Brain Cancer section

Brain Cancer News and Features

Potential therapy found for incurable pediatric brain tumor

Scientists have developed a new potential drug therapy for a rare, incurable pediatric brain tumor by targeting a genetic mutation found in children with the cancer.

Chemotherapy after radiation slows progression of low-grade gliomas

A chemotherapy regimen of procarbazine, lomustine (CCNU), and vincristine (PCV) administered after radiation therapy improved both progression-free survival and overall survival in adults with low-grade gliomas.

Collaboration yields new methods to treat tumors with antennas

Two engineering researchers have challenged a commonly held idea about tumor ablation.

Survivors of childhood central nervous system cancer show affected self-identity

Survivors of childhood central nervous system cancer show affected self-identity

Patients treated for central nervous system (CNS) cancer during childhood or adolescence can display altered self-perception later in adulthood.

Wireless phone may increase risk of gliomas

Wireless phone may increase risk of gliomas

Risk of brain cancer is three times higher after 25 years or more of mobile phone use.

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Brain Cancer Clinical Trials

Rociletinib produces response in treatment-resistant advanced non-small cell lung cancer (NSCLC)

A new drug that targets common cancer-causing genetic mutations in patients with non-small cell lung cancer (NSCLC), and a type of the mutation responsible for treatment resistance, has shown promising results in a phase I/II clinical trial.

IDH1 mutation inhibitor first to demonstrate anticancer activity

The first drug designed to inhibit the cancer-causing activity of a mutated enzyme known as isocitrate dehydrogenase (IDH) 1 has shown clinical activity in patients with advanced acute myeloid leukemia (AML) with the IDH1 mutation.

Galeterone active in one form of castration-resistant prostate cancer

The anticancer drug galeterone has proved successful in lowering prostate-specific antigen levels in men with castration-resistant prostate cancer (CRPC).

Researchers identify biological indicator of response to new ovarian cancer drug

A method to determine which patients with ovarian cancer are more likely to respond well to the new anticancer drug rucaparib has been discovered.

Certain cases of advanced colorectal cancer respond better to three-drug regimen

Previously, patients with advanced colorectal cancer driven by a mutated version of the BRAF gene have had limited treatment options, but results from a multicenter clinical trial suggest a new option.

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