Breast-Conserving Surgery Recommended For Younger Women With Breast Cancer

Breast-Conserving Surgery Recommended For Younger Women With Breast Cancer

A study finds that report that overall outcomes and prognosis have significantly improved over time for women aged 40 years and younger with breast cancer who undergo breast conserving surgery, and the procedure should be recommended to these patients.

Adjuvant Partial Breast Radiotherapy Noninferior in Preventing Relapse in Local Breast Cancer

Adjuvant Partial Breast Radiotherapy Noninferior in Preventing Relapse in Local Breast Cancer

Partial-breast and reduced-dose radiotherapy was found to be noninferior in preventing local relapse compared with whole-breast radiation therapy in patients with early stage breast cancer with a lower-than-average risk of relapse.

Emerging Treatments for HER2-positive Early-stage Breast Cancer: Focus on Neratinib

Emerging Treatments for HER2-positive Early-stage Breast Cancer: Focus on Neratinib

[OncoTargets and Therapy] This research reviews available data on the role of the HER2 pathway in breast cancer and on the different targeted agents for the treatment of patients with early-stage HER2-positive disease, with a particular focus on neratinib.

A Systematic Literature Review Exploring the Prevalence of Post-traumatic Stress Disorder and the Role Played by Stress and Traumatic Stress in Breast Cancer Diagnosis and Trajectory

A Systematic Literature Review Exploring the Prevalence of Post-traumatic Stress Disorder and the Role Played by Stress and Traumatic Stress in Breast Cancer Diagnosis and Trajectory

[Breast Cancer: Targets and Therapy] This research examines literature regarding the prevalence of PTSD in breast cancer patients and reviews mechanisms by which stress impacts cancer risk.

Physical Activity Improves Cognitive Function for Breast Cancer Survivors

Physical Activity Improves Cognitive Function for Breast Cancer Survivors

Moderate-to-vigorous physical activity was found to improve working memory and executive function in survivors of breast cancer.

Deodorant, Antiperspirant Use During Radiation Therapy for Breast Cancer Not Detrimental

Deodorant, Antiperspirant Use During Radiation Therapy for Breast Cancer Not Detrimental

Use of antiperspirant or deodorant does not adversely affect potential for dermal toxicity or surface concentrations of aluminum in the axilla in women undergoing radiation therapy for breast cancer.

Bilateral Mastectomy Without Proper Genetic Counseling

Bilateral Mastectomy Without Proper Genetic Counseling

Many women with breast cancer with genetic variants of uncertain significance (VUS) undergo testing and bilateral mastectomy without receiving genetic counseling.

Disease-Free Survival After Breast Cancer Comparable With Exemestane, Sequential Tamoxifen/Exemestane

Disease-Free Survival After Breast Cancer Comparable With Exemestane, Sequential Tamoxifen/Exemestane

A 10-year follow-up study finds disease-free survival (DFS) comparable with exemestane and sequential tamoxifen/exemestane in patients with HR-positive breast cancer.

Vitamin D3 Supplementation Has No Impact on Breast Density Percentage, Breast Cancer Risk

Vitamin D3 Supplementation Has No Impact on Breast Density Percentage, Breast Cancer Risk

Supplementation with vitamin D3 in premenopausal women does not have a significant effect on breast density percentage, nor does it reduce breast cancer risk.

A Review of CDK4/6 Toxicities and Interactions Management in Breast Cancer

A Review of CDK4/6 Toxicities and Interactions Management in Breast Cancer

CDK4/6 inhibitors, which block the activity of regulatory enzymes, are tolerated fairly well in patients with cancer; however, oncology nurses should be aware of some strategies that minimize their adverse effects.

Relationship Between Breast Cancer and Posttraumatic Stress Disorder Inconclusive

Relationship Between Breast Cancer and Posttraumatic Stress Disorder Inconclusive

Although a strong correlation between breast cancer diagnosis and stress has been noted — particularly in the form of posttraumatic stress disorder (PTSD) — there is no demonstrable evidence to suggest a direct causal relationship between them.

