Biomarker for aggressive, basal-like breast cancer identified

A biomarker strongly linked to basal-like breast cancer has been identified.

Black Women's Health Study (BWHS) shows exercise improves breast cancer risk for African American women

This recently published study found strong evidence linking physical exercise to a lower rate of breast cancer in African American women, a group in which previous evidence has been lacking.

Bone drugs may not protect osteoporotic women from breast cancer

Osteoporosis drugs known as bisphosphonates may not protect women from breast cancer as had been thought, according to a new study.

Endogenous hormones improve breast cancer risk prediction

Endogenous hormones improve breast cancer risk prediction

Inclusion of endogenous hormones in prediction models improves prediction of invasive breast cancer risk in postmenopausal women, according to a study.

Postmenopausal breast cancer risk drops off after starting regular physical activity

Postmenopausal women who in the past 4 years had undertaken regular physical activity equivalent to at least 4 hours of walking per week had a lower risk for invasive breast cancer compared with women who exercised less

Mutations in the PALB2 gene increases risk of breast cancer by age 70 years

The PALB2 gene is potentially one of the most important genes associated with breast cancer after the BRCA1/2 genes.

NSAIDs may lower breast cancer recurrence in overweight and obese women

Recurrence of hormone-related breast cancer was reduced by 50% in overweight and obese women who regularly used aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs), according to newly published data.

Dasatinib may be effective against several cancers

Dasatinib may be effective against several cancers

Dasatinib shows promise for treating skin, breast and several other cancers.

MRI more effective at detecting recurrent breast cancer

MRI more effective at detecting recurrent breast cancer

MRI detects 18.1 additional cancers after negative findings with mammography and ultrasonography per 1,000 women.

Bisphosphonate use may not prevent breast cancer

Bisphosphonate use may not prevent breast cancer

Data from two randomized controlled trials suggest that bisphosphonate use does not protect against postmenopausal breast cancer, according to research.

NSAIDs linked to decreased breast cancer recurrence among obese women

NSAIDs linked to decreased breast cancer recurrence among obese women

In overweight women, aspirin or other drugs might make certain breast cancers more treatable.

Expressive writing improves health outcomes for breast cancer survivors

Writing down fears, emotions, and the benefits of a cancer diagnosis may improve health outcomes for Asian American survivors of breast cancer, according to a new study. The research investigated methods of reducing the psychological burden among minority patients, particularly among breast cancer survivors.

Cancer categories recast in largest-ever genomic study

New research suggests that cancer would be more accurately diagnosed in 1 of every 10 patients if their tumors were defined by cellular and molecular criteria rather than by the tissues in which they originated, and that this information, in turn, could lead to more appropriate treatments.

Mammography benefits women older than 75 years

Mammography-detected breast cancer is associated with a shift to earlier stage diagnosis in older women, subsequently reducing the rate of more advanced, difficult-to-treat cases. Researchers said the findings lend support to regular mammography screening in women age 75 years and older.

New mutations may increase breast cancer risk

New mutations may increase breast cancer risk

Mutations in PALB2 and germline mutations in the multiple endocrine neoplasia type 1 (MEN1) tumor-suppressor gene causing MEN1 correlate with increased breast cancer risk, according to two studies.

Acupuncture improves quality of life for breast cancer patients taking aromatase inhibitors (AIs)

Electroacupuncture (EA) produces significant improvements in fatigue, anxiety, and depression in as little as 8 weeks for patients with early stage breast cancer experiencing joint pain related to the use of aromatase inhibitors to treat breast cancer.

Exercise reduces the risk of breast cancer in older women

Exercise reduces the risk of breast cancer in older women

Older women intent on keeping breast cancer at bay may want to start and maintain a regular exercise regimen.

Women 75+ may still benefit from routine mammograms

Women 75+ may still benefit from routine mammograms

Breast cancer survival has been found to be better in women whose cancer was detected by mammography.

Acupuncture reduces comorbid symptoms of cancer pain

Acupuncture reduces comorbid symptoms of cancer pain

Electroacupuncture may reduce comorbid symptoms of pain in women with breast cancer who have aromatase inhibitor-related arthralgia, according to research.

Ginger as a treatment for breast cancer

Ginger as a treatment for breast cancer

Research published in the Journal of Biomedicine and Biotechnology suggests that ginger may be a promising breast cancer treatment.

Recent use of some birth control pills may increase breast cancer risk

Recent use of some birth control pills may increase breast cancer risk

Women who recently used birth control pills containing high-dose estrogen and a few other formulations had an increased risk for breast cancer, whereas women using some other formulations did not, according to recent data.

