Risk Calculator Determines Likelihood of PPBCS in Breast Cancer

Risk Calculator Determines Likelihood of PPBCS in Breast Cancer

Risk calculator assesses patients for risk of persistent pain after breast cancer surgery (PPBCS).

Smoking Increases Long-Term Risks From Radiotherapy in Breast Cancer

Smoking Increases Long-Term Risks From Radiotherapy in Breast Cancer

Risk associated with radiotherapy for breast cancer is substantially reduced with smoking cessation.

Genetic Similarity to BRCA1/BRCA2 Mutations May Impact Treatment Options

Genetic Similarity to BRCA1/BRCA2 Mutations May Impact Treatment Options

Genetic signatures similar to BRCA1/BRCA2 mutations could make PARP inhibition a treatment option for some breast cancers.

Evidenced-Based Radiation Treatment Tied to Cost Savings in Early Stage Breast Cancer

Evidenced-Based Radiation Treatment Tied to Cost Savings in Early Stage Breast Cancer

Health care costs lower for early-stage breast cancer when adjuvant radiation therapy follows evidence-based guidelines.

Arm Lymphoscintigraphy After Axillary Lymph Node Dissection or Sentinel Lymph Node Biopsy in Breast Cancer

Arm Lymphoscintigraphy After Axillary Lymph Node Dissection or Sentinel Lymph Node Biopsy in Breast Cancer

[OncoTargets and Therapy] This research examines the lymphatic flow in the arm following breast cancer surgery and axillary lymph node dissection (ALND) versus sentinel lymph node biopsy (SLNB) using lymphoscintigraphy (LS).

Shorter Treatment of Breast Cancer with Trastuzumab May Lead to Improved Results

Shorter Treatment of Breast Cancer with Trastuzumab May Lead to Improved Results

A significantly shorter course of trastuzumab achieved both improved outcomes for patients and cost savings for the UK National Health Service.

Directly Informing Patients of Breast Cancer Risk, Options Improves Follow-Up Screening

Directly Informing Patients of Breast Cancer Risk, Options Improves Follow-Up Screening

Follow-up MRI screening in women at high risk of breast cancer was improved when patients were informed directly of their potential risks and options.

Antiperspirants/Deodorants and Breast Cancer (Fact Sheet)

Antiperspirants/Deodorants and Breast Cancer (Fact Sheet)

This fact sheet examines possible relationships between use of antiperspirants or deodorants and cancer risk.

Immunosuppressor Inhibits Metabolic Pathway in Breast Cancer, Kills Cancer Cells

Immunosuppressor Inhibits Metabolic Pathway in Breast Cancer, Kills Cancer Cells

Leflunomide, an immunosuppressor FDA-approved for rheumatoid arthritis, is effective against breast cancer in mouse study.

Does Pregnancy Increase Risk of Death in Women With Breast Cancer?

Does Pregnancy Increase Risk of Death in Women With Breast Cancer?

Pregnancy around the time of, or after, diagnosis of breast cancer is not associated with an increased risk of death.

Many Breast Cancer Survivors Remain Inactive After Treatment

Many Breast Cancer Survivors Remain Inactive After Treatment

Despite the known benefits of physical activity for breast cancer survivors, a large proportion of this population continues to be physically inactive after treatment.

ASCO Issues Adjuvant Bisphosphonate in Breast Cancer Guideline

ASCO Issues Adjuvant Bisphosphonate in Breast Cancer Guideline

Zoledronic acid and clodranate are the recommended bisphosphonates for the adjuvant treatment of postmenopausal patients with breast cancer.

Skeletal Muscle Mass, Composition Is Predictive of Treatment-Related Toxicity in Breast Cancer

Skeletal Muscle Mass, Composition Is Predictive of Treatment-Related Toxicity in Breast Cancer

Quantity and quality of skeletal muscle is a more accurate measure for determining dose and of potential treatment-related toxicity in patients receiving chemotherapy for early-stage breast cancer.