Counseling Regarding Genetic Testing in Breast Cancer Lacking, Yet Many Still Undergo BLM

Counseling Regarding Genetic Testing in Breast Cancer Lacking, Yet Many Still Undergo BLM

Many women with breast cancer with genetic VUS undergo testing and bilateral mastectomy (BLM) without ever receiving genetic counseling.

Fat Grafting May Lead to Better Outcomes in Postmastectomy Breast Reconstruction

Fat Grafting May Lead to Better Outcomes in Postmastectomy Breast Reconstruction

Fat grafting provides benefits to women with breast cancer considering their options for postmastectomy breast reconstruction, even though this study shows that patient-reported outcomes are similar among women who did and did not undergo the procedure.

Adherence to NCCN Guidelines for Chest CT in Early Stage Breast Cancer Lacking

Adherence to NCCN Guidelines for Chest CT in Early Stage Breast Cancer Lacking

A report on adherence to NCCN Guidelines found that, contrary to guideline recommendations, many asymptomatic patients with stage I/II breast cancer undergo chest CT for pulmonary nodules.

Novel 3D Marker Reduces Radiation, Improves Cosmesis in Breast Conserving Surgery

Novel 3D Marker Reduces Radiation, Improves Cosmesis in Breast Conserving Surgery

Two recent studies examined the benefits of using a 3D bioabsorbable marker to indicate the tumor bed in women with breast cancer who underwent breast conserving surgery (BCS).

Cancer Risks for BRCA1/2 Mutation Carriers Determined by Age, Family History, Mutation Location

Cancer Risks for BRCA1/2 Mutation Carriers Determined by Age, Family History, Mutation Location

Risk assessment study for carriers of the BRCA1/2 mutation identified the factors that influence their risk of developing breast cancer, ovarian cancer, or contralateral breast cancer.

Breast Cancer Overdiagnosis Also a Result of Screening Mammography Programs

Breast Cancer Overdiagnosis Also a Result of Screening Mammography Programs

Screening mammography programs increased early detection of tumors, improving outcomes for those women; however, these programs also increased detection of tumors that would never pose a clinical problem.

Aspirin Use May Lower Breast Cancer Risk in Women with Diabetes

Aspirin Use May Lower Breast Cancer Risk in Women with Diabetes

Regular aspirin use is associated with a lower risk of breast cancer among women with diabetes, a recent study from Taiwan has shown.

Ethnic Differences, Cultural Barriers Negatively Impact Mammography Follow-up Among Asian Ethnic Groups

Ethnic Differences, Cultural Barriers Negatively Impact Mammography Follow-up Among Asian Ethnic Groups

Follow-up after abnormal results on mammography is more likely to be delayed among Asian American women compared with white women, and varies between different Asian ethnicities.

Changes in Pulmonary Function Tests in Breast Carcinoma Patients Treated With Locoregional Post-mastectomy Radiotherapy: Results of a Pilot Study

Changes in Pulmonary Function Tests in Breast Carcinoma Patients Treated With Locoregional Post-mastectomy Radiotherapy: Results of a Pilot Study

[Breast Cancer: Targets and Therapy] The goal of this research was to evaluate the acute changes in PFTs in breast carcinoma patients who received adjuvant chemotherapy and were treated with PMRT including SC regions.

QOL, Adverse Effects Better With Capecitabine After Adjuvant Epirubicin for Breast Cancer

QOL, Adverse Effects Better With Capecitabine After Adjuvant Epirubicin for Breast Cancer

Women with breast cancer who received capecitabine after adjuvant epirubicin had better quality of life (QOL) compared with those who received CMF after adjuvant therapy.

Taxane-based Chemotherapy May Diminish Balance, Gait in Breast Cancer Survivors

Taxane-based Chemotherapy May Diminish Balance, Gait in Breast Cancer Survivors

Breast cancer survivors who received taxane-based chemotherapy for their disease are at increased risk for falls due to CIPN and treatment-associated effects on balance and gait.

