A new blood test for peptides cleaved by carboxypeptidase N may soon be available to help detect early stages of breast cancer.
McMaster University researchers found no difference in patients with breast cancer who used simple compression bandages to treat lymphedema compared with those who underwent daily lymphatic massage.
As cholesterol is metabolized, a potent stimulant of breast cancer is created—one that fuels estrogen receptor (ER)-positive breast cancers, according to new research.
Software that recognizes patterns in data is commonly used by scientists and economists. Now, researchers in the United States have applied similar algorithms to help them more accurately diagnose breast cancer.
A screening mammography interval of less than 1.5 years is associated with a significantly reduced rate of lymph node positivity.
Use of digital breast tomosynthesis (DBT) demonstrated reduced callback rates and improved cancer detection when compared with mammography.
Mammographic density is associated with breast cancer among women younger than 50 years, according to a study.
A type of mutation that develops after breast cancer patients take antiestrogen therapies has been identified. These mutations help to explain why patients often become resistant to these types of therapies.
Women from BRCA2 families without mutation still have higher breast cancer risk.
More than 500,000 women in the United States have a breast biopsy each year. Percutaneous biopsies are associated with fewer complications than the surgical approach, but short-term side effects such as pain and emotional distress are still significant.
Giving trastuzumab and anthracyclines concurrently is not necessary to achieve a high rate of complete pathologic remission in HER2-positive breast cancer. The results of a recent phase III clinical trial show that administering the treatments sequentially is equally effective.
Mutations in the genes that defend the body against cancer-related viruses and other infections may play a larger role in breast cancer than previously thought.
A large national study has found that the rate of women undergoing magnetic resonance imaging (MRI) of the breast nearly tripled from 2005 to 2009: from four to 11 examinations per 1,000 women.
Testing Morbidities Index scores are down by about three points for each decade decrease in the patient's age.
Two studies show increases in MRI use; few meet criteria of American Cancer Society for screening.
Breast conservation less frequently performed for males with breast cancer, according to research.
Although a breast cancer diagnosis is usually an extremely stressful experience for most women, a new study has found that there also can be unexpected benefits.
Persistent postmastectomy pain is rated by survivors as the most troubling symptom by women with breast cancer who undergo surgery.
Among patients with early stages of breast cancer, the risk of heart disease is higher for those whose hearts were more directly irradiated with radiation treatments on the left side in a facing-up position.
Two studies show promising results in invasive ductal carcinoma and early breast cancer.
Patient assistance programs can help breast cancer patients meet a variety of needs. When these needs are unmet, they can interfere with getting recommended adjuvant therapies such as radiation, chemotherapy, and hormonal treatments.
Breast cancer cell growth, motility, and aggression is promoted by excess glucose, as experienced by patients with diabetes and metabolic syndrome, reports a new study.
Can the drug paroxetine mesylate (Brisdelle, Paxil) be given to patients taking a chemoprevention drug such as raloxifene (Evista) or any of the aromatase inhibitors?
An investigational new PARP inhibitor, BMN 673, is showing early responses in patients with heavily pretreated, advanced, BRCA-related cancers of the breast and ovary.
A small-molecule inhibitor of CDK 4/6 being developed showed promising results in drug-resistant melanoma and drug-resistant breast cancer when tested in combination with other targeted therapies.
A survey finds that most patients are not being told about the possibility of overdiagnosis and overtreatment as a result of cancer screenings.
Women with the faulty genes BRCA1 and BRCA2 have abnormal levels of female hormones in the bloodstream, which leads them to develop breast and ovarian cancer rather than other cancers, according to new research.
Increasingly, women with early-stage breast cancer opt for an aggressive operation to remove both breasts, known as contralateral prophylactic mastectomy, but research findings suggest that having a healthy breast removed may not provide a survival benefit.
An optical imaging technique that measures metabolic activity in cancer cells can accurately differentiate breast cancer subtypes, and can detect responses to treatment as early as 2 days after therapy administration.
This fact sheet defines adjuvant therapy for breast cancer and explains the length of treatment, which patients are best suited for this treatment, side effects, and highlights current research.
The addition of circulating hormone levels correlates with improved breast cancer risk prediction, according to a study.
Significant linear trends between travel distance to cancer center with cancer stage, and type of surgery.
Highest cardiac radiation doses and excess risks are from left-sided treatment in the supine position, researchers found.
