In a study reviewing black women under 50 with invasive breast cancer, 12 percent had BRCA1 or BRCA2 mutations.
Circulating tumor DNA analysis spots stray cells months before scans detect breast cancer recurrence.
Researchers have pinpointed a novel genetic biomarker responsible for the progression of many breast and prostate cancers.
Researchers identify tumor microenvironment of metastasis (TMEM) that allows breast cancer to metastasize
Using high-resolution imaging, scientists have gained a greater understanding of how a doorway in the blood vessel wall allows cancer cells to metastasize.
Findings suggest obesity can trigger structural changes in extracellular matrix, rendering an individual more susceptible to breast cancer.
Researchers have developed a magnetic resonance imaging (MRI) contrast agent with the capability to pinpoint much smaller aggressive breast cancer tumors and micrometastases.
Previous studies have shown that following a 5-year course of tamoxifen after breast cancer treatment can reduce recurrence.
Electroacupuncture may be more effective and safer than gabapentin for managing hot flashes among breast cancer survivors.
Women diagnosed with ductal carcinoma in situ have a 20-year breast cancer-specific death rate of 3.3%.
Radiation to the lymph nodes as well as the standard treatment of whole-breast irradiation after breast-conserving surgery does not confer an overall survival benefit.
A better understanding of the association between barriers to care and clinical outcomes within patient navigation programs.
Breast cancer survivors with a body mass index (BMI) >25 who report the use of tamoxifen therapy may be at increased risk for arm lymphedema.
By surrounding molecules of paclitaxel with self-assembling spheres composed of amino acids, researchers doubled tumor exposure to the drug and reduced its effects on healthy tissue.
[Breast Cancer: Targets and Therapy] This research reviews the preclinical as well as clinical data on neratinib.
Including music therapy as a complementary approach with cancer surgery may help reduce preoperative anxiety.
A behavioral weight loss intervention can produce clinically meaningful weight loss in overweight/obese breast cancer survivors.
A revolutionary alternative to radical mastectomy has been developed that preserves the nipple, areola, and surrounding skin.
The effect of irradiation of regional nodes in patients with stage I, II, or III breast cancer on overall survival is very limited, according to a study.
Multigene testing for hereditary breast and/or ovarian cancer that tests is more likely to inform clinical decision-making than testing for BRCA1/2 alone.
Studies find aromatase inhibitors (AIs) and bisphosphonates improve survival in postmenopausal breast cancer patients
Two new studies suggest that two different classes of drugs, aromatase inhibitors (AIs) and bisphosphonates, can each improve survival prospects for postmenopausal women with early breast cancer.
Melatonin may be a potential therapeutic agent for improve sleep and quality of life in patients with metastatic breast cancer.
Chemotherapy does not improve survival for older women with breast cancer.
Cost of radiotherapy among Medicare patients varied most widely because of year of diagnosis, location of treatment, clinic type, and provider.
Postmenopausal women who exercised 300 minutes per week were better at reducing total fat, which could in turn lower their postmenopausal breast cancer risk.
Two studies show benefits for hypofractionated versus conventionally fractionated whole-breast irradiation.
With the availability of tomosynthesis mammography, should women at high risk for developing breast cancer still undergo annual MRI?
A diet that starves triple-negative breast cancer cells of an essential nutrient primes the cancer cells to be more easily killed by targeted treatment.
Research indicates that Angelina Jolie's announcement that she had tested positive for BRCA1 influenced some women's intentions to seek out similar genetic testing.
Shorter course of whole breast radiation therapy for early stage breast cancer results in less toxicity and improved quality of life.
Cultural differences in the Latino community result in unique stressors for these patients after a cancer diagnosis. This study identified some of those stressors.
Many breast cancer survivors in Appalachia neglect taking critical follow-up treatment, even though their insurance would cover the cost, a study has found.
Depression may increase the intensity of postoperative acute pain in women with breast cancer.
Single-stage implant procedures after mastectomy may be a good option for selected patients.
Receptors that mediate activity of the female sex hormones (estrogen and progesterone) interact with DNA to control the growth of a large majority of breast cancers, research indicates.
Irradiation of regional nodes in patients with stage I-III breast cancer has a minimal effect on overall survival.
ASCO 2015: 12-week dosing schedule of zoledronic acid is noninferior to a more-frequent schedule of every 4 weeks.
Magnetic resonance imaging (MRI) and near-infrared spectral tomography (NIRST) is feasible and more accurate than MRI alone
There is no clinically relevant evidence of an association between opioid prescriptions and breast cancer recurrence.