Weight-Loss Program Aids African-American Breast Cancer Survivors

Weight-Loss Program Aids African-American Breast Cancer Survivors

Community-based, interventionist-guided weight loss program was efficacious for early-stage survivors.

Adding Pertuzumab to Adjuvant Therapy Is Beneficial for Some Women with Early Breast Cancer

Adding Pertuzumab to Adjuvant Therapy Is Beneficial for Some Women with Early Breast Cancer

Adding a second HER2-blocker to standard care therapy after surgery for HER2-positive breast cancer may be modestly beneficial for some women.

Breast Cancer Diagnosis and Nurse Navigation Survey

Breast Cancer Diagnosis and Nurse Navigation Survey

A patient survey was designed to examine patient views of their initial breast cancer diagnosis process and care management.

Nurse-Led Psychological Intervention Beneficial in Breast Cancer

Nurse-Led Psychological Intervention Beneficial in Breast Cancer

Participants with high risk of depression reported lower mood disturbance, anxiety, depression following intervention.

Ovarian Function Recovery May Increase Risk of Breast Cancer Recurrence

Ovarian Function Recovery May Increase Risk of Breast Cancer Recurrence

Ovarian function recovery (OFR) in women with chemotherapy-induced ovarian function failure decreases residual 5-year disease-free and overall survival.

Novel Approach Increases Breast, Ovarian Cancer Genetic Screening

Novel Approach Increases Breast, Ovarian Cancer Genetic Screening

A questionnaire added to intake forms at a breast cancer imaging center identified women with BRCA mutations who might otherwise have been missed.

Interactive Tool Improves Breast Cancer Treatment Decision-Making

Interactive Tool Improves Breast Cancer Treatment Decision-Making

A tool called iCanDecide prepares patients for making decision about treatment better than static online information, study finds.

Treatment for Breast Cancer in Men Differs From Treatment for Women

Treatment for Breast Cancer in Men Differs From Treatment for Women

Male breast cancer patients are less likely than their female counterparts to receive adjuvant hormone therapy and postlumpectomy radiation.

Efficacy of Trastuzumab Biosimilars Shown Equivalent to Originator in HER2 Breast Cancer

Efficacy of Trastuzumab Biosimilars Shown Equivalent to Originator in HER2 Breast Cancer

Biosimilars and originator trastuzumab neoadjuvant therapy had a comparable effect on pathologic complete response rates.

Cancer Recurrence Fear Reduced by Novel Psychological Intervention

Cancer Recurrence Fear Reduced by Novel Psychological Intervention

'Conquer Fear' decreased fear among survivors of breast and colorectal cancer and melanoma compared with relaxation techniques.

Tai Chi Effective, Affordable Alternative to CBT-I for Insomnia in Breast Cancer Survivors

Tai Chi Effective, Affordable Alternative to CBT-I for Insomnia in Breast Cancer Survivors

Tai chi is as effective as cognitive behavioral therapy for insomnia (CBT-I) for the treatment of insomnia in breast cancer survivors.

Even Small Amounts of Alcohol Can Affect Breast Cancer Risk

Even Small Amounts of Alcohol Can Affect Breast Cancer Risk

Even a small glass of wine each day can increase the odds of both premenopausal and postmenopausal breast cancer, evidence suggests.

Education, Counseling on Caregiving Role for Spouses Improves Outcomes for Women With Breast Cancer

Education, Counseling on Caregiving Role for Spouses Improves Outcomes for Women With Breast Cancer

An educational counseling intervention delivered by nurses directly to spouses of women with breast cancer improved marital communications and patients' appraisal of their spouse's interpersonal support.

