Astrocytoma

IDH gene may serve as prognostic marker in anaplastic astrocytoma

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New research indicates that the IDH1 gene might be a prognostic marker for a rare form of brain cancer.

Gene mutation defines brain tumors that benefit from aggressive surgery

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Patients with malignant astrocytoma whose tumors carry the gene mutation IDH1 may benefit greatly from surgical removal of the largest possible amount of tumor.

Brain tumors in children have a common cause

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When 96 pilocytic astrocytomas were analyzed by whole-genome sequencing, all had MAPK-pathway alterations. This indicates that pilocytic astrocytoma is predominantly a single-pathway disease.

Genetic pathways may suggest more effective targeted therapies for childhood brain tumors

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A new study offers glimpses into how scientists will be using the ongoing flood of gene-sequencing data to customize treatments based on very specific mutations in a child's tumor.

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