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ACZONE
Acne
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Drug Name:

ACZONE Rx

Generic Name and Formulations:
Dapsone 5%; gel.

Company:
Allergan

Therapeutic Use:

Indications for ACZONE:

Acne vulgaris.

Adult:

Wash skin and pat dry. Apply pea-sized amount to affected area in a thin layer twice daily in the AM & PM. Rub in gently and completely. Wash hands after use. Reevaluate if no improvement after 12 weeks.

Children:

Not established.

Warnings/Precautions:

Avoid in congenital or idiopathic methemoglobinemia. G6PD deficiency: may have increased risk of methemoglobinemia or hemolytic anemia; discontinue if occurs. Pregnancy (Cat.C). Nursing mothers: not recommended.

Interactions:

Increased risk of hemolysis in G6PD-deficient patients with concomitant trimethoprim/sulfamethoxazole, other folic acid antagonists (eg, pyrimethamine), anticonvulsants, rifampin, St. John's wort. Increased risk of methemoglobinemia with concomitant sulfonamides, acetaminophen, chloroquine, nitrates, nitrites, nitrofurantoin, phenobarbital, phenytoin, primaquine, quinine, and others. Skin/hair discoloration with topical benzoyl peroxide.

See Also:

ACZONE 7.5%

Pharmacological Class:

Sulfone.

Adverse Reactions:

Application site reactions (oiliness, peeling, dryness, erythema, pruritus).

Generic Availability:

NO

How Supplied:

Gel 5% (tubes)—60g, 90g; Gel 7.5% (pumps)—30g, 60g, 90g

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