Home-based Symptom Management With Caregiver Involvement Improves HRQOL in Advanced Breast Cancer

Home-based Symptom Management With Caregiver Involvement Improves HRQOL in Advanced Breast Cancer

Trends in caregiver involvement in home-based patient care are introducing new avenues for symptom management and improved health-related quality of life for patients undergoing chemotherapy for advanced breast cancer.

Journaling Improves Adherence to Skin Self-Care During Radiation Therapy for Breast Cancer

Journaling Improves Adherence to Skin Self-Care During Radiation Therapy for Breast Cancer

Weekly journaling with oncology nurse review ensures adherence to skin self-care in women undergoing radiation therapy for breast cancer.

Mastectomy vs BCT: Understanding Women's Treatment Choice for Early-Stage Breast Cancer

Mastectomy vs BCT: Understanding Women's Treatment Choice for Early-Stage Breast Cancer

Canadian investigators sought to understand the factors that influence the treatment choices of women with early-stage breast cancer.

High Levels of Negative Emotions in Breast Cancer Survivors Motivates Exercise, Increases Cortisol Levels

High Levels of Negative Emotions in Breast Cancer Survivors Motivates Exercise, Increases Cortisol Levels

Negative emotions were shown to motivate breast cancer survivors to engage in moderate-to-vigorous exercise, and can increase their daytime levels of cortisol.

Position Statement on Fracture Risk With AI Therapy in Early-Stage Breast Cancer Updated

Position Statement on Fracture Risk With AI Therapy in Early-Stage Breast Cancer Updated

Seven interdisciplinary cancer and bone societies released a position statement updating recommendations for limiting bone loss and fracture risk in patients with early-stage breast cancer undergoing treatment with AIs.

Integrating Texture Features in Breast Tissue Analysis Improved Accuracy of Tissue Classification

Integrating Texture Features in Breast Tissue Analysis Improved Accuracy of Tissue Classification

A texture analysis technique improved classification of different types of breast tissue imaged with optical coherence microscopy.

Follow-up Surgery Not Needed When Breast Cancer Responds to Neoadjuvant Chemotherapy

Follow-up Surgery Not Needed When Breast Cancer Responds to Neoadjuvant Chemotherapy

Women with triple-negative or HER2-positive breast cancer who achieve a pathologic complete response from neoadjuvant chemotherapy may be able to avoid follow-up breast or lymph node surgery.

Manipulation Increases Susceptibility of Triple-Negative Breast Cancer to Conventional Therapy

Manipulation Increases Susceptibility of Triple-Negative Breast Cancer to Conventional Therapy

Researchers manipulated triple-negative breast cancer cells to make them susceptible to conventional antiestrogen therapy for breast cancer.

New Criteria for Appropriate Use of Bone Scintigraphy to Diagnose and Manage Prostate and Breast Cancer

New Criteria for Appropriate Use of Bone Scintigraphy to Diagnose and Manage Prostate and Breast Cancer

Several clinical societies came together to create appropriate use criteria for the use of bone scintigraphy in patients with prostate and breast cancer.

Primary Care Physicians Surveyed on Breast Cancer Screening Practices

Primary Care Physicians Surveyed on Breast Cancer Screening Practices

Given recent guideline changes and lack of consistency in guidelines, a survey sought to highlight how primary care physicians recommend breast cancer screening to their patients.

Low Acculturated Latina Women Reported Breast Cancer Treatment Experience Differently Than Other Groups

Low Acculturated Latina Women Reported Breast Cancer Treatment Experience Differently Than Other Groups

Researchers found that low acculturated Latina women were moderately less satisfied with surgeon and oncology communication compared with other racial and ethnic groups.

Cost and Complication Rates Differ Among Early Breast Cancer Treatment Options

Cost and Complication Rates Differ Among Early Breast Cancer Treatment Options

Researchers compared cost data and complications between mastectomy with reconstruction and other guideline-based treatments for patients with early-stage breast cancer.

