A study finds that report that overall outcomes and prognosis have significantly improved over time for women aged 40 years and younger with breast cancer who undergo breast conserving surgery, and the procedure should be recommended to these patients.
Partial-breast and reduced-dose radiotherapy was found to be noninferior in preventing local relapse compared with whole-breast radiation therapy in patients with early stage breast cancer with a lower-than-average risk of relapse.
[OncoTargets and Therapy] This research reviews available data on the role of the HER2 pathway in breast cancer and on the different targeted agents for the treatment of patients with early-stage HER2-positive disease, with a particular focus on neratinib.
A Systematic Literature Review Exploring the Prevalence of Post-traumatic Stress Disorder and the Role Played by Stress and Traumatic Stress in Breast Cancer Diagnosis and Trajectory
[Breast Cancer: Targets and Therapy] This research examines literature regarding the prevalence of PTSD in breast cancer patients and reviews mechanisms by which stress impacts cancer risk.
Moderate-to-vigorous physical activity was found to improve working memory and executive function in survivors of breast cancer.
Use of antiperspirant or deodorant does not adversely affect potential for dermal toxicity or surface concentrations of aluminum in the axilla in women undergoing radiation therapy for breast cancer.
Many women with breast cancer with genetic variants of uncertain significance (VUS) undergo testing and bilateral mastectomy without receiving genetic counseling.
Disease-Free Survival After Breast Cancer Comparable With Exemestane, Sequential Tamoxifen/Exemestane
A 10-year follow-up study finds disease-free survival (DFS) comparable with exemestane and sequential tamoxifen/exemestane in patients with HR-positive breast cancer.
Supplementation with vitamin D3 in premenopausal women does not have a significant effect on breast density percentage, nor does it reduce breast cancer risk.
CDK4/6 inhibitors, which block the activity of regulatory enzymes, are tolerated fairly well in patients with cancer; however, oncology nurses should be aware of some strategies that minimize their adverse effects.
Although a strong correlation between breast cancer diagnosis and stress has been noted — particularly in the form of posttraumatic stress disorder (PTSD) — there is no demonstrable evidence to suggest a direct causal relationship between them.
Many women with breast cancer with genetic VUS undergo testing and bilateral mastectomy (BLM) without ever receiving genetic counseling.
Fat grafting provides benefits to women with breast cancer considering their options for postmastectomy breast reconstruction, even though this study shows that patient-reported outcomes are similar among women who did and did not undergo the procedure.
A report on adherence to NCCN Guidelines found that, contrary to guideline recommendations, many asymptomatic patients with stage I/II breast cancer undergo chest CT for pulmonary nodules.
Two recent studies examined the benefits of using a 3D bioabsorbable marker to indicate the tumor bed in women with breast cancer who underwent breast conserving surgery (BCS).
Risk assessment study for carriers of the BRCA1/2 mutation identified the factors that influence their risk of developing breast cancer, ovarian cancer, or contralateral breast cancer.
Screening mammography programs increased early detection of tumors, improving outcomes for those women; however, these programs also increased detection of tumors that would never pose a clinical problem.
Regular aspirin use is associated with a lower risk of breast cancer among women with diabetes, a recent study from Taiwan has shown.
Ethnic Differences, Cultural Barriers Negatively Impact Mammography Follow-up Among Asian Ethnic Groups
Follow-up after abnormal results on mammography is more likely to be delayed among Asian American women compared with white women, and varies between different Asian ethnicities.
Changes in Pulmonary Function Tests in Breast Carcinoma Patients Treated With Locoregional Post-mastectomy Radiotherapy: Results of a Pilot Study
[Breast Cancer: Targets and Therapy] The goal of this research was to evaluate the acute changes in PFTs in breast carcinoma patients who received adjuvant chemotherapy and were treated with PMRT including SC regions.
Women with breast cancer who received capecitabine after adjuvant epirubicin had better quality of life (QOL) compared with those who received CMF after adjuvant therapy.