Gel formulation of tamoxifen significantly reduces side effects related to the oral formulation

A gel form of tamoxifen applied to the breasts of women with noninvasive breast cancer reduced the growth of cancer cells to the same degree as the drug taken in oral form but with fewer side effects.

Mammograms may be beneficial for women over 75

Mammograms may be beneficial for women over 75

According to a study published in Radiology, women over 75, a population not typically included in mammography screening effectiveness studies, may benefit from mammograms.

Possible target for immunotherapy in early stage breast cancer identified

A new molecular analysis tool accurately detected the level of an important target for immunotherapy in early stage breast cancers.

Breast cancer survivors benefit from writing about their experiences

Breast cancer survivors benefit from writing about their experiences

A new study demonstrated that writing about emotionally difficult events, such as a cancer diagnosis, might improve outcomes for some breast cancer survivors.

Sleeping in darkness boosts breast cancer drug effectiveness

Sleeping in darkness boosts breast cancer drug effectiveness

Keeping a light on at night can suppress the body's production of a hormone called melatonin, possibly reducing the effectiveness of the breast-cancer drug tamoxifen, a study suggests.

Exposure to dim light at night may lead to tamoxifen resistance in breast cancer

For rats bearing human breast tumors, exposure to dim light at night made the tumors resistant to the breast cancer drug tamoxifen, according to recently published data.

Navigators can help guide patients with breast cancer through care

Navigators can help guide patients with breast cancer through care

A team of researchers from Boston University School of Medicine sought to determine the impact of patient navigators on the care of low-income and African-American women with breast cancer.

Electroacupuncture improves quality of life for breast cancer patients using AIs

Electroacupuncture improves quality of life for breast cancer patients using AIs

Use of electroacupuncture produces significant improvements in fatigue, anxiety, and depression in as little as 8 weeks for patients with early stage breast cancer patients experiencing joint pain related to the use of AIs to treat breast cancer.

Genes linked to breast cancer in East Asian women identified

A new study has identified three genetic changes in East Asian women linked to an increased risk of breast cancer.

Rethinking Breast Cancer Screening: Ultra FAST Breast MRI [EDITORIALS]

Rethinking Breast Cancer Screening: Ultra FAST Breast MRI [EDITORIALS]

Breast cancer screening is once again controversial. In this editorial, the author discusses new research demonstrating the effectiveness of an MRI imaging technique called first postcontrast subtracted T1-weighted image (FAST).

Standard of care for delivering bisphophonates

Standard of care for delivering bisphophonates

What is the preferred delivery protocol for breast cancer adjuvant bisphosphonates?

Genetics is the dominant risk factor for familial breast, prostate, and colorectal cancers

Genetics is the dominant risk factor for familial breast, prostate, and colorectal cancers

A study of people who were adopted identified genetics as the dominant risk factor in familial breast, prostate, and colorectal cancers.

No change seen in breast cancer detection despite increased Medicare costs for screening

Breast cancer screening costs for Medicare patients skyrocketed between 2001 and 2009, but the increase did not lead to earlier detection of new breast cancer cases, according to a study.

Hormones after breast cancer: natural steroid hormones may be safe, effective

Hormones after breast cancer: natural steroid hormones may be safe, effective

A new study suggests a safe and effective role for natural steroid hormones in treating postmenopausal breast cancer, with fewer detrimental side effects and improved health profile than with standard antihormone therapies.

New blood test predicts risk of nonhereditary breast cancer

New blood test predicts risk of nonhereditary breast cancer

A simple blood test is currently in development that could help predict the likelihood of a woman developing breast cancer, even in the absence of a high-risk BRCA1 gene mutation, according to new research.

Gene marker may help predict breast cancer response to tamoxifen

Gene marker may help predict breast cancer response to tamoxifen

Researchers have identified genes that may help predict whether a patient with estrogen receptor (ER)-positive breast cancer is likely to benefit from tamoxifen therapy.

Genetic profile and potential drug susceptibility of breast cancer cells revealed by CTCs

Circulating tumor cells captured with a microchip-based device can be cultured to establish cell lines for genetic analysis and drug testing.

Parabens in Cosmetics: What Is the Connection to Cancer?

Parabens in Cosmetics: What Is the Connection to Cancer?

Current studies indicate that the levels of parabens used in cosmetics are safe (typical levels are 0.1% to 0.3%); however, many believe a relationship to cancer exists, particularly breast cancer. The furor came about after a 2004 study reported finding parabens in the breast tissue of 20 women.