Use of Counseling, Surgery Rates Show Limited Physician Knowledge of Breast Cancer Genetic Testing

Use of Counseling, Surgery Rates Show Limited Physician Knowledge of Breast Cancer Genetic Testing

Limited use of genetic counselors and high rate of double mastectomy in women at average risk with early-stage breast cancer illustrate that understanding of genetic testing results is limited.

Recommendations Against Contralateral Prophylactic Mastectomy Not Tied to Patient Satisfaction

Recommendations Against Contralateral Prophylactic Mastectomy Not Tied to Patient Satisfaction

Study finds patients are not more likely to report dissatisfaction, seek a second opinion, or change doctors due to physician recommendations against CPM.

Physical Activity Improves Outcomes for Patients with Breast Cancer and Survivors

Physical Activity Improves Outcomes for Patients with Breast Cancer and Survivors

Physical activity is proven to improve both physical and mental effects of cancer diagnosis and treatment, even if the activity needs to be modified to fit the patient's current abilities.

Breast Cancer Rates Increasing in Asian-American Women

Breast Cancer Rates Increasing in Asian-American Women

Out of 7 nationality groups studied, only Japanese women didn't have an overall increase in the disease.

Mastectomy Skin Flap Necrosis: Challenges and Solutions

Mastectomy Skin Flap Necrosis: Challenges and Solutions

[Breast Cancer: Targets and Therapy] This research discusses the management options for incidents of mastectomy skin flap necrosis (MSFN).

Mammograms (Fact Sheet)

Mammograms (Fact Sheet)

This fact sheet reviews the types of mammograms, false-positive and false-negative results, digital mammography, and tomosynthesis mammography.

National Databases Reports on Racial, Socioeconomic Disparities for Breast Reconstruction Vary

National Databases Reports on Racial, Socioeconomic Disparities for Breast Reconstruction Vary

Reporting of overall immediate breast reconstruction and of racial disparities varies significantly between SEER and 2 large US databases.

Contralateral Prophylactic Mastectomies for Early Stage Invasive Breast Cancer Vary by State

Contralateral Prophylactic Mastectomies for Early Stage Invasive Breast Cancer Vary by State

The proportion of women with invasive early-stage unilateral breast cancer electing CPM has increased significantly, and varies across US states.

Benefits of Radiation Therapy Undone by Smoking in Some Breast Cancer Patients

Benefits of Radiation Therapy Undone by Smoking in Some Breast Cancer Patients

Absolute risks from radiation therapy for women with breast cancer who continue to smoke could exceed the absolute benefit of the therapy.

Trends in BRCA Mutation Testing Shifting Toward Unaffected Women

Trends in BRCA Mutation Testing Shifting Toward Unaffected Women

Genetic testing for BRCA gene mutation is increasingly undertaken by women unaffected by breast and/or ovarian cancers.

Postoperative Outcomes Similar With Mobile App Follow-up for Ambulatory Breast Reconstruction

Postoperative Outcomes Similar With Mobile App Follow-up for Ambulatory Breast Reconstruction

Follow-up via mobile app similar to in-person postoperative visits for low-risk ambulatory patients after breast reconstruction.

Risk Calculator Determines Likelihood of PPBCS in Breast Cancer

Risk Calculator Determines Likelihood of PPBCS in Breast Cancer

Risk calculator assesses patients for risk of persistent pain after breast cancer surgery (PPBCS).

Smoking Increases Long-Term Risks From Radiotherapy in Breast Cancer

Smoking Increases Long-Term Risks From Radiotherapy in Breast Cancer

Risk associated with radiotherapy for breast cancer is substantially reduced with smoking cessation.

Genetic Similarity to BRCA1/BRCA2 Mutations May Impact Treatment Options

Genetic Similarity to BRCA1/BRCA2 Mutations May Impact Treatment Options

Genetic signatures similar to BRCA1/BRCA2 mutations could make PARP inhibition a treatment option for some breast cancers.