Trends in Mammography Indicate Better Detection of Cancer, More Biopsies

Trends in Mammography Indicate Better Detection of Cancer, More Biopsies

Digital mammography has improved breast cancer detection, increased biopsies.

Risk of Lung Cancer Increases After Radiation for Breast Cancer

Risk of Lung Cancer Increases After Radiation for Breast Cancer

Treatment with radiation therapy for invasive breast cancer may place East Asian women at a greater risk of developing second primary lung cancer (SPLC).

Docetaxel-associated Myalgia-arthralgia Syndrome in Patients With Breast Cancer

Docetaxel-associated Myalgia-arthralgia Syndrome in Patients With Breast Cancer

[Breast Cancer: Targets and Therapy] This research examines possible risk factors and effectiveness of treatments for docetaxel-associated myalgia-arthralgia syndrome.

Breast Tomosynthesis Technique May Help Reduce Breast Cancer Screening Recall Rate

Breast Tomosynthesis Technique May Help Reduce Breast Cancer Screening Recall Rate

Digital breast tomosynthesis used with full-field digital mammography has the potential to reduce call-back rates for breast examinations.

Supplemental MRI Improves Breast Cancer Detection

Supplemental MRI Improves Breast Cancer Detection

MRI screening has high specificity and positive predictive value in average risk women.

Internet-based Cognitive Behavioral Therapy Beneficial for Improving Sexual Functioning

Internet-based Cognitive Behavioral Therapy Beneficial for Improving Sexual Functioning

Internet-based cognitive behavioral therapy has positive effects on sexual functioning in breast cancer survivors experiencing sexual dysfunction.

Tattoo Transforms Mastectomy Scars Into Personal Art for Breast Cancer Survivors

Tattoo Transforms Mastectomy Scars Into Personal Art for Breast Cancer Survivors

Painter and tattoo artist David Allen has used his skills to transform breasts scarred by surgical reconstruction into works of art.

Patients With a Recurrence Score of 11 to 25 May Not Benefit from Chemo

Patients With a Recurrence Score of 11 to 25 May Not Benefit from Chemo

Patients with hormone receptor-positive, HER2-negative, axillary lymph node-negative breast cancer who have a recurrence score of 11 to 25 may not benefit from chemotherapy.

Patients With HER2-enriched Subtype Benefit Most from Dual HER2 Blockade

Patients With HER2-enriched Subtype Benefit Most from Dual HER2 Blockade

HER-2 enriched subtype predicts for HER2 blockade benefit with lapatinib and trastuzumab

Scalp Cooling Reduces Risk of Chemotherapy-Induced Alopecia

Scalp Cooling Reduces Risk of Chemotherapy-Induced Alopecia

Risk of chemotherapy-induced hair loss common to breast cancer therapy may be reduced with the use of scalp-cooling device.

1 Year of Adjuvant Trastuzumab Improves Long-Term DFS in Early Breast Cancer

1 Year of Adjuvant Trastuzumab Improves Long-Term DFS in Early Breast Cancer

Adjuvant trastuzumab following chemotherapy significantly improves long-term disease-free survival in women with HER2-positive early breast cancer, according to study data.

Myalgia-arthralgia Syndrome Associated With Taxanes in Patients with Breast Cancer

Myalgia-arthralgia Syndrome Associated With Taxanes in Patients with Breast Cancer

[Breast Cancer: Targets and Therapy] This research examines predisposing factors, prevention, and therapy of myalgia-arthralgia syndrome (M-AS).

Women Treated for DCIS Have Slightly Lower Risk for All-Cause Mortality

Women Treated for DCIS Have Slightly Lower Risk for All-Cause Mortality

Risk for all-cause mortality is lower among older women treated for DCIS.

Mammographic Breast Density Correlates With Risk of Primary, Contralateral Breast Cancer

Mammographic Breast Density Correlates With Risk of Primary, Contralateral Breast Cancer

High mammographic breast density is a risk factor for primary breast cancer. In this study, a potential correlation with contralateral breast cancer was investigated.

