Detecting breast cancers when they are small still impacts survival despite the various effective therapies.
Previous studies addressed disparities by stage of disease and survival rates, but none of them characterized the patients by disease subtype.
An MR breast imaging technique that uses no ionizing radiation or contrast agent could reduce unnecessary biopsies by providing additional information about suspicious findings on conventional screening mammography, according to a new study.
Computer-aided detection (CAD) in screening mammography is not associated with improved diagnostic accuracy, according to an analysis of results from a large Breast Cancer Surveillance Consortium database of digital screening mammograms.
Researchers are working on a way to use artificial intelligence to predict a patient's response to two common chemotherapy drugs used to treat breast cancer: paclitaxel and gemcitabine.
Metastases cause the vast majority of cancer deaths, but their tiny seeds are so difficult to track. Now, scientists described studying individual metastatic cells from human breast cancer tumors implanted into mice as the cells escaped into the blood stream and began to form tumors elsewhere in the body.
Researchers discovered a new explanation for why women with ER+ breast cancer develop resistance to hormone treatment, and a potential new approach that may overcome the problem.
Although the software can be helpful, it does not appear to improve cancer detection rates.
Pegteograstim is as effective as pegfilgrastim in reducing chemotherapy-induced neutropenia in patients with breast cancer.
An eight-fold increase in preoperative breast MRI was seen over a 10-year period; MRI use was linked to more ancillary investigations.
Brief exposure to a targeted therapy can tell doctors which patients with HER2-negative breast cancer will respond and which should switch to another kind of treatment.
A new study may have uncovered the key to the early detection of patients at risk of developing metastasis to bone.
Breast cancer treatment options received considerable media attention when Angelina Jolie revealed she had undergone double mastectomy.
Patients with HER2-negative, axillary node-negative breast cancer and favorable 21-gene expression assay score had low rates of recurrence.
Researchers report an increase in breast cancer survivor's use of chronic medication after cancer treatment.
The number of high-risk women deemed eligible for primary prevention may be increased by incorporating benign breast disease (BBD) diagnoses into the Breast Cancer Surveillance Consortium (BCSC) risk model, according to a study.
Magnetic resonance imaging use is increasing in routine preoperative evaluation of women with breast cancer
Study to determine patterns in the utilization of preoperative breast magnetic resonance imaging (MRI) in a health care system with universal insurance.
The cumulative incidence of cardiac events (CE) at 6 years was slightly higher in patients with HER2-positive early breast cancer receiving trastuzumab.
Use of chemotherapy is inverse to disease risk in patients with breast cancer when genetic assay is used
Use of the 21-gene recurrence test score was associated with lower chemotherapy use in high-risk patients and greater use of chemotherapy in low-risk patients compared with not using the test score among a large group of Medicare beneficiaries, according to a recent investigation.
Differences in breast cancer recurrence and survival between African American women and white women are well established.
Chemotherapy-induced peripheral neuropathy (CIPN) was found to be common in a cohort of patients with early stage breast cancer.
Young black women with a breast cancer diagnosis at age 50 years or younger have a much higher BRCA mutation frequency than that previously reported among young white women with breast cancer.
Women who are obese have a higher risk and a worse prognosis for breast cancer, but the reasons why remain unclear.
A national risk model that gauges a woman's chance of developing breast cancer has been refined to give a more accurate assessment.
Women with ductal carcinoma in situ (DCIS) who undergo surgical resection without radiation have an increased risk of developing recurrence.
New software could speed up breast cancer diagnosis with 90% accuracy and without the need for a specialist.
Clinically meaningful weight loss over two years in overweight/obese survivors of breast cancer can be achieved via weight loss intervention.
Researchers estimate the 20-year breast cancer-specific death rate for women diagnosed with ductal carcinoma in situ to be 3.3%.
A high proportion of women who received false-positive results on screening mammography reported experiencing psychosocial consequences or trouble sleeping.
Chemotherapy prolongs life for older adults with most types of cancer, but for women older than 80 years with breast cancer, the chances of improved survival due to chemotherapy are significantly lower, according to a recent study.
The double mastectomy trend mirrors the one seen in women, researchers say.
Comparison of cardiac events associated with liposomal doxorubicin, epirubicin and doxorubicin in breast cancer: a Bayesian network meta-analysis - European Journal of Cancer
A recent study examined the cardiotoxicity of anthracyclines in patients with breast cancer.
The rates of contralateral prophylactic mastectomy (CPM) among men with breast nearly doubled between 2004 and 2011.
No new safety signals were identified for long-term denosumab therapy in patients with metastatic breast or prostate cancer and bone metastases.
In a study reviewing black women under 50 with invasive breast cancer, 12 percent had BRCA1 or BRCA2 mutations.
