Genes linked to breast cancer in East Asian women identified

A new study has identified three genetic changes in East Asian women linked to an increased risk of breast cancer.

Rethinking Breast Cancer Screening: Ultra FAST Breast MRI [EDITORIALS]

Rethinking Breast Cancer Screening: Ultra FAST Breast MRI [EDITORIALS]

Breast cancer screening is once again controversial. In this editorial, the author discusses new research demonstrating the effectiveness of an MRI imaging technique called first postcontrast subtracted T1-weighted image (FAST).

Standard of care for delivering bisphophonates

Standard of care for delivering bisphophonates

What is the preferred delivery protocol for breast cancer adjuvant bisphosphonates?

Genetics is the dominant risk factor for familial breast, prostate, and colorectal cancers

A study of people who were adopted identified genetics as the dominant risk factor in familial breast, prostate, and colorectal cancers.

No change seen in breast cancer detection despite increased Medicare costs for screening

Breast cancer screening costs for Medicare patients skyrocketed between 2001 and 2009, but the increase did not lead to earlier detection of new breast cancer cases, according to a study.

Hormones after breast cancer: natural steroid hormones may be safe, effective

Hormones after breast cancer: natural steroid hormones may be safe, effective

A new study suggests a safe and effective role for natural steroid hormones in treating postmenopausal breast cancer, with fewer detrimental side effects and improved health profile than with standard antihormone therapies.

New blood test predicts risk of nonhereditary breast cancer

New blood test predicts risk of nonhereditary breast cancer

A simple blood test is currently in development that could help predict the likelihood of a woman developing breast cancer, even in the absence of a high-risk BRCA1 gene mutation, according to new research.

Gene marker may help predict breast cancer response to tamoxifen

Gene marker may help predict breast cancer response to tamoxifen

Researchers have identified genes that may help predict whether a patient with estrogen receptor (ER)-positive breast cancer is likely to benefit from tamoxifen therapy, according to a study.

Genetic profile and potential drug susceptibility of breast cancer cells revealed by CTCs

Circulating tumor cells captured with a microchip-based device can be cultured to establish cell lines for genetic analysis and drug testing.

Parabens in Cosmetics: What Is the Connection to Cancer?

Parabens in Cosmetics: What Is the Connection to Cancer?

Current studies indicate that the levels of parabens used in cosmetics are safe (typical levels are 0.1% to 0.3%); however, many believe a relationship to cancer exists, particularly breast cancer. The furor came about after a 2004 study reported finding parabens in the breast tissue of 20 women.

Update of staging criteria for breast cancer diagnosis recommended

New findings paint a relatively optimistic picture of women's chances of surviving a subset of breast cancers that have spread to the chest wall or skin, but not beyond.

Scientists bring personalized medicine for breast cancer one step closer

Scientists bring personalized medicine for breast cancer one step closer

The era of personalized medicine for breast cancer may be just around the corner, thanks to recent advances by USC Stem Cell researcher Min Yu and scientists at Massachusetts General Hospital and Harvard Medical School.

Cultured circulating tumor cells reveal genetic profile of breast cancer cells

Cultured circulating tumor cells reveal genetic profile of breast cancer cells

Researchers have created a microchip device that can capture circulating tumor cells, in order to track ongoing genetic mutation within a tumor.

Protein pushes breast cancer cells to metastasize

Using an innovative tool that captures heretofore hidden ways that cells are regulated, scientists have identified a protein that makes breast cancer cells more likely to metastasize.

Breast cancer screening costs on the rise for Medicare patients

Breast cancer screening costs on the rise for Medicare patients

Although use of newer technologies and costs associated with breast cancer screening have increased, no change in stage at diagnosis has been observed in Medicare beneficiaries.

Skin gel helps fight against breast cancer

Skin gel helps fight against breast cancer

A gel containing the drug tamoxifen and applied to the skin was as effective as the pill form in reducing the growth of breast cancer cells in women with noninvasive cancer.

Mammography has led to fewer late-stage breast cancers

In the 30 years since mammography was introduced, late-stage breast cancer incidence has decreased by 37%, according to a new study. The analysis, from the University of Michigan Comprehensive Cancer Center in Ann Arbor, takes into account an observed underlying trend of increased breast cancer incidence present since the 1940s

Latest findings give optimistic picture of breast cancer survival odds

Latest findings give optimistic picture of breast cancer survival odds

New findings from Fox Chase Cancer Center paint a relatively optimistic picture of women's chances of surviving a subset of breast cancers that have spread to the chest wall or skin.

