ASH 2010 Conference Coverage

Spotlight on Triptorelin in the Treatment of Premenopausal Women with Early-Stage Breast Cancer

[Breast Cancer: Targets and Therapy] This research examines the role of LHRH analogs in the medical treatment of premenopausal women with early breast cancer.

Redefining Prognosis for Hematologic Cancers in Older Adults by Age

A report on how variations in the effects of geriatric syndromes and aging can affect treatment modality choices and outcomes for the eldest older adults with hematologic cancers.

Outcomes for Elderly With Hematologic Cancers Effected by Cognitive Impairments

Study data suggest that cognitive impairments may be associate with worse survival among patients with hematologic cancer.

Evolving Role of Radiation Therapy in the Treatment of Mesothelioma

Research into the potential of radiation therapy in the management of mesothelioma may improve the prognosis, and possibly extend progression-free survival, for patients with this incurable cancer.

FDA Approves Fostamatinib for ITP After Insufficient Response to Previous Treatment

The US FDA granted approval to fostamatinib (Tavalisse), a kinase inhibitor, for the treatment of thrombocytopenia in patients with chronic IPT who have had an insufficient response to a previous treatment.

Elderly Patients Are Underrepresented in Trials For Soft Tissue Sarcoma

With median age of participants in clinical trials for soft-tissue sarcoma younger than most patients who develop the disease, these researchers sought to determine the prevalence of including persons older than 65 in clinical trials and the efficacy of first-line chemotherapy for STS in older patients.

Combination Effective as First-Line Therapy in Advanced ER-Positive HER2-Negative Breast Cancer

In this open label phase 2 BOLERO-4 study, researchers evaluated the effect of everolimus plus endocrine therapy on progression-free survival.

In Older Women With Breast Cancer QoL May Predict 10-Year Mortality

A model that incorporates HRQOL was found to outperform a model that only employs traditional prognostic variables.

Screening Colonoscopy Improves CRC-Related Mortality in Veterans

Researchers conducted a case-control study to determine whether colonoscopy is associated with decreased CRC mortality in veterans and whether its effect differs by anatomical location of CRC.

Progression-Free Survival Extended With PANEX Protocol in R/R Multiple Myeloma

This treatment-expansion study evaluated the tolerability and safety of the PANEX (panobinostat plus bortezomib with dexamethasone) protocol in heavily treated patients with R/R multiple myeloma.

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