Brain Cancer section

Brain Cancer News and Features

Invisible Burdens: The Complex Needs of Caregivers of Patients With Brain Cancer

Invisible Burdens: The Complex Needs of Caregivers of Patients With Brain Cancer

Caregivers of patients with malignant brain tumors often bear additional burdens in their role, as these patients often experience cognition-related adverse effects as well as the effects of their cancer and its treatment.

Zika Virus Preferentially Targets Glioblastoma Stem Cells

Zika Virus Preferentially Targets Glioblastoma Stem Cells

Researchers have determined that, relative to differentiated tumor progeny or normal neuronal cells, ZIKV preferentially infects and kills GSCs.

Radiotherapy is Essential in Treating Brain Tumors But Associated With Significant Adverse Events

Radiotherapy is Essential in Treating Brain Tumors But Associated With Significant Adverse Events

Radiotherapy of the brain is a mainstay of brain tumor treatment; however, it affects structural network properties in the brain and can cause cortical atrophy.

Spherical Shape of New Drug Holds Promise for Bypassing the Blood Brain Barrier and Treating Aggressive Brain Cancer

Spherical Shape of New Drug Holds Promise for Bypassing the Blood Brain Barrier and Treating Aggressive Brain Cancer

An investigational drug with a novel spherical nucleic acid structure has the potential to cross the blood-brain barrier to treat glioblastoma multiforme.

Cognitively Engaging Activities Often Discontinued After Treatment of Primary Brain Tumors

Cognitively Engaging Activities Often Discontinued After Treatment of Primary Brain Tumors

Survivors of primary brain tumors tend to freely discontinue cognitively engaging activities to compensate for diminishing cognitive function after treatment completion.

Brain Cancer Clinical Trials

Novel Predictive Model More Effectively Identifies Risk for Lung Cancer

PanCan study results demonstrate the effectiveness of a novel predictive model in identifying risk of lung cancer in patients who do not meet the screening criteria of other models, including those used in the NLST.

Long-Term Eltrombopag Increases Platelet Counts, Decreases Bleeding in ITP

Previous studies determined the effectiveness of 6 months of therapy with eltrombopag in patients with ITP. In this analysis, researchers extended 4 clinical trials to assess efficacy and safety of eltrombopag therapy for more than 6 months in patients with ITP.

New Class of Clinical Trial Enhances Research on Cancer Care Delivery

What is a CCDR clinical trial and how does it differ from clinical trials that test new drugs?

Nivolumab Provides Better Long-Term Efficacy Compared With Docetaxel in NSCLC

Two phase 3 studies reveal the clinical benefit, safety profile, and overall survival of nivolumab and docetaxel for patients with squamous and nonsquamous NSCLC.

High Rates of Adverse Events Lead to Earlier Dropouts in Phase 1 Cancer Trials

Phase 1 trials are used to determine the safety profiles of treatment regimens. In this retrospective review, investigators sought to understand the reasons participants in these studies drop out.

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