A genetic predisposition to cancer is not the same as having cancer. Support for patients with the BRCA gene mutation should meet these unique needs.
Biomarkers have been identified that vary with breast cancer progression, and short telomere length associated with increased risk of aggressive prostate cancer.
Findings from a study involving thousands of postmenopausal women suggest that women who develop invasive breast cancer may benefit from taking supplements that contain both multivitamins and minerals.
This fact sheet reviews breast cancer risk factors for women, including SEER report information and age-related disparities.
This fact sheet reviews this rare form of breast cancer, including symptoms, prognosis, and treatment details.
This fact sheet reviews common sites of cancer metastasis, methods of spread, treatment, and additional details.
Risk the same as found in women in the general population with regard to oral contraceptive use.
All persons with invasive breast cancer (early stage or recurrence) should undergo testing for human epidermal growth factor receptor 2 (HER2), and at least one tumor sample should be tested for either HER2 protein expression or HER2 gene amplification.
Giving radiation therapy to the lymph nodes located behind the breast bone and above the collar bone to patients with early breast cancer improves overall survival without increasing side effects.
Sentinel lymph node surgery was associated with a false-negative rate higher than a prespecified threshold in women who underwent chemotherapy after initially presenting with biopsy-proven breast cancer in movable axillary lymph nodes.
Significant reductions seen in local and metastatic recurrence, and breast cancer-related mortality, when paravertebral block combined with general anesthesia is employed.
Researchers have estimated the daily dose of radiation therapy that is wasted in compensating for cancer cell growth that occurs overnight and during weekends in patients with early breast cancer, which could shorten radiation therapy schedules.
This fact sheet reviews mammograms, including the benefits and risks of mammography and screening recommendations.
This fact sheet reviews bone cancer, including its possible causes, frequency, symptoms, diagnosis, and treatment.
This fact sheet defines hormones and reviews aspects of hormone therapy for breast cancer.
New findings that run counter to federal recommendations indicate that women should be encouraged to initiate regular mammographic screening before age 50 years.
Researchers have not only confirmed that tamoxifen induces cognitive dysfunction in users, they have also found an existing treatment that can prevent this adverse effect.
Women of Mexican descent who had more children and breastfed were more likely to develop an aggressive breast cancer, according to results from the Ella Binational Breast Cancer Study.
Researchers have uncovered a decreased risk of breast cancer among women who walk 7 or more hours per week compared with women who walk for 3 hours or less per week.
Breast cancer incidence rates increased in African American women from 2006 to 2010 and are now approaching the rates found in white women, according to a new analysis by ACS researchers.
No consistent correlation between fluorescence and pathological sentinel lymph node metastasis has been found.
Many older women with newly diagnosed breast cancer have difficulty accomplishing daily tasks, and African Americans seem to be disproportionately affected.
Removal of all axillary lymph nodes may be unnecessary in women undergoing breast-conserving therapy (partial mastectomy followed by whole-breast radiation), researchers have found.
Updated guidelines recommend determining HER2 status for all with invasive breast cancer.
Many women with breast cancer overestimate their risk for developing the disease in the unaffected breast and undergo contralateral prophylactic mastectomy (CPM) despite knowing that this procedure does not clearly improve survival.
As little as an hour a day of walking reduces breast cancer risk among postmenopausal women.
In women with ductal carcinoma in situ (DCIS), breast-conserving treatment combined with radiotherapy reduces the risk for local recurrence (LR), a recent study indicates.
Patients with early-stage breast cancer who receive external beam therapy are not at higher risk for serious long-term side effects in the chest area.
The FDA approved Perjeta (pertuzumab) for the neoadjuvant treatment of breast cancer, first generic version of Xeloda (capecitabine) has gained FDA approval, and other FDA actions.
A biomarker based on the expression levels of seven tumor-specific genes was able to accurately assess the risk for breast cancer recurrence beyond the first 5 years of treatment.
With increase, incidence rates are converging for white and African-American women in U.S.
Perjeta is first FDA-approved drug for neoadjuvant treatment of breast cancer
A website has been developed to help navigate the new challenges posed by breast-density notification laws, according to a recent special report.
The impact of hormone replacement therapy (HRT) use on breast cancer risk varies according to patient race/ethnicity, body mass index (BMI), and breast density, researchers have learned.
