Anti-Cancer Activity

Antioxidants may not fight cancer, according to research

Antioxidants may not fight cancer, according to research

A research meta-analysis suggests that the anti-cancer properties of antioxidants may have been overstated, and that, in some cases, antioxidants could even have an adverse effect with regard to cancer.

The best cream for coffee may be the growing evidence of its cancer-preventive properties

The best cream for coffee may be the growing evidence of its cancer-preventive properties

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Can one of the most popular beverages in the world limit or even prevent the growth of certain cancers?

Antioxidants and Cancer Prevention (Fact Sheet)

Antioxidants and Cancer Prevention (Fact Sheet)

This fact sheet explores possible relationships between antioxidants and cancer prevention.

Antioxidants may not be an effective preventive measure against cancer

Antioxidants may not be an effective preventive measure against cancer

Researchers from the Lustgarten Foundation and Feinberg School of Medicine at Northwestern University offer an explanation of why antioxidant supplements may do more harm than good in regard to reducing cancer development.

Inhibitor of cholesterol biosynthesis may have potential as breast cancer treatment

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A compound initially developed as a treatment for high cholesterol not only halts the progression of breast cancer, but also can kill cancer cells.

Signalling pathway may send cancer's cellular factories into overdrive

Signalling pathway may send cancer's cellular factories into overdrive

Scientists identified a molecular trigger that prompts the unrestricted cell growth in cancer. A protein in the TOR signaling pathway, SREBP, controls the flow of messages to the endoplasmic reticulum (ER) to produce enough proteins and lipids to support nonstop growth.

Aspirin and smoking influence aging processes connected to cancer

Aspirin and smoking influence aging processes connected to cancer

Researchers from the University of Basel were able to show that aspirin use and smoking both influence aging processes of the female genome that are connected to colorectal cancer.

Limiting carbs may reduce breast cancer recurrence in some women

Limiting carbs may reduce breast cancer recurrence in some women

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Reducing carbohydrate intake could reduce the risk of breast cancer recurrence among women whose tumor tissue is positive for the insulin-like growth factor-1 (IGF1) receptor, according to a new study.

Diets high in dairy may up colon cancer survival

Diets high in dairy may up colon cancer survival

A diet rich in dairy products may slightly extend the lives of people diagnosed with colon cancer, a new study suggests.

Phase 1 trials begin for first-in-class anticancer drug

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Clinical trials have begun for PFK-158, a small-molecule therapeutic candidate that inactivates a novel cancer metabolism target never before examined in human clinical trials.

HBV therapy may reduce liver cancer risk

HBV therapy may reduce liver cancer risk

Antiviral treatment for hepatitis B virus (HBV) may be associated with a lower risk of hepatocellular carcinoma, researchers reported.

Enzyme from antidepressants may aid in developing prostate cancer treatments

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An enzyme commonly used as a target for antidepressants may also promote prostate cancer growth, according to an international team of scientists.

Potential new target for immunotherapy

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Scientists have found a way to target elusive cells that suppress immune response, depleting them with peptides that spare other important cells and shrink tumors in preclinical experiments, according to a new study.

Patients' symptom concerns before anticancer treatment predict symptom burdens

Patients' symptom concerns before anticancer treatment predict symptom burdens

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Patients who express pretreatment concern about treatment symptoms such as nausea and memory problems tend to suffer higher symptom burdens during and after anticancer treatment, suggests research.

No Cancer Prevention Benefit From Organic Food

No Cancer Prevention Benefit From Organic Food

A prospective survey found no reduction in cancer incidence in women eating organic food, but there's more to the story.

Single protein that shuts down pancreatic cancer growth is identified

Single protein that shuts down pancreatic cancer growth is identified

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Inhibiting a single protein completely shuts down the growth of pancreatic cancer, according to new research.

Some breast cancer tumors hijack epigenetic machinery to evade drugs

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A breast cancer therapy that blocks estrogen synthesis to activate cancer-killing genes sometimes loses its effectiveness because the cancer takes over epigenetic mechanisms, according to researchers.

How diabetes drugs may work against cancer

How diabetes drugs may work against cancer

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Scientists have identified a major mitochondrial pathway that allows cancer cells to survive in a low-glucose environment.

Unexpected cell-hijack method revealed in pancreatic cancer

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Pancreatic stellate cells, which normally aid tissue repair, unwittingly help pancreatic cancer grow and spread in a method of cell hijack only seen before in brain and breast cancer, according to new research. The research also revealed that the process can be blocked, thereby preventing the growth and spread of the tumor.

Promising new approach discovered to treat leukemia

Promising new approach discovered to treat leukemia

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A group of researchers discovered a promising new approach to treating leukemia by disarming a gene that is responsible for tumor progression.

Grape seed promising against colon cancer

Grape seed promising against colon cancer

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Grape seed can aid the effectiveness of chemotherapy in killing colon cancer cells as well as reducing chemotherapy side effects, according to new research.

Drug-resistant tumors made vulnerable with cyclophosphamide

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The drug cyclophosphamide may make recurrent tumors vulnerable again after they have developed resistance to cancer drugs that work by recruiting antibodies from the body's own immune system.

How do cancer cells thrive in low-oxygen tumors?

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A new study has identified the molecular pathway that enables cancer cells to grow in areas of a tumor where oxygen levels are low, a condition called hypoxia.

Early promise with new drug for cancers caused by viruses

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Specialized fat molecules, called sphingolipids, play a key role in the survival of aggressive lymphomas caused by viruses, according to new research.

BMH-21 demonstrates potential in shutting down common cancer process

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A previously known but little-studied chemical compound targets and shuts down a common cancer process, according to recent research. In studies of laboratory-grown human tumor cell lines, the drug disrupted tumor cell division and prevented growth of advanced cancer cells.

Drug-antibody pair has promising activity in non-Hodgkin lymphoma

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A toxin linked to a targeted monoclonal antibody has shown compelling antitumor activity in patients with non-Hodgkin lymphomas (NHLs) who were no longer responding to treatment, according to a new report.

Intestinal bacteria reinforce chemotherapy

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The intestinal flora stimulates an person's immune responses to combat cancer during chemotherapy, according to newly published research.

Less exercise leads to higher breast cancer mortality

Less exercise leads to higher breast cancer mortality

In addition to infrequent exercise, a larger breast cup size was also linked with increased risk of breast cancer mortality in female runners and walkers.

Imaging studies may predict tumor response to antiangiogenic drugs

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Advanced imaging techniques may be able to distinguish which patients' tumors will respond to treatment with antiangiogenic drugs and which will not.

Resistance mechanism of colorectal cancer to bevacizumab detailed

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When colorectal cancer is targeted by the drug bevacizumab, tumors may switch dependence from VEGF-A (targeted by the drug) to related growth factors that include VEGF-C, VEGF-D, and placental growth factor.

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