CTCs can be captured and cultured for genetic analysis and drug testing of breast cancer cells

CTCs can be captured and cultured for genetic analysis and drug testing of breast cancer cells

A microchip-based device developed at the Massachusetts General Hospital (MGH) Center for Engineering in Medicine and the MGH Cancer Center can capture circulating tumor cells (CTCs). The CTCs can then be cultured to establish cell lines for genetic analysis and drug testing.

Inhibitor of cholesterol biosynthesis may have potential as breast cancer treatment

A compound initially developed as a treatment for high cholesterol not only halts the progression of breast cancer, but also can kill cancer cells.

ESC: Hyperlipidemia increases breast cancer risk

ESC: Hyperlipidemia increases breast cancer risk

The presence of hyperlipidemia has been linked to 1.64-fold increased risk of breast cancer.

Barriers to obtaining gene expression profiling tests increase their perceived value among patients

Barriers to obtaining gene expression profiling tests increased their perceived importance among patients with early breast cancer (estrogen-receptor positive [ER+], human epidermal growth-factor receptor 2 negative [HER2-], and node negative) who were deciding whether to have chemotherapy after surgery, according to a new study from Canada.

Researchers suggest updating the staging criteria for breast cancer diagnoses

Researchers suggest updating the staging criteria for breast cancer diagnoses

Study findings from Fox Chase Cancer Center offer relatively optimistic news for women with breast cancer whose disease has spread to the chest wall or skin, but not beyond.

IUDs may up breast cancer risk

IUDs may up breast cancer risk

A new study has found that the levonorgestrel-releasing intrauterine system, or progesterone-releasing IUD, may be associated with a higher than expected incidence of breast cancer.

Telephone call is effective support when breast cancer treatment includes weight loss

A series of simple telephone calls can make a profound difference in helping women with breast cancer to meet their treatment goals for weight loss.

HER2 testing may incorrectly classify some women with breast cancer

A recent study of HER2 testing in a large cohort of women with breast cancer found important limitations in testing methods.

New markers for breast cancer may assist diagnoses

New markers for breast cancer may assist diagnoses

The fight against breast cancer is never-ending, but Virginia Tech researchers have found additional diagnostic markers that may aid clinicians to better forecast and prevent the disease.

High sugar intake may increase breast cancer risk

High sugar intake may increase breast cancer risk

The more sugary drinks a woman consumes, the greater her risk for breast cancer, a study has found.

State law requires advising women of dense breast tissue, breast cancer risk

State law requires advising women of dense breast tissue, breast cancer risk

Massachusetts legislators introduced a bill that requires doctors to tell patients when a mammogram reveals that the woman has breast dense tissue.

Combination imaging helps breast tumor differentiation

Combination imaging helps breast tumor differentiation

The use of new technique, which includes four approaches, could reduce unnecessary breast biopsies.

Cholesterol levels may be tied to breast cancer risk

Cholesterol levels may be tied to breast cancer risk

High cholesterol levels may increase a woman's risk of developing breast cancer, a large new British study reports.

Does frailty influence the use of adjuvant hormone treatment in older breast cancer patients?

Does frailty influence the use of adjuvant hormone treatment in older breast cancer patients?

Many patients older than 65 years with localized breast cancer are eligible for adjuvant hormonal therapy, but little is known about why patients start and stop treatment.

Benefits of trastuzumab outweigh the risk of harm in advanced breast cancer

A new systematic review shows that treatment with the breast cancer drug trastuzumab is associated with prolonged survival in women with advanced breast cancer, but the risk of developing heart problems also increases.

Screening mammography costs soar for seniors

Screening mammography costs soar for seniors

In a comparison of data from 2001-2002 and 2008-2009, the use of screening mammography for Medicare-enrolled women without a history of breast cancer was consistent, at approximately 42%. However, the increase in use of more expensive digital mammography technology has resulted in higher costs ($115 vs $73 per mammogram).

Bisphenol A Triggers Changes in Rats That May Lead to Breast Cancer

Bisphenol A Triggers Changes in Rats That May Lead to Breast Cancer

New research presents another cause for concern in regard to the chemical bisphenol A (BPA). The study is the first to examine what impact BPA has on the DNA of mammary glands as they age.

Breast cancer detection hasn't increased in line with costs

Breast cancer detection hasn't increased in line with costs

Medicare's mammography costs increased by almost 50% over a 7-year period while the breast cancer detection rate and stage at diagnosis did not change, according to a study.

Racial disparities in breast cancer care extends to lymph node biopsy

Racial disparities in breast cancer care extends to lymph node biopsy

A study from the University of Texas MD Anderson Cancer Center reveals a disparity in use of sentinel lymph node biopsy between black and white women.