Circulating tumor DNA analysis spots stray cells months before scans detect breast cancer recurrence.
Researchers have pinpointed a novel genetic biomarker responsible for the progression of many breast and prostate cancers.
Researchers identify tumor microenvironment of metastasis (TMEM) that allows breast cancer to metastasize
Using high-resolution imaging, scientists have gained a greater understanding of how a doorway in the blood vessel wall allows cancer cells to metastasize.
Findings suggest obesity can trigger structural changes in extracellular matrix, rendering an individual more susceptible to breast cancer.
Researchers have developed a magnetic resonance imaging (MRI) contrast agent with the capability to pinpoint much smaller aggressive breast cancer tumors and micrometastases.
Previous studies have shown that following a 5-year course of tamoxifen after breast cancer treatment can reduce recurrence.
Electroacupuncture may be more effective and safer than gabapentin for managing hot flashes among breast cancer survivors.
Women diagnosed with ductal carcinoma in situ have a 20-year breast cancer-specific death rate of 3.3%.
Radiation to the lymph nodes as well as the standard treatment of whole-breast irradiation after breast-conserving surgery does not confer an overall survival benefit.
A better understanding of the association between barriers to care and clinical outcomes within patient navigation programs.
Breast cancer survivors with a body mass index (BMI) >25 who report the use of tamoxifen therapy may be at increased risk for arm lymphedema.
By surrounding molecules of paclitaxel with self-assembling spheres composed of amino acids, researchers doubled tumor exposure to the drug and reduced its effects on healthy tissue.
[Breast Cancer: Targets and Therapy] This research reviews the preclinical as well as clinical data on neratinib.
Including music therapy as a complementary approach with cancer surgery may help reduce preoperative anxiety.
A behavioral weight loss intervention can produce clinically meaningful weight loss in overweight/obese breast cancer survivors.
A revolutionary alternative to radical mastectomy has been developed that preserves the nipple, areola, and surrounding skin.
The effect of irradiation of regional nodes in patients with stage I, II, or III breast cancer on overall survival is very limited, according to a study.
Multigene testing for hereditary breast and/or ovarian cancer that tests is more likely to inform clinical decision-making than testing for BRCA1/2 alone.
Studies find aromatase inhibitors (AIs) and bisphosphonates improve survival in postmenopausal breast cancer patients
Two new studies suggest that two different classes of drugs, aromatase inhibitors (AIs) and bisphosphonates, can each improve survival prospects for postmenopausal women with early breast cancer.
Melatonin may be a potential therapeutic agent for improve sleep and quality of life in patients with metastatic breast cancer.
Chemotherapy does not improve survival for older women with breast cancer.
Cost of radiotherapy among Medicare patients varied most widely because of year of diagnosis, location of treatment, clinic type, and provider.
Postmenopausal women who exercised 300 minutes per week were better at reducing total fat, which could in turn lower their postmenopausal breast cancer risk.
Two studies show benefits for hypofractionated versus conventionally fractionated whole-breast irradiation.
With the availability of tomosynthesis mammography, should women at high risk for developing breast cancer still undergo annual MRI?
A diet that starves triple-negative breast cancer cells of an essential nutrient primes the cancer cells to be more easily killed by targeted treatment.
Research indicates that Angelina Jolie's announcement that she had tested positive for BRCA1 influenced some women's intentions to seek out similar genetic testing.
Shorter course of whole breast radiation therapy for early stage breast cancer results in less toxicity and improved quality of life.
Cultural differences in the Latino community result in unique stressors for these patients after a cancer diagnosis. This study identified some of those stressors.
Many breast cancer survivors in Appalachia neglect taking critical follow-up treatment, even though their insurance would cover the cost, a study has found.
Depression may increase the intensity of postoperative acute pain in women with breast cancer.
Single-stage implant procedures after mastectomy may be a good option for selected patients.
Receptors that mediate activity of the female sex hormones (estrogen and progesterone) interact with DNA to control the growth of a large majority of breast cancers, research indicates.
Irradiation of regional nodes in patients with stage I-III breast cancer has a minimal effect on overall survival.
ASCO 2015: 12-week dosing schedule of zoledronic acid is noninferior to a more-frequent schedule of every 4 weeks.
Magnetic resonance imaging (MRI) and near-infrared spectral tomography (NIRST) is feasible and more accurate than MRI alone
There is no clinically relevant evidence of an association between opioid prescriptions and breast cancer recurrence.
Breast cancer survivors who experience pain or discomfort during sexual intercourse may benefit from applying liquid lidocaine to the vulvar area.
More evidence that two classes of generic drugs (aromatase inhibitors and bisphosphonates) reduce the risk of death in early breast cancer.
Aromatase inhibitors significantly decrease the risk of death in postmenopausal women with estrogen receptor-positive breast cancer.
