Biopsy

Artificial Intelligence Method Improves Mammography Readings

Artificial Intelligence Method Improves Mammography Readings

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Natural language processing (NLP) software correlated key characteristics expressed verbally in mammography reports with pathologic findings, providing an accurate indication for biopsy referral.

Novel Radiotracer Is Near Perfect in Detecting Sentinel Lymph Node in Breast Cancer

Novel Radiotracer Is Near Perfect in Detecting Sentinel Lymph Node in Breast Cancer

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A novel sentinel lymph node (SLN) radiotracer, 99mTC-rituximab, demonstrated nearly 100% detection/success rate in SLN and metastasis in breast cancer.

Identifying Smaller ctDNA Fragments Improves Sensitivity of Liquid Biopsy

Identifying Smaller ctDNA Fragments Improves Sensitivity of Liquid Biopsy

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Circulating tumor DNA (ctDNA) has shorter fragment sizes than DNA fragments from healthy cells that have died, and this may increase the clinical utility of liquid biopsies.

Fluid-Based Biomarkers Found Highly Predictive of Diagnosis and Prognosis in Prostate Cancer

Fluid-Based Biomarkers Found Highly Predictive of Diagnosis and Prognosis in Prostate Cancer

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Analysis of proteins identified in urine has led to the discovery of proteomic signatures for prostate cancer that have the potential to serve as highly accurate noninvasive biomarkers that can identify aggressive disease before surgery.

PET/CT Hybrid Imaging Technique Provides Accurate Guide for Prostate Cancer Biopsy

PET/CT Hybrid Imaging Technique Provides Accurate Guide for Prostate Cancer Biopsy

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Prostate-specific molecular imaging at initial biopsy and preoperative planning can accurately determine and delineate the extent of prostate cancer. The imaging technique was a type of PET/CT called 68Ga-PSMA PET/CT.

Extent of Resection Influences Length of Progression-Free Survival in Glioblastoma

Extent of Resection Influences Length of Progression-Free Survival in Glioblastoma

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Gross total resection to treat glioblastoma multiforme (GBM) showed progression-free survival benefits over subtotal resection and biopsy in a meta-analysis of 37 studies.

Liquid Biopsy Found Comparable to Standard Tissue Biopsy in Identifying BRAF V600 Mutation Status

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Plasma from a blood draw can be used to test for BRAF V600 mutations in advanced cancers in just 90 minutes, and results were comparable to using tissue biopsy.

Liquid Biopsy Provides A More Comprehensive View of Genetic Changes Occurring in Cancer Tumors

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Analyzing tumor DNA fragments in the bloodstream, known as circulating tumor DNA (ctDNA), may offer a more complete view of a patient's cancer from a molecular perspective.

Renal Mass Biopsy Proves Accurate for Small Renal Masses

Renal Mass Biopsy Proves Accurate for Small Renal Masses

For smaller renal masses sized at 4 cm or less, mass biopsy is accurate.

Few Patients Wish to Receive Skin Cancer Biopsy Results in Person

Few Patients Wish to Receive Skin Cancer Biopsy Results in Person

Patients with suspected malignant melanoma or squamous cell carcinoma prefer other means to receive their biopsy results than face-to-face.

Novel Diagnostic Test Uses CTCs in Blood to Guide Treatment Decisions for Patients With Prostate Cancer

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An experimental liquid biopsy using a blood sample may determine which patients with prostate cancer will benefit from hormone therapies.

Mandatory Biopsy May Hinder Eligibility of Potential Participants in Cancer-related Clinical Trials

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Mandatory tumor tissue specimens and associated analyses for clinical trial participation appear to be a significant barrier to clinical trial enrollment and may delay treatment.

Extra Biopsies in Clinical Trials Often Have No Impact on Drug Dose or Use in Cancer Treatments

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Extra biopsies performed solely to study the pharmacodynamics of a new anticancer drug have no impact on subsequent drug development or on how physicians use these new drugs to treat future patients.