Evidenced-Based Radiation Treatment Tied to Cost Savings in Early Stage Breast Cancer

Evidenced-Based Radiation Treatment Tied to Cost Savings in Early Stage Breast Cancer

Health care costs lower for early-stage breast cancer when adjuvant radiation therapy follows evidence-based guidelines.

Arm Lymphoscintigraphy After Axillary Lymph Node Dissection or Sentinel Lymph Node Biopsy in Breast Cancer

Arm Lymphoscintigraphy After Axillary Lymph Node Dissection or Sentinel Lymph Node Biopsy in Breast Cancer

[OncoTargets and Therapy] This research examines the lymphatic flow in the arm following breast cancer surgery and axillary lymph node dissection (ALND) versus sentinel lymph node biopsy (SLNB) using lymphoscintigraphy (LS).

Shorter Treatment of Breast Cancer with Trastuzumab May Lead to Improved Results

Shorter Treatment of Breast Cancer with Trastuzumab May Lead to Improved Results

A significantly shorter course of trastuzumab achieved both improved outcomes for patients and cost savings for the UK National Health Service.

Directly Informing Patients of Breast Cancer Risk, Options Improves Follow-Up Screening

Directly Informing Patients of Breast Cancer Risk, Options Improves Follow-Up Screening

Follow-up MRI screening in women at high risk of breast cancer was improved when patients were informed directly of their potential risks and options.

Antiperspirants/Deodorants and Breast Cancer (Fact Sheet)

Antiperspirants/Deodorants and Breast Cancer (Fact Sheet)

This fact sheet examines possible relationships between use of antiperspirants or deodorants and cancer risk.

Immunosuppressor Inhibits Metabolic Pathway in Breast Cancer, Kills Cancer Cells

Immunosuppressor Inhibits Metabolic Pathway in Breast Cancer, Kills Cancer Cells

Leflunomide, an immunosuppressor FDA-approved for rheumatoid arthritis, is effective against breast cancer in mouse study.

Does Pregnancy Increase Risk of Death in Women With Breast Cancer?

Does Pregnancy Increase Risk of Death in Women With Breast Cancer?

Pregnancy around the time of, or after, diagnosis of breast cancer is not associated with an increased risk of death.

Many Breast Cancer Survivors Remain Inactive After Treatment

Many Breast Cancer Survivors Remain Inactive After Treatment

Despite the known benefits of physical activity for breast cancer survivors, a large proportion of this population continues to be physically inactive after treatment.

ASCO Issues Adjuvant Bisphosphonate in Breast Cancer Guideline

ASCO Issues Adjuvant Bisphosphonate in Breast Cancer Guideline

Zoledronic acid and clodranate are the recommended bisphosphonates for the adjuvant treatment of postmenopausal patients with breast cancer.

Skeletal Muscle Mass, Composition Is Predictive of Treatment-Related Toxicity in Breast Cancer

Skeletal Muscle Mass, Composition Is Predictive of Treatment-Related Toxicity in Breast Cancer

Quantity and quality of skeletal muscle is a more accurate measure for determining dose and of potential treatment-related toxicity in patients receiving chemotherapy for early-stage breast cancer.

Trends in Mammography Indicate Better Detection of Cancer, More Biopsies

Trends in Mammography Indicate Better Detection of Cancer, More Biopsies

Digital mammography has improved breast cancer detection, increased biopsies.

Risk of Lung Cancer Increases After Radiation for Breast Cancer

Risk of Lung Cancer Increases After Radiation for Breast Cancer

Treatment with radiation therapy for invasive breast cancer may place East Asian women at a greater risk of developing second primary lung cancer (SPLC).

Docetaxel-associated Myalgia-arthralgia Syndrome in Patients With Breast Cancer

Docetaxel-associated Myalgia-arthralgia Syndrome in Patients With Breast Cancer

[Breast Cancer: Targets and Therapy] This research examines possible risk factors and effectiveness of treatments for docetaxel-associated myalgia-arthralgia syndrome.

