast or ovarian cancer were nearly two times as likely to have triple negative breast cancer.

Breast cancer tumor response to neoadjuvant chemotherapy (NAC) measured

Diffuse optical spectroscopic tomographic imaging (DOST) may be useful in predicting which patients will best respond to chemotherapy used to reduce breast cancer tumors before surgery, according to a new study.

Latina patients with breast cancer more given more information more likely to enter clinical trials

Latina patients with breast cancer more given more information more likely to enter clinical trials

Latina patients with breast cancer had much more awareness of clinical trials versus women who received the typical information.

People with lactose intolerance may have decreased risk of breast, lung, and ovarian cancers

People with lactose intolerance may have decreased risk of breast, lung, and ovarian cancers

People who are lactose intolerant have a decreased risk for developing breast, lung, and ovarian cancers.

Trastuzumab shows benefit years after treatment for HER2+ breast cancer

The addition of trastuzumab to chemotherapy significantly improved the overall and disease-free survival of women with early stage HER2-positive breast cancer.

For breast cancer survivors, tai chi decreases inflammation

For breast cancer survivors, tai chi decreases inflammation

Tai chi may reduce the risk of breast cancer recurrence by decreasing inflammation in patients who have had breast cancer.

Patients with breast cancer at long-term increased risk of first depression

Patients with breast cancer at long-term increased risk of first depression

Women with breast cancer are at an increased long-term risk for developing first depression.

Survival comparable after radiation therapy for tumors in left or right breast

Location of a breast cancer tumor, on the left or right side, does not impact overall survival in patients treated with breast-conserving surgery and adjuvant external beam radiation therapy.

Why early stage breast cancer survivors opt for mastectomy

Cancer stage may play a role in the decision to undergo mastectomy rather than lumpectomy for women with early stage breast cancer, according to recent research.

Exercise therapy, acupuncture improve strength and decrease pain in breast cancer survivors

Exercise therapy, acupuncture improve strength and decrease pain in breast cancer survivors

Researchers identified the benefits of exercise therapy and electro-acupuncture in breast cancer survivors.

Link between obesity and breast cancer confirmed for blacks and Hispanics

Link between obesity and breast cancer confirmed for blacks and Hispanics

For black women and Hispanic women, obesity increases postmenopausal risk of estrogen receptor (ER)-negative and progesterone receptor-positive breast cancer.

For breast cancer survivors, meditation may cause beneficial cellular changes

For breast cancer survivors, meditation may cause beneficial cellular changes

Mindfulness mediation has effects on the cellular level of the body of breast cancer survivors.

Cancer prehabilitation: One step toward improved outcomes

Cancer prehabilitation: One step toward improved outcomes

As cancer care evolves toward anticipatory rather than reactionary care, oncology nurses should consider developing important new skills.

Hot flashes may not be managed adequately in patients treated for breast cancer

Hot flashes may not be managed adequately in patients treated for breast cancer

Hot flashes experienced by women who have been treated for breast cancer are not being sufficiently addressed by clinicians.

Subsidies help breast cancer patients adhere to hormone therapy

A federal prescription-subsidy program for low-income Medicare recipients has increased adherence to hormone therapy to prevent breast cancer recurrence after surgery, according to recent data.

Generic aromatase inhibitors may help breast cancer patients stick to therapy

Generic aromatase inhibitors may help breast cancer patients stick to therapy

Cost is a key factor for women to maintain their hormone treatment regimen, researchers report.

Digital mammography plus tomosynthesis cost-effective for dense breasts

Digital mammography plus tomosynthesis cost-effective for dense breasts

The combined breast screening cost-effective over a range of incremental improvements in test performance.

Radiologist performance improved on own recalled mammogram screens

Radiologist performance improved on own recalled mammogram screens

The researchers found that the sensitivity, false-positive rate, and cancer detection rate of screening mammography increased with increasing numbers of radiologist work-ups for their own recalled mammograms.

Fluorescent tattoos may improve self-esteem in patients receiving radiotherapy for breast cancer

Fluorescent tattoos may improve self-esteem in patients receiving radiotherapy for breast cancer

Invisible tattoos preferable option to mark where a patient with breast cancer should receive radiotherapy during sessions.

Vaginal lubricant options for women with hormone-receptor positive (HR+) cancer

Vaginal lubricant options for women with hormone-receptor positive (HR+) cancer

What vaginal lubricants are available for for women with hormone-receptor positive (HR+) cancer?

For patients with schizophrenia and breast cancer, adjuvant radiation therapy may not be preferable

For patients with schizophrenia and breast cancer, adjuvant radiation therapy may not be preferable

For patients with schizophrenia and breast cancer, initial radical surgery without adjuvant radiation therapy may be preferred.

Diabetes and its treatment impact prognosis in patients with breast cancer

Diabetes and its treatment impact prognosis in patients with breast cancer

Pre-existing diabetes increases risk of total mortality among women with breast cancer.