Breast cancer survivors who received taxane-based chemotherapy for their disease are at increased risk for falls due to CIPN and treatment-associated effects on balance and gait.
Community-based, interventionist-guided weight loss program was efficacious for early-stage survivors.
Adding a second HER2-blocker to standard care therapy after surgery for HER2-positive breast cancer may be modestly beneficial for some women.
A patient survey was designed to examine patient views of their initial breast cancer diagnosis process and care management.
Participants with high risk of depression reported lower mood disturbance, anxiety, depression following intervention.
Ovarian function recovery (OFR) in women with chemotherapy-induced ovarian function failure decreases residual 5-year disease-free and overall survival.
A questionnaire added to intake forms at a breast cancer imaging center identified women with BRCA mutations who might otherwise have been missed.
A tool called iCanDecide prepares patients for making decision about treatment better than static online information, study finds.
Male breast cancer patients are less likely than their female counterparts to receive adjuvant hormone therapy and postlumpectomy radiation.
Biosimilars and originator trastuzumab neoadjuvant therapy had a comparable effect on pathologic complete response rates.
'Conquer Fear' decreased fear among survivors of breast and colorectal cancer and melanoma compared with relaxation techniques.
Tai chi is as effective as cognitive behavioral therapy for insomnia (CBT-I) for the treatment of insomnia in breast cancer survivors.
Even a small glass of wine each day can increase the odds of both premenopausal and postmenopausal breast cancer, evidence suggests.
An educational counseling intervention delivered by nurses directly to spouses of women with breast cancer improved marital communications and patients' appraisal of their spouse's interpersonal support.
Trends in caregiver involvement in home-based patient care are introducing new avenues for symptom management and improved health-related quality of life for patients undergoing chemotherapy for advanced breast cancer.
Weekly journaling with oncology nurse review ensures adherence to skin self-care in women undergoing radiation therapy for breast cancer.
Canadian investigators sought to understand the factors that influence the treatment choices of women with early-stage breast cancer.
High Levels of Negative Emotions in Breast Cancer Survivors Motivates Exercise, Increases Cortisol Levels
Negative emotions were shown to motivate breast cancer survivors to engage in moderate-to-vigorous exercise, and can increase their daytime levels of cortisol.
Seven interdisciplinary cancer and bone societies released a position statement updating recommendations for limiting bone loss and fracture risk in patients with early-stage breast cancer undergoing treatment with AIs.
A texture analysis technique improved classification of different types of breast tissue imaged with optical coherence microscopy.
Women with triple-negative or HER2-positive breast cancer who achieve a pathologic complete response from neoadjuvant chemotherapy may be able to avoid follow-up breast or lymph node surgery.
Researchers manipulated triple-negative breast cancer cells to make them susceptible to conventional antiestrogen therapy for breast cancer.
New Criteria for Appropriate Use of Bone Scintigraphy to Diagnose and Manage Prostate and Breast Cancer
Several clinical societies came together to create appropriate use criteria for the use of bone scintigraphy in patients with prostate and breast cancer.
Given recent guideline changes and lack of consistency in guidelines, a survey sought to highlight how primary care physicians recommend breast cancer screening to their patients.
Low Acculturated Latina Women Reported Breast Cancer Treatment Experience Differently Than Other Groups
Researchers found that low acculturated Latina women were moderately less satisfied with surgeon and oncology communication compared with other racial and ethnic groups.
Researchers compared cost data and complications between mastectomy with reconstruction and other guideline-based treatments for patients with early-stage breast cancer.
Limited use of genetic counselors and high rate of double mastectomy in women at average risk with early-stage breast cancer illustrate that understanding of genetic testing results is limited.
Study finds patients are not more likely to report dissatisfaction, seek a second opinion, or change doctors due to physician recommendations against CPM.
Physical activity is proven to improve both physical and mental effects of cancer diagnosis and treatment, even if the activity needs to be modified to fit the patient's current abilities.
