ASH 2011 Conference Coverage

Ofatumumab With Fludarabine, Cyclophosphamide Approved for Relapsed CLL

The US Food and Drug Administration has approved ofatumumab in combination with fludarabine and cyclophosphamide for the treatment of relapsed chronic lymphocytic leukemia (CLL).

Study Affirms Activity of Ibrutinib in Patients With R/R CLL With 17p Deletion

Treatment with ibrutinib is associated with a high overall response rate in patients with relapsed or refractory chronic lymphocytic leukemia (CLL) and 17p deletion.

Ruxolitinib Effective as Long-term Treatment Option for Polycythemia Vera

Ruxolitinib is an effective long-term treatment option for patients with polycythemia resistant or intolerant to hydroxyurea, according to a study presented at the 2016 European Hematology Association Congress.

Definitive IMRT Associated With Shorter Feeding Tube Placement Duration in HNC

Patients with head and neck cancer treated with IMRT had a significantly shorter duration of feeding tube placement compared with those who received 3DRT.

SBRT Improves Overall and Disease-Specific Survival in Stage I NSCLC

Continued adoption of stereotactic body radiation therapy (SBRT) to treat early stage NSCLC improved OS and lung cancer-specific survival, according to a study presented at the 2016 annual meeting of the American Society for Radiation Oncology.

Patients Receiving RT in APBI Facilities Despite Eligibility for Observation

Patients with early stage breast cancer who received breast-conserving surgery and were eligible for observation were more likely to undergo adjuvant radiotherapy in facilities performing APBI.

Prolonged Imatinib Therapy Improves Likelihood of Deeper Molecular Response

In patients with chronic myeloid leukemia in chronic phase, prolonged treatment with imatinib helps to achieve a deeper molecular response over 5 years.

TKI-intolerant Patients With CLL Can Successfully Receive an Alternate TKI

Patients with chronic lymphocytic leukemia (CLL) who discontinue TKI therapy due to toxicity can successfully be treated with an alternate TKI.

ASCO, ASTRO Issue Guideline Update for Postmastectomy RT

The American Society of Clinical Oncology, American Society for Radiation Oncology, and Society of Surgical Oncology have issued a joint consensus guideline update for the use of radiotherapy following mastectomy in patients with breast cancer.

Study Assesses Efficacy of Ramucirumab in HCC by Child-Pugh Score

In patients with advanced HCC and a baseline αFP level of 400 ng/mL or more, a survival benefit with second-line ramucirumab therapy was observed for those with Child-Pugh scores of 5 and 6.

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