Ask a Pharmacist Articles
Why is a type and crossmatch needed before starting patients on treatment with daratumumab (Darzalex)?
Which vaccines should be avoided in patients receiving chemotherapy?
I hear the term "financial toxicity" used more and more when people are discussing the cost of cancer treatments. What exactly is financial toxicity?
I was surprised to see an order for arsenic recently. What is this being used for?
What precautions should be taken to prevent tumor lysis syndrome (TLS) in patients receiving venetoclax (Venclexta)?
There is a lot of talk about biosimilar drugs. What makes a drug a biosimilar?
What is the interaction between oral chemotherapy and GERD medicines?
How should side effects of the new checkpoint inhibitor drugs be managed?
At my current clinic, hydration and mannitol are administered before premedications on a cisplatin regimen; at previous clinic, premeds and hydration were administered before mannitol. Does it make a difference?
Chemotherapy agents are sometimes required to be administered in a specific sequence. What factors influence the need to follow a specific sequence?
What factors should be considered when calculating an adequate postmedication flush to deliver complete, accurate doses of small-volume IV medications to our patients?
Some of our patients receive olanzapine (Zyprexa) as an antiemetic. Is this a typical use of this drug?
During the summer, many patients with CML who are taking oral chemotherapy drugs have questions about taking their drugs while traveling. What advice can we give them regarding this?
How is loratadine used to treat bone pain in patients receiving white blood cell growth factors?
Why do the antibody drugs have such long names?
Patients periodically ask about the use of marijuana in cancer treatment. Is there any data about this?
What are the most effective treatments for MS pain in patients with co-existing cancer?
How should severe mucositis from capecitabine (Xeloda) be managed?
Why do some drugs need a micron filter and what is the affect of using one?
When giving gemcitabine (Gemzar) and cisplatin (Platinol), is it better to give gemcitabine first to reduce myelosuppression with every indication?
In what sequence should you administer premedications prior to paclitaxel: Should the antihistamine be given first or the steroid?
What are the treatment options for recurrent metastatic HER2-positive breast cancer after trastuzumab therapy?
What are the best practices to reduce venous irritation and delayed irritation?
The furanocoumarins in grapefruits interact with some medications—does eating a grapefruit allow for lower drug dosages?
What would you recommend for a patient with terminal agitation?
Is combination therapy of imatinib (Gleevec) and radiotherapy safe?
Has any medicine or supplement been shown to help lessen the severity of vincristine-related peripheral neuropathy?
A patient on adjuvant endocrine therapy for breast cancer is complaining of hair loss. Could the alopecia be due to her endocrine therapy?
Can the drug paroxetine mesylate (Brisdelle, Paxil) be given to patients taking a chemoprevention drug such as raloxifene (Evista) or any of the aromatase inhibitors?
Which cancer treatments can cause other cancers later in life?
Which patients, if any, should receive prophylactic antibiotics when starting therapy with epidermal growth factor receptor (EGFR) inhibitors?
What are some of the potential autonomic issues related to acute neurotoxicity from oxaliplatin?
What should nurses be aware of when administering denosumab?
Does consumption of regular orange juice cause drug interactions, or should all citrus fruits be avoided?
Which medicines can be split or crushed for administration?
How are drugs classified as controlled substances?
Folic acid can interfere with certain chemotherapy drugs. Is there an acceptable level of folic acid or should it be avoided completely?
Methylprednisolone (Solu-Medrol) and hydrocortisone (Solu-Cortef) are used to treat infusion reactions to chemotherapy and other anticancer treatments. Some clinicians seem to favor one over the other. Is there a significant difference between the two or is it just a matter of clinician preference?
The Advisor Forum addresses a question about medications that can treat hot flushes in women receiving tamoxifen.
Our pharmacist answers a question about a potential interaction between certain citrus juices and drug metabolism.
What is the role of sunitinib malate in the treatment of sarcomas?
When opioids or other painkillers prescribed after surgery or an injury are no longer needed, or if a medication was changed, patients may have unused prescription medications in their homes. Is there a safe way for patients to dispose of these leftover prescriptions?
Is there any information about a link between lisinopril and breast cancer recurrence?
What are some common reasons for delayed methotrexate clearance after a 24-hour infusion?
What are the potential problems associated with infusing paclitaxel without an inline filter?
Do all tumor necrosis factor medications for rheumatoid arthritis require 1.2 micron filter tubing?
What are the benefits of probiotics? Does any particular kind offer more benefits than the others?
What specific visual changes are associated with the new drug crizotinib and what causes them?
What is the risk for endometrial cancer in a patient taking tamoxifen to reduce recurrence of ER/PR positive breast cancer after treatment?
What exit strategy do you recommend for discontinuing opioid therapy?
How does the CYP3A4 pathway impact metabolism of the new oral targeted agents in oncology?
What effect does pentamidine have on glucose control?
What actions are being taken in regard to current shortages of chemotherapeutic agents?
Should patients receive a test dose of bleomycin? If yes, should the test dose be administered with every dose or just the initial dose?
How can chemo brain be managed?
What data are there to support the use of noni in oncology patients? Can it be incorporated safely with chemotherapy?
Who should receive a test dose prior to a full-dose iron infusion?
What should nurses be aware of when administering denosumab? What are the best strategies for managing vaginal dryness caused by hormonal therapy for breast cancer?
What role does medication play in managing fatigue? Can neuropathy from oxaliplatin therapy be effectively treated or prevented?
This month's questions: Giving Neulasta on the day of chemotherapy and strategies for managing opioid induced constipation.
Studies show that alternate dosages of fulvestrant may be efficacious, and adverse effects are similar in all regimens.
This month's questions: retreating with rituximab after an allergic reaction and administering the new prostate cancer immunotherapy.
The author summarizes the uses of methadone for cancer pain and olanzapine for chemotherapy-induced nausea and vomiting.
A few simple practices can help patients dispose of old and unused medications in a way that is safest for people, pets, and the environment.
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