Cholesterol-Lowering Drugs May Prevent Breast Cancer Recurrence

Cholesterol-Lowering Drugs May Prevent Breast Cancer Recurrence

In this study, the impact of cholesterol-lowering medications on breast cancer recurrence in women receiving adjuvant endocrine therapy was investigated.

Racial Disparities in BRCA-Related Management Strategies

Racial Disparities in BRCA-Related Management Strategies

Fewer black BRCA carriers undergo salpingo-oophorectomy to reduce their risk for breast cancer than their Hispanic and non-Hispanic white counterparts.

False Positive Mammograms More Likely to Delay Subsequent Screening

False Positive Mammograms More Likely to Delay Subsequent Screening

Women who experience a false positive mammogram were more likely to delay their subsequent screening, potentially increasing the risk of having late stage breast cancer at diagnosis.

Some Early Breast Cancer Patients Should Have Breast Conservation Instead of Mastectomy

Some Early Breast Cancer Patients Should Have Breast Conservation Instead of Mastectomy

Investigators from the Netherlands present their research findings on survival in women with early stage breast cancer who underwent breast-conserving therapy vs mastectomy at the 2017 European Cancer Congress.

Might a Chemical from Celery and Broccoli One Day Yield a New Drug to Prevent Breast Cancer Metastasis?

Might a Chemical from Celery and Broccoli One Day Yield a New Drug to Prevent Breast Cancer Metastasis?

Investigators report on their findings from preclinical studies of luteolin injections to prevent lung metastases of triple-negative breast cancer.

Inflammatory Cytokine Levels Increase Breast Tissue Density, Cancer Risk

Inflammatory Cytokine Levels Increase Breast Tissue Density, Cancer Risk

Discovered link between inflammation and overexpression of CCL2 hints at potential of anti-inflammatory medications as a breast cancer preventive in women with dense-tissue breasts.

Soy Consumption Influences Tamoxifen Efficacy Against Breast Tumor Recurrence

Soy Consumption Influences Tamoxifen Efficacy Against Breast Tumor Recurrence

Lifelong soy consumption improves tamoxifen response in women with breast cancer; however, adding soy to diet after initiating tamoxifen therapy may not provide the same benefits.

Gastric and Colon Metastasis From Breast Cancer: Case Report, Review of the Literature, and Possible Underlying Mechanisms

Gastric and Colon Metastasis From Breast Cancer: Case Report, Review of the Literature, and Possible Underlying Mechanisms

[Breast Cancer: Targets and Therapy] This research presents a case report of patient with gastrointestinal metastases from breast cancer.

Underuse, Misuse of Adjuvant Endocrine Therapy for Breast Cancer Has Decreased

Underuse, Misuse of Adjuvant Endocrine Therapy for Breast Cancer Has Decreased

Although significant variation in care persists, underuse and misuse of adjuvant endocrine therapy for breast cancer has decreased since 2004.

Neoadjuvant Chemotherapy May Benefit African-American Women with Breast Cancer

Neoadjuvant Chemotherapy May Benefit African-American Women with Breast Cancer

Administering chemotherapy to African-American women with breast cancer prior to surgery may help improve their survival.

A Call for Better Efforts to Treat and Prevent Breast Cancer Treatment-Related Toxicities

A Call for Better Efforts to Treat and Prevent Breast Cancer Treatment-Related Toxicities

Researchers report that clinicians may want to start collecting toxicity data routinely and offering early interventions to patients with breast cancer.

Letrozole Not Superior to Anastrazole for HR+, Node+ Early Breast Cancer

Letrozole Not Superior to Anastrazole for HR+, Node+ Early Breast Cancer

Letrozole was not superior to anastrazole with respect to efficacy or safety in postmenopausal women with HR-positive, node-positive early breast cancer.