Combination imaging can distinguish malignant and benign breast tumors

Combination imaging can distinguish malignant and benign breast tumors

Imaging breast tumors using four approaches together can better distinguish between malignant breast tumors and those that are benign, compared with imaging using fewer approaches.

Drug resistance reversed when tamoxifen is paired with antimalarial agent

The antimalarial drug hydroxychloroquine (HCQ) reverses resistance to tamoxifen in mice, according to investigators.

Leukemia gene leads to potential target for triple-negative breast cancer treatment

Leukemia gene leads to potential target for triple-negative breast cancer treatment

Scientists have discovered that a gene previously linked to leukaemia could provide an urgently needed target for the development of drugs to treat patients with 'triple negative' breast cancer.

Digital mammography with tomosynthesis lowers recalls

Digital mammography with tomosynthesis lowers recalls

Compared with digital mammography alone, the combination of digital mammography and tomosynthesis increases cancer detection and reduces false-positive results, according to research.

A career change to radiation oncology nursing

A career change to radiation oncology nursing

What is the best approach to learning more about the field of Radiation Oncology?

Mammography has reduced numbers of late-stage breast cancers

Since mammography was introduced late-stage breast cancer incidence has decreased by 37%, according to a new study

African-American women more likely to be diagnosed with higher-risk breast cancer

African-American women frequently present with biologically less favorable subtypes of breast cancer, according to a research study.

Breast cancer gene needs protein partner to grow

Breast cancer gene needs protein partner to grow

A study has revealed that the gene Metadherin—which is implicated in promoting the spread of breast cancer tumors—only stimulates tumor growth when the protein made by the gene interacts with a second protein.

Molecular imaging visualizes novel way to knock down breast cancer

A recent innovation in breast cancer biomarkers seeks to visualize the HER3 receptor, which could mean more comprehensive breast cancer imaging and potential treatments.

Lymphedema awareness low in patients with breast cancer

Lymphedema awareness low in patients with breast cancer

Although they experienced classic symptoms of post-surgical lymphedema, many breast patients didn't recognize the condition as related to treatment.

Molecular breast imaging protocol unmasks more cancer in advanced cases

Patients with advanced breast cancer that may have spread to their lymph nodes could benefit from a more robust dose of a molecular imaging agent when undergoing lymphoscintigraphy.

Preoperative genetic testing steers surgical choice in breast cancer

Preoperative genetic testing steers surgical choice in breast cancer

Majority of BRCA mutation carriers opted for different surgery than initially planned by surgeon.

Limiting carbs may reduce breast cancer recurrence in some women

Limiting carbs may reduce breast cancer recurrence in some women

Reducing carbohydrate intake could reduce the risk of breast cancer recurrence among women whose tumor tissue is positive for the insulin-like growth factor-1 (IGF1) receptor, according to a new study.

BPA stimulates breast cancer cells growth

BPA stimulates breast cancer cells growth

A chemical commonly used in plastics, appears to increase the proliferation of breast cancer cells, according to Duke Medicine researchers.

Phone intervention helps women with breast cancer lose weight

Phone intervention helps women with breast cancer lose weight

Among postmenopausal women receiving letrozole as adjuvant therapy for breast cancer, a telephone-based weight loss intervention was effective in promoting weight loss.

Diet may impact breast cancer recurrence

Diet may impact breast cancer recurrence

Personalized dietary recommendations based on molecular characteristics of primary tumor tissue may be an effective strategy for breast cancer survivors, according to research.

Benefits of trastuzumab outweigh risk of harm for advanced breast cancer

In women with advanced (or metastatic) breast cancer, treatment with the breast cancer drug trastuzumab is associated with prolonged survival but also increases the risk of developing heart problems

Annual MRI and digital mammography effective for screening high-risk women

Annual MRI and digital mammography effective for screening high-risk women

Initial results indicate that annual magnetic resonance imaging (MRI) and digital mammography can form an effective screening program for women at high risk of breast cancer, according to research.

New test predicts if breast cancer will spread

New test predicts if breast cancer will spread

A test of tumor microenvironment of metastasis (TMEM) predicted risk of distant metastasis in estrogen receptor-positive and HER2-negative breast cancer, according to a new study.

Mammograms may significantly decrease breast cancer mortality

Mammograms may significantly decrease breast cancer mortality

In the latest major study to consider whether the dangers of mammograms outweigh the benefits, experts say the tests can reduce the chances of dying from breast cancer by nearly 30 percent.

Educational video reduces barriers to early detection of breast cancer

Educational video reduces barriers to early detection of breast cancer

A documentary film showcasing the stories of local women who survived breast cancer may help educate African American women in breast cancer risks and early treatment.

