Anti-Cancer Activity

Breast cancer metastasis may be tied to cell that regulates blood flow

Breast cancer metastasis may be tied to cell that regulates blood flow

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Scientists believe that targeting blood vessel cells known as pericytes may offer a potential new therapeutic approach for breast and other cancers.

Oral bisphosphonate associated with decreased endometrial cancer risk

Oral bisphosphonate associated with decreased endometrial cancer risk

A reduction in endometrial cancer risk with oral bisphosphonate use in large cohort of postmenopausal women has been observed.

Cruciferous Vegetables and Cancer Prevention (Fact Sheet)

Cruciferous Vegetables and Cancer Prevention (Fact Sheet)

This fact sheet examines possible links between consumption of cruciferous vegetables and cancer prevention.

Health benefits linked to moderate drinking may be overestimated

Health benefits linked to moderate drinking may be overestimated

Previous studies linking moderate alcohol consumption to health benefits may have omitted some important details, according to British researchers.

New cancer-fighting strategy is to harden cells to prevent metastasis

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A new strategy that makes it more difficult for cancer cells to spread, rather than eliminating them outright, is being examined.

Cells that enhance tumor growth and suppress anticancer immune attack are identified

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Study results identified the population of white blood cells that tumors use to enhance growth and suppress the disease-fighting immune system, a step that can greater aid in immunotherapy development.

Less alcohol and plant-based diet can decrease obesity-related cancer risk

Less alcohol and plant-based diet can decrease obesity-related cancer risk

Research supports recent expert guidelines on an anti-cancer lifestyle from the World Cancer Research Fund and the American Institute for Cancer Research.

Oral inhibitor shows clinical activity in poor-prognosis acute myelogenous leukemia (AML)

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An oral targeted agent has shown encouraging activity and limited side effects in patients with treatment-resistant or relapsed acute myelogenous leukemia (AML), according to research.

Widely used osteoporosis drug may prevent breast, lung, and colon cancers

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The most commonly used medications for osteoporosis worldwide, bisphosphonates, may also prevent certain kinds of lung, breast, and colon cancers, according to two recent studies.

Targeting mitochondrial enzyme may reduce cardiac effects from chemotherapy drug

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Investigators have identified two compounds that appear to block the cardiac damage caused by doxorubicin. Their report indicates that inhibiting the action of an enzyme key to the generation of cellular energy in mitochondria could prevent doxorubicin-induced damage to cardiac cells without reducing the drug's antitumor effects.

A common antacid could lead to cheaper anticancer drugs

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A popular indigestion medication can increase survival in colorectal cancer; researchers have studied this effect for some time but the research conclusions may have been overlooked.

Prolonged TV watching may lower colorectal cancer survival chances

Prolonged TV watching may lower colorectal cancer survival chances

Researchers also found exercising seven hours or more a week boosted chances of living longer, whereas watching too much TV had the opposite effect.

Physical Activity and Cancer (Fact Sheet)

Physical Activity and Cancer (Fact Sheet)

This fact sheet examines the role of physical activity and exercise in cancer prevention and cancer survivorship.

Tea and Cancer Prevention (Fact Sheet)

Tea and Cancer Prevention (Fact Sheet)

This fact sheet explores the evidence that tea consumption may aid cancer prevention.

Antimalarial inhibits tumor growth and metastases

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A recent study has demonstrated that the malaria drug chloroquine normalizes the abnormal blood vessels in tumors, which can aid in blocking cancer cell dissemination and metastasis.

Chemoprotective effects of coffee

Chemoprotective effects of coffee

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Diet and nutrition are significant factors in preventing hepatic diseases progressing to hepatocellular carcinoma, and coffee is high on the list of good foods.

Bisphosphonate use may not prevent breast cancer

Bisphosphonate use may not prevent breast cancer

Data from two randomized controlled trials suggest that bisphosphonate use does not protect against postmenopausal breast cancer, according to research.

Prophylactic aspirin may aid cancer prevention

Prophylactic aspirin may aid cancer prevention

Daily aspirin appears beneficial for men and women between ages 50 and 65 in the general population.

Starch intake may counter colon-cancer risk from meat-heavy diet

Starch intake may counter colon-cancer risk from meat-heavy diet

So-called "resistant" starch, found in root vegetables, grains and legumes, may reverse some of the cancer risks of red meat consumption.

Some aggressive cancers may respond to anti-inflammatory drugs

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New research raises the prospect that some cancer patients with aggressive tumors may benefit from a class of anti-inflammatory drugs currently used to treat rheumatoid arthritis.

Antioxidants may not fight cancer, according to research

Antioxidants may not fight cancer, according to research

A research meta-analysis suggests that the anti-cancer properties of antioxidants may have been overstated, and that, in some cases, antioxidants could even have an adverse effect with regard to cancer.

The best cream for coffee may be the growing evidence of its cancer-preventive properties

The best cream for coffee may be the growing evidence of its cancer-preventive properties

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Can one of the most popular beverages in the world limit or even prevent the growth of certain cancers?

Antioxidants and Cancer Prevention (Fact Sheet)

Antioxidants and Cancer Prevention (Fact Sheet)

This fact sheet explores possible relationships between antioxidants and cancer prevention.

Antioxidants may not be an effective preventive measure against cancer

Antioxidants may not be an effective preventive measure against cancer

Researchers from the Lustgarten Foundation and Feinberg School of Medicine at Northwestern University offer an explanation of why antioxidant supplements may do more harm than good in regard to reducing cancer development.

Inhibitor of cholesterol biosynthesis may have potential as breast cancer treatment

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A compound initially developed as a treatment for high cholesterol not only halts the progression of breast cancer, but also can kill cancer cells.

Signalling pathway may send cancer's cellular factories into overdrive

Signalling pathway may send cancer's cellular factories into overdrive

Scientists identified a molecular trigger that prompts the unrestricted cell growth in cancer. A protein in the TOR signaling pathway, SREBP, controls the flow of messages to the endoplasmic reticulum (ER) to produce enough proteins and lipids to support nonstop growth.

Aspirin and smoking influence aging processes connected to cancer

Aspirin and smoking influence aging processes connected to cancer

Researchers from the University of Basel were able to show that aspirin use and smoking both influence aging processes of the female genome that are connected to colorectal cancer.

Limiting carbs may reduce breast cancer recurrence in some women

Limiting carbs may reduce breast cancer recurrence in some women

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Reducing carbohydrate intake could reduce the risk of breast cancer recurrence among women whose tumor tissue is positive for the insulin-like growth factor-1 (IGF1) receptor, according to a new study.

Diets high in dairy may up colon cancer survival

Diets high in dairy may up colon cancer survival

A diet rich in dairy products may slightly extend the lives of people diagnosed with colon cancer, a new study suggests.

Phase 1 trials begin for first-in-class anticancer drug

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Clinical trials have begun for PFK-158, a small-molecule therapeutic candidate that inactivates a novel cancer metabolism target never before examined in human clinical trials.

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