ADD THIS DRUG TO MY LIST

Select the drug indication to add to your list

ANDRODERM
Hypogonadism
Compare To Related Drugs
View/Edit/Compare Drugs In My List

Only 4 drugs may be compared at once

Drug Name:

ANDRODERM CIII

Generic Name and Formulations:
Testosterone 2mg/day, 4mg/day; transdermal system.

Company:
Allergan

Therapeutic Use:

Indications for ANDRODERM:

Testosterone replacement therapy in adult males with congenital or acquired primary hypogonadism or hypogonadotropic hypogonadism.

Limitations Of use:

Not established in men with age-related hypogonadism.

Adult:

Prior to treatment, confirm diagnosis by ensuring serum testosterone is below normal range as measured in the AM on at least 2 separate days. ≥18yrs: initially apply one 4mg/day system nightly for 24hrs to intact clean, dry skin of the back, abdomen, thighs, or upper arms. Do not apply to scrotum; avoid bony prominences and areas subject to pressure during sleep or sitting. Rotate application sites at intervals of 7 days. Increase to 6mg (one 4mg/day + one 2mg/day system) or decrease to 2mg (one 2mg/day system) based on confirmed AM serum testosterone concentrations. Switching from 2.5mg/day, 5mg/day or 7.5mg/day systems: see full labeling.

Children:

<18yrs: not established.

Contraindications:

Male breast or prostate cancer. Pregnancy (Cat.X). Nursing mothers.

Warnings/Precautions:

Not for use in women. Monitor for worsening of signs/symptoms of BPH. Increased risk of prostate cancer; evaluate before starting therapy, at 3–6 months after, and then as necessary. Monitor hematocrit prior to initiation, at 3–6 months after starting therapy, then annually; if elevation occurs, withhold until acceptable level. Preexisting cardiac, renal or hepatic diseases. Obesity. Chronic lung disease. Testosterone and/or other anabolic androgenic steroid abuse. Monitor serum testosterone, PSA, liver function, cholesterol, lipid profile, serum calcium (in cancer patients at risk for hypercalcemia). Monitor for venous thromboembolism; discontinue if suspected. Inform patients of possible increased risk of MI, stroke. Remove system prior to undergoing MRI.

Interactions:

May alter insulin sensitivity and glycemic control. May affect oral anticoagulants; monitor INR, PT frequently. Increased fluid retention with concomitant ACTH, corticosteroids; monitor. May affect thyroid levels. Transdermal absorption reduced by pretreatment of triamcinolone ointment form.

Pharmacological Class:

Androgen.

Adverse Reactions:

Application site reactions (eg, pruritus, vesicles), back pain, chills, diarrhea, fatigue, GERD; polycythemia, edema, gynecomastia, sleep apnea, reduced sperm count, virilization in children.

How Supplied:

Systems 2mg/day—60; 4mg/day—30

Sign Up for Free e-newsletters

Regimen and Drug Listings

GET FULL LISTINGS OF TREATMENT Regimens and Drug INFORMATION

Bone Cancer Regimens Drugs
Brain Cancer Regimens Drugs
Breast Cancer Regimens Drugs
Endocrine Cancer Regimens Drugs
Gastrointestinal Cancer Regimens Drugs
Genitourinary Cancer Regimens Drugs
Gynecologic Cancer Regimens Drugs
Head and Neck Cancer Regimens Drugs
Hematologic Cancer Regimens Drugs
Lung Cancer Regimens Drugs
Other Cancers Regimens
Rare Cancers Regimens
Skin Cancer Regimens Drugs