Zoledronic Acid Every 12 Weeks Noninferior to Every 4 Weeks

Zoledronic Acid Every 12 Weeks Noninferior to Every 4 Weeks

Researchers sought to determine the noninferiority of continuing zoledronic acid for an additional year every 12 weeks vs zoledronic acid every 4 weeks in patients receiving monthly intravenous zoledronic acid and/or pamidronate disodium for 1 year or longer.

New Understanding of Mechanisms Revealed in Development of Breast Cancer and Resistance to Treatment

New Understanding of Mechanisms Revealed in Development of Breast Cancer and Resistance to Treatment

Researchers explore the biologic influences of breast cancer development and resistance to treatment.

Women With Early-Stage Breast Cancer Report Substantial Treatment-Related Toxicities

Women With Early-Stage Breast Cancer Report Substantial Treatment-Related Toxicities

In this study, researchers quantified the frequency, severity, and burden of treatment-associated toxicities in patients with early-stage invasive breast cancer using patient surveys.

New Use of an Old Drug Could Address Cancer Metastasis

New Use of an Old Drug Could Address Cancer Metastasis

CDK 4/6 inhibitors, currently approved for the treatment of estrogen-positive breast cancer, were found to inhibit metastasis in triple-negative breast

Intervention Reduces Fear of Recurrence for Breast Cancer Survivors

Intervention Reduces Fear of Recurrence for Breast Cancer Survivors

The Attention and Interpretation Modification for Fear of Breast Cancer Recurrence (AIM-FBCR) intervention helped reduce health worries for survivors of breast cancer.

The Affordable Care Act Has Increased the Use of Mammography But Not Colonoscopy

The Affordable Care Act Has Increased the Use of Mammography But Not Colonoscopy

An assessment of the use of mammography and colonoscopy among fee-for-service Medicare beneficiaries before and after the Affordable Care Act demonstrates the impact of out-of-pocket costs in this population.

Screening for Breast Cancer Correlates with Significant Overdiagnosis

Screening for Breast Cancer Correlates with Significant Overdiagnosis

A review of data from 2 Danish cancer registries revealed the incidence of overdiagnosis of tumors not likely to affect a patient's health during her lifetime and diagnosis of advanced tumors in a program offering biennial mammography for women aged 50 to 69 years.

Menopause-specific QoL Changes Associated With Chemoprevention Nonadherence

Menopause-specific QoL Changes Associated With Chemoprevention Nonadherence

A cohort of participants in the MAP.3 trial completed the MENQOL questionnaire, and the findings shed light on the influence of changes in menopause-specific quality of life on aromatase inhibitor adherence in women at high risk for breast cancer.

Perceived Breast Density May Influence Single Read Suitability

Perceived Breast Density May Influence Single Read Suitability

Features mainly linked to mammographic breast density are key in influencing a classification of normal.

Longer Dosing Interval of Zoledronic Acid May Be Acceptable for Bone Metastases

Longer Dosing Interval of Zoledronic Acid May Be Acceptable for Bone Metastases

Results from a phase 3 trial comparing a 12-week dosing interval with the standard 4-week dosing interval of zoledronic acid to reduce the incidence of skeletal-related events and pain in patients with bone metastases.

Serum IL-12 May Predict for Chemotherapy-Related Fatigue in Early-Stage Breast Cancer

Serum IL-12 May Predict for Chemotherapy-Related Fatigue in Early-Stage Breast Cancer

In this study, researchers sought to identify physical, neurocognitive, and serologic markers that may correlate with self-reported fatigue before and after (neo)adjuvant chemotherapy for patients with early-stage breast cancer.

Patients With Breast Cancer Report More Cognitive Difficulties After Chemotherapy

Patients With Breast Cancer Report More Cognitive Difficulties After Chemotherapy

Researchers sought to evaluate the incidence of cancer-related cognitive impairment in patients with breast cancer in a large prospective, longitudinal, nationwide study. These findings address limitations in previous research.

Drug-Drug Interaction Between Capecitabine and PPIs Reduces Survival in GI Cancers

Drug-Drug Interaction Between Capecitabine and PPIs Reduces Survival in GI Cancers

Drug-drug interaction between capecitabine and common heartburn medications has a negative effect on progression-free survival and overall survival in patients with GI cancer.

