Blood And Marrow Transplantation

Bone Marrow vs Bloodstream: Stem Cell Source Influences Transplantation Outcomes

Bone Marrow vs Bloodstream: Stem Cell Source Influences Transplantation Outcomes

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Blood stem cells derived from donor bone marrow resulted in better self-reported psychological well-being and fewer GVHD symptoms.

Recently Identified Biomarkers Found to Warn of Chronic Graft-vs-Host Disease in Marrow Transplant Patients

Recently Identified Biomarkers Found to Warn of Chronic Graft-vs-Host Disease in Marrow Transplant Patients

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Researchers recently identified CXCL10, a protein that could act as a biomarker for chronic graft-versus-host disease (cGVHD), a long-term adverse effect that develops in some patients after undergoing blood and bone marrow transplant.

Bone Marrow vs PBSCs: Preference of Stem Cell Source for Bone Marrow Failure Varies Worldwide

Bone Marrow vs PBSCs: Preference of Stem Cell Source for Bone Marrow Failure Varies Worldwide

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Sources of stem cells used to treat bone marrow failure vary around the world, with bone marrow harvest more commonly used in areas with more resources. PBSCs are more commonly used in regions with limited resources.

Teamwork Improves Transitioning Blood, Marrow Transplant Patients to Outpatient Unit

Teamwork Improves Transitioning Blood, Marrow Transplant Patients to Outpatient Unit

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Nursing staff satisfaction improved in transition of care for patients from the inpatient to the outpatient blood and marrow transplant (BMT) units.

Managing Aspergillus infection in HSCT recipients

Managing Aspergillus infection in HSCT recipients

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This review discusses common risk factors, treatment, and preventive measures for aspergillosis in hematopoietic stem transplantation recipients.

A subset of antiviral immune cells could prevent CMV infections in bone marrow transplant recipients

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A small subset of antiviral immune cells may be enough to fight and even prevent the disease caused by cytomegalovirus (CMV) in patients that receive bone marrow transplants.

New test helps guide treatment for bone marrow transplant patients with GVHD

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A new test can assist in the treatment of patients with graft-versus-host disease (GVHD), an often life-threatening complication of bone marrow and stem cell transplants.

Positive study data could improve standard of care for Hodgkin lymphoma

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Patients with Hodgkin lymphoma who received brentuximab vedotin after transplantation lived longer without disease progression than patients who received only supportive care, per clinical trial data.

Early detection helps manage chronic graft-vs-host disease complication

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A simple questionnaire that rates breathing difficulties on a scale of 0 to 3 predicts survival in chronic graft-vs-host disease, according to a new study.

Sexual health diminished after bone marrow transplant

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Preparative procedures and complications associated with blood or bone marrow transplantation have been tied to diminished sexual health in both men and women, according to new research.

New credential for blood, marrow transplant nurses

A certification program in blood and marrow transplantation nursing is being offered by the Oncology Nursing Certification Corporation, with the first BMTCN examination scheduled for February 2014.

Higher rates of chronic GVHD seen with peripheral blood stem cell transplants from unrelated donors

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Among patients who receive either peripheral blood stem cells (PBMCs) or bone marrow from unrelated donors, the incidence of overall chronic graft-versus-host-disease (GVHD; 53%) is higher in those who received PBMCs than in those who received bone marrow stem cells (40%).

New tool determines "readiness to die" of leukemia cells

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A novel method has been developed to determine how ready acute myeloid leukemia (AML) cells are to die. This discovery may help to more effectively choose treatment options for patient with AML.

Melanoma risk increased for transplant and lymphoma patients

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The immune systems of transplant recipients and lymphoma patients tend to be significantly depressed, making these patients more susceptible to melanoma, according to a review on the role of immunosuppression in melanoma.

Race affects the likelihood of finding a suitable stem cell donor

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Greater difficulty exists in finding matched, unrelated donors for nonwhite patients who are candidates for hematopoietic cell transplantation (HCT), according to a study by researchers at the Moffitt Cancer Center.

Persistent headache plagues an immunocompromised patient

Persistent headache plagues an immunocompromised patient

Imaging studies and laboratory tests were negative, but lumbar puncture revealed the cause of this patient's unexplained neurologic symptoms.

GVHD in pediatric HSCT patients: Clinical trials for Rituximab

GVHD in pediatric HSCT patients: Clinical trials for Rituximab

The CD20 antagonist is a potentially effective preventive and treatment for this common adverse effect of hematopoietic stem cell transplantation.

FDA Update: May/June 2012

Drug Safety Communication on lenalidomide (Revlimid); FDA approval for pazopanib (Votrient)

Modified stem cells keep glioblastoma at bay

Three patients with glioblastoma lived longer than predicted after receiving transplants of their own blood stem cells that had been gene-modified.

Leukemia: Understanding its types and treatments

Leukemia: Understanding its types and treatments

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This review describes the four major groups of leukemia, plus diagnostic tests and treatment regimens for each group.

Workgroup identifies needs, challenges to future growth of BMT nursing workforce

Challenges to the future growth of allogeneic blood and marrow transplants (BMT)—currently, more than 20,000 are performed annually in the United States alone—include workforce shortages and lack of adequate infrastructure, according to a presentation during the Oncology Nursing Society 36th Annual Congress.

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