Breast Tomosynthesis Technique May Help Reduce Breast Cancer Screening Recall Rate

Breast Tomosynthesis Technique May Help Reduce Breast Cancer Screening Recall Rate

Digital breast tomosynthesis used with full-field digital mammography has the potential to reduce call-back rates for breast examinations.

Supplemental MRI Improves Breast Cancer Detection

Supplemental MRI Improves Breast Cancer Detection

MRI screening has high specificity and positive predictive value in average risk women.

Internet-based Cognitive Behavioral Therapy Beneficial for Improving Sexual Functioning

Internet-based Cognitive Behavioral Therapy Beneficial for Improving Sexual Functioning

Internet-based cognitive behavioral therapy has positive effects on sexual functioning in breast cancer survivors experiencing sexual dysfunction.

Tattoo Transforms Mastectomy Scars Into Personal Art for Breast Cancer Survivors

Tattoo Transforms Mastectomy Scars Into Personal Art for Breast Cancer Survivors

Painter and tattoo artist David Allen has used his skills to transform breasts scarred by surgical reconstruction into works of art.

Patients With a Recurrence Score of 11 to 25 May Not Benefit from Chemo

Patients With a Recurrence Score of 11 to 25 May Not Benefit from Chemo

Patients with hormone receptor-positive, HER2-negative, axillary lymph node-negative breast cancer who have a recurrence score of 11 to 25 may not benefit from chemotherapy.

Patients With HER2-enriched Subtype Benefit Most from Dual HER2 Blockade

Patients With HER2-enriched Subtype Benefit Most from Dual HER2 Blockade

HER-2 enriched subtype predicts for HER2 blockade benefit with lapatinib and trastuzumab

Scalp Cooling Reduces Risk of Chemotherapy-Induced Alopecia

Scalp Cooling Reduces Risk of Chemotherapy-Induced Alopecia

Risk of chemotherapy-induced hair loss common to breast cancer therapy may be reduced with the use of scalp-cooling device.

1 Year of Adjuvant Trastuzumab Improves Long-Term DFS in Early Breast Cancer

1 Year of Adjuvant Trastuzumab Improves Long-Term DFS in Early Breast Cancer

Adjuvant trastuzumab following chemotherapy significantly improves long-term disease-free survival in women with HER2-positive early breast cancer, according to study data.

Myalgia-arthralgia Syndrome Associated With Taxanes in Patients with Breast Cancer

Myalgia-arthralgia Syndrome Associated With Taxanes in Patients with Breast Cancer

[Breast Cancer: Targets and Therapy] This research examines predisposing factors, prevention, and therapy of myalgia-arthralgia syndrome (M-AS).

Women Treated for DCIS Have Slightly Lower Risk for All-Cause Mortality

Women Treated for DCIS Have Slightly Lower Risk for All-Cause Mortality

Risk for all-cause mortality is lower among older women treated for DCIS.

Mammographic Breast Density Correlates With Risk of Primary, Contralateral Breast Cancer

Mammographic Breast Density Correlates With Risk of Primary, Contralateral Breast Cancer

High mammographic breast density is a risk factor for primary breast cancer. In this study, a potential correlation with contralateral breast cancer was investigated.

Cholesterol-Lowering Drugs May Prevent Breast Cancer Recurrence

Cholesterol-Lowering Drugs May Prevent Breast Cancer Recurrence

In this study, the impact of cholesterol-lowering medications on breast cancer recurrence in women receiving adjuvant endocrine therapy was investigated.

Racial Disparities in BRCA-Related Management Strategies

Racial Disparities in BRCA-Related Management Strategies

Fewer black BRCA carriers undergo salpingo-oophorectomy to reduce their risk for breast cancer than their Hispanic and non-Hispanic white counterparts.

False Positive Mammograms More Likely to Delay Subsequent Screening

False Positive Mammograms More Likely to Delay Subsequent Screening

Women who experience a false positive mammogram were more likely to delay their subsequent screening, potentially increasing the risk of having late stage breast cancer at diagnosis.