Breast Cancer Follow-Up Care Recommendations: Considerations for a Growing Survivorship Population

Breast Cancer Follow-Up Care Recommendations: Considerations for a Growing Survivorship Population

Women with a history of breast cancer face a wide variety of challenges as they transition from the role of "patient" to "survivor".

Biomarker Predicts Anthracycline-caused Heart Damage in Women with Breast Cancer

Biomarker Predicts Anthracycline-caused Heart Damage in Women with Breast Cancer

Investigators have identified a genetic biomarker that can help determine congestive heart failure risk in individuals undergoing chemotherapy for breast cancer.

BRCA Testing, Not Mastectomies, Show Increase After Jolie Editorial

BRCA Testing, Not Mastectomies, Show Increase After Jolie Editorial

More women tested for the BRCA genes but no corresponding increase in mastectomy rates

Peer Navigation Program Helpful for Patients With Hereditary Cancers

Peer Navigation Program Helpful for Patients With Hereditary Cancers

Participants in a peer navigation program for patients at risk for HBOC were surveyed regarding the usefulness of the information provided, patient education, and their peer navigator. Survey results were presented at the 2016 SABCS.

MOCHA App Facilitates Communication Between Caregivers, Patients

MOCHA App Facilitates Communication Between Caregivers, Patients

An app developed to track posthospitalization progress and activity of patients with breast cancer, adding the information into patients' electronic health records in real time, was presented at SABCS 2016.

Social Isolation Can Adversely Affect Breast Cancer Survival

Social Isolation Can Adversely Affect Breast Cancer Survival

Weak social ties are associated with poorer survival and a higher risk of breast cancer recurrence, researchers say.

Scalp-cooling Device To Reduce Chemotherapy-related Alopecia

Scalp-cooling Device To Reduce Chemotherapy-related Alopecia

A new system appears efficacious in preventing chemotherapy-related alopecia in women with breast cancer, according to a study presented at SABCS 2016.

Menopause-related Nausea/Vomiting and Headaches Effects Tamoxifen Adherence

Menopause-related Nausea/Vomiting and Headaches Effects Tamoxifen Adherence

Women who experienced menopause-related side effects were significantly less likely to adhere to their assigned tamoxifen therapy.

Community Breast Navigation Program Improved Breast Screening Rates in Underserved African American and Latino Women

Community Breast Navigation Program Improved Breast Screening Rates in Underserved African American and Latino Women

A community breast navigation program successfully increased mammogram screening rates among African American and Latino women, according to a study presented at the 2016 San Antonio Breast Cancer Symposium (SABCS).

Live-streamed Videos Address End-of-Life Planning, Decision-making

Live-streamed Videos Address End-of-Life Planning, Decision-making

Live-streamed videos are a novel and forward-thinking approach for individuals to learn about end-of-life (EOL) planning and decision-making, according a study presented at the 2016 San Antonio Breast Cancer Symposium.

Metastatic Disease Linked to Patients Reporting Diminished QoL

Metastatic Disease Linked to Patients Reporting Diminished QoL

Patients with metastatic breast cancer have significantly diminished quality of life (QoL) compared with those without metastatic disease and those without breast cancer, a study presented at the 2016 San Antonio Breast Cancer Symposium.

History of Bilateral Salpingo-oophorectomy, Hormone Replacement Therapy Are Predictive of Breast Density at Cancer Diagnosis

History of Bilateral Salpingo-oophorectomy, Hormone Replacement Therapy Are Predictive of Breast Density at Cancer Diagnosis

A history of surgical menopause and were receiving hormone replacement therapy are a factor in breast density, according to a study presented at the 2016 San Antonio Breast Cancer Symposium (SABCS).

