Brain Metastasis

Survival Is Better With SRS Than With WBRT for NSCLC or Breast Cancer Metastases to the Brain

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Longer survival was achieved with stereotactic radiosurgery (SRS) alone than with whole-brain radiation therapy (WBRT) in patients with fewer than 4 brain metastases from NSCLC or breast cancer.

Ceritinib Benefits Patients with ALK-positive NSCLC and Brain Metastases

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In patients previously treated with crizotinib for ALK-positive NSCLC and brain metastases, ceritinib treatment elicited clinically meaningful whole-body and intracranial responses with an acceptable tolerability profile.

First-line Afatinib Benefits Lung Cancer Patients With Brain Metastases

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For patients with non-small cell lung cancer who have EGFR mutations and brain metastases, progression-free survival was improved with afatinib compared to chemotherapy.

Radiosurgery and Careful Monitoring Combo Recommended for Newly Diagnosed Brain Metastases

Radiosurgery and Careful Monitoring Combo Recommended for Newly Diagnosed Brain Metastases

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Radiosurgery and close monitoring is recommended to better preserve cognitive function in newly diagnosed brain metastases.

Single therapy offers improved survival in younger patients with limited brain metastases

Single therapy offers improved survival in younger patients with limited brain metastases

Data clearly demonstrated stereotactic radiosurgery (SRS) alone offered benefits for younger patients with limited metastases.

Brain mets: Time for a new approach

Brain mets: Time for a new approach

A blue-ribbon team of national experts stated that professional pessimism and out-of-date myths rather than current science may compromise the care of patients with brain cancer.

Molecular imaging tracer improves accuracy of treatment plans for brain metastases

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Imaging with a molecular imaging tracer can help distinguish radiation-induced lesions from new tumor growth in patients who have been treated with radiation for brain metastases, according to new research.

Interleukin-2 extends life in melanoma brain metastases

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Researchers are suggesting that high-dose interleukin-2 (HD IL-2) therapy should be considered as a treatment option in patients with melanoma brain metastases who are otherwise eligible for therapy, based on the encouraging results of a small retrospective review.

Brain chemotherapy improves survival after lung metastasis

Intraventricular chemotherapy to the brain improved symptoms and survival in persons with leptomeningeal carcinomatosis following lung cancer.

Proteins mark metastasizing breast cancer cells

Researchers have identified a novel signature of circulating tumor cells (CTCs) from breast cancer that metastasize to the brain.

Triple-drug regimen controls brain metastasis in breast cancer

Combining trastuzumab and lapatinib with an anti-VEGFR2 antibody dramatically improved survival in HER2 breast cancer with brain metastases.

A clearer role for radiotherapy in high-risk melanoma

A clearer role for radiotherapy in high-risk melanoma

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A new study suggests radiotherapy may hold clinical promise for the control of local lymph node bed recurrence of malignant melanoma.

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