Out of 7 nationality groups studied, only Japanese women didn't have an overall increase in the disease.
[Breast Cancer: Targets and Therapy] This research discusses the management options for incidents of mastectomy skin flap necrosis (MSFN).
This fact sheet reviews the types of mammograms, false-positive and false-negative results, digital mammography, and tomosynthesis mammography.
Reporting of overall immediate breast reconstruction and of racial disparities varies significantly between SEER and 2 large US databases.
The proportion of women with invasive early-stage unilateral breast cancer electing CPM has increased significantly, and varies across US states.
Absolute risks from radiation therapy for women with breast cancer who continue to smoke could exceed the absolute benefit of the therapy.
Genetic testing for BRCA gene mutation is increasingly undertaken by women unaffected by breast and/or ovarian cancers.
Follow-up via mobile app similar to in-person postoperative visits for low-risk ambulatory patients after breast reconstruction.
Risk calculator assesses patients for risk of persistent pain after breast cancer surgery (PPBCS).
Risk associated with radiotherapy for breast cancer is substantially reduced with smoking cessation.
Genetic signatures similar to BRCA1/BRCA2 mutations could make PARP inhibition a treatment option for some breast cancers.
Health care costs lower for early-stage breast cancer when adjuvant radiation therapy follows evidence-based guidelines.
Arm Lymphoscintigraphy After Axillary Lymph Node Dissection or Sentinel Lymph Node Biopsy in Breast Cancer
[OncoTargets and Therapy] This research examines the lymphatic flow in the arm following breast cancer surgery and axillary lymph node dissection (ALND) versus sentinel lymph node biopsy (SLNB) using lymphoscintigraphy (LS).
A significantly shorter course of trastuzumab achieved both improved outcomes for patients and cost savings for the UK National Health Service.
Follow-up MRI screening in women at high risk of breast cancer was improved when patients were informed directly of their potential risks and options.
This fact sheet examines possible relationships between use of antiperspirants or deodorants and cancer risk.
Leflunomide, an immunosuppressor FDA-approved for rheumatoid arthritis, is effective against breast cancer in mouse study.
Pregnancy around the time of, or after, diagnosis of breast cancer is not associated with an increased risk of death.
Despite the known benefits of physical activity for breast cancer survivors, a large proportion of this population continues to be physically inactive after treatment.
Zoledronic acid and clodranate are the recommended bisphosphonates for the adjuvant treatment of postmenopausal patients with breast cancer.
Quantity and quality of skeletal muscle is a more accurate measure for determining dose and of potential treatment-related toxicity in patients receiving chemotherapy for early-stage breast cancer.
Digital mammography has improved breast cancer detection, increased biopsies.
Treatment with radiation therapy for invasive breast cancer may place East Asian women at a greater risk of developing second primary lung cancer (SPLC).
[Breast Cancer: Targets and Therapy] This research examines possible risk factors and effectiveness of treatments for docetaxel-associated myalgia-arthralgia syndrome.
Digital breast tomosynthesis used with full-field digital mammography has the potential to reduce call-back rates for breast examinations.
MRI screening has high specificity and positive predictive value in average risk women.
Internet-based cognitive behavioral therapy has positive effects on sexual functioning in breast cancer survivors experiencing sexual dysfunction.
Painter and tattoo artist David Allen has used his skills to transform breasts scarred by surgical reconstruction into works of art.
Patients with hormone receptor-positive, HER2-negative, axillary lymph node-negative breast cancer who have a recurrence score of 11 to 25 may not benefit from chemotherapy.
HER-2 enriched subtype predicts for HER2 blockade benefit with lapatinib and trastuzumab
Risk of chemotherapy-induced hair loss common to breast cancer therapy may be reduced with the use of scalp-cooling device.
Adjuvant trastuzumab following chemotherapy significantly improves long-term disease-free survival in women with HER2-positive early breast cancer, according to study data.