Aromatherapy reduces anxiety during breast biopsy

Aromatherapy reduces anxiety during breast biopsy

A study evaluating the effectiveness of aromatherapy as a complementary/alternative modality for reducing anxiety in women undergoing CNB was presented at the Oncology Nursing Society 39th Annual Congress.

Workshop prepares nurses to address sexual concerns of breast cancer survivors

Workshop prepares nurses to address sexual concerns of breast cancer survivors

Sexual health workshops increased nurse knowledge and confidence, allowing nurses to address sexual concerns of breast cancer survivors.

Four genes confirmed as increasing familial breast cancer risk

Four new genes have been added to the growing list of those known to cause increased breast cancer risk when mutated.

Breast cancer surgery trends in Canada similar to that in United States

Breast cancer surgery trends in Canada similar to that in United States

To better understand breast cancer surgery trends in Canada, researchers reviewed data from the Canadian Institute for Health (CHI) on 57,840 women who underwent breast cancer surgery between 2007 and 2010.

Gene mutation lowers breast cancer survival

Gene mutation lowers breast cancer survival

Women with a specific gene mutation have a higher risk of dying from a type of breast cancer, according to a study that raised prospects of targeted drugs.

Breast MRI discovering other suspect masses

Breast MRI discovering other suspect masses

When women undergo MRIs to check for breast cancer, the scans sometimes reveal suspicious masses elsewhere in the body, which can generate a lot of anxiety and require more testing.

Patient risk information improves mammogram interpretation

Patient risk information improves mammogram interpretation

A research group's findings demonstrate a role for risk profiling in the interpretation of mammograms. The new approach takes into account a woman's health risk profile, which may reduce both the number of missed cancers and false positives.

Breast cancer risk linked to higher red meat intake

Breast cancer risk linked to higher red meat intake

Risk could be reduced by substitution of other legumes or poultry for red meat.

Late-stage breast cancer less frequent in mammography era

Late-stage breast cancer less frequent in mammography era

There appears to have been a decrease in late-stage breast cancer in the mammography era, according to a study published online.

Lowering carb intake could help reduce breast cancer risk

Lowering carb intake could help reduce breast cancer risk

Concerned about the associations between obesity, diabetes, and cancer risk, researchers examined the links between carbohydrate intake and breast cancer risk.

Most older patients use hormone therapy to treat their breast cancer

Most older patients use hormone therapy to treat their breast cancer

Except for frail patients, most participants in a large study complied with their oncologists' recommendations to treat their estrogen-positive breast cancer with hormone therapy.

Study Shows Older Patients With Breast Cancer Patients Do Follow Drug Therapy

Study Shows Older Patients With Breast Cancer Patients Do Follow Drug Therapy

Many older breast cancer patients with localized disease are taking drug treatments to prevent their cancer from returning, a new study finds. The research, covering a 7-year period, included more than 1,000 women, age 65 to 91 years, across the United States who had estrogen-positive breast cancer that had not spread.

Few women meet exercise guidelines after breast cancer diagnosis

Few women meet exercise guidelines after breast cancer diagnosis

Only 35 percent of women meet current physical activity guidelines after breast cancer diagnosis, with African-American women less likely to meet guidelines, according to a study published online.

Moles may indicate greater breast cancer risk

Moles may indicate greater breast cancer risk

In two studies, a higher risk of breast cancer seen for women with more moles.

Treating breast cancer drug resistance via a malaria drug

Treating breast cancer drug resistance via a malaria drug

An inexpensive malaria drug could be the answer for some women who are not responding to their cancer treatment, according to a promising but preliminary animal study.

Building a great support system for patients with breast cancer

Building a great support system for patients with breast cancer

The driving forces in the evolution of health care are the aging US population, an increasing cultural awareness of health and cancer, and recognition of patients as consumers.

MRI catches breast cancer early in at-risk survivors of childhood Hodgkin lymphoma

The largest clinical study to evaluate breast cancer screening of female survivors of childhood Hodgkin lymphoma, showed that MRI detected invasive breast tumors at very early stages, when cure rates are expected to be excellent.

Patient-centered educational and behavioral program reduces risk of lymphedema

Promoting lymph flow and optimizing BMI after breast cancer surgery had a 97% success rate for patients in the program 1 year after surgery, according to a new study.

Patients with breast cancer underuse needle biopsy

Patients with breast cancer underuse needle biopsy

Needle biopsy appears to be underused in patients with breast cancer, according to a study published online June 9 in the Journal of Clinical Oncology.

Yoga decreases Inflammation and fatigue in patients with breast cancer

Yoga decreases Inflammation and fatigue in patients with breast cancer

Three months of yoga practice is enough to reduce inflammation and fatigue in breast cancer survivors, a study has found.