Some women who undergo additional radiation along with whole-breast irradiation may be at a reduced risk of breast cancer recurrence.
Contrary to popular expectations, the rates of advanced breast cancer have not generally declined in a number of countries where mammography screening is employed.
State regulations of health insurance and practitioners are significantly associated with time receive breast or colorectal cancer diagnoses.
Survivors of breast cancer who also have a family history of breast cancer were found to experience more weight gain in a four-year period than were cancer-free women.
Researchers have found that spending more leisure time sitting was associated with an increased risk for developing cancer in women.
Scientists have discovered a new protein which triggers the growth of blood vessels in breast cancer tumors that have spread to the brain.
A recent study examined both attitudes and cultural perspectives of Latinas undergoing chemotherapy for breast cancer.
Pretreatment cytokine levels are associated with reduced memory performance among newly diagnosed patients with post-menopausal breast cancer.
Tamoxifen with ovarian function suppression versus tamoxifen alone as an adjuvant treatment for premenopausal breast cancer: a meta-analysis of published randomized controlled trials
[OncoTargets and Therapy] This article examines possible survival benefits of ovarian function suppression (OFS) when combined with adjuvant tamoxifen treatment for breast cancer in premenopausal women.
No significant difference in breast cancer deaths seen in counties with higher screening and detection rates.
Investigators have discovered that the death-associated protein kinase 1 (DAPK1) is actually essential for growth in breast and other cancers with mutations in the TP53 gene.
The stress hormones often used to treat the side effects of chemotherapy could have the side effect of making effective cancer drugs fail sooner in some women with breast cancer, according to new research.
Selective use of biomarker testing for patients with breast cancer has the potential to save millions of dollars in health care spending without compromising care.
Clinical trial data suggests that postmenopausal women of above-average weight have an increased risk of breast cancer.
The percentage of patients with early stage breast cancer undergoing breast-conserving therapy (BCT) increased from 54.3% in 1998 to 60.1% in 2011, according to a recent report. Notably, nonclinical factors including socioeconomic demographics, insurance, and the distance patients must travel to treatment facilities persist as key barriers to the treatment.
Breast cancer patients with high levels of the protein activin-like receptor kinase (ALK1) in the blood vessels of their tumors were more likely to develop metastatic disease, according to a new study. This makes inhibition of the ALK1 pathway a possible new target for the treatment of metastatic breast cancer.
CHICAGO, IL—Functional subtyping with a multigene classifier resulted in 1 in 5 tumors being reclassified compared with conventional immunohistochemistry/fluorescent in situ hybridization (IHC/FISH) analysis. This study was presented at the 2015 American Society for Clinical Oncology (ASCO) Annual Meeting.
10% urea cream is superior to a newly introduced ointment containing various antioxidants at preventing hand-foot syndrome.
Randomized trial shows beneficial effect for yoga combined with meditation in breast cancer survivors.
The links between demographic, treatment, and socioeconomic factors and breast cancer survival were examined in a recent study.
Women diagnosed with breast cancer and treated with a one-week regimen of partial breast radiation after tumor removal saw no increase in cancer recurrence or difference in cosmetic outcomes.
The presence of extra body fat causes increased risk of diabetes and heart disease, and also increases the chances for breast cancer recurrence.
The discovery of an enzyme that facilitates the spread of breast cancer may enable clinicians to prevent secondary cancer.
Embryo cryopreservation after aromatase inhibitor treatment and ovarian stimulation preserves fertility for patients with breast cancer, according to a study published online.
Premenopausal women with breast cancer are at increased risk of dying if they smoke.
- Gay, Bisexual Men Report Higher Rates of Skin Cancer Than Heterosexual Men
- Clinical Trial Demonstrates Superior Results With Immunotherapy vs Chemotherapy for Lung Cancer
- Half-Match Donors May be the Perfect Match In Transplantation for Blood Cancers
- Initial Safety Report Finds Acceptable Safety With Ibrutinib for Asymptomatic, High-Risk CLL
- Older Patients with Hodgkin Lymphoma Benefit from Treatment with Brentuximab Vedotin
- Tumor Grade (Fact Sheet)
- Harms of Cigarette Smoking and Health Benefits of Quitting (Fact Sheet)
- Two-Drug Combination Shows Promise Against One Type of Pancreatic Cancer
- Clinical Trial Shows Vaccine Clears Some Precancerous Cervical Lesions
- Nutrition counseling recommended to reduce malnutrition in oncology patients
- Investigational Therapy Efficiently Depletes Immune System-Suppressing Treg Cells
- Handling closed system device-incompatible chemotherapy agents
- Detecting Cancer While It Is Still Small Impacts Survival
- Antioxidants May Be Harmful in Patients With Melanoma
- Gene Therapy Doubles Survival in Recurrent Glioblastoma
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