Bone Marrow Transplantation

Adolescent Stem Cell Donors: Benefits, Burdens, and Risks of Being a Lifeline for a Sibling

Adolescent Stem Cell Donors: Benefits, Burdens, and Risks of Being a Lifeline for a Sibling


Psychosocial support for donor siblings of bone marrow transplant patients is a significant part of the care provided by the transplant team.

Activated neutrophils may trigger potentially fatal hemorrhage associated with some cancer treatments


Blocking the passage of immune cells could prevent dangerous complications in patients undergoing transplants or chemotherapy.

Rabbit virus improves bone marrow transplants and kills some cancer cells


Researchers have discovered that a rabbit virus can deliver a one-two punch, killing some kinds of cancer cells while eliminating a common and dangerous complication of bone marrow transplants.

Short chemotherapy regimen can control immune disease after some bone marrow transplants


A short course of cyclophosphamide can not only prevent a life-threatening immune response in some bone marrow transplant recipients, but also can eliminate need for the typical 6-month round of immune suppression medicines.

New drug halves risk of graft-versus-host disease


A new class of drugs reduced the risk of patients contracting a serious and often deadly side effect of lifesaving bone marrow transplant treatments, according to a new study from researchers.

Study drug makes marrow transplant possible in relapsed leukemia

The final data from a phase II study confirmed the high degree of activity of quizartinib in persons with acute myeloid leukemia.

Anticancer agent reduces complications after stem-cell transplant

Vorinostat, already used in lymphoma, reduces the risk of graft-versus-host disease after allogeneic hematopoietic stem-cell transplantation.

New credential for blood, marrow transplant nurses

A certification program in blood and marrow transplantation nursing is being offered by the Oncology Nursing Certification Corporation, with the first BMTCN examination scheduled for February 2014.

Higher rates of chronic GVHD seen with peripheral blood stem cell transplants from unrelated donors


Among patients who receive either peripheral blood stem cells (PBMCs) or bone marrow from unrelated donors, the incidence of overall chronic graft-versus-host-disease (GVHD; 53%) is higher in those who received PBMCs than in those who received bone marrow stem cells (40%).

Mathematical model may reduce infections from chemotherapy


A new mathematical model suggests that proper risk assessment for the risk of infection with cancer chemotherapy needs to evaluate both the quantity and quality of white blood cells. The model was built by Weizmann Institute mathematicians in collaboration with physicians from the Meir Medical Center in Kfar Saba and from the Hoffman-La Roche research center in Basel, Switzerland.

HIV drug can prevent complications after stem-cell transplant

An HIV drug helped lower the risk of graft-versus-host disease in persons with blood cancer who had stem-cell transplants to rebuild bone marrow.

Young adults with leukemia did best on pediatric treatment regimens

Persons aged 16-39 with acute lymphoblastic leukemia fared better with pediatric-inspired chemotherapy regimens than with typical adult treatment.

More chemotherapy might be best move for some children with leukemia

When induction therapy fails in acute lymphoblastic leukemia, some youths have better outcomes with more chemotherapy than with stem cell transplant.

Many women with cancer missing fertility risk info, services

Few women of childbearing age who are diagnosed with cancer are taking steps to preserve their fertility during treatment.

Exploring holistic medicine: Using acupuncture to relieve cancer-related fatigue

Exploring holistic medicine: Using acupuncture to relieve cancer-related fatigue


The ancient Eastern medicinal art can relieve one of the most distressing effects of cancer and cancer treatment: fatigue.

CDC focuses on infection prevention

CDC focuses on infection prevention

A new initiative launched by CDC is designed to reduce the risk of life-threatening infection in cancer patients undergoing chemotherapy.

Older blood cancer patients may benefit from cell transplant regimen

A regimen using minimal-intensity radiation therapy before bone marrow or stem cell transplantation may work for older patients who cannot tolerate stronger pretransplant treatment.

Family studies reveal leukemia gene

A genetic defect found on the GATA2 gene predisposes people to acute myeloid leukemia (AML) and myelodysplasia, researchers have learned.

New hope for half-match bone marrow transplant in blood cancer

A small study has demonstrated an improved process for making half-matched bone marrow or stem cell transplants for persons with blood cancer more successful.

Modified stem cells protect healthy tissue from brain cancer treatment

Glioblastoma treatment may be made more effective by introducing a chemotherapy-resistant gene into normal bone marrow stem cells to protect them from the toxic effects of chemotherapy.

A classic novel is the premise of a 2-day orientation to the BMT unit

The program, outlined by Lisa Privitere, RN, BSN, OCN®, BMT, RPCI, and colleagues, in a presentation at the Oncology Nursing Society 36th Annual Congress, follows the story of a young girl (the orientee) on an adventure attempting to make sense of her new world, growing up and forever being changed to the White Rabbit (the preceptor) carrying a watch, always in a hurry.

Inhibiting "anchor" molecule in stem cells may improve marrow transplant process

The safety and efficiency of bone marrow transplants may improve due to the discovery of a rare molecule that establishes blood stem cells in their niche within the bone marrow.

Disparities across gender and race for BM transplantation

Disparities across gender and race for BM transplantation

A study published in Cancer found that African-Americans and women are less likely to undergo bone marrow transplantation to treat their cancer.

New technology offers alternative to painful bone marrow procedures


The OnControl Bone Marrow System has been made available by Vidacare for use by clinicians to perform bone marrow aspiration and biopsy procedures.

Innovative Strategy Improves Immune Recovery of Mismatched Transplants


Scientists have improved a method for bone marrow transplantation from mismatched donors that would help restore the immune system quicker, according to findings presented at the American Society of Hematology Annual Meeting and Exposition in New Orleans in December.

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