Breast cancer survivors who experience pain or discomfort during sexual intercourse may benefit from applying liquid lidocaine to the vulvar area.
More evidence that two classes of generic drugs (aromatase inhibitors and bisphosphonates) reduce the risk of death in early breast cancer.
Aromatase inhibitors significantly decrease the risk of death in postmenopausal women with estrogen receptor-positive breast cancer.
Some women who undergo additional radiation along with whole-breast irradiation may be at a reduced risk of breast cancer recurrence.
Contrary to popular expectations, the rates of advanced breast cancer have not generally declined in a number of countries where mammography screening is employed.
State regulations of health insurance and practitioners are significantly associated with time receive breast or colorectal cancer diagnoses.
Survivors of breast cancer who also have a family history of breast cancer were found to experience more weight gain in a four-year period than were cancer-free women.
Researchers have found that spending more leisure time sitting was associated with an increased risk for developing cancer in women.
Scientists have discovered a new protein which triggers the growth of blood vessels in breast cancer tumors that have spread to the brain.
A recent study examined both attitudes and cultural perspectives of Latinas undergoing chemotherapy for breast cancer.
Pretreatment cytokine levels are associated with reduced memory performance among newly diagnosed patients with post-menopausal breast cancer.
Tamoxifen with ovarian function suppression versus tamoxifen alone as an adjuvant treatment for premenopausal breast cancer: a meta-analysis of published randomized controlled trials
[OncoTargets and Therapy] This article examines possible survival benefits of ovarian function suppression (OFS) when combined with adjuvant tamoxifen treatment for breast cancer in premenopausal women.
No significant difference in breast cancer deaths seen in counties with higher screening and detection rates.
Investigators have discovered that the death-associated protein kinase 1 (DAPK1) is actually essential for growth in breast and other cancers with mutations in the TP53 gene.
The stress hormones often used to treat the side effects of chemotherapy could have the side effect of making effective cancer drugs fail sooner in some women with breast cancer, according to new research.
Selective use of biomarker testing for patients with breast cancer has the potential to save millions of dollars in health care spending without compromising care.
Clinical trial data suggests that postmenopausal women of above-average weight have an increased risk of breast cancer.
The percentage of patients with early stage breast cancer undergoing breast-conserving therapy (BCT) increased from 54.3% in 1998 to 60.1% in 2011, according to a recent report. Notably, nonclinical factors including socioeconomic demographics, insurance, and the distance patients must travel to treatment facilities persist as key barriers to the treatment.
Breast cancer patients with high levels of the protein activin-like receptor kinase (ALK1) in the blood vessels of their tumors were more likely to develop metastatic disease, according to a new study. This makes inhibition of the ALK1 pathway a possible new target for the treatment of metastatic breast cancer.
CHICAGO, IL—Functional subtyping with a multigene classifier resulted in 1 in 5 tumors being reclassified compared with conventional immunohistochemistry/fluorescent in situ hybridization (IHC/FISH) analysis. This study was presented at the 2015 American Society for Clinical Oncology (ASCO) Annual Meeting.
10% urea cream is superior to a newly introduced ointment containing various antioxidants at preventing hand-foot syndrome.
Randomized trial shows beneficial effect for yoga combined with meditation in breast cancer survivors.
The links between demographic, treatment, and socioeconomic factors and breast cancer survival were examined in a recent study.
Women diagnosed with breast cancer and treated with a one-week regimen of partial breast radiation after tumor removal saw no increase in cancer recurrence or difference in cosmetic outcomes.
The presence of extra body fat causes increased risk of diabetes and heart disease, and also increases the chances for breast cancer recurrence.
The discovery of an enzyme that facilitates the spread of breast cancer may enable clinicians to prevent secondary cancer.
Embryo cryopreservation after aromatase inhibitor treatment and ovarian stimulation preserves fertility for patients with breast cancer, according to a study published online.
Premenopausal women with breast cancer are at increased risk of dying if they smoke.
Expanded surgical margins during a partial mastectomy could be beneficial for patients, preventing further surgery.
The majority of women with early-stage breast cancer undergo imaging for metastatic cancer despite guidelines.
A false breast cancer diagnosis can have long-lasting psychological effects.
The number of patients that undergo breast-conserving therapy (BCT) has risen slowly in recent years, but many with early-stage disease still choose mastectomy.
Breast surgery performed at or shortly after a diagnosis of low-grade ductal carcinoma in-situ (DCIS) was not found to significantly impact patients' survival rate.