Some Early Breast Cancer Patients Should Have Breast Conservation Instead of Mastectomy

Some Early Breast Cancer Patients Should Have Breast Conservation Instead of Mastectomy

Investigators from the Netherlands present their research findings on survival in women with early stage breast cancer who underwent breast-conserving therapy vs mastectomy at the 2017 European Cancer Congress.

Might a Chemical from Celery and Broccoli One Day Yield a New Drug to Prevent Breast Cancer Metastasis?

Might a Chemical from Celery and Broccoli One Day Yield a New Drug to Prevent Breast Cancer Metastasis?

Investigators report on their findings from preclinical studies of luteolin injections to prevent lung metastases of triple-negative breast cancer.

Inflammatory Cytokine Levels Increase Breast Tissue Density, Cancer Risk

Inflammatory Cytokine Levels Increase Breast Tissue Density, Cancer Risk

Discovered link between inflammation and overexpression of CCL2 hints at potential of anti-inflammatory medications as a breast cancer preventive in women with dense-tissue breasts.

Soy Consumption Influences Tamoxifen Efficacy Against Breast Tumor Recurrence

Soy Consumption Influences Tamoxifen Efficacy Against Breast Tumor Recurrence

Lifelong soy consumption improves tamoxifen response in women with breast cancer; however, adding soy to diet after initiating tamoxifen therapy may not provide the same benefits.

Gastric and Colon Metastasis From Breast Cancer: Case Report, Review of the Literature, and Possible Underlying Mechanisms

Gastric and Colon Metastasis From Breast Cancer: Case Report, Review of the Literature, and Possible Underlying Mechanisms

[Breast Cancer: Targets and Therapy] This research presents a case report of patient with gastrointestinal metastases from breast cancer.

Underuse, Misuse of Adjuvant Endocrine Therapy for Breast Cancer Has Decreased

Underuse, Misuse of Adjuvant Endocrine Therapy for Breast Cancer Has Decreased

Although significant variation in care persists, underuse and misuse of adjuvant endocrine therapy for breast cancer has decreased since 2004.

Neoadjuvant Chemotherapy May Benefit African-American Women with Breast Cancer

Neoadjuvant Chemotherapy May Benefit African-American Women with Breast Cancer

Administering chemotherapy to African-American women with breast cancer prior to surgery may help improve their survival.

A Call for Better Efforts to Treat and Prevent Breast Cancer Treatment-Related Toxicities

A Call for Better Efforts to Treat and Prevent Breast Cancer Treatment-Related Toxicities

Researchers report that clinicians may want to start collecting toxicity data routinely and offering early interventions to patients with breast cancer.

Letrozole Not Superior to Anastrazole for HR+, Node+ Early Breast Cancer

Letrozole Not Superior to Anastrazole for HR+, Node+ Early Breast Cancer

Letrozole was not superior to anastrazole with respect to efficacy or safety in postmenopausal women with HR-positive, node-positive early breast cancer.

Zoledronic Acid Every 12 Weeks Noninferior to Every 4 Weeks

Zoledronic Acid Every 12 Weeks Noninferior to Every 4 Weeks

Researchers sought to determine the noninferiority of continuing zoledronic acid for an additional year every 12 weeks vs zoledronic acid every 4 weeks in patients receiving monthly intravenous zoledronic acid and/or pamidronate disodium for 1 year or longer.

New Understanding of Mechanisms Revealed in Development of Breast Cancer and Resistance to Treatment

New Understanding of Mechanisms Revealed in Development of Breast Cancer and Resistance to Treatment

Researchers explore the biologic influences of breast cancer development and resistance to treatment.

Women With Early-Stage Breast Cancer Report Substantial Treatment-Related Toxicities

Women With Early-Stage Breast Cancer Report Substantial Treatment-Related Toxicities

In this study, researchers quantified the frequency, severity, and burden of treatment-associated toxicities in patients with early-stage invasive breast cancer using patient surveys.

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