Bowel Cancer

Study Supports Adjuvant Chemo for Resected Stage 3 Small Bowel Cancer

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Adjuvant chemotherapy may be effective for patients with resected stage 3 small bowel adenocarcinoma and select patients with earlier stage disease.

Being overweight during teenage years may increase risk of bowel cancer

Being overweight during teenage years may increase risk of bowel cancer

Obesity during one's teenage years could greatly increase that chances of developing bowel cancer by middle age.

Most patients with bowel cancer not advised to exercise despite its health benefits

Most patients with bowel cancer not advised to exercise despite its health benefits

Many patients with bowel cancer say they were not advised to exercise regularly after diagnosis.

Bowel cancer screening less likely with low numeracy skills

Bowel cancer screening less likely with low numeracy skills

Those who have trouble understanding numbers may be less likely to undergo screening for bowel cancer.

For patients with bowel cancer, screening may extend survival despite late stage diagnosis

For patients with bowel cancer, screening may extend survival despite late stage diagnosis

Patients with late stage bowel cancer who are diagnosed through screening may have a better prognosis.

High fat diet linked to increased risk of bowel cancers

High fat diet linked to increased risk of bowel cancers

A team of researchers has found that gut bacteria associated with high fat diets cause an increased risk of bowel cancer.

Daily dose of aspirin significant lowers cancer risk

Daily dose of aspirin significant lowers cancer risk

In a recent study, researchers found that by taking a daily aspirin, the incidence of gastrointestinal cancers is reduced, as well as a reduction in cancer-specific mortality.

Existing medicines promising for stomach and bowel cancer

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Stomach and bowel cancer—two of the most common cancers worldwide—could be treated with a class of medicines that are currently used to treat a blood disorder, according to new research.

Comorbidities markedly decrease cancer survival

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Cancer survival tends to be far lower when patients have comorbid diseases, based on a systematic review of 10 years of data from Denmark and elsewhere. The effects of comorbidities on survival varied by cancer type, but overall trends were comparable, researchers said.

Regorafenib prolongs survival in face of GI cancers

Persons with metastatic colorectal cancer or gastrointestinal stromal tumors may garner some survival benefit from regorafenib after standard treatments have failed.

Early end-of-life talks mean less aggressive care later

Early end-of-life talks are associated with less aggressive care and greater use of hospice services when patients do reach their final days.

Study suggests 10-year colonoscopy rescreen not needed after first negative result

It may be reasonable to use methods other than colonoscopy to rescreen people who had negative results on their first screening colonoscopy.

Expectations too high for palliative chemotherapy

Many persons who receive chemotherapy for incurable cancers may not understand that the treatment is unlikely to be curative.

Increase in colonoscopies could explain lower rates of colorectal cancer

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The use of colonoscopy to screen for colorectal cancer may explain the significant decrease in the incidence of that cancer over the past decade. While colonoscopy is now the most common colorectal cancer screening method, evidence has conflicted about how its effectiveness compares with sigmoidoscopy.

FDA Update - September/October 2012

News from the FDA on bosutinib (Bosulif), ziv-aflibercept (Zaltrap), and everolimus oral suspension tablets (Afinitor Disperz).

New colonoscopy schedule mirrors prior advice

Two of three main recommendations for colonoscopy surveillance are now supported by stronger evidence than they were in 2006.

Race and socioeconomics impact emergency colorectal cancer diagnosis

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Among patients with colorectal cancer, 29% in a nationally representative sample were diagnosed after an emergency, such as an obstruction or perforation of the bowel.

Split-dose prep improves colonoscopy

Dividing bowel preparation solution into two doses resulted in better preparation quality, detection rates, and colonoscopy completion rates.

Patients with colorectal or bladder cancer may benefit from advanced surgical approaches

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Robotic-assisted operations and minimally invasive surgical procedures may extend survival and improve recovery in these patients compared with conventional open operations, according to recent studies presented at the 2012 Annual Clinical Congress of the American College of Surgeons.

Getting to 'the heart of the bad'

Getting to 'the heart of the bad'

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I knew Sam's joking was not a sign of joy or happiness but his way of coping, maybe the only way he knew how.

Direct-mail FOBT kits bridge colorectal screening gap

The mailing of fecal occult blood test (FOBT) kits boosted colorectal cancer screening rates in a low-income, racially diverse patient population.

Colonoscopy factors trump polyp traits in cancer risk

Characteristics of the colonoscopy rather than those of the adenomas removed may be the most significant determinants of colorectal cancer risk.

Multidrug approach fights resistance

Multidrug approach fights resistance

Research results suggest that of the billions of cancer cells that exist in a patient, only about one in a million is resistant to drugs using targeted therapy.

FDA Update - July/August 2012

News about pertuzumab injection (Perjeta); ondansetron (Zofran); carfilzomib (Kyprolis); Therascreen KRAS RGQ PCR Kit; Prostate Health Index (phi); and Prepopik

Heart drugs turn cancer cells into anticancer vaccines

Plant-based drugs primarily used in the treatment of heart failure and arrhythmias have now been found to exert anticancer effects.

Sunitinib trial for GIST shows how placebo patients can benefit, too

A key design element in a trial for sunitinib protected patients while winning the drug FDA approval for the treatment of gastrointestinal stromal tumors.

Laxative-free virtual colonoscopy can detect large polyps

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CT colonography can accurately detect adenomas 10 mm or larger in patients who did not undergo laxative-induced bowel cleansing before the procedure.

Colorectal risk defined for childhood cancer survivors

Childhood cancer survivors may need earlier colorectal cancer screening, especially if abdominal radiation was part of their treatment.

Younger CRC patients have worse presentation but comparable survival

Colorectal cancer patients under 50 had worse histological characteristics and earlier metastasis but survival equal to or better than older patients.

Virtual colonoscopy is an accurate screen in seniors

Virtual colonoscopy is an accurate screen in seniors

CT colonography accurately detects cancer and precancerous polyps in persons aged 65 years and older.

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