Update of staging criteria for breast cancer diagnosis recommended

New findings paint a relatively optimistic picture of women's chances of surviving a subset of breast cancers that have spread to the chest wall or skin, but not beyond.

Scientists bring personalized medicine for breast cancer one step closer

Scientists bring personalized medicine for breast cancer one step closer

The era of personalized medicine for breast cancer may be just around the corner, thanks to recent advances by USC Stem Cell researcher Min Yu and scientists at Massachusetts General Hospital and Harvard Medical School.

Cultured circulating tumor cells reveal genetic profile of breast cancer cells

Cultured circulating tumor cells reveal genetic profile of breast cancer cells

Researchers have created a microchip device that can capture circulating tumor cells, in order to track ongoing genetic mutation within a tumor.

Protein pushes breast cancer cells to metastasize

Using an innovative tool that captures heretofore hidden ways that cells are regulated, scientists have identified a protein that makes breast cancer cells more likely to metastasize.

Breast cancer screening costs on the rise for Medicare patients

Breast cancer screening costs on the rise for Medicare patients

Although use of newer technologies and costs associated with breast cancer screening have increased, no change in stage at diagnosis has been observed in Medicare beneficiaries.

Skin gel helps fight against breast cancer

Skin gel helps fight against breast cancer

A gel containing the drug tamoxifen and applied to the skin was as effective as the pill form in reducing the growth of breast cancer cells in women with noninvasive cancer.

Mammography has led to fewer late-stage breast cancers

In the 30 years since mammography was introduced, late-stage breast cancer incidence has decreased by 37%, according to a new study. The analysis, from the University of Michigan Comprehensive Cancer Center in Ann Arbor, takes into account an observed underlying trend of increased breast cancer incidence present since the 1940s

Latest findings give optimistic picture of breast cancer survival odds

Latest findings give optimistic picture of breast cancer survival odds

New findings from Fox Chase Cancer Center paint a relatively optimistic picture of women's chances of surviving a subset of breast cancers that have spread to the chest wall or skin.

CTCs can be captured and cultured for genetic analysis and drug testing of breast cancer cells

CTCs can be captured and cultured for genetic analysis and drug testing of breast cancer cells

A microchip-based device developed at the Massachusetts General Hospital (MGH) Center for Engineering in Medicine and the MGH Cancer Center can capture circulating tumor cells (CTCs). The CTCs can then be cultured to establish cell lines for genetic analysis and drug testing.

Inhibitor of cholesterol biosynthesis may have potential as breast cancer treatment

A compound initially developed as a treatment for high cholesterol not only halts the progression of breast cancer, but also can kill cancer cells.

ESC: Hyperlipidemia increases breast cancer risk

ESC: Hyperlipidemia increases breast cancer risk

The presence of hyperlipidemia has been linked to 1.64-fold increased risk of breast cancer.

Barriers to obtaining gene expression profiling tests increase their perceived value among patients

Barriers to obtaining gene expression profiling tests increased their perceived importance among patients with early breast cancer (estrogen-receptor positive [ER+], human epidermal growth-factor receptor 2 negative [HER2-], and node negative) who were deciding whether to have chemotherapy after surgery, according to a new study from Canada.

Researchers suggest updating the staging criteria for breast cancer diagnoses

Researchers suggest updating the staging criteria for breast cancer diagnoses

Study findings from Fox Chase Cancer Center offer relatively optimistic news for women with breast cancer whose disease has spread to the chest wall or skin, but not beyond.

IUDs may up breast cancer risk

IUDs may up breast cancer risk

A new study has found that the levonorgestrel-releasing intrauterine system, or progesterone-releasing IUD, may be associated with a higher than expected incidence of breast cancer.

Telephone call is effective support when breast cancer treatment includes weight loss

A series of simple telephone calls can make a profound difference in helping women with breast cancer to meet their treatment goals for weight loss.

HER2 testing may incorrectly classify some women with breast cancer

A recent study of HER2 testing in a large cohort of women with breast cancer found important limitations in testing methods.

New markers for breast cancer may assist diagnoses

New markers for breast cancer may assist diagnoses

The fight against breast cancer is never-ending, but Virginia Tech researchers have found additional diagnostic markers that may aid clinicians to better forecast and prevent the disease.

High sugar intake may increase breast cancer risk

High sugar intake may increase breast cancer risk

The more sugary drinks a woman consumes, the greater her risk for breast cancer, a study has found.