Most deaths from breast cancer occur in younger women who do not receive regular mammograms, according to a new study. The study indicates that regular screening before age 50 years should be encouraged.
Appropriately dosed hypofractionated radiotherapy is safe and effective for patients with early breast cancer, according to 10-year follow-up data from two randomized controlled trials.
Clinicians should discuss medications for breast cancer that can help women at increased risk for the disease, but such medications should not be used by women who are not at increased risk.
Increased stem cell self-renewal and subsequent mammary stem cell enrichment are the culprits of breast cancer that develops later among women who were exposed to ionizing radiation as young women, according to a new study.
Tamoxifen, raloxifene recommended for women with raised risk, low risk of adverse medication effects.
More likely among African-American women with newly diagnosed non-metastatic breast cancer
A review of calcium and vitamin D supplementation trials revealed that current recommended doses are inadequate to prevent bone mineral density loss in women undergoing breast cancer therapy.
MEK1/2 inhibition rescues glial progenitor cells from toxicity; prevents tamoxifen-induced cell death.
Long-term follow-up of the START trials confirms that hypofractionated radiotherapy is safe and effective for the treatment of invasive early breast cancer.
Rapid increase in mammography screening program increases clinical cancer care volumes and time until treatment.
The breast cancer index (BCI) was the only one of three methods compared that predicted the risk for recurrence in women treated for estrogen-receptor (ER)-positive breast cancer.
Findings in spite of knowing contralateral prophylactic mastectomy doesn't improve survival.
A generic version of the oral chemotherapy drug Xeloda (capecitabine) has been approved by the U.S. Food and Drug Administration to treat cancers of the colon/rectum or breast.
Multiple bilateral (MB) circumscribed breast masses detected with ultrasound screening are almost always benign, according to research.
When ductal carcinoma in situ (DCIS, a preinvasive malignancy of the breast) is described as a high-risk condition rather than cancer, more women report that they would opt for nonsurgical treatments.
CR systems are 21 percent less effective at detecting breast cancers than screen-film mammography, but digital direct radiography is found to have similar cancer detection rates.
Some metastasizing breast cancer cells express genes that make them more likely to prosper in bone tissue, according to new research.
The luminal breast cancer subtype has enhanced expression of the ERBB3 oncogene, and depleting the ERBB3 protein with an antibody promotes cancer cell death and decreases tumor growth in vitro, according to a new study.
A protein that may help predict breast cancer prognosis has been identified, with the potential to relieve thousands of women at low risk from having to undergo painful, often debilitating, therapies.
More than 70 percent of breast cancer deaths occur among unscreened women.
Survival up for patients with early breast cancer, especially for hormone-receptor positive tumors, after treatment with response-guided neoadjuvant chemotherapy.
Breast lesions categorized as probably benign on supplemental ultrasound screening could be re-evaluated via imaging in 12 months, according to a multisite imaging trial.
HRT-linked risk up for white, Asian, Hispanic women; for low/normal BMI and dense breasts.
Women with breast cancer felt less depressed after creating personal websites that allowed them to chronicle their cancer experiences online and stay in touch with their social networks.
Adding to the picture of what prompts breast cancer to form, researchers have found that distant estrogen response elements can act independently of oncogenes to spur tumor development.
Study examined short- to mid-term duration of insulin use, and the results were unaffected by insulin dosage, duration of use, and tumor stage.
Triple-negative breast cancers may be vulnerable to drugs that attack the proteasome. The proteasome is the cellular structure that disposes the waste of the cell by breaking down damaged or unneeded proteins
Drinking alcohol between menarche and first pregnancy is associated with an increased risk of breast cancer and proliferative benign breast disease (BBD).
ATF3 expression in stromal mononuclear cells correlates with clinical outcomes and predicts death.
Despite taking a tailored risk assessment that factored in family history and personal habits, nearly 20% of women did not believe their breast cancer risk, according to a new study.
Heavy use of magnetic resonance imaging (MRI) may be leading to unnecessary breast removal in older women with breast cancer, according to a new study.
Cellular therapy and gene therapy have been successfully combined in a mouse model to develop a viable treatment strategy for breast cancer that has spread to a patient's brain.
Combining tomosynthesis with digital mammography lowered recall rates by 30% among women being screened for breast cancer, with the greatest reductions seen in patients younger than age 50 years and in those with dense breasts.
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