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ASMANEX HFA
Asthma/COPD
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Drug Name:

ASMANEX HFA Rx

Generic Name and Formulations:
Mometasone furoate 100mcg, 200mcg; per actuation; metered-dose inhaler with dose counter.

Company:
Merck & Co., Inc.

Therapeutic Use:

Indications for ASMANEX HFA:

Maintenance treatment of asthma as prophylactic therapy.

Limitations Of use:

Not for relief of acute bronchospasm.

Adult:

Previously on inhaled medium-dose corticosteroids: use 100mcg strength. Previously on inhaled high-dose or oral corticosteroids (wean gradually): use 200mcg strength. For both: Two inhalations twice daily (AM & PM). Rinse mouth after use.

Children:

Not established.

Contraindications:

Primary treatment of status asthmaticus or acute asthma attacks.

Warnings/Precautions:

Maintain regular regimen. Prescribe a short-acting, inhaled β2-agonist for acute symptoms; monitor for increased need. Re-evaluate immediately during rapidly deteriorating asthma; may need oral corticosteroid therapy. Immunosuppressed. Untreated infections (eg, fungal, bacterial, viral, parasitic), TB, ocular herpes simplex. If exposed to chickenpox or measles, consider anti-infective prophylactic therapy. Transferring from systemic steroids: taper gradually. If adrenal insufficiency exists following systemic corticosteroids, replacement with inhaled steroids may exacerbate symptoms of adrenal insufficiency (eg, lassitude). Monitor for increased intraocular pressure, glaucoma, and/or cataracts; bone mineral density if other osteoporosis risk factors exist; and for growth suppression in children; hypercorticism and HPA axis suppression (if occurs, discontinue gradually). Severe hepatic impairment. Labor & delivery. Pregnancy. Nursing mothers: not recommended.

Interactions:

Potentiated by ketoconazole or other strong CYP3A4 inhibitors (eg, ritonavir, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, saquinavir, telithromycin); use caution.

Pharmacological Class:

Steroid.

Adverse Reactions:

Nasopharyngitis, headache, sinusitis, bronchitis, influenza; hypersensitivity reactions, paradoxical bronchospasm; discontinue if occurs.

Generic Availability:

NO

How Supplied:

Inhaler—13g (120 inh)

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