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ASCOMP w. CODEINE
Migraine and headache
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Drug Name:

ASCOMP w. CODEINE CIII

Generic Name and Formulations:
Codeine phosphate 30mg, butalbital 50mg, aspirin 325mg, caffeine 40mg; caps.

Company:
Breckenridge Pharmaceutical, Inc.

Therapeutic Use:

Indications for ASCOMP w. CODEINE:

Tension (or muscle contraction) headache.

Adult:

1–2 caps every 4 hours, as needed; max 6 caps/day. Use lowest effective dose for shortest period of time.

Children:

Not recommended.

Contraindications:

NSAID allergy. Porphyria. Bleeding or coagulation disorders. Peptic ulcer.

Warnings/Precautions:

Renal or hepatic impairment; monitor liver/renal function tests. Acute abdomen. Asthma. Bleeding disorders. Head injury. Increased intracranial pressure. Impaired thyroid or adrenocortical function. GI or GU obstruction. Ultra-rapid metabolizers of codeine (may experience overdose symptoms). Drug abusers. Elderly. Debilitated. Labor & delivery. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

CNS effects may be enhanced by MAOIs. Concomitant corticosteroids: withdrawal of corticosteroid may result in salicylism. May potentiate oral anticoagulants, oral antidiabetics and insulin, 6-mercaptopurine and methotrexate, NSAIDs, other narcotic analgesics, alcohol, general anesthetics, tranquilizers, sedative-hypnotics, other CNS depressants. May diminish effects of uricosuric agents.

Pharmacological Class:

Opioid + barbiturate + salicylate + stimulant.

Adverse Reactions:

Drowsiness, dizziness, intoxicated feeling, GI upset/pain.

How Supplied:

Caps—100, 500

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