State law requires advising women of dense breast tissue, breast cancer risk

State law requires advising women of dense breast tissue, breast cancer risk

Massachusetts legislators introduced a bill that requires doctors to tell patients when a mammogram reveals that the woman has breast dense tissue.

Combination imaging helps breast tumor differentiation

Combination imaging helps breast tumor differentiation

The use of new technique, which includes four approaches, could reduce unnecessary breast biopsies.

Cholesterol levels may be tied to breast cancer risk

Cholesterol levels may be tied to breast cancer risk

High cholesterol levels may increase a woman's risk of developing breast cancer, a large new British study reports.

Does frailty influence the use of adjuvant hormone treatment in older breast cancer patients?

Does frailty influence the use of adjuvant hormone treatment in older breast cancer patients?

Many patients older than 65 years with localized breast cancer are eligible for adjuvant hormonal therapy, but little is known about why patients start and stop treatment.

Benefits of trastuzumab outweigh the risk of harm in advanced breast cancer

A new systematic review shows that treatment with the breast cancer drug trastuzumab is associated with prolonged survival in women with advanced breast cancer, but the risk of developing heart problems also increases.

Screening mammography costs soar for seniors

Screening mammography costs soar for seniors

In a comparison of data from 2001-2002 and 2008-2009, the use of screening mammography for Medicare-enrolled women without a history of breast cancer was consistent, at approximately 42%. However, the increase in use of more expensive digital mammography technology has resulted in higher costs ($115 vs $73 per mammogram).

Bisphenol A Triggers Changes in Rats That May Lead to Breast Cancer

Bisphenol A Triggers Changes in Rats That May Lead to Breast Cancer

New research presents another cause for concern in regard to the chemical bisphenol A (BPA). The study is the first to examine what impact BPA has on the DNA of mammary glands as they age.

Breast cancer detection hasn't increased in line with costs

Breast cancer detection hasn't increased in line with costs

Medicare's mammography costs increased by almost 50% over a 7-year period while the breast cancer detection rate and stage at diagnosis did not change, according to a study.

Racial disparities in breast cancer care extends to lymph node biopsy

Racial disparities in breast cancer care extends to lymph node biopsy

A study from the University of Texas MD Anderson Cancer Center reveals a disparity in use of sentinel lymph node biopsy between black and white women.

Combination imaging can distinguish malignant and benign breast tumors

Combination imaging can distinguish malignant and benign breast tumors

Imaging breast tumors using four approaches together can better distinguish between malignant breast tumors and those that are benign, compared with imaging using fewer approaches.

Drug resistance reversed when tamoxifen is paired with antimalarial agent

The antimalarial drug hydroxychloroquine (HCQ) reverses resistance to tamoxifen in mice, according to investigators.

Leukemia gene leads to potential target for triple-negative breast cancer treatment

Leukemia gene leads to potential target for triple-negative breast cancer treatment

Scientists have discovered that a gene previously linked to leukaemia could provide an urgently needed target for the development of drugs to treat patients with 'triple negative' breast cancer.

Digital mammography with tomosynthesis lowers recalls

Digital mammography with tomosynthesis lowers recalls

Compared with digital mammography alone, the combination of digital mammography and tomosynthesis increases cancer detection and reduces false-positive results, according to research.

A career change to radiation oncology nursing

A career change to radiation oncology nursing

What is the best approach to learning more about the field of Radiation Oncology?

Mammography has reduced numbers of late-stage breast cancers

Since mammography was introduced late-stage breast cancer incidence has decreased by 37%, according to a new study

African-American women more likely to be diagnosed with higher-risk breast cancer

African-American women frequently present with biologically less favorable subtypes of breast cancer, according to a research study.

Breast cancer gene needs protein partner to grow

Breast cancer gene needs protein partner to grow

A study has revealed that the gene Metadherin—which is implicated in promoting the spread of breast cancer tumors—only stimulates tumor growth when the protein made by the gene interacts with a second protein.

Molecular imaging visualizes novel way to knock down breast cancer

A recent innovation in breast cancer biomarkers seeks to visualize the HER3 receptor, which could mean more comprehensive breast cancer imaging and potential treatments.

Lymphedema awareness low in patients with breast cancer

Lymphedema awareness low in patients with breast cancer

Although they experienced classic symptoms of post-surgical lymphedema, many breast patients didn't recognize the condition as related to treatment.

Molecular breast imaging protocol unmasks more cancer in advanced cases

Patients with advanced breast cancer that may have spread to their lymph nodes could benefit from a more robust dose of a molecular imaging agent when undergoing lymphoscintigraphy.

