Anti-Cancer Activity

Affordable Care Act Changes in Medicare Drug Coverage May Not Be Enough to Defray the Costs of Oral Cancer Therapies

Affordable Care Act Changes in Medicare Drug Coverage May Not Be Enough to Defray the Costs of Oral Cancer Therapies

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Out-of-pocket costs for Medicare beneficiaries taking oral chemotherapy drugs are high, and despite changes in cost sharing due to the Affordable Care Act, those costs will remain high.

Novel Delivery Method Repurposes Existing Drug to Treat Liver Cancer

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An interdisciplinary collaboration between prominent academic and industry investigators discovered a novel method for repositioning an FDA-approved anticancer compound so it can specifically target liver cancer tumors.

Garlic and Cancer Prevention (Fact Sheet)

Garlic and Cancer Prevention (Fact Sheet)

This fact sheet explores links between garlic and cancer prevention, including study and clinical trials evidence and safety concerns.

Biogel Has Potential to Revolutionize Delivery of Anticancer Agents

Biogel Has Potential to Revolutionize Delivery of Anticancer Agents

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An injectable biogel effectively delivers anticancer agents directly into cancerous tumors. If successful in human patients, the modality has the potential to revolutionize cancer treatment.

Data Lacks Support for Anticancer Activity of Cannabis

Data Lacks Support for Anticancer Activity of Cannabis

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Patients periodically ask about the use of marijuana in cancer treatment. Is there any data about this?

Trabectedin Confers Long-Term Efficacy in Soft Tissue Sarcoma

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A large prospective postcommercialization study in patients with advanced STS in Europe confirmed the long-term anticancer activity of trabectedin (Yondelis) in different subtypes of sarcoma.

Molecule Inhibits Kinase Pair, Leading to Restored Normal Cell Function in Cancerous Cells

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A molecule isolated from sea sponges and later synthesized can halt the growth of cancerous cells, opening the door to a new treatment for leukemia.

Two-Drug Combination Shows Promise Against One Type of Pancreatic Cancer

Two-Drug Combination Shows Promise Against One Type of Pancreatic Cancer

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Researchers have shown that a certain protein becomes overabundant in pancreatic neuroendocrine tumors, allowing them to thrive. They also found that pairing a synthetic compound with an existing drug provides a more effective anticancer punch than a single drug.

Coffee consumption may improve survival in patients with colon cancer

Coffee consumption may improve survival in patients with colon cancer

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Regular consumption of caffeinated coffee may help prevent the return of colon cancer after treatment and improve the chances of a cure, according to a new, large study.

Study uses dog sledding to demonstrate benefits of adapted physical activities for children with cancer

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The results of a new preliminary study indicate that children with cancer may benefit from a different kind of treatment: a healthy dose of adventure.

Coffee consumption may lower risk of death in stage III colon cancer

Coffee consumption may lower risk of death in stage III colon cancer

Patients consuming 4 cups/day of caffeinated coffee have lower recurrence and mortality risk.

Reducing body fat through exercise can improve risks of breast cancer in postmenopausal women

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Postmenopausal women who exercised 300 minutes per week were better at reducing total fat, which could in turn lower their postmenopausal breast cancer risk.

Avocados may hold the answer to beating leukemia

Avocados may hold the answer to beating leukemia

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Can molecules derived from avocados be used as a tool to combat leukemia?

Researchers home in on what is wearing out T cells

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A new study indicates that the PD-1 protein pathway may niot be the only primary player in T cell exhaustion.

Pactomycin analogs offer new, gentler approach to cancer treatment

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Two promising analogs of an old compound originally studied as a potent antitumor agent may offer a new treatment for epithelial cancer.

Mediterranean diet could lessen endometrial cancer risk

Mediterranean diet could lessen endometrial cancer risk

Women who followed a Mediterranean-style diet saw a significant reduction in their risk of endometrial cancer, according to a new study.

Breastfeeding linked to lower childhood leukemia risk

Breastfeeding linked to lower childhood leukemia risk

One more potential benefit for breastfed babies, research suggests, is a lowered risk of childhood leukemia.

Video captures body's 'serial killers' destroying cancer cells

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A dramatic video has captured the behavior of cytotoxic T cells as they hunt down and eliminate cancer cells within the body.

Higher Vitamin D Concentrations Associated with Improved Survival in mCRC

Higher Vitamin D Concentrations Associated with Improved Survival in mCRC

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In patients with metastatic colorectal cancer treated with chemotherapy plus biologics, increased vitamin D levels have been linked to improved survival, according to information presented at the ASCO 2015 Annual Meeting.

More detailed findings confirm that coffee protects against breast cancer recurrence

More detailed findings confirm that coffee protects against breast cancer recurrence

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For women with breast cancer using the drug tamoxifen, coffee appears to both inhibit tumor growth and reduce recurrence.

Breast cancer metastasis may be tied to cell that regulates blood flow

Breast cancer metastasis may be tied to cell that regulates blood flow

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Scientists believe that targeting blood vessel cells known as pericytes may offer a potential new therapeutic approach for breast and other cancers.

Oral bisphosphonate associated with decreased endometrial cancer risk

Oral bisphosphonate associated with decreased endometrial cancer risk

A reduction in endometrial cancer risk with oral bisphosphonate use in large cohort of postmenopausal women has been observed.

Cruciferous Vegetables and Cancer Prevention (Fact Sheet)

Cruciferous Vegetables and Cancer Prevention (Fact Sheet)

This fact sheet examines possible links between consumption of cruciferous vegetables and cancer prevention.

Health benefits linked to moderate drinking may be overestimated

Health benefits linked to moderate drinking may be overestimated

Previous studies linking moderate alcohol consumption to health benefits may have omitted some important details, according to British researchers.

New cancer-fighting strategy is to harden cells to prevent metastasis

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A new strategy that makes it more difficult for cancer cells to spread, rather than eliminating them outright, is being examined.

Cells that enhance tumor growth and suppress anticancer immune attack are identified

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Study results identified the population of white blood cells that tumors use to enhance growth and suppress the disease-fighting immune system, a step that can greater aid in immunotherapy development.

Less alcohol and plant-based diet can decrease obesity-related cancer risk

Less alcohol and plant-based diet can decrease obesity-related cancer risk

Research supports recent expert guidelines on an anti-cancer lifestyle from the World Cancer Research Fund and the American Institute for Cancer Research.

Oral inhibitor shows clinical activity in poor-prognosis acute myelogenous leukemia (AML)

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An oral targeted agent has shown encouraging activity and limited side effects in patients with treatment-resistant or relapsed acute myelogenous leukemia (AML), according to research.

Widely used osteoporosis drug may prevent breast, lung, and colon cancers

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The most commonly used medications for osteoporosis worldwide, bisphosphonates, may also prevent certain kinds of lung, breast, and colon cancers, according to two recent studies.

Targeting mitochondrial enzyme may reduce cardiac effects from chemotherapy drug

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Investigators have identified two compounds that appear to block the cardiac damage caused by doxorubicin. Their report indicates that inhibiting the action of an enzyme key to the generation of cellular energy in mitochondria could prevent doxorubicin-induced damage to cardiac cells without reducing the drug's antitumor effects.

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