Mammographically Occult Contralateral Breast Cancer Detection is Effective With Preoperative MRI

Mammographically Occult Contralateral Breast Cancer Detection is Effective With Preoperative MRI

Study data presented at SABCS 2016 indicates that preoperative MRI is effective for detecting mammographically occult, early-stage, hormone receptor (HR)-positive contralateral breast cancer (CBC) in older patients.

Clinical Breast Examination Superior to MRI for Predicting pCR in HER2+ Breast Cancer

Clinical Breast Examination Superior to MRI for Predicting pCR in HER2+ Breast Cancer

Clinical breast examination (CBE) is superior to MRI for predicting pathologic complete response (pCR) in women with HER2-positive breast cancer, a study presented at the 2016 San Antonio Breast Cancer Symposium indicates.

Video Tool to Increase Breast Cancer Clinical Trial Participation Among Black Women

Video Tool to Increase Breast Cancer Clinical Trial Participation Among Black Women

A new tool may show promise for improving clinical trial participation among black women with breast cancer, according to a study presented at the 2016 San Antonio Breast Cancer Symposium (SABCS).

Genomic Features Predictive of Response to Trastuzumab-Containing Therapy

Genomic Features Predictive of Response to Trastuzumab-Containing Therapy

Research presented at SABCS 2016 identified biomarkers predictive of response to trastuzumab-containing therapies in patients with HER2-positive breast cancer.

No Difference Between RA Seed Localization and Wire Guided Localization

No Difference Between RA Seed Localization and Wire Guided Localization

Results of a comparison study of radioactive seed localization and wire guided localization in patients with nonpalpable invasive breast cancer or DCIS were presented at SABCS 2016.

BRD4 Inhibitor May Enhance Sensitivity to Endocrine Therapies

BRD4 Inhibitor May Enhance Sensitivity to Endocrine Therapies

A novel bromodomain-containing protein 4 inhibitor demonstrated antitumor activity in both endocrine-sensitive and endocrine-resistance breast cancer models, according to a study presented at SABCS 2016.

Dual HER2 Blockade With an AI Effective in Advanced Breast Cancer

Dual HER2 Blockade With an AI Effective in Advanced Breast Cancer

Patients with HER2-positive, HR-positive advanced breast cancer experience significantly improved progression-free survival when pertuzumab is added to first-line trastuzumab and an AI compared with trastuzumab and an AI alone, according to study findings presented at SABCS 2016.

Loperamide Regimen May Reduce Diarrhea in Neratinib-treated Patients

Loperamide Regimen May Reduce Diarrhea in Neratinib-treated Patients

Investigators report on the efficacy of a structured prophylactic regimen of loperamide for 2 cycles to reduce incidence and severity of neratinib-associated diarrhea in patients with HER2-positive early-stage breast cancer, at SABCS 2016.

PAM50 HER2-E Subtype Predicts pCR Following Lapatinib, Trastuzumab

PAM50 HER2-E Subtype Predicts pCR Following Lapatinib, Trastuzumab

In this presentation at SABCS 2016, researchers present an evaluation of the ability of the PAM50 HER2-enriched intrinsic subtype to predict pathologic complete response in the breast in patients who received 18 weeks of neoadjuvant dual HER2 blockade.

Arsenic Pretreatment May Protect Normal Tissue During Chemo in Breast Cancer

Arsenic Pretreatment May Protect Normal Tissue During Chemo in Breast Cancer

Researchers found that temporary pretreatment with LDA may protect normal breast tissue during chemotherapy for breast cancer in patients undergoing breast-conserving therapy, according to a study presented at SABCS 2016.

Netupitant/Palonosetron Efficacious for Prevention of N/V in Patients Receiving MEC or HEC

Netupitant/Palonosetron Efficacious for Prevention of N/V in Patients Receiving MEC or HEC

In a poster presentation at SABCS 2016, researchers reported on the efficacy and safety of netupitant/palonosetron (NEPA) for the prevention of CINV in patients receiving highly or moderately emetogenic chemotherapy.