Book Offers Information for Women about Breast Cancer

Book Offers Information for Women about Breast Cancer

Although most women are aware of breast cancer and know someone who has battled the disease, hearing the words "You have cancer" can be a traumatic experience. They can be easily overwhelmed by the information presented during a consult with their doctor. This new book can help them manage their cancer care.

Exercise halves breast cancer risk

Exercise halves breast cancer risk

Using combination of exercise and diet to lose weight can significantly cut the risk of breast cancer.

Invasive recurrence risk explored for HER2 breast cancer

Invasive recurrence risk explored for HER2+ breast cancer

For patients with HER2+ breast cancer, distant invasive recurrence is low for T1a tumors and is higher for T1b tumors.

Scientists at Scripps Florida find new targets that could increase effectiveness and reduce side effects in breast cancer treatments

Scientists at Scripps Florida find new targets that could increase effectiveness and reduce side effects in breast cancer treatments

Scientists from the Florida campus of The Scripps Research Institute have found new targets for potential intervention in breast cancer.

Post-chemo cognitive depreciation linked to brain activity changes

Post-chemo cognitive depreciation linked to brain activity changes

For patients undergoing chemotherapy for breast cancer, cognitive complaints after treatment may be associated with changes in brain activity, according to a study.

Prophylactic double mastectomy following breast cancer diagnosis often not needed

Prophylactic double mastectomy following breast cancer diagnosis often not needed

Approximately 70% of women who have both breasts removed following a breast cancer diagnosis do so despite a very low risk of facing cancer in the healthy breast, new research has found.

pCR Not a surrogate for relapse-free survival in TNBC BRCA1/2 mutation carriers

pCR Not a surrogate for relapse-free survival in TNBC BRCA1/2 mutation carriers

In patients with triple-negative breast cancer (TNBC) who are BRCA1/2 mutation carriers, pathologic complete response (pCR) is not a surrogate for relapse-free survival, in contrast to those with non-BRCA mutations.

Drinking tea can reduce risk of breast cancer

Drinking tea can reduce risk of breast cancer

Tea drinkers could have less of a breast cancer risk as it increases the functions of blood vessels, says a new research.

Exposure to solvents may increase breast cancer risk

Exposure to solvents may increase breast cancer risk

Occupational exposure to solvents before first full-term birth may be associated with an increased risk of breast cancer in certain settings, according to a study.

Powerful new way to treat HER2-positive breast cancer validated

Powerful new way to treat HER2-positive breast cancer validated

HER2-positive breast cancer typically develops resistance to Herceptin within several years. researchers have found a means of inhibiting another protein whose expression is also upregulated in HER2-positive breast cancer.

ASCO: Goserelin helps preserve ovarian function in early breast cancer

ASCO: Goserelin helps preserve ovarian function in early breast cancer

For premenopausal women with hormone receptor-negative early breast cancer treated with chemotherapy, goserelin can preserve ovarian function, according to a study presented at the annual ASCO meeting.

Large panel genetic testing in breast cancer produces more questions than answers

Although large genetic testing panels promise to uncover clues about patients' DNA, a team of researchers has found that those powerful tests tend to produce more questions than they answer.

Research shows potential targeted therapy for metastatic breast cancer

Research shows potential targeted therapy for metastatic breast cancer

Results from an open label clinical study evaluating the drug enobosarm shows promise for women with metastatic, androgen receptor positive, estrogen receptor positive breast cancer.

Survivors of childhood Hodgkin lymphoma should be screened for breast cancer

Survivors of childhood Hodgkin lymphoma should be screened for breast cancer

Women that suffered from childhood Hodgkin lymphoma should seek magnetic resonance imaging (MRI) screening for early breast cancer detection.

Adding lapatinib to adjuvant trastuzumab not beneficial in early-stage HER2+ breast cancer

Adding lapatinib to adjuvant trastuzumab not beneficial in early-stage HER2+ breast cancer

Adding lapatinib to adjuvant trastuzumab for early-stage HER2-positive breast cancer does not improve patients' disease-free survival rates.

Exemestane + ovarian function suppression reduces recurrence risk in HR-positive early breast cancer

Exemestane + ovarian function suppression reduces recurrence risk in HR-positive early breast cancer

Adjuvant treatment with the aromatase inhibitor (AI) exemestane plus ovarian function suppression significantly reduced risk of disease recurrence in premenopausal women with hormone receptor (HR)-positive early breast cancer compared with tamoxifen plus ovarian function suppression (OFS), representing "a new treatment option for premenopausal women."

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