Preoperative genetic testing steers surgical choice in breast cancer

Preoperative genetic testing steers surgical choice in breast cancer

Majority of BRCA mutation carriers opted for different surgery than initially planned by surgeon.

Limiting carbs may reduce breast cancer recurrence in some women

Limiting carbs may reduce breast cancer recurrence in some women

Reducing carbohydrate intake could reduce the risk of breast cancer recurrence among women whose tumor tissue is positive for the insulin-like growth factor-1 (IGF1) receptor, according to a new study.

BPA stimulates breast cancer cells growth

BPA stimulates breast cancer cells growth

A chemical commonly used in plastics, appears to increase the proliferation of breast cancer cells, according to Duke Medicine researchers.

Phone intervention helps women with breast cancer lose weight

Phone intervention helps women with breast cancer lose weight

Among postmenopausal women receiving letrozole as adjuvant therapy for breast cancer, a telephone-based weight loss intervention was effective in promoting weight loss.

Diet may impact breast cancer recurrence

Diet may impact breast cancer recurrence

Personalized dietary recommendations based on molecular characteristics of primary tumor tissue may be an effective strategy for breast cancer survivors, according to research.

Benefits of trastuzumab outweigh risk of harm for advanced breast cancer

In women with advanced (or metastatic) breast cancer, treatment with the breast cancer drug trastuzumab is associated with prolonged survival but also increases the risk of developing heart problems

Annual MRI and digital mammography effective for screening high-risk women

Annual MRI and digital mammography effective for screening high-risk women

Initial results indicate that annual magnetic resonance imaging (MRI) and digital mammography can form an effective screening program for women at high risk of breast cancer, according to research.

New test predicts if breast cancer will spread

New test predicts if breast cancer will spread

A test of tumor microenvironment of metastasis (TMEM) predicted risk of distant metastasis in estrogen receptor-positive and HER2-negative breast cancer, according to a new study.

Mammograms may significantly decrease breast cancer mortality

Mammograms may significantly decrease breast cancer mortality

In the latest major study to consider whether the dangers of mammograms outweigh the benefits, experts say the tests can reduce the chances of dying from breast cancer by nearly 30 percent.

Educational video reduces barriers to early detection of breast cancer

Educational video reduces barriers to early detection of breast cancer

A documentary film showcasing the stories of local women who survived breast cancer may help educate African American women in breast cancer risks and early treatment.

Aromatherapy reduces anxiety during breast biopsy

Aromatherapy reduces anxiety during breast biopsy

A study evaluating the effectiveness of aromatherapy as a complementary/alternative modality for reducing anxiety in women undergoing CNB was presented at the Oncology Nursing Society 39th Annual Congress.

Workshop prepares nurses to address sexual concerns of breast cancer survivors

Workshop prepares nurses to address sexual concerns of breast cancer survivors

Sexual health workshops increased nurse knowledge and confidence, allowing nurses to address sexual concerns of breast cancer survivors.

Four genes confirmed as increasing familial breast cancer risk

Four new genes have been added to the growing list of those known to cause increased breast cancer risk when mutated.

Breast cancer surgery trends in Canada similar to that in United States

Breast cancer surgery trends in Canada similar to that in United States

To better understand breast cancer surgery trends in Canada, researchers reviewed data from the Canadian Institute for Health (CHI) on 57,840 women who underwent breast cancer surgery between 2007 and 2010.

Gene mutation lowers breast cancer survival

Gene mutation lowers breast cancer survival

Women with a specific gene mutation have a higher risk of dying from a type of breast cancer, according to a study that raised prospects of targeted drugs.

Breast MRI discovering other suspect masses

Breast MRI discovering other suspect masses

When women undergo MRIs to check for breast cancer, the scans sometimes reveal suspicious masses elsewhere in the body, which can generate a lot of anxiety and require more testing.

Patient risk information improves mammogram interpretation

Patient risk information improves mammogram interpretation

A research group's findings demonstrate a role for risk profiling in the interpretation of mammograms. The new approach takes into account a woman's health risk profile, which may reduce both the number of missed cancers and false positives.

Breast cancer risk linked to higher red meat intake

Breast cancer risk linked to higher red meat intake

Risk could be reduced by substitution of other legumes or poultry for red meat.

Late-stage breast cancer less frequent in mammography era

Late-stage breast cancer less frequent in mammography era

There appears to have been a decrease in late-stage breast cancer in the mammography era, according to a study published online.

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