Costs, Complications Higher for Women Who Undergo Second Surgery After BCS

Costs, Complications Higher for Women Who Undergo Second Surgery After BCS

A study presented at SABCS 2016 reports on the incidence of complications and costs in women who undergo breast-conserving surgery for breast carcinoma.

Omitting RT in Certain Older Women With Early Breast Cancer is Safe

Omitting RT in Certain Older Women With Early Breast Cancer is Safe

Researchers report their study findings on the safety of omitting radiotherapy after breast-conserving surgery, sentinel node biopsy, and adjuvant endocrine therapy in older patients with early breast cancer and favorable histopathology at SABCS 2016.

Fluorescent Nanoparticles Represent Novel Detection Method of HER2 Expression

Fluorescent Nanoparticles Represent Novel Detection Method of HER2 Expression

Researchers investigated the potential of PID fluorescent nanoparticles, a novel detection technique to visualize and quantify protein in clinical samples, for quantifying HER2 protein expression in breast cancer, according to a study presented at SABCS 2016.

Assessment of Stromal Features in DCIS Requires Robustness

Assessment of Stromal Features in DCIS Requires Robustness

Robustness of dichotomous assessment is important when evaluating stromal features of ductal carcinoma in situ (DCIS), according to a study presented at SABCS 2016.

RANKL Inhibition May Represent Promising Breast Cancer Prevention Strategy

RANKL Inhibition May Represent Promising Breast Cancer Prevention Strategy

Research presented at 2016 SABCS showed whether RANKL inhibition could reduce the risk for developing breast cancer in BRCA1 mutation carriers.

Bi-allelic Inactivation Common in BRCA1 and BRCA Breast Cancers

Bi-allelic Inactivation Common in BRCA1 and BRCA Breast Cancers

Bi-allelic inactivation of BRCA1 and BRCA2 are frequent events in BRCA1 breast cancers and BRCA2 breast cancers, respectively, according to a study presented at SABCS 2016.

In HER2+ Breast Cancer, Higher TIL Levels Associated With Improved OS

In HER2+ Breast Cancer, Higher TIL Levels Associated With Improved OS

In this study presented at SABCS 2016, investigators determined the association between higher TIL levels and overall survival in patients with advanced HER2-positive breast cancer treated with docetaxel plus trastuzumab in combination with pertuzumab or placebo.

High Immune Gene Expression Linked to Better Prognosis in TNBC

High Immune Gene Expression Linked to Better Prognosis in TNBC

Researchers assessed the relationship between immune gene expression and genomic complexity in TNBC in a study presented at SABCS 2016.

Extended Treatment With Letrozole Fails to Improve DFS in HR+ Breast Cancer

Extended Treatment With Letrozole Fails to Improve DFS in HR+ Breast Cancer

Today at SABCS 2016 investigators presented results of the NRG Oncology/NSABP B-42, a double-blind phase 3 trial to determine whether extended treatment with letrozole would improve disease-free survival in certain women with HR-positive breast cancer.

Study Identifies Patients Who May Derive More Benefit From Veliparib

Study Identifies Patients Who May Derive More Benefit From Veliparib

At SABCS 2016, researchers presented study findings demonstrating whether neoadjuvant treatment, PARPi-7, BRCAness, and MP1/2 predict response to veliparib plus carboplatin therapy in patients with high-risk breast cancer.

Latina Breast Cancer Survivors Experience Gaps in Survivorship Care

Latina Breast Cancer Survivors Experience Gaps in Survivorship Care

A study using focus groups identifies barriers that impact the quality of survivorship care for Latina women with breast cancer.

Biosimilar Promising for Treatment of ERBB2+ Breast Cancer

Biosimilar Promising for Treatment of ERBB2+ Breast Cancer

Equivalent response rate for women with ERBB2-positive metastatic breast cancer receiving taxanes

Acupuncture Improves Postoperative Symptoms in Women Undergoing Surgery for Breast Cancer

Acupuncture Improves Postoperative Symptoms in Women Undergoing Surgery for Breast Cancer

The effects of a 2-treatment course of acupuncture on pain, nausea, and anxiety and ability to cope among women undergoing mastectomy was compared with usual care.