Blood Sample Offers a New Way of Detecting Cancer

Blood Sample Offers a New Way of Detecting Cancer

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RNA test of blood platelets can detect, classify, and pinpoint the location of cancer by analyzing a sample equivalent to 1 drop of blood. Using this new method, researchers were able to identify cancer with 96% accuracy.

Liquid Biopsy of Cerebrospinal Fluid More Effective in Managing Brain Tumors

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Liquid biopsy of cerebrospinal fluid has potential for prognosis, treatment, identification, and tracking of brain tumor genomic alterations both in real time and over time.

Blood Test Identifies Mutations Behind Drug Resistance in Patients Taking Antiandrogen for Prostate Cancer

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Scientists developed a blood test that can identify key mutations driving resistance to a widely used prostate cancer drug and which patients will not respond to the treatment in advance.

Blood Source May Explain Low Numbers of Circulating Tumor Cells in Liquid Biopsies

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The mystery of unexpectedly low numbers of CTCs in a liquid biopsy may be explained by whether the blood is drawn from a vein or an artery.

Novel biopsy procedure may offer early detection of cancer of the esophagus

Novel biopsy procedure may offer early detection of cancer of the esophagus

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New procedure allows doctors to collect cells from all along the esophagus, whereas standard biopsies take individual point samples.

Novel test combines two markers with prostate-specific antigen (PSA) for improved prostate cancer detection

Novel test combines two markers with prostate-specific antigen (PSA) for improved prostate cancer detection

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A new test that employs urine analysis demonstrated improved prostate cancer detection over traditional models based on prostate-specific antigen (PSA) levels.

Liquid biopsy: A new tool in the management of NSCLC

Liquid biopsy: A new tool in the management of NSCLC

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This developing technology allows serial monitoring to better gauge response to treatment and prognosis for patients with non-small cell lung cancer.

New device for faster skin biopsy without anesthesia

New device for faster skin biopsy without anesthesia

Currently a skin biopsy can take approximately 30 minutes to perform, but a new device under development could reduce that time greatly.

Multidisciplinary Bone Marrow Program Prepares Nurses for Aspirations, Biopsies

Multidisciplinary Bone Marrow Program Prepares Nurses for Aspirations, Biopsies

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Registered nurses in a bone marrow program maintained a 98% score for the quality of bone marrow aspiration and biopsy sample.

Teens with breast lumps may be able to avoid invasive biopsy

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The use of breast ultrasound could eliminate the need for biopsy in many cases in adolescent girls, according to a recent study.

MRI detection of sugar molecules on cells may enable distinction of cancer vs noncancerous cells

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Study data suggests that magnetic resonance imaging (MRI) could one day make biopsies more effective, or even replace them altogether, via noninvasive detection of telltale sugar molecules shed by the outer membranes of cancerous cells.

Study examined diagnostic accuracy of breast biopsy interpretations

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A comparison of the diagnostic interpretation of breast biopsy slides by pathologists and that of an expert consensus panel yielded an overall agreement of 75%.

Blood samples may serve as surrogates for tumor biopsies in patients with lung cancer

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A study examined the feasibility of using circulating free DNA (cfDNA) from blood samples of patients with advanced non-small cell lung cancer as a surrogate for tumor biopsies.

Targeted MRI-ultrasound is better than standard biopsy at detecting high-risk prostate cancer

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Targeted magnetic resonance (MR)/ultrasound fusion biopsy outperformed standard biopsy technique for increased detection of high-risk prostate cancer, according to a recent study.

Novel breast cancer risk prediction model is more accurate than current model

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A new breast cancer risk model that combines histologic features of biopsied breast tissue from women with benign breast disease and individual patient demographic information more accurately classified breast cancer risk.

Combination prostate biopsy could yield improved results

Combination prostate biopsy could yield improved results

Prostate biopsies that combine both magnetic resonance imaging (MRI) technology and ultrasound appear to give more accurate results, according to a new study.

Biopsies with DCIS diagnosis increase for women undergoing mammography

Biopsies with DCIS diagnosis increase for women undergoing mammography

Biopsy frequency went up after diagnostic, but not screening, mammographies.

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