ASH 2010 Conference Coverage

Chemotherapy-related Bone Loss in Children With ALL Occurs Earlier Than Previously Assumed

Significant bone loss in children receiving chemotherapy for acute lymphoblastic leukemia (ALL) occurs during the first month of treatment.

Data Analysis Shows 8-week Chemoradiotherapy-to-Surgery Timeline Achieves Optimal Tumor Response

Overall survival was best and resection of residual locally advanced rectal tumors most successful when surgery occurred at precisely 8 weeks, or 56 days, after completion of chemoradiotherapy.

Exercise During Neoadjuvant CRT Less Difficult Than Anticipated for Rectal Cancer

Patients with rectal cancer reported aerobic exercise during neoadjuvant chemoradiotherapy to be more enjoyable and less difficult.

Early Onset of Everolimus Adverse Events Requires Thorough Patient Education

Almost half of patients with metastatic HR-positive breast cancer treated with everolimus and exemestane required a dose reduction.

Nanoparticle System Uses Light Waves to Target Release Site of Drug

Nanoparticles that release a drug only when exposed to near-infrared (NIR) light are a promising drug-delivery agent developed by Canadian researchers.

Delirium is Common in Older Patients Undergoing GI Surgery

Older patients undergoing gastrointestinal surgery often experience postoperative delirium. In an analysis of 11 studies, incidence of postoperative delirium ranged from 8.2% to 54.4%.

Nanoparticle Drug Delivery Aims to Control Pancreatic Tumor and Inhibit Escape Pathways

Use of a nanoparticle to deliver drugs may reduce tumors and suppress metastatic escape. These efforts offer a way to control drug release over space and time while reducing systemic drug exposure and the associated side effects.

Better Approaches to Patient Counseling of BRCA Gene Mutation Carriers Needed

An in-depth look at the issues associated with the care reveals a need to improve how clinicians can help these women sort through their options.

Meditation May Reduce Breast Biopsy Pain

Listening to guided meditation significantly reduced biopsy pain during imaging-guided breast biopsy.

Dasatinib, Nilotinib, Ponatinib Increase Vascular Occlusive Events

Dasatinib, nilotinib, and ponatinib, used in the treatment of patients with chronic myeloid leukemia (CML) increase vascular occlusive events.

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