Perindopril, Bisoprolol Not Effective for Preventing Trastuzumab-mediated Left Ventricular Remodeling

Perindopril, Bisoprolol Not Effective for Preventing Trastuzumab-mediated Left Ventricular Remodeling

Perindopril, an angiotensin-converting enzyme (ACE) inhibitor, and the beta blocker bisoprolol protected against trastuzumab-related declines.

Resistance Training Improves Posttreatment Outcomes for Breast Cancer Survivors

Resistance Training Improves Posttreatment Outcomes for Breast Cancer Survivors

Loss of bone density related to chemotherapy and adjuvant therapy for breast cancer can lead to debilitating hip and vertebral fractures. This discussion discusses the impact of resistance training for these patients.

Depression May Contribute to Receipt of Inappropriate Breast Cancer Treatment

Depression May Contribute to Receipt of Inappropriate Breast Cancer Treatment

An analysis of data from Danish women with early-stage breast cancer assessed women's risk of receiving nonguideline treatment for their disease if they had a prior diagnosis of depression or prior treatment with antidepressants.

Vaginal Ring/Cream May Be Feasible for Urogenital Atrophy

Vaginal Ring/Cream May Be Feasible for Urogenital Atrophy

The feasibility of an estradiol-releasing vaginal ring vs intravaginal testosterone cream for women with HR-positive stage I to III breast cancer using aromatase inhibitors who reported vaginal dryness, decreased libido, or dyspareunia is evaluated in a phase 2 study.

Hospital Volume Linked to Odds of Appropriate Breast Cancer Locoregional Treatment

Hospital Volume Linked to Odds of Appropriate Breast Cancer Locoregional Treatment

Investigators examined the extent to which hospital volume explains variations in diagnosis and treatment of breast cancer.

Higher Protein Intake May Modestly Improve Breast Cancer Survival

Higher Protein Intake May Modestly Improve Breast Cancer Survival

An analysis of data from women with stage I to III breast cancer investigated the potential association between protein intake and survival.

Economic Burden Related to Chemotherapy-related Adverse Events in Patients with Metastatic Breast Cancer in an Integrated Health Care System

Economic Burden Related to Chemotherapy-related Adverse Events in Patients with Metastatic Breast Cancer in an Integrated Health Care System

[Breast Cancer: Targets and Therapy] This research evaluates costs related to chemotherapy-related adverse events in patients with metastatic breast cancer in an integrated health care delivery system.

Telerehabilitation Program Improves Posttreatment Effects in Breast Cancer Survivors

Telerehabilitation Program Improves Posttreatment Effects in Breast Cancer Survivors

Study evaluates whether a web-based rehabilitation program can effectively improve pain, fatigue, strength, and quality of life for breast cancer survivors.

Both Older and Younger Women Benefit From Breast Reconstruction

Both Older and Younger Women Benefit From Breast Reconstruction

No greater risk of complications for older patients; benefited as much as younger breast cancer patients

Prolactin Expression May Indicate Better Prognosis for Patients With TNBC

Prolactin Expression May Indicate Better Prognosis for Patients With TNBC

Expression of this hormone receptor may indicate a less aggressive subtype of triple-negative breast cancer and better prognosis for patients with the disease.

Adherence to Tamoxifen, AIs Among Older Women is Low, Study Shows

Adherence to Tamoxifen, AIs Among Older Women is Low, Study Shows

A data analysis reveals the likelihood of older women with to ER-positive DCIS to initiate and adhere to adjuvant tamoxifen or aromatase inhibitors.

Nonadherence to Posttreatment Imaging Follow-up Common Among Breast Cancer Survivors

Nonadherence to Posttreatment Imaging Follow-up Common Among Breast Cancer Survivors

In this study, researchers assessed data on women who underwent breast cancer treatment to identify the factors associated with posttreatment imaging use.

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