Link found between duration of smoking habit and risk for breast cancer

Link found between duration of smoking habit and risk for breast cancer

A recent study has found a modest association between smoking and breast cancer risk in women.

Patients under 21 with breast or colorectal cancer more likely to have aggressive disease

Patients under 21 with breast or colorectal cancer more likely to have aggressive disease

When breast and colorectal cancers occur in children, the diseases are aggressive.

Generic aromatase inhibitors improve adherence by 50%

Generic aromatase inhibitors improve adherence by 50%

Generic aromatase inhibitors improved treatment adherence by 50% in hormone receptor-positive breast cancer.

New guidelines published for the use of complementary therapies in patients with breast cancer

New guidelines published for the use of complementary therapies in patients with breast cancer

Relaxation and yoga are the best complementary therapies for the treatment of breast cancer.

Yoga practice and frequency improved self-reported cognitive problems among breast cancer survivors

Yoga practice and frequency improved self-reported cognitive problems among breast cancer survivors

Recent trial investigated the impact of a yoga intervention on fatigue and inflammation among breast cancer survivors.

Chest radiation to treat Wilms tumor may increase risk for developing breast cancer

Chest radiation to treat Wilms tumor may increase risk for developing breast cancer

Children who underwent chest radiation for the treatment of Wilms tumor may have an increased risk for developing breast cancer.

Benefit seen for adding trastuzumab to breast cancer chemotherapy

Benefit seen for adding trastuzumab to breast cancer chemotherapy

Herceptin in addition to chemotherapy boosts survival, reduces risk of cancer recurrence

70-Gene signature not likely to be cost-effective for breast cancer

70-Gene signature not likely to be cost-effective for breast cancer

Findings in comparative economic analysis of patients with node-negative breast cancer showed the 70-gene signature is unlikely to be cost-effective for guiding adjuvant chemotherapy decision making.

Breast cancer is more accurately diagnosed after PET/CT imaging in younger patients

A change in diagnosis resulted from PET/CT imaging of patients who were younger than 40 years with an initial diagnosis of stage I-III breast cancer, according to a retrospective analysis.

Medicare subsidy program helps breast cancer patients afford treatment

Medicare subsidy program helps breast cancer patients afford treatment

'Extra Help' program allows more women of varying racial and ethnic backgrounds to continue their hormone therapy.

Pertuzumab adds survival benefit for HER2-positive breast cancer

Pertuzumab adds survival benefit for HER2-positive breast cancer

Patients with HER2-positive breast cancer that has metastasized demonstrate longer survival outcomes if treated with a combination of pertuzumab, trastuzumab, and chemotherapy.

Healthy lifestyle may increase survival for breast cancer survivors

Healthy lifestyle may increase survival for breast cancer survivors

A healthy lifestyle may improve survival of patients with breast cancer.

For women treated for breast cancer, health intervention program improves quality of life

For women treated for breast cancer, health intervention program improves quality of life

Women treated for breast cancer improved their quality of life after participating in post-treatment intervention.

HER2 inhibition shows promise in HER2-positive non-small cell lung cancer

Human epidermal growth factor receptor 2 (HER2) mutations may offer an important treatment target in a subset of patients with non-small cell lung cancer.

Experts plea for continuing research and education in advanced breast cancer

Breast cancer experts world-wide have urged for continued high quality research on advanced breast cancer.

Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization (ALTTO) study confirms use of trastuzumab for HER2-positive breast cancer

The use of trastuzumab (Herceptin) as the standard-of-care treatment for HER2-positive breast cancer has been supported by the Adjuvant Lapatinib and/or Trastuzumab Treatment Optimization (ALTTO) study.

Tool successfully distinguishes between breast cancer and normal tissues

Researchers have successfully tested a new tool that will help surgeons better distinguish cancerous breast tissue from normal tissue, which should lower the mount of repeat procedures needed.

The 'Angelina Effect' for breast cancer was immediate, and long-lasting

Referrals for genetic counseling and testing for breast cancer risk more than doubled across the United Kingdom after Angelina Jolie's May 2013 announcement she tested positive for BRCA1 gene mutation and underwent a double mastectomy.

For patients with breast cancer, oral bisphosphonates may reduce risk for developing bone metastases

For patients with breast cancer, oral bisphosphonates may reduce risk for developing bone metastases

Oral bisphosphonates to treat osteoporosis may also slow skeletal metastases caused by breast cancer.

Breast Positioning during Mammography: Mistakes to be Avoided

Breast Positioning during Mammography: Mistakes to be Avoided

[Breast Cancer (Auckl)] Breast positioning is the key factor affecting a mammogram. Done properly, correct positioning maximizes the amount of breast tissue being imaged, eliminates most of the artifacts, and increases sensitivity of the mammogram.

'Electronic skin' could improve early breast cancer detection

Scientists are now developing an "electronic skin" that will aid in the detection of breast masses.

