Brain Cancer section

Brain Cancer News and Features

Durable Response Achieved With Nivolumab in Untreated Melanoma Brain Metastases

Durable Response Achieved With Nivolumab in Untreated Melanoma Brain Metastases

In this phase 2 study, researchers randomly assigned 79 patients with immunotherapy-naive melanoma with brain metastases to receive either nivolumab plus ipilimumab or nivolumab alone.

Prognostic Significance of Epidermal Growth Factor Receptor Expression in Glioma Patients

Prognostic Significance of Epidermal Growth Factor Receptor Expression in Glioma Patients

[OncoTargets and Therapy] A meta-analysis was conducted to evaluate the effect of abnormal EGFR expression on overall survival (OS) in patients with glioma.

Tumor-treating Fields Useful to Improve Glioblastoma Outcomes

Tumor-treating Fields Useful to Improve Glioblastoma Outcomes

Adverse event rates were similar in both trial groups, though patients treated with TTFields were much more likely to have mild to moderate skin toxicity.

History of Headache, Vomiting, Seizures Associated With Pediatric Brain Cancer

History of Headache, Vomiting, Seizures Associated With Pediatric Brain Cancer

Research pinpointed clinical factors, such as headache, that may be associated with pediatric brain neoplasms.

Drug Combination Does Not Extend Glioblastoma Survival

Drug Combination Does Not Extend Glioblastoma Survival

Lomustine plus bevacizumab may increase progression-free, but not overall, survival versus lomustine alone in progressive glioblastoma.

Brain Cancer Clinical Trials

Patient Fears of Placebo Use in Clinical Trials

What should be explained to patients regarding placebo use in controlled trials?

Cancer in Children and Adolescents (Fact Sheet)

This fact sheet reviews cancer in adolescents and children, including possible causes, treatment, and the general outlook for childhood cancers.

NP-Led Clinics Improved Phase 1 Oncology Study Operations, Outcomes

A clinic staffed with clinical research nurses provided needed care for patients in clinical trials who experienced adverse effects, and also ensured consistent documentation of treatment-related AEs, according to a presentation at the 2018 ONS Annual Congress.

Clinical Research Nursing Staff an Important Part of Oncology Clinical Trial Programs

The importance of oncology clinical research nurses in the clinical trial process was explored in a study presented at the 2018 ONS Annual Congress.

Online Program Aims to Assist With Clinical Trial Enrollment for Hematologic Cancers

A newly developed web site, described in a presentation at the 2018 ONS Annual Congress, aims to help nurses and patients explore clinical trial options for patients with hematologic cancers.

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