[Breast Cancer: Targets and Therapy] This research examines predisposing factors, prevention, and therapy of myalgia-arthralgia syndrome (M-AS).
Risk for all-cause mortality is lower among older women treated for DCIS.
High mammographic breast density is a risk factor for primary breast cancer. In this study, a potential correlation with contralateral breast cancer was investigated.
In this study, the impact of cholesterol-lowering medications on breast cancer recurrence in women receiving adjuvant endocrine therapy was investigated.
Fewer black BRCA carriers undergo salpingo-oophorectomy to reduce their risk for breast cancer than their Hispanic and non-Hispanic white counterparts.
Women who experience a false positive mammogram were more likely to delay their subsequent screening, potentially increasing the risk of having late stage breast cancer at diagnosis.
Investigators from the Netherlands present their research findings on survival in women with early stage breast cancer who underwent breast-conserving therapy vs mastectomy at the 2017 European Cancer Congress.
Might a Chemical from Celery and Broccoli One Day Yield a New Drug to Prevent Breast Cancer Metastasis?
Investigators report on their findings from preclinical studies of luteolin injections to prevent lung metastases of triple-negative breast cancer.
Discovered link between inflammation and overexpression of CCL2 hints at potential of anti-inflammatory medications as a breast cancer preventive in women with dense-tissue breasts.
Lifelong soy consumption improves tamoxifen response in women with breast cancer; however, adding soy to diet after initiating tamoxifen therapy may not provide the same benefits.
Gastric and Colon Metastasis From Breast Cancer: Case Report, Review of the Literature, and Possible Underlying Mechanisms
[Breast Cancer: Targets and Therapy] This research presents a case report of patient with gastrointestinal metastases from breast cancer.
Although significant variation in care persists, underuse and misuse of adjuvant endocrine therapy for breast cancer has decreased since 2004.
Administering chemotherapy to African-American women with breast cancer prior to surgery may help improve their survival.
Researchers report that clinicians may want to start collecting toxicity data routinely and offering early interventions to patients with breast cancer.
Letrozole was not superior to anastrazole with respect to efficacy or safety in postmenopausal women with HR-positive, node-positive early breast cancer.
Researchers sought to determine the noninferiority of continuing zoledronic acid for an additional year every 12 weeks vs zoledronic acid every 4 weeks in patients receiving monthly intravenous zoledronic acid and/or pamidronate disodium for 1 year or longer.
New Understanding of Mechanisms Revealed in Development of Breast Cancer and Resistance to Treatment
Researchers explore the biologic influences of breast cancer development and resistance to treatment.
In this study, researchers quantified the frequency, severity, and burden of treatment-associated toxicities in patients with early-stage invasive breast cancer using patient surveys.
- FDA Grants Approval to Bevacizumab-awwb as First Biosimilar for Anticancer Therapy
- Efficacy of Octreotide LAR, Lanreotide in Management of Carcinoid Tumors
- Multivitamin Use May Reduce Risk of Chemo-Induced Neuropathy
- Overall Survival in Advanced Melanoma Improved With Nivolumab, Ipilimumab Combination
- Adjuvant Durvalumab Therapy May Prolong Progression-free Survival in NSCLC
- Invisible Burdens: The Complex Needs of Caregivers of Patients With Brain Cancer
- Cannabis Reduces Response Rate to Immunotherapy for Cancer
- Perioperative Blockade of Pathways May Improve Outcomes in Breast Cancer
- Zika Virus Preferentially Targets Glioblastoma Stem Cells
- Daratumumab Infusion-Related Reactions Managed by Pre/Postinfusion Medications
- Cost of Care Significantly Increased With Carcinoid Syndrome in NETs
- Treating Intractable Hiccups in Advanced Cancer, Palliative Care Setting
- Severe Mental Illness May Worsen Breast Cancer Survival Outcomes
- Imaging Management of Breast Density, a Controversial Risk Factor for Breast Cancer
- Efficacy of Octreotide LAR, Lanreotide in Management of Carcinoid Tumors
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