Anti-Cancer Activity

Researchers home in on what is wearing out T cells

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A new study indicates that the PD-1 protein pathway may niot be the only primary player in T cell exhaustion.

Pactomycin analogs offer new, gentler approach to cancer treatment

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Two promising analogs of an old compound originally studied as a potent antitumor agent may offer a new treatment for epithelial cancer.

Mediterranean diet could lessen endometrial cancer risk

Mediterranean diet could lessen endometrial cancer risk

Women who followed a Mediterranean-style diet saw a significant reduction in their risk of endometrial cancer, according to a new study.

Breastfeeding linked to lower childhood leukemia risk

Breastfeeding linked to lower childhood leukemia risk

One more potential benefit for breastfed babies, research suggests, is a lowered risk of childhood leukemia.

Video captures body's 'serial killers' destroying cancer cells

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A dramatic video has captured the behavior of cytotoxic T cells as they hunt down and eliminate cancer cells within the body.

Higher Vitamin D Concentrations Associated with Improved Survival in mCRC

Higher Vitamin D Concentrations Associated with Improved Survival in mCRC

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In patients with metastatic colorectal cancer treated with chemotherapy plus biologics, increased vitamin D levels have been linked to improved survival, according to information presented at the ASCO 2015 Annual Meeting.

More detailed findings confirm that coffee protects against breast cancer recurrence

More detailed findings confirm that coffee protects against breast cancer recurrence

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For women with breast cancer using the drug tamoxifen, coffee appears to both inhibit tumor growth and reduce recurrence.

Breast cancer metastasis may be tied to cell that regulates blood flow

Breast cancer metastasis may be tied to cell that regulates blood flow

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Scientists believe that targeting blood vessel cells known as pericytes may offer a potential new therapeutic approach for breast and other cancers.

Oral bisphosphonate associated with decreased endometrial cancer risk

Oral bisphosphonate associated with decreased endometrial cancer risk

A reduction in endometrial cancer risk with oral bisphosphonate use in large cohort of postmenopausal women has been observed.

Cruciferous Vegetables and Cancer Prevention (Fact Sheet)

Cruciferous Vegetables and Cancer Prevention (Fact Sheet)

This fact sheet examines possible links between consumption of cruciferous vegetables and cancer prevention.

Health benefits linked to moderate drinking may be overestimated

Health benefits linked to moderate drinking may be overestimated

Previous studies linking moderate alcohol consumption to health benefits may have omitted some important details, according to British researchers.

New cancer-fighting strategy is to harden cells to prevent metastasis

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A new strategy that makes it more difficult for cancer cells to spread, rather than eliminating them outright, is being examined.

Cells that enhance tumor growth and suppress anticancer immune attack are identified

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Study results identified the population of white blood cells that tumors use to enhance growth and suppress the disease-fighting immune system, a step that can greater aid in immunotherapy development.

Less alcohol and plant-based diet can decrease obesity-related cancer risk

Less alcohol and plant-based diet can decrease obesity-related cancer risk

Research supports recent expert guidelines on an anti-cancer lifestyle from the World Cancer Research Fund and the American Institute for Cancer Research.

Oral inhibitor shows clinical activity in poor-prognosis acute myelogenous leukemia (AML)

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An oral targeted agent has shown encouraging activity and limited side effects in patients with treatment-resistant or relapsed acute myelogenous leukemia (AML), according to research.

Widely used osteoporosis drug may prevent breast, lung, and colon cancers

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The most commonly used medications for osteoporosis worldwide, bisphosphonates, may also prevent certain kinds of lung, breast, and colon cancers, according to two recent studies.

Targeting mitochondrial enzyme may reduce cardiac effects from chemotherapy drug

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Investigators have identified two compounds that appear to block the cardiac damage caused by doxorubicin. Their report indicates that inhibiting the action of an enzyme key to the generation of cellular energy in mitochondria could prevent doxorubicin-induced damage to cardiac cells without reducing the drug's antitumor effects.

A common antacid could lead to cheaper anticancer drugs

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A popular indigestion medication can increase survival in colorectal cancer; researchers have studied this effect for some time but the research conclusions may have been overlooked.

Prolonged TV watching may lower colorectal cancer survival chances

Prolonged TV watching may lower colorectal cancer survival chances

Researchers also found exercising seven hours or more a week boosted chances of living longer, whereas watching too much TV had the opposite effect.

Physical Activity and Cancer (Fact Sheet)

Physical Activity and Cancer (Fact Sheet)

This fact sheet examines the role of physical activity and exercise in cancer prevention and cancer survivorship.

Tea and Cancer Prevention (Fact Sheet)

Tea and Cancer Prevention (Fact Sheet)

This fact sheet explores the evidence that tea consumption may aid cancer prevention.

Antimalarial inhibits tumor growth and metastases

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A recent study has demonstrated that the malaria drug chloroquine normalizes the abnormal blood vessels in tumors, which can aid in blocking cancer cell dissemination and metastasis.

Chemoprotective effects of coffee

Chemoprotective effects of coffee

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Diet and nutrition are significant factors in preventing hepatic diseases progressing to hepatocellular carcinoma, and coffee is high on the list of good foods.

Bisphosphonate use may not prevent breast cancer

Bisphosphonate use may not prevent breast cancer

Data from two randomized controlled trials suggest that bisphosphonate use does not protect against postmenopausal breast cancer, according to research.

Prophylactic aspirin may aid cancer prevention

Prophylactic aspirin may aid cancer prevention

Daily aspirin appears beneficial for men and women between ages 50 and 65 in the general population.

Starch intake may counter colon-cancer risk from meat-heavy diet

Starch intake may counter colon-cancer risk from meat-heavy diet

So-called "resistant" starch, found in root vegetables, grains and legumes, may reverse some of the cancer risks of red meat consumption.

Some aggressive cancers may respond to anti-inflammatory drugs

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New research raises the prospect that some cancer patients with aggressive tumors may benefit from a class of anti-inflammatory drugs currently used to treat rheumatoid arthritis.

Antioxidants may not fight cancer, according to research

Antioxidants may not fight cancer, according to research

A research meta-analysis suggests that the anti-cancer properties of antioxidants may have been overstated, and that, in some cases, antioxidants could even have an adverse effect with regard to cancer.

The best cream for coffee may be the growing evidence of its cancer-preventive properties

The best cream for coffee may be the growing evidence of its cancer-preventive properties

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Can one of the most popular beverages in the world limit or even prevent the growth of certain cancers?

Antioxidants and Cancer Prevention (Fact Sheet)

Antioxidants and Cancer Prevention (Fact Sheet)

This fact sheet explores possible relationships between antioxidants and cancer prevention.

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