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ALAVERT D-12 HOUR
Cough and cold
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Drug Name:

ALAVERT D-12 HOUR OTC

Generic Name and Formulations:
Loratadine 5mg, pseudoephedrine sulfate 120mg; ext-rel tabs.

Company:
Pfizer Inc.

Therapeutic Use:

Indications for ALAVERT D-12 HOUR:

Seasonal allergic rhinitis with nasal congestion.

Adult:

Swallow whole. 1 tab every 12 hrs.

Children:

Not recommended.

Contraindications:

Narrow-angle glaucoma. Urinary retention. Severe hypertension or coronary artery disease. During or within 14 days of MAOIs.

Warnings/Precautions:

Hepatic or renal impairment. Hypertension. Ischemic heart disease. Increased intraocular pressure. Thyroid disease. GI or GU obstruction. Seizures. Diabetes. Pregnancy (Cat.B). Nursing mothers: not recommended.

Interactions:

See Contraindications. Pseudoephedrine: Antagonizes antihypertensives. Increased ectopic pacemaker activity with digitalis.

Pharmacological Class:

Antihistamine + sympathomimetic.

Adverse Reactions:

Dry mouth, insomnia, somnolence, nervousness, dizziness, dyspepsia, pharyngitis, anorexia, bronchospasm.

Metabolism:

Loratadine: Hepatic (CYP3A4, 2D6); Pseudoephedrine: incompletely metabolized (less than 1%).

Elimination:

Renal, fecal.

Generic Availability:

YES

How Supplied:

Tabs—12, 24

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