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ADRENALIN
Anaphylaxis
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Drug Name:

ADRENALIN Rx

Generic Name and Formulations:
Epinephrine (as HCl) 1mg/mL; soln for IM or SC inj; contains sulfites.

Company:
Par Pharmaceutical, Inc.

Therapeutic Use:

Indications for ADRENALIN:

Emergency treatment of allergic reactions (Type I), including anaphylaxis. Bronchospasm. Urticaria. Angioedema. Serum sickness.

Adults and Children:

Do not dilute. Inject into the anterolateral aspect of the thigh. ≥30kg: 0.3–0.5mg SC or IM; max: 0.5mg per inj. <30kg: 0.01mg/kg SC or IM; max: 0.3mg per inj. Both: may repeat every 5–10 mins as necessary; rotate inj sites. Monitor clinically for reaction severity and cardiac effects.

Warnings/Precautions:

Avoid injecting into the buttocks, digits, hands, or feet. Cardio or cerebrovascular disease. Hypertension. Diabetes. Hyperthyroidism. Parkinson's disease, Pheochromocytoma. Elderly. Pregnancy (Cat.C). Labor & delivery. Nursing mothers.

Interactions:

Additive effects with concomitant other sympathomimetic agents. Caution with cardiac glycosides, digitalis, diuretics, quinidine, and other arrhythmia-producing agents; monitor. Pressor effects may be potentiated by tricyclic antidepressants, MAOIs, antihistamines, levothyroxine. May be antagonized by α-blockers (eg, phentolamine), β-blockers (eg, propranolol), ergots. Caution with halogenated hydrocarbon general anesthetics (eg, halothane). Do not use to counteract effects of phenothiazines.

Pharmacological Class:

Sympathomimetic.

Adverse Reactions:

Anxiety, apprehensiveness, restlessness, tremor, weakness, dizziness, sweating, palpitations, pallor, nausea, vomiting, headache, respiratory difficulties, angina, arrhythmias, ventricular fibrillation (may be fatal), rapid rises in BP, cerebral hemorrhage; rare: serious infections at the inj site.

How Supplied:

Single-dose vials (1mL)—25; Multi-dose vials (30mL)—1, 10

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