Nighttime dim light exposure may increase breast cancer resistance to doxorubicin

Nighttime dim light exposure may increase breast cancer resistance to doxorubicin

Exposure to dim light at night may make breast tumors resistant to chemotherapy

Disparities persist in early stage breast cancer treatment

Despite its acceptance as standard of care neary 25 years ago, barriers still exist that preclude patients from receiving breast conserving therapy (BCT), according to research presented at the ASCO 2014 Breast Cancer Symposium.

Adding drugs to standard chemotherapy improves response in triple-negative breast cancer

Adding drugs to standard chemotherapy improves response in triple-negative breast cancer

Adding carboplatin and/or bevacizumab to the standard treatment regimen significantly improved pathologic complete response rates in patients with triple-negative breast cancer, according to a new phase 2 study.

ESMO: Herceptin may be best option for HER2 breast cancer treatment

ESMO: Herceptin may be best option for HER2+ breast cancer treatment

Drug should remain standard of care for HER2-positive tumors, according to new research.

No association found between wearing a bra and breast cancer

No association found between wearing a bra and breast cancer

A recent study found no link between bra wearing and increased breast cancer risk among postmenopausal women.

Once-weekly breast radiation regimen improves on current treatment

An experimental regimen of once-weekly breast irradiation after lumpectomy provides more convenience to patients at less expense, and results in better completion rates of prescribed radiation treatment.

Reconstituting nab-paclitaxel

Reconstituting nab-paclitaxel

Is there a good reason to mix nab-paclitaxel (Abraxane) with warm (not cool) normal saline when reconstituting?

Novel immunotherapy vaccine decreases recurrence of HER2-positive breast cancer

Novel immunotherapy vaccine decreases recurrence of HER2-positive breast cancer

A new immunotherapy vaccine candidate for breast cancer shows promise, having reduced recurrence rate by more than fifty percent.

One skirt size increase every 10 years elevates breast cancer risk

One skirt size increase every 10 years elevates breast cancer risk

Women whose skirt size increases one size every 10 years have a 33% increased risk for developing breast cancer.

Clinical trial results of nintedanib for HER2-negative breast cancer are promising

The experimental drug nintedanib, in combination with standard paclitaxel chemotherapy, caused a total remission of tumors in half of patients with early stage HER2-negative breast cancer.

For patients with breast cancer in one breast, many are satisfied with opting for double mastectomy

For patients with breast cancer in one breast, many are satisfied with opting for double mastectomy

Most women who chose to undergo double mastectomies despite having cancer in only one breast are content with their choice.

Screening elderly women for breast cancer not efficacious

Screening elderly women for breast cancer not efficacious

Mammograms for those aged 69 to 75 could result in over-treatment, researchers caution.

Better classifications improve treatment planning for breast cancer

Scientists have developed a tool to distinguish each breast cancer subtype, research that could improve treatments and targeting of treatments for the disease.

Tumor cells prep lymphatic cells to encourage breast cancer cells to spread

Breast cancer cells can lay the groundwork for their own metastasis throughout the body by coaxing cells within lymphatic vessels to send out tumor-welcoming signals.

Molecular subtyping can improve breast cancer treatment

Molecular subtyping can improve breast cancer treatment

The BluePrint genomic test provides more accurate information about the molecular subtype of a specific breast cancer, compared with the use of conventional IHC-FISH pathology tests, according to a new study.

'Overdiagnosis' in breast cancer screening is still not understood

One-third of women who are given information about the potential for over-diagnosis through the National Health Services (NHS) breast screening program may not completely understand the risks involved.

Screening women over age 70 for breast cancer may lead to overdiagnosis

Screening women over age 70 for breast cancer may lead to overdiagnosis

Screening women for breast cancer up to age 75 may lead to overdiagnosis and overtreatment.

Breast cancer risk may be lower for women with diverse gut bacteria

Breast cancer risk may be lower for women with diverse gut bacteria

Postmenopausal women with a diverse gut microbiome have higher levels of estrogen metabolites.

Double mastectomy rates are up, but survival is not improved

The percentage of women that underwent a double mastectomy increased substantially between 1998 and 2011, even though the procedure was not associated with a lower risk of death than breast-conserving surgery plus radiation.

Women with severe, chronic health issues undergo breast cancer screening less often

Women with severe disabilities and multiple chronic conditions are screened for breast cancer less often than women with no disabilities or no chronic conditions.

In HER2 positive breast cancer, vaccine reduces recurrence

In HER2 positive breast cancer, vaccine reduces recurrence

GP2, a novel immunotherapy, has demonstrated a reduction in recurrence in patients with breast cancer.

Integrated approach to pinpoint genetic drivers of cancer uncovers viable targets for breast cancer therapy

Researchers have developed a new integrated approach to identify the genetic drivers of cancer, uncovering eight genes necessary for cell proliferation in breast cancer.

Soy may be detrimental for women with breast cancer

Soy may be detrimental for women with breast cancer

Study raises questions about the effect of soy's estrogen-like properties.

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