Rates of breast-conserving therapy for early-stage breast cancer have increased.
Poor sleep and snoring before breast cancer diagnosis is tied to poor survival outcomes.
Half of the women with breast cancer polled considered double mastectomy, but only a little more than a third knew the aggressive procedure doesn't up the chances of survival.
Women ages 50 to 69 years who attend mammography screening reduce their risk of dying from breast cancer by 40% compared with women who are not screened, according to the latest evidence.
A Norwegian breast cancer screening program has markedly reduced breast cancer mortality.
An increase in cases of male breast cancer to the growing list of cancers associated with rising obesity rates.
Obesity is associated with increased risk for invasive breast cancer in postmenopausal women.
A new research review indicates that breast screening in the 40s may not prevent breast cancer deaths, but the conclusion among researchers wasn't unanimous.
A new study found that prognosis after treatment for women with breast cancer with a family history of the disease is no worse than it is for other women with breast cancer.
Breast cancer patients are much less likely to have potentially lifesaving surgery if diagnosed as an emergency rather than via urgent GP referral.
Affordable Care Act has removed financial barriers to preventive services, including breast and colorectal cancer screening.
Adding palbociclib to standard hormone therapy may be more beneficial than hormone therapy alone for HR+/HER2− breast cancer, according to a new study.
Removing extra tissue can halve the chances of requiring a second surgery in breast cancer.
A blood test that involves examination of cell-free circulating DNA could be key to earlier detection of breast cancer metastases.
Breast surgery performed at or shortly after a diagnosis of low-grade ductal carcinoma in-situ (DCIS) experienced no difference in survival.
Depending on the type of cancer faced, the needs of survivors can vary.
Enzalutamide may be a viable alternative therapy over cytotoxic chemotherapy for individuals with triple-negative breast cancer, according to a study presented at the 2015 American Society of Clinical Oncology annual meeting.
Not all women with dense breasts have a high enough breast cancer risk to justify additional imaging after a normal mammogram, according to a recent study.
Early intervention should be offered to young women with breast cancer on ovarian function suppression and tamoxifen, who experience poorer quality of life (QOL) in the early survivorship period, according to a study presented at the 2015 American Society of Clinical Oncology Annual Meeting.
Letrozole significantly reduced the rate of late invasive breast cancer events in postmenopausal women who had completed 4+ years of adjuvant endocrine therapy for HR+ breast cancer, the LATER trial concluded at the 2015 American Society of Clinical Oncology (ASCO) Annual Meeting.
Outcome prediction for postmenopausal patients with node-positive HR+ early breast cancer can be improved using a diagnostic assay, potentially negating the need for adjuvant chemotherapy, according to a study presented at ASCO 2015.
Female breast cancer survivors may be able to lose weight through modest lifestyle changes.
New research indicates that men with naturally high levels of the female hormone estrogen may have a greater risk of developing breast cancer.
No difference seen in distant disease-free intervals for those with versus those without a positive family history, say researchers.
Women with luminal A subtype breast cancer, especially those older than 60 years, may not need radiation treatment if they are already taking hormone therapy.
A false breast cancer alarm may still result in severe psychological strain.
Magnetic resonance imaging (MRI) can provide vital information for predicting the odds of breast cancer development.
Low-income and women without insurance in states that are not expanding their Affordable Care Act (ACA) Medicaid coverage are less likely to receive breast and cervical cancer screenings.
Five-year risk plus breast density can best identify women at high risk for interval cancer.
- Study uses dog sledding to demonstrate benefits of adapted physical activities for children with cancer
- What are immune checkpoints and how do they work?
- Efficacy and safety of docetaxel for advanced non-small-cell lung cancer: A meta-analysis of Phase III randomized controlled trials
- Among patients with myeloma undergoing chemo, high exercise compliance linked with reduced fatigue
- Patients with advanced cancer prefer open, effective communication
- Religiousness and spirituality have a significant impact on cancer patients' overall health and outcomes
- Dietary intervention primes triple-negative breast cancer cells for targeted therapy
- Lung cancer patients who stop smoking live longer
- Review examines strategies for hospital room surface cleanliness
- Appropriate use of tomosynthesis mammography
- Counseling cancer survivors on family building options
- Imaging technique allows pediatric brain tumors to be classified noninvasively at diagnosis
- Antibiotic use was associated with increased risk for some cancers
- ADT impacts mood of patients with prostate cancer, as perceived by partners
- Varubi approved for nausea and vomiting associated with cancer chemo
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