ADD THIS DRUG TO MY LIST

Select the drug indication to add to your list

AZACTAM
Bacterial infections
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:

AZACTAM Rx

Generic Name and Formulations:
Aztreonam 1g, 2g; for IM or IV inj after reconstitution; sodium-free.

Company:
Bristol-Myers Squibb

Therapeutic Use:

Indications for AZACTAM:

Susceptible bacterial infections, including septicemia, lower respiratory tract, complicated or uncomplicated urinary tract, skin and skin structure, gynecologic, intraabdominal. Surgical adjunct.

Adult:

UTI: 500mg–1g every 8–12hrs. Other systemic infections: moderately severe: 1–2g every 8–12hrs; severe: 2g every 6–8hrs. All: max 8g/day. Max 1g/dose by IM. Renal impairment (CrCl 10–30mL/min): Halve dose after loading dose; CrCl <10mL/min: see full labeling.

Children:

<9 months: not established. Not for septicemia or certain skin and skin structure infections; see full labeling. 9 months–16yrs (normal renal function only): Urinary tract, lower respiratory tract, intraabdominal, gynecologic infections: mild-to-moderate: 30mg/kg IV every 8hrs; moderate-to-severe: 30mg/kg IV every 6–8hrs; max 120mg/kg/day. May need higher dose in patients with cystic fibrosis.

Warnings/Precautions:

Penicillin, cephalosporin, carbapenem, or other allergy. Renal or hepatic impairment; monitor during therapy. Monitor renal function in prolonged use or with high doses. Elderly. Pregnancy (Cat.B). Nursing mothers.

Interactions:

May potentiate nephrotoxicity of concomitant aminoglycosides. Avoid concomitant β-lactamase-inducing drugs (eg, cefoxitin, imipenem).

Pharmacological Class:

Monobactam.

Adverse Reactions:

Local reactions (eg, phlebitis, discomfort), GI upset, rash, anaphylaxis, blood dyscrasias, elevated liver enzymes or serum creatinine; C. difficile-associated diarrhea; rare: toxic epidermal necrolysis.

How Supplied:

Single-dose vials (15mL)—10; GALAXY containers (50mL)—24

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs